MA45603A - Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble - Google Patents

Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Info

Publication number
MA45603A
MA45603A MA045603A MA45603A MA45603A MA 45603 A MA45603 A MA 45603A MA 045603 A MA045603 A MA 045603A MA 45603 A MA45603 A MA 45603A MA 45603 A MA45603 A MA 45603A
Authority
MA
Morocco
Prior art keywords
guanylate cyclase
new processes
soluble guanylate
preparing soluble
cyclase stimulators
Prior art date
Application number
MA045603A
Other languages
English (en)
Inventor
Vishnu Vardhan Reddy Karnati
Robert C Livingston
Song Xue
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MA45603A publication Critical patent/MA45603A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA045603A 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble MA45603A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662359453P 2016-07-07 2016-07-07

Publications (1)

Publication Number Publication Date
MA45603A true MA45603A (fr) 2019-05-15

Family

ID=59416789

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045603A MA45603A (fr) 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Country Status (15)

Country Link
US (4) US11319308B2 (fr)
EP (2) EP3481818B1 (fr)
JP (1) JP7112384B2 (fr)
KR (1) KR102487872B1 (fr)
CN (2) CN121673266A (fr)
AU (1) AU2017291827B2 (fr)
BR (1) BR112019000291A2 (fr)
CL (2) CL2019000016A1 (fr)
EA (1) EA201990237A1 (fr)
ES (1) ES2963563T3 (fr)
IL (1) IL263995B (fr)
MA (1) MA45603A (fr)
MX (2) MX389920B (fr)
SG (1) SG11201900096QA (fr)
WO (1) WO2018009597A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201990236A1 (ru) 2016-07-07 2019-08-30 Сайклерион Терапьютикс, Инк. Новые способы получения стимуляторов растворимой гуанилатциклазы
KR102487872B1 (ko) 2016-07-07 2023-01-12 사이클리온 테라퓨틱스, 인크. 가용성 구아닐레이트 시클라제 자극제의 신규 제조 방법
WO2019161534A1 (fr) * 2018-02-22 2019-08-29 Ironwood Pharmaceuticals, Inc. Nouveaux procédés et intermédiaires pour la préparation de stimulateurs de guanylate cyclase soluble
CN111902410B (zh) 2018-01-10 2024-04-19 赛克里翁治疗有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的方法及中间物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011150156A2 (fr) * 2010-05-26 2011-12-01 Sunovion Pharmaceuticals Inc. Composés hétéroarylés et leurs procédés d'utilisation
TWI532737B (zh) 2010-06-30 2016-05-11 艾諾屋製藥公司 可溶性鳥苷酸環化酶(sGC)刺激物
CA2861804C (fr) 2011-12-27 2021-10-26 Ironwood Pharmaceuticals, Inc. Pyrazoles 2-benzyle, 3-(pyrimidin-2-yle)-substitues utiles comme stimulateurs de scg
EP2897953B8 (fr) * 2012-09-19 2019-06-26 Cyclerion Therapeutics, Inc. Stimulateurs de sgc
ES2911276T3 (es) * 2013-03-15 2022-05-18 Cyclerion Therapeutics Inc Estimuladores de sGC
JP2016540017A (ja) * 2013-12-11 2016-12-22 アイアンウッド ファーマシューティカルズ インコーポレイテッド sGC刺激物質
US10844064B2 (en) * 2014-09-17 2020-11-24 Cyclerion Therapeutics, Inc. sGC stimulators
CN107223125B (zh) * 2014-09-17 2019-09-27 赛科理音医疗有限公司 sGC刺激剂
EP3194382B1 (fr) 2014-09-17 2021-09-08 Cyclerion Therapeutics, Inc. Dérivés de pyrazole utilisés comme stimulateurs de sgc
WO2016044445A2 (fr) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
BR112018011154B1 (pt) * 2015-11-30 2023-09-26 Cyclerion Therapeutics, Inc Dispersões sólidas compreendendo um estimulador de sgc
KR102487872B1 (ko) 2016-07-07 2023-01-12 사이클리온 테라퓨틱스, 인크. 가용성 구아닐레이트 시클라제 자극제의 신규 제조 방법
EA201990236A1 (ru) * 2016-07-07 2019-08-30 Сайклерион Терапьютикс, Инк. Новые способы получения стимуляторов растворимой гуанилатциклазы
EA039753B1 (ru) 2016-07-07 2022-03-10 Сайклерион Терапьютикс, Инк. ТВЕРДЫЕ ФОРМЫ СТИМУЛЯТОРА sGC
JP7337067B2 (ja) * 2017-12-19 2023-09-01 サイクレリオン・セラピューティクス,インコーポレーテッド sGC刺激薬
CN111902410B (zh) * 2018-01-10 2024-04-19 赛克里翁治疗有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的方法及中间物

Also Published As

Publication number Publication date
CL2019000016A1 (es) 2019-05-03
AU2017291827A1 (en) 2019-02-07
AU2017291827B2 (en) 2021-10-21
EP3481818A1 (fr) 2019-05-15
CN121673266A (zh) 2026-03-17
BR112019000291A2 (pt) 2019-04-16
NZ750123A (en) 2025-02-28
SG11201900096QA (en) 2019-02-27
CA3029375A1 (fr) 2018-01-11
IL263995B (en) 2021-02-28
JP2019525913A (ja) 2019-09-12
KR102487872B1 (ko) 2023-01-12
ES2963563T3 (es) 2024-03-27
WO2018009597A1 (fr) 2018-01-11
IL263995A (en) 2019-02-28
US11319308B2 (en) 2022-05-03
JP7112384B2 (ja) 2022-08-03
MX389920B (es) 2025-03-20
US20260103457A1 (en) 2026-04-16
CN109563077B (zh) 2026-03-10
EA201990237A1 (ru) 2019-08-30
US20220227748A1 (en) 2022-07-21
KR20190025986A (ko) 2019-03-12
MX2022001495A (es) 2022-03-11
EP3481818C0 (fr) 2023-09-06
EP3481818B1 (fr) 2023-09-06
US20240059684A1 (en) 2024-02-22
CN109563077A (zh) 2019-04-02
US11773089B2 (en) 2023-10-03
EP4249488A3 (fr) 2023-12-20
MX2019000105A (es) 2019-04-22
US20210323951A1 (en) 2021-10-21
CL2023000228A1 (es) 2023-09-29
EP4249488A2 (fr) 2023-09-27

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