MA42111B1 - Topical pharmaceutical compositions - Google Patents

Topical pharmaceutical compositions

Info

Publication number
MA42111B1
MA42111B1 MA42111A MA42111A MA42111B1 MA 42111 B1 MA42111 B1 MA 42111B1 MA 42111 A MA42111 A MA 42111A MA 42111 A MA42111 A MA 42111A MA 42111 B1 MA42111 B1 MA 42111B1
Authority
MA
Morocco
Prior art keywords
topical pharmaceutical
pharmaceutical compositions
patient
compositions
condition
Prior art date
Application number
MA42111A
Other languages
French (fr)
Other versions
MA42111A (en
Inventor
Mary BEDARD
Michael Quinn DOHERTY
Jon D Lenn
Leandro L Santos
Sujatha D Sonti
Joey Roger THOMAS
Justin E Whiteman
Piyush Jain
Original Assignee
Dermavant Sciences GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermavant Sciences GmbH filed Critical Dermavant Sciences GmbH
Priority claimed from PCT/IB2016/052955 external-priority patent/WO2016185428A1/en
Publication of MA42111A publication Critical patent/MA42111A/en
Publication of MA42111B1 publication Critical patent/MA42111B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne des compositions d'émulsion pharmaceutiques topiques qui comprennent une quantité thérapeutiquement efficace de 3,5-dihydroxy-4-isopropyl-trans-stilbène, ou un de ses sels de qualité pharmaceutique, une phase huileuse, une phase aqueuse, un tensioactif et un antioxydant, la composition d'émulsion étant homogène et/ou l'agent actif étant solubilisé dans la phase huileuse. L'invention concerne également des procédés de traitement d'une affection ou d'une pathologie dermatologique chez un patient par l'application desdites compositions sur la peau du patient.The present invention relates to topical pharmaceutical emulsion compositions which comprise a therapeutically effective amount of 3,5-dihydroxy-4-isopropyl-trans-stilbene, or a pharmaceutical grade salt thereof, an oil phase, an aqueous phase, a surfactant and an antioxidant, the emulsion composition being homogeneous and/or the active agent being dissolved in the oily phase. Also provided are methods of treating a dermatological condition or condition in a patient by applying said compositions to the patient's skin.

MA42111A 2015-05-21 2016-05-19 Topical pharmaceutical compositions MA42111B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562165097P 2015-05-21 2015-05-21
PCT/IB2016/052955 WO2016185428A1 (en) 2015-05-21 2016-05-19 Topical pharmaceutical compositions

Publications (2)

Publication Number Publication Date
MA42111A MA42111A (en) 2018-03-28
MA42111B1 true MA42111B1 (en) 2022-06-30

Family

ID=59714811

Family Applications (1)

Application Number Title Priority Date Filing Date
MA42111A MA42111B1 (en) 2015-05-21 2016-05-19 Topical pharmaceutical compositions

Country Status (2)

Country Link
AR (1) AR104699A1 (en)
MA (1) MA42111B1 (en)

Also Published As

Publication number Publication date
AR104699A1 (en) 2017-08-09
MA42111A (en) 2018-03-28

Similar Documents

Publication Publication Date Title
EA201792559A1 (en) PHARMACEUTICAL COMPOSITIONS FOR LOCAL APPLICATION
EP3695830A4 (en) USE OF A COMPOSITION INCLUDING EXOSOMES DERIVED FROM STEM CELLS AS AN ACTIVE PRINCIPLE FOR STRENGTHENING AND FUNCTIONAL IMPROVEMENT OF THE SKIN BARRIER
FR3041251B1 (en) COMPOSITIONS IN THE FORM OF OIL-IN-WATER EMULSIONS WHOSE FATTY PHASE IS IN THE FORM OF DROPS
MA43918A (en) PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND / OR TREATMENT OF ATOPIC DERMATITIS CONTAINING AN IL-31 ANTAGONIST AS ACTIVE SUBSTANCE
EA201890859A1 (en) PREVENTION, TREATMENT AND TREATMENT OF DEVELOPMENT OF DISEASE WITH THE APPLICATION OF THERAPEUTICALLY EFFECTIVE QUANTITIES OF ACTIVATED FATTY ACIDS
FR2963250B1 (en) WATER-LIKE EMULSION WITHOUT SURFACTANT, PREPARATION METHOD AND USES THEREOF
EP3489252A4 (en) PEPTIDE HAVING ANTI-CANCER ACTIVITY, PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF CANCER, FUNCTIONAL HEALTH FOOD COMPOSITION AND FUNCTIONAL COSMETIC COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT
MA50406B1 (en) Magl pyrazole inhibitors
EP3760626A4 (en) NEW COMPOUND AND COMPOSITION FOR THE PREVENTION, IMPROVEMENT OR TREATMENT OF FIBROSIS OR NON-ALCOHOLIC STEATOHEPATITIS, INCLUDING IT AS AN ACTIVE SUBSTANCE
PH12019500970A1 (en) Composition for the treatment and/or prevention of the black sigatoka fungal disease in banana crops
EP3311817A4 (en) PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING DRY EYE DISEASES CONTAINING IMATINIB AS ACTIVE INGREDIENT
PH12021550865A1 (en) Antiperspirant compositions
EP3610869A4 (en) COMPOSITION CONTAINING SARPOGRELATE AS AN ACTIVE INGREDIENT, FOR THE PREVENTION OR TREATMENT OF NEUROSENSORY HEARING LOSS
FR2967062B1 (en) USE OF POMEGRANATE EXTRACT TO PREVENT AND / OR TREAT PERIOCULAR POUCHES
EP3662907A4 (en) ANTI-AGING OR SKIN REGENERATION COMPOSITION INCLUDING PIPERONYLIC ACID AS ACTIVE INGREDIENT
MA51278A (en) USE OF A PLANT EXTRACT AS AN ACTIVE AGENT IN THE TREATMENT OF DERMATOLOGICAL DISEASES
MA42111B1 (en) Topical pharmaceutical compositions
JP2020519656A5 (en)
EP3973969A4 (en) COMPOSITION FOR THE PREVENTION OR TREATMENT OF CANCER, CONTAINING, AS ACTIVE PRINCIPLE, EXTRACELLULAR VESICLES EXPRESSING IL-2 ON THE SURFACE
MA41102A (en) COMPOSITIONS CONTAINING CURCUMIN WITH ENHANCED BIOAVAILABILITY
EP3741366A4 (en) PHARMACEUTICAL COMPOSITION CONSISTING OF A DUNNIONE AS AN ACTIVE SUBSTANCE FOR THE PREVENTION OR TREATMENT OF HAIR LOSS
EP2543374A4 (en) PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF OSTEOARTHRITIS CONTAINING REBAMIPID AS ACTIVE INGREDIENT
FR3026105B1 (en) COMPOSITION COMPRISING AT LEAST ONE INHIBITOR OF CERTAIN CHEMOKINES, METHOD FOR PRODUCING THE SAME, AND DERMOCOSMETIC OR PHARMACEUTICAL USE THEREOF
EP3878457A4 (en) BROWN/BEIGE ADIPOCYTE ACTIVATOR CONTAINING D-ALLULOSE AS ACTIVE INGREDIENT
EP4205737A4 (en) COMPOSITION FOR THE PREVENTION, IMPROVEMENT OR TREATMENT OF INFLAMMATORY DISEASES OR IMMUNE DISEASES COMPRISING GANCAONIN N AS ACTIVE INGREDIENT