MA42915A - Pyridines et leur utilisation dans le traitement du cancer - Google Patents

Pyridines et leur utilisation dans le traitement du cancer

Info

Publication number
MA42915A
MA42915A MA042915A MA42915A MA42915A MA 42915 A MA42915 A MA 42915A MA 042915 A MA042915 A MA 042915A MA 42915 A MA42915 A MA 42915A MA 42915 A MA42915 A MA 42915A
Authority
MA
Morocco
Prior art keywords
pyridines
cancer treatment
cancer
treatment
Prior art date
Application number
MA042915A
Other languages
English (en)
Inventor
Elias Set Jenö Arnér
Nathan Patrick Coussens
Thomas S Dexheimer
Ajit Jadhav
Diane Karen Luci
David Joseph Maloney
Anton Simeonov
William Chester Stafford
Original Assignee
Arner Elias Set Jenoe
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arner Elias Set Jenoe, Us Health filed Critical Arner Elias Set Jenoe
Publication of MA42915A publication Critical patent/MA42915A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA042915A 2015-08-07 2016-08-05 Pyridines et leur utilisation dans le traitement du cancer MA42915A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1514021.3A GB201514021D0 (en) 2015-08-07 2015-08-07 Novel Pyridines and their use in the treatment of cancer

Publications (1)

Publication Number Publication Date
MA42915A true MA42915A (fr) 2018-08-01

Family

ID=54200423

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042915A MA42915A (fr) 2015-08-07 2016-08-05 Pyridines et leur utilisation dans le traitement du cancer

Country Status (12)

Country Link
US (1) US10899710B2 (fr)
EP (1) EP3331858A1 (fr)
JP (1) JP6636153B2 (fr)
KR (1) KR102180934B1 (fr)
CN (1) CN108026044A (fr)
AU (1) AU2016306276B2 (fr)
CA (1) CA2995077C (fr)
GB (1) GB201514021D0 (fr)
MA (1) MA42915A (fr)
MX (1) MX391999B (fr)
RU (1) RU2730505C2 (fr)
WO (1) WO2017027359A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201514021D0 (en) 2015-08-07 2015-09-23 Arner Elias Set Jeno Novel Pyridines and their use in the treatment of cancer
CR20180596A (es) 2016-05-24 2019-04-09 Basf Se Uracilpiridinas herbicidas
MX392900B (es) * 2017-02-07 2025-03-24 Oblique Therapeutics Ab Piridinas sustituidas con hidrocarbilsulfonilo y su uso en el tratamiento del cancer
KR20190115013A (ko) 2017-02-07 2019-10-10 오블리크 세러퓨틱스 에이비 헤테로아릴설포닐-치환된 피리딘 및 암의 치료에서 이의 용도
JP2020507624A (ja) 2017-02-07 2020-03-12 オブリーク セラピューティクス アーベー スルフィニルピリジンおよび癌の治療におけるそれらの使用
WO2018146471A1 (fr) 2017-02-07 2018-08-16 Oblique Therapeutics Ab Pyridines à substitution hétérocyclylsulfonyle et leur utilisation dans le traitement du cancer
AU2019219322A1 (en) * 2018-02-12 2020-09-10 Cinda Pharma Ab Thioredoxin reductase inhibitors for use in the treatment of cancer
WO2020219668A1 (fr) * 2019-04-24 2020-10-29 Memorial Sloan Kettering Cancer Center Compositions et méthodes de traitement de cancers à mutation de ras

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ATE4643T1 (de) 1979-12-19 1983-09-15 Duphar International Research B.V Nitrothiophene, verfahren zur herstellung der verbindungen sowie fungizide und/oder bakterizide zusammensetzungen auf der basis dieser verbindungen.
AU543161B2 (en) 1980-03-07 1985-04-04 E.I. Du Pont De Nemours And Company Pyrimidine or s.triazine derivatives
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DE3812177A1 (de) 1988-04-13 1989-10-26 Bayer Ag 2-phenylsulfinyl-nitro-pyridine, verfahren zu ihrer herstellung und ihre verwendung
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DE19531148A1 (de) 1995-08-24 1997-02-27 Basf Ag Fungizide Pyridin-2-yl-Derivate
US6069144A (en) 1995-08-24 2000-05-30 Basf Aktiengesellschaft N-heterocyclic compounds, intermediate products used to prepare them, agents containing them and their use in antifungal applications
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SI0930302T1 (en) * 1998-01-16 2003-10-31 F. Hoffmann-La Roche Ag Benzosulfone derivatives
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JP6393322B2 (ja) * 2013-07-10 2018-09-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なキラル窒素−リン配位子及びアルケン類の不斉水素化のためのその使用
CN104672214B (zh) 2013-12-03 2019-04-12 上海翰森生物医药科技有限公司 具有alk抑制活性的化合物及其制备与用途
CN105503827B (zh) 2014-10-11 2019-09-24 上海翰森生物医药科技有限公司 Egfr抑制剂及其制备方法和用途
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GB201514021D0 (en) 2015-08-07 2015-09-23 Arner Elias Set Jeno Novel Pyridines and their use in the treatment of cancer
MX392900B (es) 2017-02-07 2025-03-24 Oblique Therapeutics Ab Piridinas sustituidas con hidrocarbilsulfonilo y su uso en el tratamiento del cancer
JP2020507624A (ja) 2017-02-07 2020-03-12 オブリーク セラピューティクス アーベー スルフィニルピリジンおよび癌の治療におけるそれらの使用
KR20190115013A (ko) 2017-02-07 2019-10-10 오블리크 세러퓨틱스 에이비 헤테로아릴설포닐-치환된 피리딘 및 암의 치료에서 이의 용도
WO2018146471A1 (fr) 2017-02-07 2018-08-16 Oblique Therapeutics Ab Pyridines à substitution hétérocyclylsulfonyle et leur utilisation dans le traitement du cancer

Also Published As

Publication number Publication date
CA2995077C (fr) 2020-04-21
RU2730505C2 (ru) 2020-08-24
WO2017027359A1 (fr) 2017-02-16
CA2995077A1 (fr) 2017-02-16
GB201514021D0 (en) 2015-09-23
KR102180934B1 (ko) 2020-11-20
US20200087260A1 (en) 2020-03-19
MX391999B (es) 2025-03-21
KR20180035904A (ko) 2018-04-06
RU2018107879A3 (fr) 2019-09-09
EP3331858A1 (fr) 2018-06-13
US10899710B2 (en) 2021-01-26
JP2018525443A (ja) 2018-09-06
AU2016306276A1 (en) 2018-02-22
CN108026044A (zh) 2018-05-11
WO2017027359A8 (fr) 2017-04-20
RU2018107879A (ru) 2019-09-09
AU2016306276B2 (en) 2019-08-01
MX2018001576A (es) 2018-11-09
JP6636153B2 (ja) 2020-01-29

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