MA42818A - Modulateurs de récepteurs de type toll pour le traitement du vih - Google Patents
Modulateurs de récepteurs de type toll pour le traitement du vihInfo
- Publication number
- MA42818A MA42818A MA042818A MA42818A MA42818A MA 42818 A MA42818 A MA 42818A MA 042818 A MA042818 A MA 042818A MA 42818 A MA42818 A MA 42818A MA 42818 A MA42818 A MA 42818A
- Authority
- MA
- Morocco
- Prior art keywords
- toll
- receptor modulators
- type receptor
- hiv treatment
- hiv
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562218858P | 2015-09-15 | 2015-09-15 | |
| US201662382550P | 2016-09-01 | 2016-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA42818A true MA42818A (fr) | 2018-07-25 |
Family
ID=56997570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA042818A MA42818A (fr) | 2015-09-15 | 2016-09-13 | Modulateurs de récepteurs de type toll pour le traitement du vih |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20180263985A1 (fr) |
| EP (1) | EP3349757A1 (fr) |
| JP (1) | JP2018527366A (fr) |
| AU (1) | AU2016322763A1 (fr) |
| CA (1) | CA2997955A1 (fr) |
| HK (1) | HK1257270A1 (fr) |
| MA (1) | MA42818A (fr) |
| WO (1) | WO2017048727A1 (fr) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008009078A2 (fr) | 2006-07-20 | 2008-01-24 | Gilead Sciences, Inc. | Dérivés de la quinazoline tri-substitués en 4,6-dl et en 2,4,6 utilisables pour traiter les infections virales |
| WO2016106050A1 (fr) | 2014-12-26 | 2016-06-30 | Emory University | N4-hydroxycytidine, ses dérivés et utilisations anti-virales |
| SG11201606876RA (en) | 2015-03-04 | 2016-10-28 | Gilead Sciences Inc | Toll like receptor modulator compounds |
| WO2018045150A1 (fr) * | 2016-09-02 | 2018-03-08 | Gilead Sciences, Inc. | Dérivés de 4,6-diamino-pyrido [3,2-d] pyrimidine en tant que modulateurs du récepteur de type toll |
| SI3507276T1 (sl) | 2016-09-02 | 2022-01-31 | Gilead Sciences, Inc. | Spojine modulatorja toličnih receptorjev |
| FR3066761B1 (fr) * | 2017-05-23 | 2020-10-30 | Centre Nat Rech Scient | Nouveaux composes inhibiteurs des canaux ioniques |
| CN108069963B (zh) * | 2017-11-17 | 2020-01-14 | 清华大学 | 吡啶并嘧啶衍生物或其盐及其制法、药物组合物和用途 |
| RU2020116571A (ru) | 2017-12-07 | 2021-11-22 | Эмори Юниверсити | N4-гидроксицитидин и производные и связанные с этим противовирусные применения |
| WO2019195181A1 (fr) | 2018-04-05 | 2019-10-10 | Gilead Sciences, Inc. | Anticorps et leurs fragments qui se lient à la protéine x du virus de l'hépatite b |
| BR112020026890A2 (pt) * | 2018-07-03 | 2021-03-30 | Jiangsu Hengrui Medicine Co., Ltd. | Derivado de piridopirimidina, método de preparação do mesmo e uso médico do mesmo |
| SG11202101980VA (en) | 2018-09-12 | 2021-03-30 | Silverback Therapeutics Inc | Methods and composition for the treatment of disease with immune stimulatory conjugates |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| KR20240151256A (ko) | 2019-03-22 | 2024-10-17 | 길리애드 사이언시즈, 인코포레이티드 | 가교된 트리시클릭 카르바모일피리돈 화합물 및 그의 제약 용도 |
| TW202210480A (zh) * | 2019-04-17 | 2022-03-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TWI751517B (zh) * | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TWI879779B (zh) | 2019-06-28 | 2025-04-11 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
| AU2020315598B2 (en) * | 2019-07-16 | 2024-12-12 | Gilead Sciences, Inc. | HIV vaccines and methods of making and using |
| JP2022545872A (ja) * | 2019-08-19 | 2022-11-01 | シャンハイ ジムン バイオファーマ，インコーポレーテッド | ２―アミノピリミジン化合物ならびにその医薬組成物および用途 |
| HRP20241379T1 (hr) | 2019-09-30 | 2024-12-20 | Gilead Sciences, Inc. | Cjepiva za hbv i postupci za liječenje hbv |
| WO2021067644A1 (fr) | 2019-10-01 | 2021-04-08 | Silverback Therapeutics, Inc. | Polythérapie comprenant des conjugués immunostimulants |
| EP3821890A1 (fr) * | 2019-11-18 | 2021-05-19 | Strumberg, Dirk | Compositions pharmaceutiques comprenant un inhibiteur de l'histone désacétylase (hdaci) et un agoniste de récepteur de type toll 7 et/ou 8 (tlr7 et/ou tlr8) et leur utilisation dans le traitement du cancer |
| US12410418B2 (en) | 2019-12-06 | 2025-09-09 | Precision Biosciences, Inc. | Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome |
| AU2020416484A1 (en) * | 2020-01-02 | 2022-08-25 | Jiangsu Hengrui Medicine Co., Ltd. | Crystal form of pyridopyrimidine derivative and preparation method thereof |
| US11179473B2 (en) | 2020-02-21 | 2021-11-23 | Silverback Therapeutics, Inc. | Nectin-4 antibody conjugates and uses thereof |
| KR102987126B1 (ko) | 2020-03-20 | 2026-07-07 | 길리애드 사이언시즈, 인코포레이티드 | 4'-c-치환된-2-할로-2'-데옥시아데노신 뉴클레오시드의 프로드러그 및 이의 제조 및 사용 방법 |
| KR20230047361A (ko) | 2020-07-01 | 2023-04-07 | 아르스 파마슈티컬스 인크. | 항-asgr1 항체 접합체 및 이의 용도 |
| TWI815194B (zh) | 2020-10-22 | 2023-09-11 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| CN116437958A (zh) | 2020-11-11 | 2023-07-14 | 吉利德科学公司 | 鉴定对采用gp120 CD4结合位点导向的抗体的疗法敏感的HIV患者的方法 |
| CA3202466A1 (fr) | 2021-01-14 | 2022-07-21 | Jiani LI | Vaccins contre le vih et methodes d'utilisation |
| US20240269142A1 (en) | 2021-05-13 | 2024-08-15 | Gilead Sciences, Inc. | COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS |
| MX2023014762A (es) | 2021-06-23 | 2024-01-15 | Gilead Sciences Inc | Compuestos moduladores de diacilglicerol quinasa. |
| EP4359413A1 (fr) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Composés de modulation de la diacylglycérol kinase |
| JP7651018B2 (ja) | 2021-06-23 | 2025-03-25 | ギリアード サイエンシーズ， インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 |
| FI4440702T3 (fi) | 2021-12-03 | 2025-08-08 | Gilead Sciences Inc | Terapeuttisia yhdisteitä hiv-virusinfektiota varten |
| AU2022399845B2 (en) | 2021-12-03 | 2026-03-26 | Gilead Sciences, Inc. | Therapeutic compounds for hiv virus infection |
| AU2022403012B2 (en) | 2021-12-03 | 2026-02-12 | Gilead Sciences, Inc. | Therapeutic compounds for hiv virus infection |
| TWI856796B (zh) | 2022-04-06 | 2024-09-21 | 美商基利科學股份有限公司 | 橋聯三環胺甲醯基吡啶酮化合物及其用途 |
| US20240034724A1 (en) | 2022-07-01 | 2024-02-01 | Gilead Sciences, Inc. | Therapeutic compounds useful for the prophylactic or therapeutic treatment of an hiv virus infection |
| CN119768183A (zh) | 2022-08-26 | 2025-04-04 | 吉利德科学公司 | 用于广泛中和抗体的给药和安排方案 |
| WO2024076915A1 (fr) | 2022-10-04 | 2024-04-11 | Gilead Sciences, Inc. | Analogues de 4'-thionucléosides et leur utilisation pharmaceutique |
| EP4698174A1 (fr) | 2023-04-19 | 2026-02-25 | Gilead Sciences, Inc. | Schéma posologique d'inhibiteur de capside |
| WO2024249573A1 (fr) | 2023-05-31 | 2024-12-05 | Gilead Sciences, Inc. | Formes solides de composés utiles dans le traitement du vih |
| TW202448483A (zh) | 2023-05-31 | 2024-12-16 | 美商基利科學股份有限公司 | 用於ｈｉｖ之治療性化合物 |
| CN122295099A (zh) | 2023-07-28 | 2026-06-26 | 吉利德科学公司 | 用于治疗和预防hiv的来那卡帕韦的每周方案 |
| AU2023462614A1 (en) | 2023-08-23 | 2026-03-19 | Gilead Sciences, Inc. | Dosing regimen of hiv capsid inhibitor |
| AU2024360779A1 (en) | 2023-10-11 | 2026-04-16 | Gilead Sciences, Inc. | Bridged tricyclic carbamoylpyridone compounds and uses thereof |
| IL327206A (en) | 2023-10-11 | 2026-05-01 | Gilead Sciences Inc | Bridged tricyclic carbamoylpyridone compounds and their uses |
| KR20260093341A (ko) | 2023-10-11 | 2026-06-19 | 길리애드 사이언시즈, 인코포레이티드 | 가교 트리시클릭 카르바모일피리돈 화합물 및 이의 용도 |
| WO2025137245A1 (fr) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Formes solides d'inhibiteurs de l'intégrase du vih |
| US20250333424A1 (en) | 2024-03-01 | 2025-10-30 | Gilead Sciences, Inc. | Antiviral compounds |
| WO2025184447A1 (fr) | 2024-03-01 | 2025-09-04 | Gilead Sciences, Inc. | Compositions pharmaceutiques comprenant des inhibiteurs de l'intégrase du vih |
| WO2025184452A1 (fr) | 2024-03-01 | 2025-09-04 | Gilead Sciences, Inc. | Formes solides d'inhibiteurs de l'intégrase du vih |
| TW202608468A (zh) | 2024-05-13 | 2026-03-01 | 美商基利科學股份有限公司 | 組合療法 |
| WO2025240246A1 (fr) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Polythérapies avec de la ribavirine |
| US20250345390A1 (en) | 2024-05-13 | 2025-11-13 | Gilead Sciences, Inc. | Combination therapies |
| WO2025240242A1 (fr) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Polythérapies avec ribavirine |
| WO2025260028A1 (fr) | 2024-06-14 | 2025-12-18 | Gilead Sciences, Inc. | Compositions pharmaceutiques comprenant des inhibiteurs de l'intégrase du vih |
| WO2026076265A1 (fr) | 2024-10-03 | 2026-04-09 | Gilead Sciences, Inc. | Thérapie de combinaison comprenant des composés de carbamoylpyridone tricycliques pontés et des inhibiteurs de la p-glycoprotéine |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4724232A (en) | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
| CS263952B1 (en) | 1985-04-25 | 1989-05-12 | Holy Antonin | Remedy with antiviral effect |
| WO1987001284A1 (fr) | 1985-08-26 | 1987-03-12 | United States Of America, Represented By The Unite | Inhibition du caractere infectieux et de l'effet cytopathique du htlv-iii/lav in vitro par la 2',3'-dideoxyinosine, 2',3'-dideoxyguanosine, ou 2',3'-dideoxyadenosine |
| US6492352B1 (en) | 1985-10-31 | 2002-12-10 | Astra Lakemedel Aktiebolag | Method for the control and treatment of acquired immunodeficiency syndrome (AIDS) |
| US4978655A (en) | 1986-12-17 | 1990-12-18 | Yale University | Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses |
| US5028595A (en) | 1987-09-18 | 1991-07-02 | Hoffmann-La Roche Inc. | Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus |
| US5047407A (en) | 1989-02-08 | 1991-09-10 | Iaf Biochem International, Inc. | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties |
| GB8815265D0 (en) | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
| US5366972A (en) | 1989-04-20 | 1994-11-22 | Boehringer Ingelheim Pharmaceuticals, Inc. | 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection |
| US5696270A (en) | 1989-05-23 | 1997-12-09 | Abbott Laboratories | Intermediate for making retroviral protease inhibiting compounds |
| GB8927913D0 (en) | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Amino acid derivatives |
| US5563142A (en) | 1989-12-28 | 1996-10-08 | The Upjohn Company | Diaromatic substituted compounds as anti-HIV-1 agents |
| US6642245B1 (en) | 1990-02-01 | 2003-11-04 | Emory University | Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane |
| US5204466A (en) | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
| US5413999A (en) | 1991-11-08 | 1995-05-09 | Merck & Co., Inc. | HIV protease inhibitors useful for the treatment of AIDS |
| US5663169A (en) | 1992-08-07 | 1997-09-02 | Merck & Co., Inc. | Benzoxazinones as inhibitors of HIV reverse transcriptase |
| US5484926A (en) | 1993-10-07 | 1996-01-16 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| US5646180A (en) | 1995-12-05 | 1997-07-08 | Vertex Pharmaceuticals Incorporated | Treatment of the CNS effects of HIV |
| US5849911A (en) | 1996-04-22 | 1998-12-15 | Novartis Finance Corporation | Antivirally active heterocyclic azahexane derivatives |
| US6436989B1 (en) | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
| AU2005285513B2 (en) | 2004-05-25 | 2011-02-24 | Oregon Health And Science University | SIV and HIV vaccination using RhCMV- and HCMV-based vaccine vectors |
| EP1877090B1 (fr) | 2005-05-06 | 2014-01-15 | Providence Health System | Proteine de fusion trimere immunoglobulinique ox-40 et procedes d'utilisation |
| WO2006135993A1 (fr) * | 2005-06-24 | 2006-12-28 | Gilead Sciences, Inc. | Pyrido(3,2-d)pyrimidines et compositions pharmaceutiques destinees au traitement de l'hepatite c |
| TWI382019B (zh) | 2005-08-19 | 2013-01-11 | Array Biopharma Inc | 作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之胺基二氮雜呯 |
| TW201402124A (zh) * | 2005-08-19 | 2014-01-16 | Array Biopharma Inc | 作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之８-經取代苯并氮雜呯 |
| TW200840584A (en) * | 2006-12-26 | 2008-10-16 | Gilead Sciences Inc | Pyrido(3,2-d)pyrimidines useful for treating viral infections |
| US8143394B2 (en) * | 2006-12-26 | 2012-03-27 | Gilead Sciences, Inc. | Pyrido(3,2-d)pyrimidines useful for treating viral infections |
| US8354429B2 (en) | 2007-11-16 | 2013-01-15 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| SI2242771T1 (sl) | 2007-12-14 | 2013-09-30 | Bristol-Myers Squibb Company | Vezane molekule k humanemu ox40 receptorju |
| CA2732437C (fr) | 2008-08-01 | 2017-11-21 | Ventirx Pharmaceuticals, Inc. | Formulations d'agoniste des recepteurs de type toll et leur utilisation |
| SI3260136T1 (sl) | 2009-03-17 | 2021-05-31 | Theraclone Sciences, Inc. | Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa |
| US8338441B2 (en) | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| CN105669552A (zh) | 2009-08-18 | 2016-06-15 | 文蒂雷克斯药品公司 | 作为toll样受体调节剂的取代的苯并氮杂* |
| CN105669553A (zh) | 2009-08-18 | 2016-06-15 | 文蒂雷克斯药品公司 | 作为toll样受体调节剂的取代的苯并氮杂* |
| US20110305670A1 (en) | 2010-06-10 | 2011-12-15 | President And Fellows Of Harvard College | Nucleic acid encoding fusion polypeptides that prevent or inhibit hiv infection |
| EP2588455B1 (fr) | 2010-07-02 | 2018-04-04 | Gilead Sciences, Inc. | Dérivés de l'acide 2-quinolinyl-acétique en tant que composés antiviraux hiv |
| CN103140474A (zh) | 2010-07-02 | 2013-06-05 | 吉里德科学公司 | 治疗aids的萘-2-基乙酸衍生物 |
| CA3201524C (fr) | 2010-08-31 | 2026-01-13 | International Aids Vaccine Initiative | Anticorps neutralisants anti-virus de l'immunodeficience humaine (vih) |
| KR101866893B1 (ko) | 2010-10-01 | 2018-06-14 | 벤티알엑스 파마슈티칼스 인코포레이티드 | Tlr 아고니스트의 치료적 용도 및 병용 요법 |
| US20120082658A1 (en) | 2010-10-01 | 2012-04-05 | Ventirx Pharmaceuticals, Inc. | Methods for the Treatment of Allergic Diseases |
| WO2012064973A2 (fr) * | 2010-11-10 | 2012-05-18 | Infinity Pharmaceuticals, Inc. | Composés hétérocycliques et utilisations de ceux-ci |
| MX346387B (es) | 2011-01-12 | 2017-03-02 | Ventirx Pharmaceuticals Inc | Benzoazepinas sustituidas como moduladores de receptores tipo toll. |
| ES2691745T3 (es) | 2011-04-08 | 2018-11-28 | Janssen Sciences Ireland Uc | Derivados de pirimidina para el tratamiento de infecciones víricas |
| CN104271740A (zh) | 2011-04-20 | 2015-01-07 | L·J·史密斯 | 利用在细胞中自组装和产生RNAi活性的成分来调节基因表达的方法和组合物 |
| MX2013012266A (es) | 2011-04-21 | 2013-11-22 | Gilead Sciences Inc | Compuestos de benzotiazol y su uso farmaceutico. |
| PL2709989T3 (pl) * | 2011-05-18 | 2018-06-29 | Janssen Sciences Ireland Uc | Pochodne chinazoliny do leczenia infekcji wirusowych i dalszych chorób |
| EP2734520B1 (fr) * | 2011-07-19 | 2016-09-14 | Infinity Pharmaceuticals, Inc. | Composés hétérocycliques et leurs utilisations |
| EA039373B1 (ru) * | 2012-02-08 | 2022-01-19 | Янссен Сайенсиз Айрлэнд Юси | Производные пиперидино-пиримидина для лечения вирусных инфекций |
| ES2571479T3 (es) | 2012-04-20 | 2016-05-25 | Gilead Sciences Inc | Derivados del ácido benzotiazol-6-il acético y su uso para tratar una infección por VIH |
| WO2013163427A1 (fr) | 2012-04-25 | 2013-10-31 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Anticorps pour traiter les infections par le vih-1 |
| JP6302906B2 (ja) | 2012-08-10 | 2018-03-28 | ヤンセン・サイエンシズ・アイルランド・ユーシー | ウイルス感染および他の疾患を治療するためのアルキルピリミジン誘導体 |
| MX386924B (es) | 2012-10-10 | 2025-03-19 | Janssen Sciences Ireland Uc | Derivados pirrolo[3,2-d]pirimidínicos para el tratamiento de infecciones víricas y otras enfermedades. |
| US9663474B2 (en) | 2012-11-16 | 2017-05-30 | Janssen Sciences Ireland Uc | Heterocyclic substituted 2-amino quinazoline derivatives for the treatment of viral infections |
| KR102300861B1 (ko) | 2013-02-21 | 2021-09-10 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 바이러스 감염의 치료를 위한 2-아미노피리미딘 유도체 |
| NO2865735T3 (fr) | 2013-07-12 | 2018-07-21 | ||
| DK3019503T3 (da) | 2013-07-12 | 2017-11-20 | Gilead Sciences Inc | Polycykliske-carbamoylpyridon-forbindelser og anvendelse deraf til behandling af hiv-infektioner |
| SG11201606876RA (en) * | 2015-03-04 | 2016-10-28 | Gilead Sciences Inc | Toll like receptor modulator compounds |
-
2016
- 2016-09-13 US US15/759,177 patent/US20180263985A1/en not_active Abandoned
- 2016-09-13 MA MA042818A patent/MA42818A/fr unknown
- 2016-09-13 WO PCT/US2016/051545 patent/WO2017048727A1/fr not_active Ceased
- 2016-09-13 US US15/264,401 patent/US20170071944A1/en not_active Abandoned
- 2016-09-13 JP JP2018513529A patent/JP2018527366A/ja active Pending
- 2016-09-13 HK HK18116414.4A patent/HK1257270A1/zh unknown
- 2016-09-13 AU AU2016322763A patent/AU2016322763A1/en not_active Abandoned
- 2016-09-13 CA CA2997955A patent/CA2997955A1/fr not_active Abandoned
- 2016-09-13 EP EP16770854.4A patent/EP3349757A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP3349757A1 (fr) | 2018-07-25 |
| CA2997955A1 (fr) | 2017-03-23 |
| WO2017048727A1 (fr) | 2017-03-23 |
| JP2018527366A (ja) | 2018-09-20 |
| US20170071944A1 (en) | 2017-03-16 |
| US20180263985A1 (en) | 2018-09-20 |
| AU2016322763A1 (en) | 2018-04-19 |
| HK1257270A1 (zh) | 2019-10-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA47719A (fr) | Esketamine pour le traitement de la dépression | |
| MA47501A (fr) | Dérivé de di-nucléotides cycliques pour le traitement du cancer | |
| EP3364904A4 (fr) | Balayage variable pour dispositifs d'entrée | |
| EP3488338A4 (fr) | Technologies pour le traitement adaptatif de tampons multiples | |
| EP3277465A4 (fr) | Mécanisme de levage pour cloueuse de charpente | |
| MA48448A (fr) | Dérivés de quinazoline utilisés pour traiter le vih | |
| EP3351189A4 (fr) | Instrument de traitement pour endoscope | |
| EP3482506A4 (fr) | Relaxation de traitement pour csi-rs apériodiques | |
| EP3388004A4 (fr) | Instrument de traitement | |
| MA43382A (fr) | Modulateurs des récepteurs des chimiokines | |
| MA41449A (fr) | Polythérapies pour le traitement de cancers | |
| EP3374502A4 (fr) | Procédés pour le traitement de dystrophies cornéennes | |
| EP3630078A4 (fr) | Agents pour chimio-embolisation | |
| MA39748A (fr) | Cenicriviroc pour le traitement de la fibrose | |
| EP3621592A4 (fr) | Polythérapies pour le traitement du cancer | |
| EP3362065A4 (fr) | Polythérapie pour le traitement de malignités | |
| DK3359160T3 (da) | Farnesoid x receptor modulatorer | |
| EP3353866A4 (fr) | Appareil pour le cheminement de câbles | |
| FR3036518B1 (fr) | Inversion pour contrainte tectonique | |
| EP3335041A4 (fr) | Biomarqueurs pour le traitement de la pelade | |
| EP3690324A4 (fr) | Système de traitement de fumée pour sauteuse et sauteuse | |
| EP3389645A4 (fr) | Combinaisons pour le traitement du cancer | |
| EP3383407A4 (fr) | Conjugués de cytarabine pour le traitement du cancer | |
| EP3395291A4 (fr) | Dispositif de suspension pour instrument dentaire | |
| FR3042807B1 (fr) | Autolestage pour banche de coffrage |