MA41298A - Procédés de marquage de banques codées par de l'adn - Google Patents

Procédés de marquage de banques codées par de l'adn

Info

Publication number
MA41298A
MA41298A MA041298A MA41298A MA41298A MA 41298 A MA41298 A MA 41298A MA 041298 A MA041298 A MA 041298A MA 41298 A MA41298 A MA 41298A MA 41298 A MA41298 A MA 41298A
Authority
MA
Morocco
Prior art keywords
dna
marking processes
coded bank
bank
coded
Prior art date
Application number
MA041298A
Other languages
English (en)
Inventor
Matthew Clark
Anthony D Keefe
Alexander Litovchick
Richard W Wagner
Original Assignee
X Chem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by X Chem Inc filed Critical X Chem Inc
Publication of MA41298A publication Critical patent/MA41298A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • C40B50/10—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support involving encoding steps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Structural Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA041298A 2014-12-30 2015-12-27 Procédés de marquage de banques codées par de l'adn MA41298A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462098037P 2014-12-30 2014-12-30

Publications (1)

Publication Number Publication Date
MA41298A true MA41298A (fr) 2017-11-07

Family

ID=56284965

Family Applications (1)

Application Number Title Priority Date Filing Date
MA041298A MA41298A (fr) 2014-12-30 2015-12-27 Procédés de marquage de banques codées par de l'adn

Country Status (15)

Country Link
US (1) US20180002688A1 (fr)
EP (1) EP3240795A4 (fr)
JP (1) JP6864621B2 (fr)
KR (1) KR20170094445A (fr)
CN (1) CN107428795B (fr)
AU (2) AU2015374309B2 (fr)
BR (1) BR112017013904A2 (fr)
CA (1) CA2972275A1 (fr)
EA (1) EA201791312A1 (fr)
HK (1) HK1246301A1 (fr)
IL (2) IL253154B (fr)
MA (1) MA41298A (fr)
MX (1) MX2017008772A (fr)
SG (1) SG11201705350XA (fr)
WO (1) WO2016109423A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11186836B2 (en) 2016-06-16 2021-11-30 Haystack Sciences Corporation Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules
WO2018195134A1 (fr) * 2017-04-18 2018-10-25 X-Chem, Inc. Méthodes d'identification de composés
US11795580B2 (en) 2017-05-02 2023-10-24 Haystack Sciences Corporation Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same
US11384376B2 (en) * 2018-05-31 2022-07-12 Roche Molecular Systems, Inc. Reagents and methods for post-synthetic modification of nucleic acids
CN110658163A (zh) * 2018-06-29 2020-01-07 成都先导药物开发股份有限公司 一种合成dna编码化合物中的反应监测方法
CN109468310B (zh) * 2018-10-25 2020-12-01 深圳劲宇生物科技有限公司 Dna编码碎片分子库的合成方法和连接基团的筛选方法
US20220145362A1 (en) * 2019-03-14 2022-05-12 Haystack Sciences Corporation Methods and systems for processing or analyzing oligonucleotide encoded molecules
CN112941634B (zh) * 2019-12-10 2023-09-26 成都先导药物开发股份有限公司 通过dna编码化合物库筛选同时结合多个生物靶标的化合物的方法
AU2021376394A1 (en) * 2020-11-06 2023-06-15 The University Of Chicago Hairpin oligonucleotides and uses thereof
WO2025053257A1 (fr) * 2023-09-07 2025-03-13 旭化成ファーマ株式会社 Procédé de production d'un composé codé par un oligonucléotide et utilisation associé

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996038726A1 (fr) * 1995-05-30 1996-12-05 Ecole Polytechnique Federale De Lausanne (Epfl) Couches doubles de phospholipides immobilisees par covalence sur des surfaces solides
DK3299463T3 (da) * 2002-10-30 2020-12-07 Nuevolution As Enzymatisk kodning
RU2470077C2 (ru) * 2003-12-17 2012-12-20 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Биологически активное соединение, содержащее кодирующий олигонуклеотид (варианты), способ его синтеза, библиотека соединений (варианты), способ ее синтеза и способ поиска соединения, связывающегося с биологической мишенью (варианты)
US8846883B2 (en) * 2011-08-16 2014-09-30 University Of Southhampton Oligonucleotide ligation
ES2675111T3 (es) * 2011-09-07 2018-07-06 X-Chem, Inc. Métodos para etiquetar bibliotecas con codificación de ADN
CN104685115A (zh) * 2012-07-13 2015-06-03 X-化学有限公司 具有聚合酶不可读的编码性寡核苷酸连接的dna编码文库

Also Published As

Publication number Publication date
EA201791312A1 (ru) 2017-10-31
AU2015374309B2 (en) 2020-06-11
IL253154B (en) 2020-10-29
EP3240795A4 (fr) 2019-02-13
IL253154A0 (en) 2017-08-31
SG11201705350XA (en) 2017-08-30
US20180002688A1 (en) 2018-01-04
BR112017013904A2 (pt) 2018-01-02
WO2016109423A1 (fr) 2016-07-07
AU2020230345A1 (en) 2020-10-01
JP2018501796A (ja) 2018-01-25
MX2017008772A (es) 2018-03-15
KR20170094445A (ko) 2017-08-17
JP6864621B2 (ja) 2021-04-28
HK1246301A1 (zh) 2018-09-07
EP3240795A1 (fr) 2017-11-08
CN107428795A (zh) 2017-12-01
CA2972275A1 (fr) 2016-07-07
IL278117A (en) 2020-11-30
WO2016109423A8 (fr) 2017-07-20
CN107428795B (zh) 2021-06-18
AU2015374309A1 (en) 2017-07-27

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