MA42060A - Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate - Google Patents

Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate

Info

Publication number
MA42060A
MA42060A MA042060A MA42060A MA42060A MA 42060 A MA42060 A MA 42060A MA 042060 A MA042060 A MA 042060A MA 42060 A MA42060 A MA 42060A MA 42060 A MA42060 A MA 42060A
Authority
MA
Morocco
Prior art keywords
membranary
fibronectines
antigen
specific
type iii
Prior art date
Application number
MA042060A
Other languages
English (en)
Inventor
Rosa Cardoso
Michael Diem
Shalom Goldberg
Linus Hyun
Steven Jacobs
Donna Klein
Karyn O'neil
Tracy Spinka-Doms
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA42060A publication Critical patent/MA42060A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA042060A 2015-05-06 2016-05-06 Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate MA42060A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562157772P 2015-05-06 2015-05-06

Publications (1)

Publication Number Publication Date
MA42060A true MA42060A (fr) 2018-03-14

Family

ID=57217949

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042060A MA42060A (fr) 2015-05-06 2016-05-06 Domaines de type iii de fibronectines fixant l'antigène membranaire spécifique de la prostate

Country Status (12)

Country Link
US (2) US10844111B2 (fr)
EP (1) EP3292222B1 (fr)
JP (2) JP7366518B2 (fr)
KR (1) KR102625793B1 (fr)
CN (1) CN107849116A (fr)
AU (2) AU2016258174B2 (fr)
CA (1) CA2985138A1 (fr)
EA (1) EA201792441A2 (fr)
HK (1) HK1253005A1 (fr)
IL (1) IL255425B2 (fr)
MA (1) MA42060A (fr)
WO (1) WO2016179534A2 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201702845QA (en) 2014-10-29 2017-05-30 Bicycle Therapeutics Ltd Bicyclic peptide ligands specific for mt1-mmp
KR20250072712A (ko) 2016-12-02 2025-05-26 앤젤레스 테라퓨틱스, 인코포레이티드 합성 면역 수용체 및 이의 사용 방법
EP3554561B1 (fr) 2016-12-14 2023-06-28 Janssen Biotech, Inc. Domaines de fibronectine de type iii à liaison au cd137
AU2017378226A1 (en) 2016-12-14 2019-06-20 Janssen Biotech, Inc. CD8A-binding fibronectin type III domains
US10597438B2 (en) 2016-12-14 2020-03-24 Janssen Biotech, Inc. PD-L1 binding fibronectin type III domains
US10899798B2 (en) 2017-06-26 2021-01-26 Bicyclerd Limited Bicyclic peptide ligands with detectable moieties and uses thereof
KR102869563B1 (ko) * 2017-07-17 2025-10-10 얀센 바이오테크 인코포레이티드 피브로넥틴 iii형 도메인에 대한 항원 결합 영역 및 이의 사용 방법
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Ｃｄ１３７に対して特異的な二環式ペプチドリガンド
EP3672611A4 (fr) * 2017-08-25 2021-07-14 Janssen Biotech, Inc. DOMAINES DE TYPE III DE FIBRONECTINE LIANT FCyRII, LEURS CONJUGUÉS ET MOLÉCULES MULTISPÉCIFIQUES LES COMPRENANT
AU2018386010A1 (en) * 2017-12-13 2020-05-14 Janssen Biotech, Inc. Immortalized car-T cells genetically modified to eliminate t-cell receptor and beta 2-microglobulin expression
US20190184028A1 (en) * 2017-12-14 2019-06-20 Janssen Biotech, Inc. Targeting with firbronectin type iii like domain molecules
US10875894B2 (en) 2018-02-23 2020-12-29 Bicycletx Limited Multimeric bicyclic peptide ligands
US20210107993A1 (en) * 2018-03-07 2021-04-15 Poseida Therapeutics, Inc. Cartyrin compositions and methods for use
CN112513085B (zh) * 2018-05-24 2024-06-18 詹森生物科技公司 Psma结合剂及其用途
IL279489B2 (en) 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
GB201810325D0 (en) * 2018-06-22 2018-08-08 Bicycletx Ltd Peptide ligands for binding to PSMA
GB201820325D0 (en) * 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
WO2020132396A1 (fr) * 2018-12-20 2020-06-25 Poseida Therapeutics, Inc. Compositions de nanotransposons et procédés d'utilisation
CN113260420A (zh) 2018-12-21 2021-08-13 拜斯科阿迪有限公司 Pd-l1特异性的双环肽配体
CN113474045A (zh) 2018-12-21 2021-10-01 拜斯科技术开发有限公司 Pd-l1特异性的双环肽配体
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
US20220168386A1 (en) * 2019-04-10 2022-06-02 Navigo Proteins Gmbh Novel psma specific binding proteins for cancer diagnosis and treatment
BR112021020532A2 (pt) 2019-04-19 2022-03-15 Janssen Biotech Inc Métodos para tratamento de câncer de próstata com um anticorpo anti-psma/cd3
TWI862640B (zh) 2019-07-30 2024-11-21 英商拜西可泰克斯有限公司 異質雙環肽複合物
US11628222B2 (en) 2019-10-14 2023-04-18 Aro Biotherapeutics Company CD71 binding fibronectin type III domains
WO2021076543A1 (fr) 2019-10-14 2021-04-22 Aro Biotherapeutics Company Domaines de type iii de fibronectine de liaison à cd137
US11781138B2 (en) 2019-10-14 2023-10-10 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
CN115884778A (zh) * 2020-05-05 2023-03-31 Aro生物疗法公司 与前列腺特异性膜抗原结合的纤连蛋白iii型结构域和包含该结构域的细胞
CN116348476A (zh) 2020-08-03 2023-06-27 拜斯科技术开发有限公司 基于肽的接头
AU2022258584A1 (en) 2021-04-14 2023-10-12 Aro Biotherapeutics Company Fn3 domain-sirna conjugates and uses thereof
TW202304971A (zh) 2021-04-14 2023-02-01 美商亞羅生物治療公司 結合cd71之纖連蛋白iii型結構域
CN118176213B (zh) 2021-08-27 2025-09-23 詹森生物科技公司 抗psma抗体及其用途
TW202327660A (zh) * 2021-08-27 2023-07-16 美商健生生物科技公司 抗ｐｓｍａ放射接合物及其用途
EP4464672A4 (fr) 2022-01-11 2025-04-23 Sumitomo Electric Industries, Ltd. Procédé de production de fibre optique multicoeur, et fibre optique multicoeur
CN114940710B (zh) * 2022-06-07 2023-09-26 恺佧生物科技(上海)有限公司 一种提高重组人psma蛋白表达的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DK0494955T3 (da) 1989-10-05 1998-10-26 Optein Inc Cellefri syntese og isolering af hidtil ukendte gener og polypeptider
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
ES2341666T3 (es) 1991-12-02 2010-06-24 Medimmune Limited Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
AU5670194A (en) 1992-11-20 1994-06-22 Enzon, Inc. Linker for linked fusion polypeptides
US5635483A (en) 1992-12-03 1997-06-03 Arizona Board Of Regents Acting On Behalf Of Arizona State University Tumor inhibiting tetrapeptide bearing modified phenethyl amides
US5780588A (en) 1993-01-26 1998-07-14 Arizona Board Of Regents Elucidation and synthesis of selected pentapeptides
CA2293632C (fr) 1997-06-12 2011-11-29 Research Corporation Technologies, Inc. Polypeptides d'anticorps artificiels
US5981209A (en) 1997-12-04 1999-11-09 Guilford Pharmaceuticals Inc. Use of NAALADase activity to identify prostate cancer and benign prostatic hyperplasia
US6472147B1 (en) 1999-05-25 2002-10-29 The Scripps Research Institute Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries
US20130226834A1 (en) 2000-04-27 2013-08-29 Networth Services, Inc. Systems and methods for determining the financial status of bonds
WO2002032925A2 (fr) * 2000-10-16 2002-04-25 Phylos, Inc. Echafaudages proteiniques internes pour analogues d'anticorps et autres proteines de liaison
US6884869B2 (en) 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
US6884907B2 (en) 2001-05-11 2005-04-26 Guilford Pharmaceuticals Inc. Hydroxamic acids and acyl hydroxamines as naaladase inhibitors
JP4602614B2 (ja) 2001-09-26 2010-12-22 アイシン精機株式会社 自動車用ドア
PT1534830E (pt) 2002-09-06 2011-01-31 Isogenica Ltd Biblioteca de expressão de péptidos in vitro
JP5537946B2 (ja) * 2006-11-22 2014-07-02 ブリストル−マイヤーズ スクイブ カンパニー Ｉｇｆ−ｉｒを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬
JP2011507519A (ja) 2007-12-19 2011-03-10 セントコア・オーソ・バイオテツク・インコーポレーテツド ｐＩＸ又はｐＶＩＩへの融合を介したヒトデノボｐＩＸファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法
US20110118144A1 (en) 2007-12-19 2011-05-19 Linus Hyun Engineered phage vectors for the design and the generation of a human non-antibody peptide or protein phage library via fusion to pix of m13 phage
CN102307896B (zh) * 2008-10-31 2016-10-12 森托科尔奥索生物科技公司 基于iii型纤连蛋白结构域的支架组合物、方法及用途
SI2571531T1 (sl) 2010-04-30 2016-09-30 Janssen Biotech, Inc. Stabilizirani sestavki fibronektinske domene, postopki in uporabe
WO2012162418A1 (fr) * 2011-05-23 2012-11-29 The University Of North Carolina At Chapel Hill Procédés et compositions pour ligands de ciblage hétérodimères
RU2641256C2 (ru) * 2011-06-30 2018-01-16 Чугаи Сейяку Кабусики Кайся Гетеродимеризованный полипептид
KR102035713B1 (ko) * 2011-09-27 2019-10-24 얀센 바이오테크 인코포레이티드 대체 결합 표면을 가진 피브로넥틴 유형 iii 반복체 기반의 단백질 스캐폴드
US9695228B2 (en) * 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules
AU2014363987A1 (en) * 2013-12-09 2016-06-30 Janssen Biotech, Inc. Compositions and methods for phagocyte delivery of anti-staphylococcal agents
WO2016179518A2 (fr) * 2015-05-06 2016-11-10 Janssen Biotech, Inc. Agents de liaison bispécifique à l'antigène membranaire spécifique de la prostate (psma) et utilisations de ceux-ci

Also Published As

Publication number Publication date
US20210147510A1 (en) 2021-05-20
IL255425B2 (en) 2023-10-01
KR20180002780A (ko) 2018-01-08
BR112017023798A2 (en) 2018-10-16
JP7307133B2 (ja) 2023-07-11
JP2022002526A (ja) 2022-01-11
AU2016258174A1 (en) 2017-11-23
IL255425A0 (en) 2017-12-31
EA201792441A2 (ru) 2018-06-29
EP3292222B1 (fr) 2025-09-03
US10844111B2 (en) 2020-11-24
US20160326232A1 (en) 2016-11-10
HK1253005A1 (zh) 2019-06-06
AU2016258174B2 (en) 2022-01-20
IL255425B1 (en) 2023-06-01
KR102625793B1 (ko) 2024-01-15
CN107849116A (zh) 2018-03-27
JP7366518B2 (ja) 2023-10-23
EP3292222A2 (fr) 2018-03-14
CA2985138A1 (fr) 2016-11-10
EP3292222A4 (fr) 2018-10-17
JP2018515087A (ja) 2018-06-14
WO2016179534A2 (fr) 2016-11-10
AU2022202637A1 (en) 2022-05-12
US12054534B2 (en) 2024-08-06

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