MA43872A - Procédé de traitement d'une glomérulopathie à c3 - Google Patents

Procédé de traitement d'une glomérulopathie à c3

Info

Publication number
MA43872A
MA43872A MA043872A MA43872A MA43872A MA 43872 A MA43872 A MA 43872A MA 043872 A MA043872 A MA 043872A MA 43872 A MA43872 A MA 43872A MA 43872 A MA43872 A MA 43872A
Authority
MA
Morocco
Prior art keywords
glomerulopathy
treatment
Prior art date
Application number
MA043872A
Other languages
English (en)
Inventor
Petrus Bekker
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Publication of MA43872A publication Critical patent/MA43872A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
MA043872A 2016-01-14 2017-01-12 Procédé de traitement d'une glomérulopathie à c3 MA43872A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662278788P 2016-01-14 2016-01-14
US201662280346P 2016-01-19 2016-01-19
US201662347450P 2016-06-08 2016-06-08
US201662397527P 2016-09-21 2016-09-21

Publications (1)

Publication Number Publication Date
MA43872A true MA43872A (fr) 2021-05-19

Family

ID=59312069

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043872A MA43872A (fr) 2016-01-14 2017-01-12 Procédé de traitement d'une glomérulopathie à c3

Country Status (18)

Country Link
US (3) US20170202821A1 (fr)
EP (1) EP3402486B1 (fr)
JP (4) JP7339733B2 (fr)
KR (1) KR102767008B1 (fr)
CN (1) CN108601790B (fr)
AU (1) AU2017207359C1 (fr)
BR (2) BR112018014222A2 (fr)
CA (1) CA3010735C (fr)
ES (1) ES3026359T3 (fr)
IL (1) IL260539B (fr)
MA (1) MA43872A (fr)
MX (2) MX2022006069A (fr)
NZ (1) NZ744083A (fr)
RU (1) RU2742888C2 (fr)
SG (1) SG11201805828YA (fr)
TW (1) TWI791423B (fr)
WO (1) WO2017123716A1 (fr)
ZA (1) ZA201804513B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS54998B1 (sr) 2008-12-22 2016-11-30 Chemocentryx Inc Antagonisti c5ar
RS56332B1 (sr) 2010-06-24 2017-12-29 Chemocentryx Inc Antagonisti c5ar
DK3200791T3 (da) 2014-09-29 2020-05-25 Chemocentryx Inc Fremgangsmåder og mellemprodukter i fremstilling af C5AR- antagonister
WO2017035405A1 (fr) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Composés amino pour le traitement de troubles immunitaires et inflammatoires
WO2017035409A1 (fr) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Composés aryle, hétéroaryle, et hétérocycliques pour le traitement de troubles immunitaires et inflammatoires
WO2017035401A1 (fr) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Composés amide pour le traitement de troubles immunitaires et inflammatoires
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
JP7339733B2 (ja) 2016-01-14 2023-09-06 ケモセントリックス，インコーポレイティド Ｃ３腎症を処置する方法
WO2018160891A1 (fr) 2017-03-01 2018-09-07 Achillion Pharmaceutical, Inc. Composés pharmaceutiques destinés au traitement de troubles médicaux
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
WO2019021091A1 (fr) * 2017-07-27 2019-01-31 Procter & Gamble International Operations Sa Compositions rafraîchissantes pulvérisables, à phase stable, comprenant des particules en suspension
EP3661493A4 (fr) 2017-08-02 2021-04-14 Achillion Pharmaceuticals, Inc. Régimes thérapeutiques pour le traitement de l'hémoglobinurie paroxystique nocturne
WO2019227102A1 (fr) * 2018-05-25 2019-11-28 Achillion Pharmaceuticals, Inc. Biomarqueurs de néphropathie associés à la voie alternative du complément
WO2020051538A1 (fr) * 2018-09-06 2020-03-12 Achillion Pharmaceuticals, Inc. Formes morphiques d'inhibiteurs du facteur d du complément
JP7443375B2 (ja) 2018-09-06 2024-03-05 アキリオン ファーマシューティカルズ， インコーポレーテッド 医学的障害の治療のための大環状化合物
KR20210093855A (ko) 2018-09-25 2021-07-28 아칠리온 파르마세우티칼스 인코포레이티드 보체 인자 d 억제제의 형태체 형태
WO2020112961A1 (fr) 2018-11-30 2020-06-04 Chemocentryx, Inc. Formulations de capsules
WO2020131974A1 (fr) 2018-12-17 2020-06-25 Achillion Pharmaceuticals, Inc. Dosage ciblé pour le traitement des troubles induits par le complément
IL312955B1 (en) 2019-03-11 2026-01-01 Inflarx Gmbh Fused piperidinyl bicyclic compounds and related compounds as C5a receptor modulators
BR112021018456A2 (pt) 2019-03-22 2021-11-23 Achillion Pharmaceuticals Inc Compostos farmacêuticos para o tratamento de distúrbios mediados por complemento
KR20230050364A (ko) * 2020-08-07 2023-04-14 키라 파마슈티칼스 (수조우) 엘티디. C5ar 억제제로서의 화합물
WO2022140258A1 (fr) * 2020-12-21 2022-06-30 Chemocentryx, Inc. Traitement de la glomérulopathie à c3 à l'aide d'un inhibiteur de c5a
CN115192563B (zh) * 2022-05-09 2023-10-13 北京大学第一医院 C3a/C3aR通路拮抗剂治疗原发性膜性肾病的用途

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1268002A (en) 1917-09-12 1918-05-28 William M Goodwin Measuring instrument.
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4686100A (en) 1985-04-02 1987-08-11 The Board Of Trustees Of The Leland Stanford Junior University Method for the treatment of adult respiratory distress syndrome
MXPA01002173A (es) 1998-08-28 2003-07-14 Scios Inc Inhibidores de p38-alfa cinasa.
RU2197288C2 (ru) * 1999-08-03 2003-01-27 Тверская медицинская академия Способ лечения больных хроническим гломерулонефритом
US6713502B2 (en) 2000-05-05 2004-03-30 Smithkline Beecham Corporation Anti-infectives
CA2418652C (fr) 2000-08-10 2010-03-23 Mitsubishi Pharma Corporation Nouveaux derives d'uree substitues en position 3, et leur utilisation en medecine
WO2002022556A1 (fr) 2000-09-14 2002-03-21 Mitsubishi Pharma Corporation Derives amides et utilisations associees
JP5260818B2 (ja) 2000-09-29 2013-08-14 ノバルティス・インターナショナル・ファーマシューティカル・リミテッド 高親和性低分子Ｃ５ａ受容体調節物質
ES2283594T5 (es) 2001-08-17 2016-03-15 Genentech, Inc. Inhibidores de la ruta del complemento que se unen a C5 y C5a sin impedir la formación de C5b
IL160700A0 (en) 2001-09-21 2004-08-31 Mitsubishi Pharma Corp 3-substituted-4-pyrimidone derivatives
ITMI20012025A1 (it) 2001-09-28 2003-03-28 Dompe Spa Sali di ammonio quaternari di omega-amminoalchilammidi di acidi r 2-aril-propionici e composizioni farmaceutiche che li contengono
US20030195192A1 (en) 2002-04-05 2003-10-16 Fortuna Haviv Nicotinamides having antiangiogenic activity
EP1487796A4 (fr) 2002-03-28 2005-11-16 Neurogen Corp Biarylamides substitues en tant que modulateurs du recepteur c5a
CA2479930A1 (fr) 2002-03-28 2003-10-09 Neurogen Corporation Tetrahydroisoquinoleines substituees servant de modulateurs du recepteur c5a
CA2480082A1 (fr) 2002-03-29 2003-10-16 Neurogen Corporation Therapie combinatoire pour le traitement de maladies faisant intervenir des composants inflammatoires
US20040014744A1 (en) 2002-04-05 2004-01-22 Fortuna Haviv Substituted pyridines having antiangiogenic activity
AU2003257094A1 (en) 2002-08-08 2004-02-25 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted benzimidazole compounds
US7169775B2 (en) 2002-08-21 2007-01-30 Neurogen Corporation Amino methyl imidazoles as C5a receptor modulators
FR2846654A1 (fr) 2002-11-05 2004-05-07 Servier Lab Nouveaux derives de la 2,3-dihydro-4(1h)-pyridinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2004043223A2 (fr) 2002-11-05 2004-05-27 The Regents Of The University Of Michigan Compositions et methodes de diagnostic et traitement de la sepsie
AU2003291403A1 (en) 2002-11-08 2004-06-03 Neurogen Corporation 3-substituted-6-aryl pyridined as ligands of c5a receptors
AU2003902354A0 (en) 2003-05-15 2003-05-29 Harkin, Denis W. Treatment of haemorrhagic shock
BRPI0410630A (pt) 2003-06-19 2006-06-13 Pfizer Prod Inc antagonista de nk1
WO2005007087A2 (fr) 2003-07-03 2005-01-27 Neurogen Corporation Derives (heterocycloalkyl)methyle substitues de type azole utilises comme modulateurs des recepteurs c5a
GB0325956D0 (en) 2003-11-06 2003-12-10 Addex Pharmaceuticals Sa Novel compounds
US8071624B2 (en) 2004-06-24 2011-12-06 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
WO2006071958A1 (fr) 2004-12-29 2006-07-06 Millennium Pharmaceuticals, Inc. Composes utilises comme antagonistes du recepteur de la chimiokine
JP4058106B2 (ja) 2005-02-18 2008-03-05 アストラゼネカ アクチボラグ 抗菌性のピペリジン誘導体
US7880004B2 (en) 2005-09-15 2011-02-01 Bristol-Myers Squibb Company Met kinase inhibitors
WO2007051062A2 (fr) 2005-10-28 2007-05-03 Chemocentryx, Inc. Dihydropyridines substituees et leurs methodes d'utilisation
ES2597843T3 (es) 2005-11-24 2017-01-23 Dompé Farmaceutici S.P.A. Derivados de (R)-arilalquilamino y composiciones farmacéuticas que los contienen
US20090220508A1 (en) 2006-03-15 2009-09-03 Alexion Pharmaceuticals, Inc. Treatment Of Paroxysmal Nocturnal Hemoglobinuria Patients By An Inhibitor Of Complement
WO2008022060A2 (fr) 2006-08-14 2008-02-21 Novartis Ag composés organiques et leurs utilisations
WO2008053270A2 (fr) * 2006-10-31 2008-05-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Utilisation d'un antagoniste du récepteur egfr pour le traitement de la glomérulonéphrite
AU2008272437A1 (en) 2007-06-29 2009-01-08 Torrent Pharmaceuticals Ltd. Novel substituted piperidones as HSP inducers
AU2009282480B2 (en) 2008-08-11 2015-05-07 Children's Medical Center Corporation Halofuginone analogs for inhibition of tRNA synthetases and uses thereof
US20110172126A1 (en) 2008-09-03 2011-07-14 Xenome Ltd Libraries of peptide conjugates and methods for making them
US20100074863A1 (en) 2008-09-17 2010-03-25 Yat Sun Or Anti-infective pyrrolidine derivatives and analogs
CA2742802C (fr) * 2008-11-10 2019-11-26 Alexion Pharmaceuticals, Inc. Procedes et compositions pour le traitement de troubles associes au complement
US20110275639A1 (en) 2008-12-22 2011-11-10 Chemocentryx, Inc. C5aR ANTAGONISTS
RS54998B1 (sr) 2008-12-22 2016-11-30 Chemocentryx Inc Antagonisti c5ar
WO2011035143A2 (fr) 2009-09-17 2011-03-24 The Regents Of The University Of Michigan Procédés et compositions pour inhiber des maladies et des états à médiation par rho
RS56332B1 (sr) 2010-06-24 2017-12-29 Chemocentryx Inc Antagonisti c5ar
US8147400B1 (en) * 2011-01-17 2012-04-03 Coloplast A/S Penile implant with dilatant liquid
EA201590053A1 (ru) * 2012-06-20 2015-08-31 Новартис Аг Модуляторы пути системы комплемента и их применение
JP2016523829A (ja) 2013-05-08 2016-08-12 ノヴォ ノルディスク アー／エス Ｃ５ａｒアンタゴニストの使用
DK3200791T3 (da) 2014-09-29 2020-05-25 Chemocentryx Inc Fremgangsmåder og mellemprodukter i fremstilling af C5AR- antagonister
JP7339733B2 (ja) 2016-01-14 2023-09-06 ケモセントリックス，インコーポレイティド Ｃ３腎症を処置する方法
EP3439658B1 (fr) 2016-04-04 2021-11-24 ChemoCentryx, Inc. Antagonistes de c5ar solubles
WO2022140258A1 (fr) 2020-12-21 2022-06-30 Chemocentryx, Inc. Traitement de la glomérulopathie à c3 à l'aide d'un inhibiteur de c5a

Also Published As

Publication number Publication date
BR122024002810A2 (pt) 2024-03-12
CA3010735C (fr) 2023-06-13
TW201726134A (zh) 2017-08-01
IL260539B (en) 2021-05-31
RU2742888C2 (ru) 2021-02-11
CN108601790B (zh) 2026-01-27
BR112018014222A2 (pt) 2018-12-11
US20170202821A1 (en) 2017-07-20
AU2017207359C1 (en) 2022-09-01
JP2024110998A (ja) 2024-08-16
JP7339733B2 (ja) 2023-09-06
RU2018129378A (ru) 2020-02-14
CN108601790A (zh) 2018-09-28
TWI791423B (zh) 2023-02-11
WO2017123716A1 (fr) 2017-07-20
US20220354837A1 (en) 2022-11-10
JP2021183625A (ja) 2021-12-02
EP3402486A4 (fr) 2019-08-28
RU2018129378A3 (fr) 2020-05-20
US11285138B2 (en) 2022-03-29
CA3010735A1 (fr) 2017-07-20
ZA201804513B (en) 2024-01-31
US11779576B2 (en) 2023-10-10
AU2017207359A1 (en) 2018-07-26
JP2023126235A (ja) 2023-09-07
MX2018008624A (es) 2018-12-10
US20190201388A1 (en) 2019-07-04
EP3402486A1 (fr) 2018-11-21
EP3402486B1 (fr) 2025-03-19
EP3402486C0 (fr) 2025-03-19
NZ744083A (en) 2022-07-01
ES3026359T3 (en) 2025-06-11
KR20180102642A (ko) 2018-09-17
AU2017207359B2 (en) 2022-04-14
JP7788814B2 (ja) 2025-12-19
JP2019501935A (ja) 2019-01-24
SG11201805828YA (en) 2018-08-30
KR102767008B1 (ko) 2025-02-11
MX2022006069A (es) 2023-01-12

Similar Documents

Publication Publication Date Title
MA43872A (fr) Procédé de traitement d'une glomérulopathie à c3
EP3370721A4 (fr) Traitement de l'ostéoarthrite
MA45192A (fr) Traitement d'association
EP3353841A4 (fr) Procédé de préparation et d'application de composites de carbone-sélénium
EP3558313A4 (fr) Substances pour le traitement d'affections liées à la stéatose hépatique
EP3331527A4 (fr) Procédés de traitement de troubles du développement à l'aide de pipradrol
EP3291815A4 (fr) Méthodes de traitement d'une maladie neurodégénérative
EP3389657A4 (fr) Procédés de traitement de l'hyperalgésie
EP3386655C0 (fr) Procédé pour le traitement de déchets
EP3852631A4 (fr) Procédé d'imagerie
EP3398957A4 (fr) Procédé de synthèse de l'ételcalcétide
EP3966554A4 (fr) Procédé d'identification d'une structure
EP3966555A4 (fr) Procédé d'identification d'une structure
EP3334432A4 (fr) Cerdulatinib pour le traitement du myélome
EP3717011A4 (fr) Procédé de traitement ou de prévention d'une lésion liée à l'ischémie-reperfusion
EP3454793A4 (fr) Bobines de traitement d'anévrisme
EP3305732A4 (fr) Procédé de traitement d'eaux usées
EP3356033A4 (fr) Procédé d'hydrogénation catalytique d'halonitroaromatiques
MA42423A (fr) Procédé de préparation d'un revêtement
EP3684342A4 (fr) Procédé de traitement
MA43106A (fr) Traitement de l'oligo-ovulation associée à la stéatose hepatique
EP3633713A4 (fr) Procédé de production d'une structure et structure
EP3498837A4 (fr) Procédé d'édition de génome
MA45973A (fr) Combinaisons d'inhibiteurs de btk pour le traitement du myélome multiple
EP3344650A4 (fr) Aav-epo pour le traitement d'animaux de compagnie