MA40954A - Détermination de niveaux de glycosaminoglycane par spectrométrie de masse - Google Patents

Détermination de niveaux de glycosaminoglycane par spectrométrie de masse

Info

Publication number
MA40954A
MA40954A MA040954A MA40954A MA40954A MA 40954 A MA40954 A MA 40954A MA 040954 A MA040954 A MA 040954A MA 40954 A MA40954 A MA 40954A MA 40954 A MA40954 A MA 40954A
Authority
MA
Morocco
Prior art keywords
glycosaminoglycane
levels
determination
mass spectrometry
spectrometry
Prior art date
Application number
MA040954A
Other languages
English (en)
Inventor
Ann Barbier
Patrick Anthony John Haslett
Hicham Naimy
Yongchang Qiu
Original Assignee
Shire Human Genetic Therapies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetic Therapies filed Critical Shire Human Genetic Therapies
Publication of MA40954A publication Critical patent/MA40954A/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/042Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MA040954A 2014-11-14 2015-11-12 Détermination de niveaux de glycosaminoglycane par spectrométrie de masse MA40954A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462080154P 2014-11-14 2014-11-14

Publications (1)

Publication Number Publication Date
MA40954A true MA40954A (fr) 2017-09-19

Family

ID=54754780

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040954A MA40954A (fr) 2014-11-14 2015-11-12 Détermination de niveaux de glycosaminoglycane par spectrométrie de masse

Country Status (10)

Country Link
US (1) US10578624B2 (fr)
EP (1) EP3218722A1 (fr)
JP (1) JP6693954B2 (fr)
CN (1) CN107003324B (fr)
AU (1) AU2015346064B2 (fr)
CA (1) CA2967382A1 (fr)
EA (1) EA035784B1 (fr)
MA (1) MA40954A (fr)
MX (1) MX382410B (fr)
WO (1) WO2016077775A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6973714B2 (ja) * 2017-06-09 2021-12-01 国立大学法人北海道大学 ニーマン・ピック病c型の診断を補助する方法、ニーマン・ピック病c型に対する治療効果の判定を補助する方法並びにニーマン・ピック病c型治療薬のスクリーニング方法
MA50746A (fr) 2017-10-02 2020-08-12 Denali Therapeutics Inc Protéines de fusion comprenant des enzymes d'enzymothérapie substitutive
CN114965822B (zh) * 2017-10-27 2024-06-04 齐鲁制药有限公司 高效测定神经节苷脂gm1及其杂质的药物分析方法
CN107991414A (zh) * 2017-12-28 2018-05-04 山东大学 一种舒洛地特的电泳亲水相互作用色谱质谱联用检测方法
EP3842800A4 (fr) * 2018-08-21 2022-05-11 JCR Pharmaceuticals Co., Ltd. Procédé analytique pour le sulfate de chondroïtine
CN109541115B (zh) * 2018-11-28 2021-04-20 西北大学 唾液酸化糖链同分异构体的高分辨顺序分离和准确定量分析方法
WO2021039644A1 (fr) * 2019-08-23 2021-03-04 Jcrファーマ株式会社 PROCÉDÉ DE QUANTIFICATION D'Hex4, lyso-GM1, Fuc-GlcNAc-Asn, ET lyso-sulfataide INCLUS DANS LE LIQUIDE CÉPHALORACHIDIEN
CN111721872B (zh) * 2020-06-24 2021-06-25 山东大学 一种肝素与硫酸乙酰肝素的鉴别方法及应用
WO2022125560A1 (fr) * 2020-12-07 2022-06-16 The Nemours Foundation Élévation de glycosaminoglycanes chez des sujets sans mucopolysaccharidose
CN114689722A (zh) * 2020-12-31 2022-07-01 深圳市海普瑞药业集团股份有限公司 一种用于检测样品中糖胺聚糖羧酸化衍生物含量的方法及其应用
CN113092604B (zh) * 2021-03-18 2022-04-12 福建省水产研究所(福建水产病害防治中心) 水产品中三种常用麻醉剂的快速检测方法
CN115032377B (zh) * 2022-08-11 2022-11-01 裕菁科技(上海)有限公司 一种粘多糖贮积症生物标记物及应用
CN116256455B (zh) * 2023-03-20 2025-05-30 东营天东制药有限公司 鉴别猪肠黏膜来源肝素中牛肺来源肝素掺杂含量的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3698563B2 (ja) * 1998-09-22 2005-09-21 生化学工業株式会社 グリコサミノグリカンの測定方法及び測定キット
JP2003265196A (ja) * 2002-03-15 2003-09-24 Seikagaku Kogyo Co Ltd ムコ多糖症のスクリーニング方法
AUPS293002A0 (en) * 2002-06-14 2002-07-04 Women's And Children's Hospital Identification of oligosaccharides and their use in the diagnosis and evaluation of mucopolysaccharidoses and other related disorders
US20050238536A1 (en) * 2004-04-21 2005-10-27 Striepeke Steven K Device and method for measuring glycosaminoglycans in body fluids
JP4965999B2 (ja) * 2005-12-27 2012-07-04 セント ルイス ユニバーシティ ムコ多糖症の診断方法
US9029530B2 (en) * 2009-01-02 2015-05-12 Biomarin Pharmaceutical Inc. Detection of oligosaccharides
PL2593131T3 (pl) 2010-06-25 2020-01-31 Shire Human Genetic Therapies, Inc. Sposoby i kompozycje do dostarczania sulfatazy-2-iduronianiu do oun
CN104114686A (zh) * 2011-11-07 2014-10-22 夏尔人类遗传性治疗公司 Sanfilippo综合征的生物标志物及其用途
CN103713057B (zh) 2013-12-12 2015-07-08 中国海洋大学 一种降解硫酸乙酰肝素及检测其二糖组成的方法

Also Published As

Publication number Publication date
JP2017535774A (ja) 2017-11-30
JP6693954B2 (ja) 2020-05-13
CN107003324A (zh) 2017-08-01
WO2016077775A1 (fr) 2016-05-19
CN107003324B (zh) 2019-09-24
MX2017006242A (es) 2018-01-23
EA035784B1 (ru) 2020-08-10
US20170350900A1 (en) 2017-12-07
AU2015346064B2 (en) 2021-09-23
US10578624B2 (en) 2020-03-03
MX382410B (es) 2025-03-13
AU2015346064A1 (en) 2017-05-18
EP3218722A1 (fr) 2017-09-20
EA201790769A1 (ru) 2017-11-30
CA2967382A1 (fr) 2016-05-19

Similar Documents

Publication Publication Date Title
NL301117I2 (nl) trastuzumab deruxtecan
MA40954A (fr) Détermination de niveaux de glycosaminoglycane par spectrométrie de masse
GB201408392D0 (en) Mass Analyser
GB201616445D0 (en) Method of targeted mass spectrometric analysis
DE112015003177A5 (de) Zweimassenschwungrad
SG11201702040WA (en) Mass spectrometer
EP3334726A4 (fr) Compositions de plinabuline
EP3356831A4 (fr) Détection de bêta-amyloïde par spectrométrie de masse
EP3493241A4 (fr) Spectromètre de masse
PT3215530T (pt) Anticorpos de il-6 melhorados
EP3096791C0 (fr) Composés immunomodulateurs
DE112015002271A5 (de) Zweimassenschwungrad
DK3277690T3 (da) Spirocykliske forbindelser
EP3328991A4 (fr) Biosynthèse de polycétides
IL254502B (en) Solid forms of menaquinols
EP3338088A4 (fr) Biomarqueurs de coronaropathie
DK3385386T6 (da) Biosyntetisk carrimycin-gencluster
UY4467S (es) Frasco
GB2541346B (en) Mass spectrometer
FR3024647B1 (fr) Transat de puericulture
FI20146076A7 (fi) Suunnattu sirpalease
FR3029421B1 (fr) Diffuseur de parfum par un aegagrophile de posidonie
FR3019594B1 (fr) Section additionnelle de poussee
DK3391403T3 (da) Acceleratormassespektrometrifremgangsmåde
GB2536322B (en) Mass spectrometry analysis of protein variants