MA43183A - Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé - Google Patents

Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé

Info

Publication number
MA43183A
MA43183A MA043183A MA43183A MA43183A MA 43183 A MA43183 A MA 43183A MA 043183 A MA043183 A MA 043183A MA 43183 A MA43183 A MA 43183A MA 43183 A MA43183 A MA 43183A
Authority
MA
Morocco
Prior art keywords
gemcitabine
therapeutic agent
agent containing
composition based
liposomal composition
Prior art date
Application number
MA043183A
Other languages
English (en)
Inventor
Tsukasa KITAHASHI
Takeshi Matsumoto
Shinji Mima
Mikinaga Mori
Takahiro Sekiguchi
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of MA43183A publication Critical patent/MA43183A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MA043183A 2015-11-02 2016-11-01 Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé MA43183A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015215768 2015-11-02

Publications (1)

Publication Number Publication Date
MA43183A true MA43183A (fr) 2018-09-12

Family

ID=58662534

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043183A MA43183A (fr) 2015-11-02 2016-11-01 Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé

Country Status (11)

Country Link
US (3) US11166913B2 (fr)
EP (1) EP3372232B1 (fr)
JP (1) JP6602886B2 (fr)
KR (1) KR102084340B1 (fr)
CN (3) CN111437259A (fr)
DK (1) DK3372232T3 (fr)
ES (1) ES2869283T3 (fr)
MA (1) MA43183A (fr)
PL (1) PL3372232T3 (fr)
RU (3) RU2768178C2 (fr)
WO (1) WO2017078008A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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SI3138555T1 (sl) 2014-04-30 2021-06-30 Fujifilm Corporation Liposomski sestavek in proizvodni postopek zanj
JP6602886B2 (ja) 2015-11-02 2019-11-06 富士フイルム株式会社 ゲムシタビンリポソーム組成物を含む腫瘍治療剤およびキット
RU2734900C1 (ru) 2017-03-31 2020-10-26 Фуджифилм Корпорэйшн Липосомальная композиция и фармацевтическая композиция
JP7036919B2 (ja) * 2018-06-20 2022-03-15 富士フイルム株式会社 薬物を内包するリポソーム組成物および免疫チェックポイント阻害剤を含む組合せ医薬
AU2019288048B2 (en) * 2018-06-20 2022-08-11 Fujifilm Corporation Combined medicine comprising gemcitabine-encapsulated liposome composition and immune checkpoint blockade
EP3861987A4 (fr) * 2018-10-01 2021-09-15 FUJIFILM Corporation Médicament combiné comprenant une composition de liposome encapsulant un médicament et préparation à base de platine
CN112898277B (zh) * 2019-11-19 2022-04-22 扬子江药业集团有限公司 一种阿法替尼中间体的制备方法
CN111035616B (zh) * 2019-12-30 2022-03-22 上海景峰制药有限公司 一种吉西他滨脂质体及其制备方法和应用
FI4129304T3 (fi) * 2020-04-03 2024-11-27 Fujifilm Corp Kasvainvastainen aine
US20250152615A1 (en) * 2022-03-25 2025-05-15 Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. Gemcitabine liposome pharmaceutical composition, preparation method therefor and use thereof
WO2023186923A1 (fr) 2022-03-30 2023-10-05 Meta Materials Inc. Système implanté d'administration d'agent
TW202535424A (zh) * 2023-10-31 2025-09-16 日商富士軟片股份有限公司 脂質體組成物的製造方法及脂質體組成物

Family Cites Families (27)

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US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
WO2004017944A1 (fr) * 2002-08-23 2004-03-04 Neopharm, Inc. Compositions de gemcitabine pour une administration de medicaments amelioree
EP1643971A2 (fr) * 2003-05-22 2006-04-12 Neopharm, Inc. Formulations liposomales combinees
WO2005021012A1 (fr) * 2003-08-29 2005-03-10 Terumo Kabushiki Kaisha Vecteur de medicament contenant de la gemcitabine
CA2821167C (fr) 2004-05-03 2016-06-28 Merrimack Pharmaceuticals, Inc. Liposomes pour l'administration de drogues contenant des polyols anioniques ou des sucres anioniques
US20070014845A1 (en) * 2005-07-01 2007-01-18 Yuanpeng Zhang Liposomal delivery vehicle for hydrophobic drugs
AU2006321796A1 (en) * 2005-12-08 2007-06-14 Wyeth Liposomal compositions
US8119156B2 (en) * 2006-10-24 2012-02-21 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
CN101209243B (zh) 2006-12-29 2010-12-08 石药集团中奇制药技术(石家庄)有限公司 一种脂质体药物及其制备方法
CN100496609C (zh) * 2006-12-30 2009-06-10 上海艾力斯医药科技有限公司 一种稳定的脂质体组合物
JP5196684B2 (ja) * 2007-06-22 2013-05-15 イノベイティブ サーフェイス テクノロジーズ, インコーポレイテッド 刺激応答性ナノ繊維
AU2008303466A1 (en) * 2007-09-28 2009-04-02 Universitatsspital Basel Immunoliposomes for treatment of cancer
US8079820B2 (en) * 2008-12-18 2011-12-20 General Electric Company Blade module, a modular rotor blade and a method for assembling a modular rotor blade
EP2394640A1 (fr) * 2010-05-21 2011-12-14 MediGene AG Formulations liposomales améliorées de composés lipophiles
WO2012133121A1 (fr) * 2011-03-25 2012-10-04 テルモ株式会社 Composition liposomale de longue durée à libération prolongée et son procédé de fabrication
US8987224B2 (en) * 2011-08-05 2015-03-24 Baylor College Of Medicine MicroRNA-198 as a tumor suppressor in pancreatic cancer
WO2013066903A1 (fr) * 2011-10-31 2013-05-10 Mallinckrodt Llc Compositions liposomales combinatoires pour le traitement du cancer
EP2604253A1 (fr) * 2011-12-13 2013-06-19 Otto Glatter Émulsion eau dans l'huile et leurs procédés de préparation
NZ700073A (en) * 2012-04-04 2016-08-26 Halozyme Inc Combination therapy with an anti - hyaluronan agent and a tumor - targeted taxane
CN102784107B (zh) * 2012-05-17 2015-04-22 江苏豪森药业股份有限公司 一种吉西他滨或其盐脂质体及其制备方法和用途
KR20150095809A (ko) * 2012-12-12 2015-08-21 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 암 치료용 조성물 및 방법
WO2014110555A1 (fr) * 2013-01-14 2014-07-17 Chemo-Enchanced Llc Compositions et procédés pour traiter le cancer
EP4378461A3 (fr) 2013-03-05 2024-09-11 The Regents of University of California Nanoparticules de silice mésoporeuse revêtues d'une bicouche lipidique présentant une capacité de charge élevée pour un ou plusieurs agents anticancéreux
JP6263609B2 (ja) 2014-04-30 2018-01-17 富士フイルム株式会社 リポソーム組成物及びその製造方法
WO2015166987A1 (fr) * 2014-04-30 2015-11-05 富士フイルム株式会社 Composition liposomale et procédé de production associé
JP6602886B2 (ja) 2015-11-02 2019-11-06 富士フイルム株式会社 ゲムシタビンリポソーム組成物を含む腫瘍治療剤およびキット
WO2017192863A1 (fr) * 2016-05-04 2017-11-09 L.E.A.F. Holdings Group Llc Compositions de gemcitabine liposomale ciblée et procédés correspondants

Also Published As

Publication number Publication date
RU2761620C2 (ru) 2021-12-13
EP3372232A1 (fr) 2018-09-12
RU2020137384A (ru) 2020-12-03
ES2869283T3 (es) 2021-10-25
WO2017078008A1 (fr) 2017-05-11
RU2738365C2 (ru) 2020-12-11
US11166914B2 (en) 2021-11-09
RU2020137385A3 (fr) 2021-03-31
JP6602886B2 (ja) 2019-11-06
CN108348538A (zh) 2018-07-31
CN111632030A (zh) 2020-09-08
DK3372232T3 (da) 2021-06-07
CN111632030B (zh) 2023-01-17
RU2018119680A (ru) 2019-12-05
RU2768178C2 (ru) 2022-03-23
EP3372232A4 (fr) 2018-11-14
RU2018119680A3 (fr) 2019-12-05
CN111437259A (zh) 2020-07-24
CN108348538B (zh) 2021-06-22
US20180243214A1 (en) 2018-08-30
US20200197305A1 (en) 2020-06-25
US11166913B2 (en) 2021-11-09
RU2020137385A (ru) 2020-12-03
KR20180054873A (ko) 2018-05-24
PL3372232T3 (pl) 2021-09-27
EP3372232B1 (fr) 2021-04-14
RU2020137384A3 (fr) 2021-03-31
JPWO2017078008A1 (ja) 2018-08-09
KR102084340B1 (ko) 2020-03-03
US20210275453A1 (en) 2021-09-09

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