MA42458A - Systèmes améliorés d'administration de nanoparticules - Google Patents

Systèmes améliorés d'administration de nanoparticules

Info

Publication number
MA42458A
MA42458A MA042458A MA42458A MA42458A MA 42458 A MA42458 A MA 42458A MA 042458 A MA042458 A MA 042458A MA 42458 A MA42458 A MA 42458A MA 42458 A MA42458 A MA 42458A
Authority
MA
Morocco
Prior art keywords
delivery systems
nanoparticle delivery
improved nanoparticle
improved
systems
Prior art date
Application number
MA042458A
Other languages
English (en)
Inventor
Winnie Lui
Lawrence Mayer
Paul Tardi
Leon Wan
Original Assignee
Celator Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celator Pharmaceuticals Inc filed Critical Celator Pharmaceuticals Inc
Publication of MA42458A publication Critical patent/MA42458A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA042458A 2015-07-15 2016-07-14 Systèmes améliorés d'administration de nanoparticules MA42458A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562192973P 2015-07-15 2015-07-15
US201562252396P 2015-11-06 2015-11-06

Publications (1)

Publication Number Publication Date
MA42458A true MA42458A (fr) 2018-05-23

Family

ID=57757767

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042458A MA42458A (fr) 2015-07-15 2016-07-14 Systèmes améliorés d'administration de nanoparticules

Country Status (17)

Country Link
US (4) US10285951B2 (fr)
EP (1) EP3322404A4 (fr)
JP (2) JP2018521068A (fr)
KR (1) KR20180029242A (fr)
CN (1) CN107920985B (fr)
AU (2) AU2016294617B2 (fr)
BR (1) BR112018000217A2 (fr)
CA (1) CA2991062C (fr)
CO (1) CO2018000146A2 (fr)
HK (1) HK1251159A1 (fr)
IL (1) IL256797B (fr)
MA (1) MA42458A (fr)
MX (1) MX2018000611A (fr)
RU (1) RU2018105494A (fr)
SG (1) SG10201912394VA (fr)
WO (1) WO2017011685A1 (fr)
ZA (1) ZA201800130B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017190145A1 (fr) 2016-04-29 2017-11-02 Icahn School Of Medicine At Mount Sinai Ciblage du système immunitaire inné pour induire une tolérance à long terme et pour résoudre l'accumulation de macrophages dans l'athérosclérose
JP7357629B2 (ja) * 2017-11-20 2023-10-06 アイカーン スクール オブ メディスン アット マウント サイナイ 治療用ナノバイオロジー組成物での訓練された免疫の阻害
WO2019178443A1 (fr) * 2018-03-16 2019-09-19 University Of Massachusetts Encapsulation de particules de paroi de cellule de levure de procharges utiles biodégradables
KR102088663B1 (ko) * 2018-03-20 2020-03-13 한국세라믹기술원 친수성 및 소수성 약물의 동시 전달을 위한 온도민감성 나노스펀지 플랫폼 및 이의 용도
WO2020123481A1 (fr) * 2018-12-10 2020-06-18 Celator Pharmaceuticals Inc. Formulations combinées de taxanes et d'inhibiteurs de mtor
WO2021030359A1 (fr) * 2019-08-13 2021-02-18 Peptinovo Biopharma, Llc Palm pour le traitement d'une neuropathie périphérique induite par la chimiothérapie incidente au traitement du cancer
CN118286450A (zh) * 2019-11-12 2024-07-05 纳米医疗有限公司 用于治疗癌症的含有ido拮抗剂前药的调配的和/或共同调配的脂质体组合物及其方法
US11833209B2 (en) * 2020-09-11 2023-12-05 Nammi Therapeutics, Inc. Formulated and/or co-formulated liposome compositions containing PD-1 antagonist prodrugs useful in the treatment of cancer and methods thereof
CN118459539B (zh) 2021-03-19 2026-01-06 生物治疗探索股份有限公司 用于调节训练免疫的化合物及其使用方法
WO2025199353A1 (fr) * 2024-03-21 2025-09-25 Purdue Research Foundation Formulations nanoparticulaires et leur administration foliaire dans le traitement et la prévention de la maladie du dragon jaune

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1432402E (pt) * 2001-10-03 2007-02-28 Celator Pharmaceuticals Inc Composições para administração de combinações de fármacos
US20030118528A1 (en) 2001-11-19 2003-06-26 Walters Kenneth A. Topical delivery of codrugs
JP2006514088A (ja) 2003-02-20 2006-04-27 ユニバーシティー オブ コネティカット ヘルス センター 癌および感染症の治療における熱ショックタンパク質またはα−2−マクログロブリンを含む組成物の使用方法
IL180785A (en) 2004-07-19 2014-03-31 Celator Pharmaceuticals Inc Preparations containing particulate structures for the release of active substances
WO2006110862A2 (fr) * 2005-04-12 2006-10-19 Wisconsin Alumni Research Foundation Composition micellaire polymere et medicament contenu dans celle-ci
CN101878024B (zh) * 2007-11-28 2014-04-09 塞拉特药物股份有限公司 改良的紫杉烷递送系统
BRPI1014854A2 (pt) * 2009-03-30 2016-05-03 Cerulean Pharma Inc "conjugados polímero-agente, partículas, composições, e métodos de uso relacionados"
US20110118298A1 (en) * 2009-11-13 2011-05-19 Infinity Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer
EP2605797A2 (fr) * 2010-08-20 2013-06-26 Cerulean Pharma Inc. Conjugués peptide thérapeutique-polymère, particules, compositions et procédés apparentés
CN104689318A (zh) * 2010-11-19 2015-06-10 葛兰素史密斯克莱知识产权(第2号)有限公司 使用braf抑制剂的治疗方法
CN107320734A (zh) * 2011-04-29 2017-11-07 西莱克塔生物科技公司 从合成纳米载体中控制释放免疫抑制剂
US20140308363A1 (en) * 2011-05-31 2014-10-16 Bind Therapeutics, Inc. Drug loaded polymeric nanoparticles and methods of making and using same
DE102011109374A1 (de) * 2011-08-04 2013-02-07 Bock 1 Gmbh & Co. Kg Stuhl mit Wippmechanik
CN110478495A (zh) * 2014-06-30 2019-11-22 塔弗达治疗有限公司 靶向缀合物及其颗粒和制剂

Also Published As

Publication number Publication date
RU2018105494A3 (fr) 2019-12-17
AU2016294617B2 (en) 2021-09-16
JP2018521068A (ja) 2018-08-02
BR112018000217A2 (pt) 2018-09-04
KR20180029242A (ko) 2018-03-20
US20190209484A1 (en) 2019-07-11
CN107920985B (zh) 2022-03-01
US10285951B2 (en) 2019-05-14
US20240366519A1 (en) 2024-11-07
US20210052508A1 (en) 2021-02-25
US20180207104A1 (en) 2018-07-26
ZA201800130B (en) 2018-12-19
JP2022033751A (ja) 2022-03-02
US11413253B2 (en) 2022-08-16
EP3322404A1 (fr) 2018-05-23
SG10201912394VA (en) 2020-02-27
EP3322404A4 (fr) 2019-03-20
CO2018000146A2 (es) 2018-04-19
IL256797B (en) 2021-05-31
IL256797A (en) 2018-06-28
AU2021286353A1 (en) 2022-01-20
WO2017011685A1 (fr) 2017-01-19
HK1251159A1 (zh) 2019-01-25
CA2991062A1 (fr) 2017-01-19
CN107920985A (zh) 2018-04-17
MX2018000611A (es) 2018-09-06
AU2016294617A1 (en) 2018-01-25
CA2991062C (fr) 2023-06-20
RU2018105494A (ru) 2019-08-15

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