MA43591A - Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement - Google Patents

Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement

Info

Publication number
MA43591A
MA43591A MA043591A MA43591A MA43591A MA 43591 A MA43591 A MA 43591A MA 043591 A MA043591 A MA 043591A MA 43591 A MA43591 A MA 43591A MA 43591 A MA43591 A MA 43591A
Authority
MA
Morocco
Prior art keywords
treatment
methods
subject requiring
inhibiting fibrosis
fibrosis
Prior art date
Application number
MA043591A
Other languages
English (en)
Inventor
Nigel John Brunskill
Gregory A Demopulos
Thomas Dudler
Hans-Wilhelm Schwaeble
Original Assignee
Omeros Corp
Univ Leicester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omeros Corp, Univ Leicester filed Critical Omeros Corp
Publication of MA43591A publication Critical patent/MA43591A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
MA043591A 2016-01-05 2017-01-05 Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement MA43591A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662275025P 2016-01-05 2016-01-05
US201662407979P 2016-10-13 2016-10-13

Publications (1)

Publication Number Publication Date
MA43591A true MA43591A (fr) 2021-05-26

Family

ID=59236184

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043591A MA43591A (fr) 2016-01-05 2017-01-05 Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement

Country Status (20)

Country Link
US (3) US10736960B2 (fr)
EP (1) EP3400012A4 (fr)
JP (3) JP6682653B2 (fr)
KR (4) KR102564616B1 (fr)
CN (3) CN117503923A (fr)
AU (4) AU2017205453B2 (fr)
CA (2) CA3185172A1 (fr)
CL (3) CL2018001817A1 (fr)
EA (1) EA201891570A1 (fr)
GE (2) GEP20217290B (fr)
IL (3) IL320282A (fr)
MA (1) MA43591A (fr)
MX (3) MX2018008331A (fr)
MY (1) MY194810A (fr)
NZ (1) NZ744629A (fr)
PH (1) PH12018501435A1 (fr)
SG (2) SG11201805695SA (fr)
UA (1) UA127339C2 (fr)
WO (1) WO2017120344A1 (fr)
ZA (1) ZA201805238B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101141544B1 (ko) 2009-03-13 2012-05-03 한국과학기술원 에스아이알엔에이 다중 접합체 및 이의 제조방법
IL316159A (en) 2015-06-15 2024-12-01 Mpeg La Llc Defined Oligonucleotide Multimers and Methods for Manufacture Thereof
SG11201805695SA (en) 2016-01-05 2018-07-30 Univ Leicester Methods for inhibiting fibrosis in a subject in need thereof
JOP20170170B1 (ar) 2016-08-31 2022-09-15 Omeros Corp صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق
JOP20190068B1 (ar) * 2016-10-13 2024-12-22 Omeros Corp طرق لتقليل البول البروتيني في خاضع بشري يعاني من الاعتلال الكلوي a الناتج عن الجلوبيولين المناعي
EP3576752A4 (fr) 2017-02-06 2020-12-16 Mpeg La, LLC Oligonucléotides multimères ayant une clairance rénale diminuée
BR112020003737A2 (pt) * 2017-08-31 2020-09-01 Novartis Ag usos de derivados de piperidinil-indol
CN111971297A (zh) * 2018-05-16 2020-11-20 韩国亿诺生物有限公司 包含lrit2抑制剂作为活性成分用于预防或治疗癌症的药物组合物
CN118373875A (zh) 2018-05-29 2024-07-23 奥默罗斯公司 Masp-2抑制剂和使用方法
WO2020186256A1 (fr) * 2019-03-14 2020-09-17 Aravive Inc Procédés de traitement d'une néphropathie à immunoglobuline a (igan) à l'aide de récepteurs leurres axl
WO2021026476A1 (fr) * 2019-08-08 2021-02-11 Mpeg La, L.L.C. Ciblage du complément avec des oligonucléotides multimères
KR20220104201A (ko) * 2019-11-26 2022-07-26 오메로스 코포레이션 조혈 줄기 세포 이식과 관련된 특발성 폐렴 증후군 (ips) 및/또는 모세혈관 누출 증후군 (cls) 및/또는 생착 증후군 (es) 및/또는 체액 과부하 (fo)를 치료 및/또는 예방하는 방법
KR20220110531A (ko) 2019-12-04 2022-08-08 오메로스 코포레이션 Masp-2 억제자 및 사용 방법
WO2021113698A1 (fr) 2019-12-04 2021-06-10 Omeros Corporation Inhibiteurs de masp-2 et procédés d'utilisation
WO2021113682A1 (fr) 2019-12-04 2021-06-10 Omeros Corporation Inhibiteurs de masp-2 et procédés d'utilisation
KR20220110529A (ko) 2019-12-04 2022-08-08 오메로스 코포레이션 Masp-2 억제자 및 사용 방법
KR20230015874A (ko) 2019-12-17 2023-01-31 치누크 세라퓨틱스, 인크. 아트라센탄에 의해 iga 신장병증을 치료하는 방법
CN111419860A (zh) * 2020-03-19 2020-07-17 长春市儿童医院 一种肾小球分叶状肾病造模方法
JP7826221B2 (ja) 2020-04-30 2026-03-09 エムペグ エルエイ リミテッド ライアビリティ カンパニー 分割鎖を有する多量体オリゴヌクレオチド
US12263144B2 (en) * 2020-10-13 2025-04-01 Accubit LLC—Biotechnology Methods of treating IgA nephropathy with thiol-containing molecules
CN120173119B (zh) * 2020-12-16 2025-09-30 康诺亚生物医药科技（成都）有限公司 一种补体抑制剂的开发和应用
EP4353749A4 (fr) * 2021-06-08 2025-07-16 Shanghai Jemincare Pharmaceuticals Co Ltd Anticorps anti-masp-2 et son utilisation
WO2023103789A1 (fr) * 2021-12-10 2023-06-15 舒泰神（北京）生物制药股份有限公司 Anticorps reconnaissant spécifiquement masp2 et son utilisation
PY22106817A (es) 2021-12-10 2023-12-21 Omeros Corp Anticuerpos terapéuticos que se unen al dominio serina-proteasa de masp-2 y usos de estos
WO2023173036A2 (fr) 2022-03-10 2023-09-14 Omeros Corporation Inhibiteurs de masp-2 et masp-3, et compositions et méthodes associées pour le traitement de la drépanocytose
US20250352511A1 (en) * 2022-05-19 2025-11-20 Chinook Therapeutics, Inc. Methods of treating focal segmental glomerulosclerosis with atrasentan
JP2025541737A (ja) 2022-11-30 2025-12-23 オメロス コーポレーション Ｍａｓｐ－２阻害物質としての縮合ピリミジン
WO2025076476A2 (fr) 2023-10-06 2025-04-10 Omeros Corporation Inhibiteurs de masp-2 et procédés d'utilisation

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331647A (en) 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5453566A (en) 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
AU632993B2 (en) 1987-12-15 1993-01-21 Gene Shears Pty. Limited Ribozymes
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB8822492D0 (en) 1988-09-24 1988-10-26 Considine J Apparatus for removing tumours from hollow organs of body
US5211657A (en) 1988-11-07 1993-05-18 The United States Government As Represented By The Secretary Of The Department Of Health And Human Services Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5549910A (en) 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
SG46445A1 (en) 1990-01-26 1998-02-20 Immunomedics Inc Vaccines against cancer and infectious diseases
JP3218637B2 (ja) 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
US5789573A (en) 1990-08-14 1998-08-04 Isis Pharmaceuticals, Inc. Antisense inhibition of ICAM-1, E-selectin, and CMV IE1/IE2
JP2958076B2 (ja) 1990-08-27 1999-10-06 株式会社ビタミン研究所 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
IL108367A0 (en) 1993-01-27 1994-04-12 Hektoen Inst For Medical Resea Antisense polynzcleotide inhibition of human growth factor-sensitive cancer cells
US5801154A (en) 1993-10-18 1998-09-01 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of multidrug resistance-associated protein
US5741516A (en) 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US5738868A (en) 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor
US5739119A (en) 1996-11-15 1998-04-14 Galli; Rachel L. Antisense oligonucleotides specific for the muscarinic type 2 acetylcholine receptor MRNA
US6649592B1 (en) 2000-01-14 2003-11-18 Science & Technology Corporation @ Unm Peptide inhibitors of LFA-1/ICAM-1 interaction
SG98393A1 (en) 2000-05-19 2003-09-19 Inst Materials Research & Eng Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
CA2490007C (fr) 2002-07-19 2011-05-24 Omeros Corporation Copolymeres triblocs biodegradables, procedes de synthese, et hydrogels et biomateriaux fabriques a partir de ces derniers
CN1798769A (zh) 2003-05-12 2006-07-05 内蒂穆恩公司 抗masp－2抗体
US7919094B2 (en) 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US8840893B2 (en) 2004-06-10 2014-09-23 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US20140056873A1 (en) * 2004-06-10 2014-02-27 University Of Leicester Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation
US7626730B2 (en) * 2006-03-31 2009-12-01 Eastman Kodak Company Method of making a multilevel halftone screen
AU2010306581B2 (en) 2009-10-16 2015-03-19 Omeros Corporation Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation
US9102721B2 (en) 2011-01-21 2015-08-11 Fibrogen, Inc. Therapeutic method
US9644035B2 (en) * 2011-04-08 2017-05-09 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
CN107638565B (zh) 2011-04-08 2021-12-21 莱斯特大学 用于治疗与masp-2依赖性补体活化相关的状况的方法
MX361175B (es) * 2011-05-04 2018-11-29 Omeros Corp Composiciones para inhibir la activación del complemento dependiente de la masp-2.
EP2861246B1 (fr) * 2012-06-18 2021-01-20 Omeros Corporation Compositions et procédés pour l'inhibition de masp-1 et/ou masp-2 et/ou masp-3 pour le traitement de divers troubles et maladies
AU2014229020B2 (en) 2013-03-15 2017-09-28 Omeros Corporation Methods of generating bioactive peptide-bearing antibodies and compositions comprising the same
RS61351B1 (sr) 2013-10-17 2021-02-26 Omeros Corp Postupci za lečenje stanja udruženih sa aktivacijom komplementa zavisnom od masp-2
SG11201805695SA (en) 2016-01-05 2018-07-30 Univ Leicester Methods for inhibiting fibrosis in a subject in need thereof
JOP20170170B1 (ar) * 2016-08-31 2022-09-15 Omeros Corp صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق
US20180105604A1 (en) 2016-10-13 2018-04-19 University Of Leicester Methods for reducing proteinuria in a human subject suffering from immunoglobulin a nephropathy
KR101930345B1 (ko) * 2016-12-20 2019-03-11 김은진 지혈제 조성물

Also Published As

Publication number Publication date
CL2018001817A1 (es) 2019-01-11
CN117503923A (zh) 2024-02-06
NZ783304A (en) 2025-05-02
ZA201805238B (en) 2023-05-31
KR102528260B1 (ko) 2023-05-04
JP2019504880A (ja) 2019-02-21
US10736960B2 (en) 2020-08-11
KR102780411B1 (ko) 2025-03-12
AU2022203914A1 (en) 2022-06-23
NZ744629A (en) 2020-06-26
US20170189525A1 (en) 2017-07-06
AU2022203914B2 (en) 2025-05-01
CL2020002444A1 (es) 2021-02-19
MX2024010937A (es) 2024-09-17
AU2020201804A1 (en) 2020-03-26
KR102564616B1 (ko) 2023-08-08
CA3185172A1 (fr) 2017-07-13
UA127339C2 (uk) 2023-07-26
IL260430B2 (en) 2023-06-01
AU2017205453B2 (en) 2020-03-12
MY194810A (en) 2022-12-16
JP6682653B2 (ja) 2020-04-15
CA3010593C (fr) 2024-02-13
JP7430208B2 (ja) 2024-02-09
GEAP202114848A (en) 2021-05-13
IL294411A (en) 2022-08-01
US20210077621A1 (en) 2021-03-18
KR20200116175A (ko) 2020-10-08
JP2022065145A (ja) 2022-04-26
PH12018501435A1 (en) 2019-03-04
IL294411B2 (en) 2025-10-01
US20240424091A1 (en) 2024-12-26
JP2020114845A (ja) 2020-07-30
IL294411B1 (en) 2025-06-01
CL2019001411A1 (es) 2019-08-02
BR112018013723A2 (pt) 2018-12-26
US12005117B2 (en) 2024-06-11
MX2018008331A (es) 2019-05-30
KR20180096794A (ko) 2018-08-29
NZ760818A (en) 2025-03-28
WO2017120344A1 (fr) 2017-07-13
AU2022221419B2 (en) 2025-04-24
IL260430A (fr) 2018-08-30
AU2020201804B2 (en) 2022-06-16
IL320282A (en) 2025-06-01
EA201891570A1 (ru) 2018-12-28
SG11201805695SA (en) 2018-07-30
CA3010593A1 (fr) 2017-07-13
AU2022221419A1 (en) 2022-11-10
EP3400012A4 (fr) 2019-12-11
MX2023007754A (es) 2023-07-07
AU2017205453A1 (en) 2018-08-16
KR20230080493A (ko) 2023-06-07
CN114306593A (zh) 2022-04-12
GEP20217290B (en) 2021-09-10
IL260430B1 (fr) 2023-02-01
SG10202001580SA (en) 2020-04-29
KR20220011791A (ko) 2022-01-28
KR102475622B1 (ko) 2022-12-08
EP3400012A1 (fr) 2018-11-14
CN108495652A (zh) 2018-09-04

Similar Documents

Publication Publication Date Title
EP3400012A4 (fr) Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement
EP3541386A4 (fr) Compositions et méthodes de traitement d'une prise excessive d'opioïdes
MA46954A (fr) Méthodes de traitement d'états inflammatoires
MA45192A (fr) Traitement d'association
EP3813806A4 (fr) Méthodes de traitement d'un dysfonctionnement mitochondrial
EP3436072A4 (fr) Procédés d'inhibition d'angiogenèse chez un sujet qui en a besoin
EP3291815A4 (fr) Méthodes de traitement d'une maladie neurodégénérative
EP3298140A4 (fr) Compositions pour le traitement d'états de calcification pathologique, et méthodes les utilisant
MA53329A (fr) Méthodes de traitement de l'épilepsie
EP3625971A4 (fr) Traitement d'audio spatial
MA43570A (fr) Thérapie génique pour traiter l'hypercholestérolémie familiale
MA53882A (fr) Méthodes de traitement de la sclérose en plaques
EP3454793A4 (fr) Bobines de traitement d'anévrisme
EP3458079A4 (fr) Compositions et méthodes pour le traitement de l'acné
PL3519142T3 (pl) Sposób obróbki powierzchniowej przedmiotu
EP3313186A4 (fr) Combinaison d'inhibiteurs de lpt-723 et de point de contrôle immunitaire et méthodes de traitement
EP3373951A4 (fr) Méthodes et compositions pour le traitement d'une épidermolyse bulleuse
EP3007722A4 (fr) Méthodes de traitement de l'hypotension
EP3347032A4 (fr) Traitement de l'ascite
EP2950762A4 (fr) Prévention et traitement d'une neuropathie
EP3595688A4 (fr) Thérapie génique pour traiter l'hypercholestérolémie familiale
EP3302458A4 (fr) Méthodes de prévention et de traitement de l'auto-immunité
MA43755A (fr) Méthodes de traitement ou de prévention d'une maladie du greffon contre l'hôte
EP3849605A4 (fr) Méthodes de traitement de la pancréatite
EP3294313A4 (fr) Méthodes associées à la prévention et et au traitement d'une pharmacorésistance