MA42060A - Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate - Google Patents

Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate

Info

Publication number
MA42060A
MA42060A MA042060A MA42060A MA42060A MA 42060 A MA42060 A MA 42060A MA 042060 A MA042060 A MA 042060A MA 42060 A MA42060 A MA 42060A MA 42060 A MA42060 A MA 42060A
Authority
MA
Morocco
Prior art keywords
membranary
fibronectines
antigen
specific
type iii
Prior art date
Application number
MA042060A
Other languages
English (en)
Inventor
Rosa Cardoso
Michael Diem
Shalom Goldberg
Linus Hyun
Steven Jacobs
Donna Klein
Karyn O'neil
Tracy Spinka-Doms
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA42060A publication Critical patent/MA42060A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57555Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA042060A 2015-05-06 2016-05-06 Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate MA42060A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562157772P 2015-05-06 2015-05-06

Publications (1)

Publication Number Publication Date
MA42060A true MA42060A (fr) 2018-03-14

Family

ID=57217949

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042060A MA42060A (fr) 2015-05-06 2016-05-06 Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate

Country Status (12)

Country Link
US (2) US10844111B2 (fr)
EP (1) EP3292222B1 (fr)
JP (2) JP7366518B2 (fr)
KR (1) KR102625793B1 (fr)
CN (1) CN107849116A (fr)
AU (2) AU2016258174B2 (fr)
CA (1) CA2985138A1 (fr)
EA (1) EA201792441A2 (fr)
HK (1) HK1253005A1 (fr)
IL (1) IL255425B2 (fr)
MA (1) MA42060A (fr)
WO (1) WO2016179534A2 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102754019B1 (ko) 2014-10-29 2025-01-14 바이시클러드 리미티드 Mt1-mmp에 특이적인 바이사이클릭 펩타이드 리간드
JP7685735B2 (ja) 2016-12-02 2025-05-30 アンヘレス セラピューティクス インコーポレイテッド 合成免疫受容体およびその使用方法
BR112019012154A2 (pt) 2016-12-14 2019-11-12 Janssen Biotech, Inc. domínios do tipo iii da fibronectina de ligação a cd8a
EP3554561B1 (fr) 2016-12-14 2023-06-28 Janssen Biotech, Inc. Domaines de fibronectine de type iii à liaison au cd137
EP3554535A4 (fr) 2016-12-14 2020-10-21 Janssen Biotech, Inc. Domaines de fibronectine de type iii se liant à pd-l1
CN111032678A (zh) 2017-06-26 2020-04-17 拜西克尔德有限公司 具有可检测部分的双环肽配体和其用途
JP7280238B2 (ja) * 2017-07-17 2023-05-23 ヤンセン バイオテツク,インコーポレーテツド フィブロネクチンiii型ドメインに対する抗原結合領域及びその使用方法
ES2926195T3 (es) 2017-08-04 2022-10-24 Bicycletx Ltd Ligandos peptídicos bicíclicos específicos de CD137
CA3074317C (fr) * 2017-08-25 2024-06-18 Janssen Biotech, Inc. Domaines de type iii de fibronectine liant fc.gamma.rii, leurs conjugues et molecules multispecifiques les comprenant
US20190175651A1 (en) * 2017-12-13 2019-06-13 Janssen Biotech, Inc. Immortalized car-t cells genetically modified to elminate t-cell receptor and beta 2-microglobulin expression
US20190184028A1 (en) * 2017-12-14 2019-06-20 Janssen Biotech, Inc. Targeting with firbronectin type iii like domain molecules
AU2019224659A1 (en) 2018-02-23 2020-10-15 Bicycletx Limited Multimeric bicyclic peptide ligands
WO2019173636A1 (fr) * 2018-03-07 2019-09-12 Poseida Therapeutics, Inc. Compositions de cartyrin et méthodes d'utilisation
MA52777A (fr) * 2018-05-24 2021-04-14 Janssen Biotech Inc Agents de liaison psma et utilisations correspondantes
US11180531B2 (en) 2018-06-22 2021-11-23 Bicycletx Limited Bicyclic peptide ligands specific for Nectin-4
GB201810325D0 (en) * 2018-06-22 2018-08-08 Bicycletx Ltd Peptide ligands for binding to PSMA
GB201820325D0 (en) * 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
CN113498439A (zh) * 2018-12-20 2021-10-12 波赛达治疗公司 纳米转座子组合物及使用方法
CN113474045A (zh) 2018-12-21 2021-10-01 拜斯科技术开发有限公司 Pd-l1特异性的双环肽配体
US12551567B2 (en) 2018-12-21 2026-02-17 Bicyclerd Limited Bicyclic peptide ligands specific for PD-L1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
BR112021017863A2 (pt) * 2019-04-10 2022-01-04 Navigo Proteins Gmbh Proteína de ligação de antígeno de membrana específico de próstata, composição, método para produzir a proteína de ligação de antígeno de membrana específico de próstata
AR118720A1 (es) 2019-04-19 2021-10-27 Janssen Biotech Inc Métodos para tratar el cáncer de próstata con un anticuerpo anti-psma / cd3
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
US11781138B2 (en) 2019-10-14 2023-10-10 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
WO2021076546A1 (fr) 2019-10-14 2021-04-22 Aro Biotherapeutics Company Domaines de type iii de fibronectine de liaison à cd137
US12491255B2 (en) 2019-10-14 2025-12-09 Aro Biotherapeutics Company EPCAM binding fibronectin type III domains
EP4146805A2 (fr) * 2020-05-05 2023-03-15 ARO Biotherapeutics Company Domaines iii de la fibronectine de liaison à l'antigène membranaire spécifique de la prostate et cellules les comprenant
CA3189761A1 (fr) 2020-08-03 2022-02-10 Gemma Mudd Lieurs a base de peptides
IL307582A (en) 2021-04-14 2023-12-01 Aro Biotherapeutics Company CD71-binding domains of the fibronectin type
US12239710B2 (en) 2021-04-14 2025-03-04 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
MX2024002479A (es) * 2021-08-27 2024-05-28 Janssen Biotech Inc Radioconjugados anti-psma y usos de estos.
KR20240049342A (ko) 2021-08-27 2024-04-16 얀센 바이오테크 인코포레이티드 항-psma 항체 및 이의 용도
US20250052944A1 (en) 2022-01-11 2025-02-13 Sumitomo Electric Industries, Ltd. Method for producing multicore optical fiber, and multicore optical fiber
CN114940710B (zh) * 2022-06-07 2023-09-26 恺佧生物科技(上海)有限公司 一种提高重组人psma蛋白表达的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
ES2118066T3 (es) 1989-10-05 1998-09-16 Optein Inc Sintesis y aislamiento, exentos de celulas, de nuevos genes y polipeptidos.
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
PT1696031E (pt) 1991-12-02 2010-06-25 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
AU5670194A (en) 1992-11-20 1994-06-22 Enzon, Inc. Linker for linked fusion polypeptides
US5635483A (en) 1992-12-03 1997-06-03 Arizona Board Of Regents Acting On Behalf Of Arizona State University Tumor inhibiting tetrapeptide bearing modified phenethyl amides
US5780588A (en) 1993-01-26 1998-07-14 Arizona Board Of Regents Elucidation and synthesis of selected pentapeptides
JP3614866B2 (ja) 1997-06-12 2005-01-26 リサーチ コーポレイション テクノロジーズ,インコーポレイティド 人工抗体ポリペプチド
US5981209A (en) 1997-12-04 1999-11-09 Guilford Pharmaceuticals Inc. Use of NAALADase activity to identify prostate cancer and benign prostatic hyperplasia
US6472147B1 (en) 1999-05-25 2002-10-29 The Scripps Research Institute Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries
US20130226834A1 (en) 2000-04-27 2013-08-29 Networth Services, Inc. Systems and methods for determining the financial status of bonds
EP2141243A3 (fr) * 2000-10-16 2010-01-27 Brystol-Myers Squibb Company Supports de protéine pour mimer des anticorps et d'autres protéines de liaison
US6884869B2 (en) 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
US6884907B2 (en) 2001-05-11 2005-04-26 Guilford Pharmaceuticals Inc. Hydroxamic acids and acyl hydroxamines as naaladase inhibitors
JP4602614B2 (ja) 2001-09-26 2010-12-22 アイシン精機株式会社 自動車用ドア
US7842476B2 (en) 2002-09-06 2010-11-30 Isogenica Limited In vitro peptide expression library
JP5537946B2 (ja) * 2006-11-22 2014-07-02 ブリストル−マイヤーズ スクイブ カンパニー Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬
JP2011507519A (ja) 2007-12-19 2011-03-10 セントコア・オーソ・バイオテツク・インコーポレーテツド pIX又はpVIIへの融合を介したヒトデノボpIXファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法
JP2011507521A (ja) 2007-12-19 2011-03-10 セントコア・オーソ・バイオテツク・インコーポレーテツド ヒト非抗体ペプチド又はタンパク質ファージライブラリ
BRPI0919881B1 (pt) 2008-10-31 2021-09-08 Centocor Ortho Biotech Inc Proteína de arcabouço e seu método de geração, biblioteca e seu método de construção, molécula de ácido nucleico, vetor de ácido nucleico, célula hospedeira, composição, dispositivo médico e artigo de fabricação
JP5997134B2 (ja) * 2010-04-30 2016-09-28 ヤンセン バイオテツク,インコーポレーテツド 安定したフィブロネクチンドメイン組成物、方法及び用途
WO2012162418A1 (fr) * 2011-05-23 2012-11-29 The University Of North Carolina At Chapel Hill Procédés et compositions pour ligands de ciblage hétérodimères
JP5997151B2 (ja) * 2011-06-30 2016-09-28 中外製薬株式会社 ヘテロ二量化ポリペプチド
BR112014007469B1 (pt) 2011-09-27 2022-06-14 Janssen Biotech, Inc Método de fabricação de uma biblioteca de domínios de módulo de fibronectina tipo iii (fn3), biblioteca e método para obter um arcabouço de proteína
US9695228B2 (en) * 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules
KR20160097294A (ko) 2013-12-09 2016-08-17 뉴욕 유니버시티 항-포도상구균 제제의 식세포 전달을 위한 조성물 및 방법
WO2016179518A2 (fr) * 2015-05-06 2016-11-10 Janssen Biotech, Inc. Agents de liaison bispécifique à l'antigène membranaire spécifique de la prostate (psma) et utilisations de ceux-ci

Also Published As

Publication number Publication date
AU2016258174B2 (en) 2022-01-20
EP3292222A2 (fr) 2018-03-14
AU2022202637A1 (en) 2022-05-12
KR102625793B1 (ko) 2024-01-15
WO2016179534A2 (fr) 2016-11-10
JP7366518B2 (ja) 2023-10-23
AU2016258174A1 (en) 2017-11-23
EA201792441A2 (ru) 2018-06-29
US12054534B2 (en) 2024-08-06
JP2018515087A (ja) 2018-06-14
CA2985138A1 (fr) 2016-11-10
BR112017023798A2 (en) 2018-10-16
KR20180002780A (ko) 2018-01-08
JP2022002526A (ja) 2022-01-11
EP3292222A4 (fr) 2018-10-17
US10844111B2 (en) 2020-11-24
US20160326232A1 (en) 2016-11-10
US20210147510A1 (en) 2021-05-20
IL255425B2 (en) 2023-10-01
IL255425A0 (en) 2017-12-31
HK1253005A1 (zh) 2019-06-06
EP3292222B1 (fr) 2025-09-03
JP7307133B2 (ja) 2023-07-11
IL255425B1 (en) 2023-06-01
CN107849116A (zh) 2018-03-27

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