MA44873A - Composition pour le traitement de la dégénérescence maculaire liée a l'âge exsudative - Google Patents
Composition pour le traitement de la dégénérescence maculaire liée a l'âge exsudativeInfo
- Publication number
- MA44873A MA44873A MA044873A MA44873A MA44873A MA 44873 A MA44873 A MA 44873A MA 044873 A MA044873 A MA 044873A MA 44873 A MA44873 A MA 44873A MA 44873 A MA44873 A MA 44873A
- Authority
- MA
- Morocco
- Prior art keywords
- exsudative
- age
- treatment
- composition
- macular degeneration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662323184P | 2016-04-15 | 2016-04-15 | |
| US201662331100P | 2016-05-03 | 2016-05-03 | |
| US201762442946P | 2017-01-05 | 2017-01-05 | |
| US201762460515P | 2017-02-17 | 2017-02-17 | |
| US201762466721P | 2017-03-03 | 2017-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA44873A true MA44873A (fr) | 2019-03-13 |
Family
ID=59253994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA044873A MA44873A (fr) | 2016-04-15 | 2017-04-14 | Composition pour le traitement de la dégénérescence maculaire liée a l'âge exsudative |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11197937B2 (fr) |
| EP (1) | EP3452103A1 (fr) |
| JP (4) | JP7046828B2 (fr) |
| KR (2) | KR102574810B1 (fr) |
| AU (2) | AU2017248731B2 (fr) |
| CA (1) | CA3019426A1 (fr) |
| IL (2) | IL322403A (fr) |
| MA (1) | MA44873A (fr) |
| SG (2) | SG11201808426XA (fr) |
| WO (1) | WO2017180936A1 (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| BR112018013407A2 (en) | 2015-12-30 | 2018-12-18 | Kodiak Sciences Inc. | antibodies and conjugates thereof |
| IL322403A (en) * | 2016-04-15 | 2025-09-01 | Univ Pennsylvania | Preparations for the treatment of wet age-related macular degeneration |
| JP7685833B2 (ja) * | 2017-09-27 | 2025-05-30 | レジェンクスバイオ インコーポレーテッド | 翻訳後修飾された完全ヒト抗VEGF Fabによる眼疾患の治療 |
| CA3079565A1 (fr) * | 2017-10-18 | 2019-04-25 | Regenxbio Inc. | Traitement de maladies oculaires et d'un cancer du colon metastatique avec un piege a vegf avec modification post-traductionnelle humain |
| FI3717636T3 (fi) * | 2017-11-27 | 2023-06-01 | 4D Molecular Therapeutics Inc | Adenoassosioidun viruksen kapsidivariantteja ja käyttö angiogeneesin estämisessä |
| BR112020012336A2 (pt) * | 2017-12-19 | 2021-03-30 | Akouos, Inc. | Administração de anticorpos terapêuticos mediada por aav para o ouvido interno |
| US12558434B2 (en) * | 2018-02-20 | 2026-02-24 | The Trustees Of The University Of Pennsylvania | Compositions for treatment of wet age-related macular degeneration |
| SG11202008242XA (en) | 2018-03-02 | 2020-09-29 | Kodiak Sciences Inc | Il-6 antibodies and fusion constructs and conjugates thereof |
| JP2022049718A (ja) * | 2019-02-05 | 2022-03-30 | アステラス製薬株式会社 | アデノ随伴ウイルスを用いたcx3cl1遺伝子の導入による網膜変性疾患の治療 |
| EP3946467A1 (fr) * | 2019-04-03 | 2022-02-09 | REGENXBIO Inc. | Thérapie génique pour pathologies de l'?il |
| WO2020219868A1 (fr) * | 2019-04-24 | 2020-10-29 | Regenxbio Inc. | Agents thérapeutiques à base d'anticorps entièrement humains à modification post-traductionnelle |
| US20220227875A1 (en) * | 2019-05-31 | 2022-07-21 | University Of Florida Research Foundation, Incorporated | Vector-based therapy for thyroid disease |
| KR20250051157A (ko) | 2019-06-05 | 2025-04-16 | 리제너론 파아마슈티컬스, 인크. | 정밀 투여량 전달을 위한 디바이스 및 방법 |
| CN114502197A (zh) * | 2019-08-26 | 2022-05-13 | 再生生物股份有限公司 | 用全人经翻译后修饰的抗VEGF Fab治疗糖尿病性视网膜病变 |
| US20240108669A1 (en) * | 2019-10-07 | 2024-04-04 | Regenxbio Inc. | Adeno-associated virus vector pharmaceutical composition and methods |
| US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2021231491A1 (fr) * | 2020-05-11 | 2021-11-18 | University Of Florida Research Foundation, Incorporated | Correction de maladie par administration de vecteurs aav8 exprimant une naglu à codon optimisé |
| BR112022021786A2 (pt) * | 2020-05-12 | 2023-01-17 | Univ Pennsylvania | Composições úteis em tratamento de doença de krabbe |
| WO2021255589A1 (fr) * | 2020-06-16 | 2021-12-23 | Intas Pharmaceuticals Ltd. | Vecteur de virus adéno-associé (vaa) scfab anti-vegf et ses utilisations |
| WO2021255590A1 (fr) * | 2020-06-16 | 2021-12-23 | Intas Pharmaceuticals Ltd. | Vecteur de virus adéno-associé (aav) anti-vegf et ses utilisations |
| CN113952473A (zh) * | 2020-07-21 | 2022-01-21 | 英斯培瑞有限公司 | 用于治疗眼部疾病的组合物和方法 |
| MX2023004377A (es) * | 2020-10-16 | 2023-06-28 | Gyroscope Therapeutics Ltd | Acido nucleico que codifica una entidad anti-vegf y un regulador del complemento negativo y sus usos para el tratamiento de la degeneracion macular relacionada con la edad. |
| TW202233841A (zh) * | 2020-10-28 | 2022-09-01 | 美商銳進科斯生物股份有限公司 | 用於眼適應症之載體化抗TNF-α抗體 |
| CN116457373A (zh) * | 2020-10-29 | 2023-07-18 | 再生生物股份有限公司 | 用于眼部适应症的载体化TNF-α拮抗剂 |
| AU2021391433A1 (en) * | 2020-12-01 | 2023-06-22 | Akouos, Inc. | Anti-vegf antibody constructs and related methods for treating vestibular schwannoma associated symptoms |
| EP4284335A1 (fr) | 2021-02-01 | 2023-12-06 | RegenxBio Inc. | Thérapie génique de céroïdes-lipofuscinoses neuronales |
| CA3243517A1 (fr) * | 2022-02-02 | 2023-08-10 | Akouos, Inc. | Constructions d'anticorps anti-vegf et méthodes connexes pour le traitement de symptômes associés au neurinome de l'acoustique |
| CA3247507A1 (fr) | 2022-04-06 | 2023-10-12 | Regenxbio Inc. | Composition pharmaceutique comprenant un vecteur de virus adéno-associé (vaa) recombinant avec une cassette d'expression codant un transgène pour administration suprachoroïdienne |
| US20260034250A1 (en) | 2022-09-30 | 2026-02-05 | Regenxbio Inc. | Treatment of ocular diseases with recombinant viral vectors encoding anti-vegf fab |
| WO2025073297A1 (fr) * | 2023-10-06 | 2025-04-10 | 甘李药业股份有限公司 | Vecteur de virus aav exprimant une protéine de fusion anti-vegf et utilisation de vecteur de virus aav |
| WO2025160405A1 (fr) * | 2024-01-24 | 2025-07-31 | Duke University | Compositions et procédés de génération et de sécrétion de particules d'aav |
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|---|---|---|---|---|
| FI953812A0 (fi) | 1993-02-12 | 1995-08-11 | Univ Leland Stanford Junior | Kohdistettujen geenien säädelty transkriptio ja muita biologisia toimintoja |
| WO1996020951A1 (fr) | 1994-12-29 | 1996-07-11 | Massachusetts Institute Of Technology | Proteines chimeres de liaison d'adn |
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| EP1053241A1 (fr) | 1998-02-13 | 2000-11-22 | President And Fellows Of Harvard College | Agents de dimerisation, production et utilisation |
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| EP1224309A2 (fr) | 1999-10-21 | 2002-07-24 | Monsanto Company | Modification post-traductionnelle de proteines de recombinaison produites dans les plantes |
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| CN103555677B (zh) | 2001-11-13 | 2018-01-30 | 宾夕法尼亚大学托管会 | 检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法 |
| WO2003052051A2 (fr) | 2001-12-17 | 2003-06-26 | The Trustees Of The University Of Pennsylvania | Sequences du serotype 8 du virus associe a l'adenovirus (aav), vecteurs les contenant et utilisations correspondantes |
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| DK3211085T3 (da) | 2003-09-30 | 2021-06-21 | Univ Pennsylvania | Klader af adeno-associeret virus (aav), sekvenser, vektorer indeholdende disse og anvendelser deraf |
| US8999678B2 (en) | 2005-04-07 | 2015-04-07 | The Trustees Of The University Of Pennsylvania | Method of increasing the function of an AAV vector |
| US7456683B2 (en) | 2005-06-09 | 2008-11-25 | Panasonic Corporation | Amplitude error compensating device and quadrature skew error compensating device |
| BRPI0817182A2 (pt) | 2007-10-30 | 2015-03-17 | Genentech Inc | Método para purificar um anticorpo e composições |
| AR069501A1 (es) | 2007-11-30 | 2010-01-27 | Genentech Inc | Anticuerpos anti- vegf (factor de crecimiento endotelial vascular) |
| KR101010352B1 (ko) | 2008-05-30 | 2011-01-25 | 삼성중공업 주식회사 | 전력 제어 장치 및 방법 |
| DK2356270T3 (da) | 2008-11-07 | 2016-12-12 | Fabrus Llc | Kombinatoriske antistofbiblioteker og anvendelser deraf |
| WO2010138263A2 (fr) | 2009-05-28 | 2010-12-02 | University Of Massachusetts | Nouveaux virus adéno-associés (aav) et leurs utilisations |
| TWI510248B (zh) | 2009-06-17 | 2015-12-01 | Abbvie Biotherapeutics Inc | 抗-vegf抗體及其用途 |
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| US8628966B2 (en) | 2010-04-30 | 2014-01-14 | City Of Hope | CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer |
| US8663624B2 (en) | 2010-10-06 | 2014-03-04 | The Regents Of The University Of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
| EP2634253B1 (fr) | 2010-10-27 | 2016-05-11 | Jichi Medical University | Virions de virus adéno-associé pour le transfert de gènes dans des cellules neuronales |
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| DK4005603T3 (da) | 2011-04-22 | 2024-11-25 | Univ California | Adeno-associerede virus-virioner med variant kapsid og fremgangsmåder til anvendelse heraf |
| EP2559443A1 (fr) | 2011-08-16 | 2013-02-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédés et composition pharmaceutiques pour le traitement d'une maladie oculaire chez un sujet |
| US9169299B2 (en) | 2011-08-24 | 2015-10-27 | The Board Of Trustees Of The Leleand Stanford Junior University | AAV capsid proteins for nucleic acid transfer |
| US20130090375A1 (en) * | 2011-10-06 | 2013-04-11 | Cornell University | Virus-mediated delivery of bevacizumab for therapeutic applications |
| WO2013170078A1 (fr) | 2012-05-09 | 2013-11-14 | Oregon Health & Science University | Plasmides et vecteurs viraux associés à un adénovirus |
| TWI702955B (zh) | 2012-05-15 | 2020-09-01 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
| SG11201503637SA (en) | 2012-11-08 | 2015-06-29 | Clearside Biomedical Inc | Methods and devices for the treatment of ocular diseases in human subjects |
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| US9567376B2 (en) | 2013-02-08 | 2017-02-14 | The Trustees Of The University Of Pennsylvania | Enhanced AAV-mediated gene transfer for retinal therapies |
| EP2970946A4 (fr) | 2013-03-13 | 2016-09-07 | Philadelphia Children Hospital | Vecteurs viraux adéno-associés et méthodes d'utilisation associées |
| SG10201707319UA (en) * | 2013-03-15 | 2017-10-30 | Univ Pennsylvania | Compositions and methods for treating mpsi |
| US9585971B2 (en) | 2013-09-13 | 2017-03-07 | California Institute Of Technology | Recombinant AAV capsid protein |
| ES2857751T3 (es) | 2013-10-11 | 2021-09-29 | Massachusetts Eye & Ear Infirmary | Métodos para predecir secuencias de virus ancestrales y usos de los mismos |
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| GB201403684D0 (en) | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| US11555059B2 (en) | 2014-04-25 | 2023-01-17 | The Trustees Of The University Of Pennsylvania | LDLR variants and their use in compositions for reducing cholesterol levels |
| WO2015164757A1 (fr) | 2014-04-25 | 2015-10-29 | Oregon Health & Science University | Procedes de cartographie d'epitopes d'anticorps de neutralisation virale |
| DK3142750T3 (da) * | 2014-05-13 | 2020-09-14 | Univ Pennsylvania | Sammensætninger omfattende aav, som udtrykker dobbelt-antistofkonstrukter og anvendelser deraf |
| WO2015191508A1 (fr) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Capsides chimériques |
| US9840553B2 (en) * | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| US10064752B2 (en) | 2014-09-11 | 2018-09-04 | Orbit Biomedical Limited | Motorized suprachoroidal injection of therapeutic agent |
| CN108347932B (zh) | 2015-02-20 | 2022-09-13 | 衣阿华大学研究基金会 | 用于治疗遗传性眼病的方法和组合物 |
| US11535665B2 (en) * | 2015-05-13 | 2022-12-27 | The Trustees Of The University Of Pennsylvania | AAV-mediated expression of anti-influenza antibodies and methods of use thereof |
| CA2995849A1 (fr) | 2015-08-31 | 2017-03-09 | The Trustees Of The University Of Pennsylvania | Vecteur chimerique aav anti-vegf pour le traitement de cancers chez les canines |
| GB201519086D0 (en) | 2015-10-28 | 2015-12-09 | Syncona Partners Llp | Gene Therapy |
| CN108778330A (zh) | 2016-01-08 | 2018-11-09 | 科尼尔赛德生物医学公司 | 用阿柏西普和其他生物制品治疗后眼部障碍的方法和装置 |
| SG10202008378UA (en) | 2016-04-15 | 2020-10-29 | Regenxbio Inc | Treatment of ocular diseases with fully-human post-translationally modified anti-vegf fab |
| IL322403A (en) * | 2016-04-15 | 2025-09-01 | Univ Pennsylvania | Preparations for the treatment of wet age-related macular degeneration |
| JP7685833B2 (ja) | 2017-09-27 | 2025-05-30 | レジェンクスバイオ インコーポレーテッド | 翻訳後修飾された完全ヒト抗VEGF Fabによる眼疾患の治療 |
| EP3946467A1 (fr) | 2019-04-03 | 2022-02-09 | REGENXBIO Inc. | Thérapie génique pour pathologies de l'?il |
-
2017
- 2017-04-14 IL IL322403A patent/IL322403A/en unknown
- 2017-04-14 WO PCT/US2017/027529 patent/WO2017180936A1/fr not_active Ceased
- 2017-04-14 CA CA3019426A patent/CA3019426A1/fr active Pending
- 2017-04-14 IL IL262207A patent/IL262207B2/en unknown
- 2017-04-14 EP EP17734161.7A patent/EP3452103A1/fr active Pending
- 2017-04-14 MA MA044873A patent/MA44873A/fr unknown
- 2017-04-14 KR KR1020187032620A patent/KR102574810B1/ko active Active
- 2017-04-14 SG SG11201808426XA patent/SG11201808426XA/en unknown
- 2017-04-14 US US16/093,420 patent/US11197937B2/en active Active
- 2017-04-14 JP JP2018554334A patent/JP7046828B2/ja active Active
- 2017-04-14 AU AU2017248731A patent/AU2017248731B2/en active Active
- 2017-04-14 KR KR1020237029712A patent/KR102920104B1/ko active Active
- 2017-04-15 SG SG10201913159UA patent/SG10201913159UA/en unknown
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2021
- 2021-06-07 US US17/340,752 patent/US20220288238A1/en not_active Abandoned
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2022
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2024
- 2024-05-17 JP JP2024080598A patent/JP2024105617A/ja active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| SG11201808426XA (en) | 2018-10-30 |
| KR102920104B1 (ko) | 2026-02-02 |
| US11197937B2 (en) | 2021-12-14 |
| KR20190031196A (ko) | 2019-03-25 |
| CA3019426A1 (fr) | 2017-10-19 |
| JP2022141856A (ja) | 2022-09-29 |
| JP7111924B2 (ja) | 2022-08-02 |
| AU2024216307A1 (en) | 2024-10-17 |
| KR102574810B1 (ko) | 2023-09-08 |
| NZ746729A (en) | 2023-08-25 |
| JP7046828B2 (ja) | 2022-04-04 |
| AU2017248731A1 (en) | 2018-10-18 |
| IL262207A (en) | 2018-11-29 |
| IL262207B1 (en) | 2025-09-01 |
| IL322403A (en) | 2025-09-01 |
| US20220288238A1 (en) | 2022-09-15 |
| JP2019518427A (ja) | 2019-07-04 |
| KR20230130765A (ko) | 2023-09-12 |
| WO2017180936A1 (fr) | 2017-10-19 |
| JP2024105617A (ja) | 2024-08-06 |
| AU2017248731B2 (en) | 2024-08-29 |
| US20190381194A1 (en) | 2019-12-19 |
| SG10201913159UA (en) | 2020-02-27 |
| EP3452103A1 (fr) | 2019-03-13 |
| JP2022084809A (ja) | 2022-06-07 |
| IL262207B2 (en) | 2026-01-01 |
| JP7492556B2 (ja) | 2024-05-29 |
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