MA45367B1 - Tyrosine kinase inhibitors - Google Patents
Tyrosine kinase inhibitorsInfo
- Publication number
- MA45367B1 MA45367B1 MA45367A MA45367A MA45367B1 MA 45367 B1 MA45367 B1 MA 45367B1 MA 45367 A MA45367 A MA 45367A MA 45367 A MA45367 A MA 45367A MA 45367 B1 MA45367 B1 MA 45367B1
- Authority
- MA
- Morocco
- Prior art keywords
- tyrosine kinase
- kinase inhibitors
- compounds
- btk
- inhibitors
- Prior art date
Links
- 229940121358 tyrosine kinase inhibitor Drugs 0.000 title 1
- 239000005483 tyrosine kinase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003112 inhibitor Substances 0.000 abstract 2
- 102000001714 Agammaglobulinaemia Tyrosine Kinase Human genes 0.000 abstract 1
- 108010029445 Agammaglobulinaemia Tyrosine Kinase Proteins 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 208000001435 Thromboembolism Diseases 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne des composés qui sont des inhibiteurs de la tyrosine kinase, en particulier des inhibiteurs de la tyrosine kinase de bruton ("btk"), et sont par conséquent utiles pour le traitement de maladies pouvant être traitées par l'inhibition de la btk telle que le cancer, les maladies auto-immunes, inflammatoires, et thromboemboliques. L'invention concerne également des compositions pharmaceutiques contenant de tels composés et des procédés de préparation de tels composés.The present invention relates to compounds which are inhibitors of tyrosine kinase, in particular inhibitors of bruton tyrosine kinase ("btk"), and therefore are useful for the treatment of diseases treatable by inhibition of the. btk such as cancer, autoimmune, inflammatory, and thromboembolic diseases. The invention also relates to pharmaceutical compositions containing such compounds and to methods of preparing such compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562170547P | 2015-06-03 | 2015-06-03 | |
| PCT/US2016/035588 WO2016196840A1 (en) | 2015-06-03 | 2016-06-02 | Tyrosine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA45367B1 true MA45367B1 (en) | 2021-09-30 |
Family
ID=59724528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA45367A MA45367B1 (en) | 2015-06-03 | 2016-06-02 | Tyrosine kinase inhibitors |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR104865A1 (en) |
| EC (1) | ECSP18000097A (en) |
| ES (1) | ES3075337T3 (en) |
| MA (1) | MA45367B1 (en) |
-
2016
- 2016-06-02 ES ES21169631T patent/ES3075337T3/en active Active
- 2016-06-02 AR ARP160101618A patent/AR104865A1/en active IP Right Grant
- 2016-06-02 MA MA45367A patent/MA45367B1/en unknown
-
2018
- 2018-01-02 EC ECIEPI201897A patent/ECSP18000097A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP18000097A (en) | 2018-10-31 |
| AR104865A1 (en) | 2017-08-23 |
| ES3075337T3 (en) | 2026-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA62580B1 (en) | BICYCLIC AMINES USED AS CDK2 INHIBITORS | |
| ZA202401324B (en) | Tyrosine kinase inhibitors | |
| MA49809A1 (en) | Compounds used as kinase inhibitors | |
| PH12022550892A1 (en) | Bicyclic heterocycles as fgfr inhibitors | |
| EA202091709A1 (en) | DNA PC INHIBITORS | |
| EA202091708A1 (en) | DNA PC INHIBITORS | |
| MA39219B1 (en) | New lrrk2 Kinase Inhibitor Compounds Used to Treat Parkinson's, Alzheimer's and Amyotrophic Lateral Sclerosis | |
| MA40111B1 (en) | Derivatives of tetrahydronaphthalene inhibiting mcl-1 protein | |
| MA52494B1 (en) | SOLID FORMS OF AN FGFR INHIBITOR AND METHODS OF PREPARATION THEREOF | |
| MA40768A (en) | MONO OR DI-SUBSTITUTE INDOLE DERIVATIVES AS DENGUE VIRUS REPLICATION INHIBITORS | |
| TN2014000420A1 (en) | INDOLE AND INDAZOLE DERIVATIVES THAT ACTIVATE MPK | |
| MA38284A1 (en) | Inhibitors of 2,3-dihydroimidazol [1,2-c] pyrimidin-5 (1 h) -one-2-lipoprotein-associated phospholipase (lp-pla2) | |
| MA41238A (en) | DERIVATIVES 5 - [(PIPERAZIN-1-YL) -3-OXO-PROPYL] -IMIDAZOLIDINE-2,4-DIONE AS ADAMT INHIBITORS FOR THE TREATMENT OF OSTEOARTHRIT | |
| GEAP202215599A (en) | Boron containing pde4 inhibitors | |
| PH12022551623A1 (en) | Substituted pyrazolo-pyrimidines and uses thereof | |
| MA40875A (en) | 2,4-DIAMINO-QUINOLEIN SUBSTITUTED AS NEW ANTI-CANCER AGENTS | |
| MA40366A (en) | TETRAHYDROQUINOLINE DERIVATIVES AS BROMODOMA INHIBITORS | |
| MA54940B1 (en) | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | |
| MX2021007967A (en) | Leukotriene synthesis inhibitors. | |
| MA35860B1 (en) | Quinoline derivatives as pde10a enzyme inhibitors | |
| MA49994B1 (en) | Macrocyclic compounds for the treatment of disease | |
| MA54770B1 (en) | COMPOUNDS USED AS KINASE INHIBITORS | |
| MA43507B1 (en) | Mono or di-substituted indole derivatives as dengue virus replication inhibitors | |
| MA42175B1 (en) | Pyrazolopyrimidine derivatives as btk inhibitors for cancer treatment | |
| MA51297B1 (en) | Quinazolinones as parp14 inhibitors |