MA40957A - Inhibiteurs de biosynthèse d'héparane sulfate pour traiter des maladies - Google Patents
Inhibiteurs de biosynthèse d'héparane sulfate pour traiter des maladiesInfo
- Publication number
- MA40957A MA40957A MA040957A MA40957A MA40957A MA 40957 A MA40957 A MA 40957A MA 040957 A MA040957 A MA 040957A MA 40957 A MA40957 A MA 40957A MA 40957 A MA40957 A MA 40957A
- Authority
- MA
- Morocco
- Prior art keywords
- treat diseases
- biosynthesis inhibitors
- heparane
- sulphate
- heparane sulphate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462062036P | 2014-10-09 | 2014-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA40957A true MA40957A (fr) | 2017-09-19 |
Family
ID=55653801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA040957A MA40957A (fr) | 2014-10-09 | 2015-10-07 | Inhibiteurs de biosynthèse d'héparane sulfate pour traiter des maladies |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20190151312A1 (fr) |
| EP (1) | EP3204009A4 (fr) |
| JP (1) | JP2017530991A (fr) |
| KR (1) | KR20170072242A (fr) |
| CN (1) | CN107106561A (fr) |
| AR (1) | AR102213A1 (fr) |
| AU (1) | AU2015330846A1 (fr) |
| BR (1) | BR112017006705A2 (fr) |
| CA (1) | CA2963607A1 (fr) |
| IL (1) | IL251497A0 (fr) |
| MA (1) | MA40957A (fr) |
| MX (1) | MX2017004618A (fr) |
| RU (1) | RU2017115305A (fr) |
| TW (1) | TW201629051A (fr) |
| WO (1) | WO2016057834A1 (fr) |
| ZA (1) | ZA201703003B (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3348547T1 (sl) * | 2015-09-11 | 2020-10-30 | Sumitomo Dainippon Pharma Co., Ltd. | Derivati benzimidazola kot zaviralci NAV 1.7 (natrijevi kanalčki, napetostno odvisni, tip IX, podenota alfa (SCN9A)) za zdravljenje bolečine, disurije in multiple skleroze |
| WO2018177781A1 (fr) | 2017-03-28 | 2018-10-04 | Basf Se | Composés pesticides |
| GB201705263D0 (en) * | 2017-03-31 | 2017-05-17 | Probiodrug Ag | Novel inhibitors |
| CN109020957B (zh) * | 2017-06-12 | 2023-01-13 | 南京天印健华医药科技有限公司 | 作为mnk抑制剂的杂环化合物 |
| CN110582491B (zh) | 2017-06-30 | 2023-09-29 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
| JP7311228B2 (ja) * | 2017-06-30 | 2023-07-19 | ベイジン タイド ファーマシューティカル カンパニー リミテッド | Ｒｈｏ－関連プロテインキナーゼ阻害剤、それを含む医薬組成物並びにその調製方法及び使用 |
| KR102563325B1 (ko) | 2017-06-30 | 2023-08-03 | 베이징 타이드 파마슈티컬 코퍼레이션 리미티드 | Ｒｈｏ-관련 단백질 키나아제 억제제, Ｒｈｏ-관련 단백질 키나아제 억제제를 함유하는 약학 조성물, 제조 방법 및 약학 조성물의 용도 |
| CN107445899A (zh) * | 2017-07-19 | 2017-12-08 | 枣庄学院 | 一种苯并咪唑类化合物及其制备方法 |
| EP3675861A4 (fr) * | 2017-09-01 | 2021-01-06 | Kadmon Corporation, LLC | Inhibiteurs de protéine kinase à superenroulement d'hélices alpha (« coiled-coil ») associée à rho |
| JP7307729B2 (ja) | 2017-12-20 | 2023-07-12 | ヤンセン ファーマシューティカ エヌ．ベー． | メニン－ｍｌｌ相互作用のエキソ－アザスピロ阻害剤 |
| CN108997343A (zh) * | 2018-04-17 | 2018-12-14 | 丁敏 | 一种治疗小儿热性惊厥的药物组合物的制备方法 |
| CN108794470B (zh) * | 2018-07-25 | 2020-06-26 | 上海毕得医药科技有限公司 | 一种6-肼基-1H-吡唑并[3,4-b]吡啶及其下游产品的合成方法 |
| US11053501B2 (en) | 2018-11-30 | 2021-07-06 | The Penn State Research Foundation | Methods of treating neurodegenerative disease by inhibiting N-deacetylase N-sulfotransferase |
| WO2021096284A1 (fr) * | 2019-11-15 | 2021-05-20 | 일동제약(주) | Agoniste du récepteur glp-1 et son utilisation |
| EP4075980B1 (fr) | 2019-12-18 | 2025-07-23 | Stinginn LLC | 1,2,4-triazoles substitués et procédés d'utilisation |
| WO2021127282A1 (fr) * | 2019-12-18 | 2021-06-24 | Stinginn Llc | 1,2,4-triazoles substitués et procédés d'utilisation |
| US11897888B1 (en) | 2020-04-30 | 2024-02-13 | Stinginn Llc | Small molecular inhibitors of sting signaling compositions and methods of use |
| WO2025000053A1 (fr) * | 2023-06-28 | 2025-01-02 | Psylo Pty Ltd | Composés |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA013811B1 (ru) * | 2002-11-21 | 2010-08-30 | Новартис Вэксинес Энд Дайэгностикс, Инк. | 2,4,6-тризамещённые пиримидины, являющиеся ингибиторами фосфотидилинозитол(pi)-3-киназы, и их применение при лечении рака |
| WO2009066084A1 (fr) * | 2007-11-21 | 2009-05-28 | F. Hoffmann-La Roche Ag | 2-morpholinopyrimidines et leur utilisation en tant qu'inhibiteurs de kinase pi3 |
| MX2012015143A (es) * | 2010-06-30 | 2013-07-03 | Amgen Inc | Compuestos heterociclicos que contienen nitrogeno como inhibidores de pi3k delta. |
-
2015
- 2015-10-07 MA MA040957A patent/MA40957A/fr unknown
- 2015-10-08 BR BR112017006705A patent/BR112017006705A2/pt not_active Application Discontinuation
- 2015-10-08 AU AU2015330846A patent/AU2015330846A1/en not_active Abandoned
- 2015-10-08 TW TW104133270A patent/TW201629051A/zh unknown
- 2015-10-08 CA CA2963607A patent/CA2963607A1/fr not_active Abandoned
- 2015-10-08 MX MX2017004618A patent/MX2017004618A/es unknown
- 2015-10-08 AR ARP150103252A patent/AR102213A1/es unknown
- 2015-10-08 US US15/517,814 patent/US20190151312A1/en not_active Abandoned
- 2015-10-08 KR KR1020177012393A patent/KR20170072242A/ko not_active Withdrawn
- 2015-10-08 WO PCT/US2015/054761 patent/WO2016057834A1/fr not_active Ceased
- 2015-10-08 EP EP15848965.8A patent/EP3204009A4/fr not_active Withdrawn
- 2015-10-08 CN CN201580061705.7A patent/CN107106561A/zh active Pending
- 2015-10-08 RU RU2017115305A patent/RU2017115305A/ru unknown
- 2015-10-08 JP JP2017519311A patent/JP2017530991A/ja active Pending
-
2017
- 2017-04-02 IL IL251497A patent/IL251497A0/en unknown
- 2017-04-28 ZA ZA2017/03003A patent/ZA201703003B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016057834A9 (fr) | 2017-04-13 |
| BR112017006705A2 (pt) | 2017-12-26 |
| US20190151312A1 (en) | 2019-05-23 |
| RU2017115305A (ru) | 2018-11-14 |
| AU2015330846A1 (en) | 2017-05-18 |
| KR20170072242A (ko) | 2017-06-26 |
| ZA201703003B (en) | 2018-04-25 |
| CA2963607A1 (fr) | 2016-04-14 |
| EP3204009A4 (fr) | 2018-05-23 |
| IL251497A0 (en) | 2017-05-29 |
| CN107106561A (zh) | 2017-08-29 |
| EP3204009A1 (fr) | 2017-08-16 |
| MX2017004618A (es) | 2017-10-23 |
| JP2017530991A (ja) | 2017-10-19 |
| AR102213A1 (es) | 2017-02-15 |
| WO2016057834A1 (fr) | 2016-04-14 |
| TW201629051A (zh) | 2016-08-16 |
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