MA45603A - Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble - Google Patents

Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Info

Publication number
MA45603A
MA45603A MA045603A MA45603A MA45603A MA 45603 A MA45603 A MA 45603A MA 045603 A MA045603 A MA 045603A MA 45603 A MA45603 A MA 45603A MA 45603 A MA45603 A MA 45603A
Authority
MA
Morocco
Prior art keywords
guanylate cyclase
new processes
soluble guanylate
preparing soluble
cyclase stimulators
Prior art date
Application number
MA045603A
Other languages
English (en)
Inventor
Vishnu Vardhan Reddy Karnati
Robert C Livingston
Song Xue
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MA45603A publication Critical patent/MA45603A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA045603A 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble MA45603A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662359453P 2016-07-07 2016-07-07

Publications (1)

Publication Number Publication Date
MA45603A true MA45603A (fr) 2019-05-15

Family

ID=59416789

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045603A MA45603A (fr) 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Country Status (16)

Country Link
US (4) US11319308B2 (fr)
EP (2) EP4249488A3 (fr)
JP (1) JP7112384B2 (fr)
KR (1) KR102487872B1 (fr)
CN (2) CN109563077B (fr)
AU (1) AU2017291827B2 (fr)
BR (1) BR112019000291A2 (fr)
CA (1) CA3029375A1 (fr)
CL (2) CL2019000016A1 (fr)
EA (1) EA201990237A1 (fr)
ES (1) ES2963563T3 (fr)
IL (1) IL263995B (fr)
MA (1) MA45603A (fr)
MX (2) MX389920B (fr)
SG (1) SG11201900096QA (fr)
WO (1) WO2018009597A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109563086B (zh) 2016-07-07 2023-05-23 赛克里翁治疗有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的方法
CN109563077B (zh) 2016-07-07 2026-03-10 赛克里翁治疗有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的新方法
US11274096B2 (en) 2018-01-10 2022-03-15 Cyclerion Therapeutics, Inc. Processes and intermediates for the preparation of soluble guanylate cyclase stimulators
WO2019161534A1 (fr) * 2018-02-22 2019-08-29 Ironwood Pharmaceuticals, Inc. Nouveaux procédés et intermédiaires pour la préparation de stimulateurs de guanylate cyclase soluble

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8969349B2 (en) * 2010-05-26 2015-03-03 Sunovion Pharmaceuticals Inc. Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors
EP2588465B1 (fr) 2010-06-30 2017-01-25 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
CN106117194A (zh) * 2011-12-27 2016-11-16 铁木医药有限公司 可用作sgc刺激剂的2‑苄基、3‑(嘧啶‑2‑基)取代的吡唑类
EP2897953B8 (fr) * 2012-09-19 2019-06-26 Cyclerion Therapeutics, Inc. Stimulateurs de sgc
EA033168B1 (ru) 2013-03-15 2019-09-30 Сайклерион Терапьютикс, Инк. СТИМУЛЯТОРЫ sGC
CA2933250A1 (fr) 2013-12-11 2015-06-18 Ironwood Pharmaceuticals, Inc. Stimulateurs de la sgc
EP3194386A2 (fr) * 2014-09-17 2017-07-26 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
EP3194382B1 (fr) * 2014-09-17 2021-09-08 Cyclerion Therapeutics, Inc. Dérivés de pyrazole utilisés comme stimulateurs de sgc
EA201790627A1 (ru) * 2014-09-17 2017-09-29 Айронвуд Фармасьютикалз, Инк. СТИМУЛЯТОРЫ рГЦ
US20170298055A1 (en) * 2014-09-17 2017-10-19 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
CA3006746C (fr) * 2015-11-30 2024-01-30 Ironwood Pharmaceuticals, Inc. Dispersions solides comprenant un stimulateur de guanylate cyclase soluble (sgc)
CN109563086B (zh) * 2016-07-07 2023-05-23 赛克里翁治疗有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的方法
CN109563087A (zh) 2016-07-07 2019-04-02 铁木医药有限公司 sGC刺激剂的固体形式
CN109563077B (zh) 2016-07-07 2026-03-10 赛克里翁治疗有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的新方法
MX2020006433A (es) * 2017-12-19 2020-09-17 Cyclerion Therapeutics Inc Estimuladores de guanilato ciclasa soluble (sgc).
US11274096B2 (en) * 2018-01-10 2022-03-15 Cyclerion Therapeutics, Inc. Processes and intermediates for the preparation of soluble guanylate cyclase stimulators

Also Published As

Publication number Publication date
US11773089B2 (en) 2023-10-03
IL263995B (en) 2021-02-28
CN109563077B (zh) 2026-03-10
US20240059684A1 (en) 2024-02-22
CA3029375A1 (fr) 2018-01-11
US20220227748A1 (en) 2022-07-21
JP7112384B2 (ja) 2022-08-03
EP3481818B1 (fr) 2023-09-06
US11319308B2 (en) 2022-05-03
ES2963563T3 (es) 2024-03-27
EP3481818C0 (fr) 2023-09-06
US20210323951A1 (en) 2021-10-21
AU2017291827B2 (en) 2021-10-21
NZ750123A (en) 2025-02-28
KR102487872B1 (ko) 2023-01-12
MX389920B (es) 2025-03-20
IL263995A (en) 2019-02-28
CN121673266A (zh) 2026-03-17
EP4249488A2 (fr) 2023-09-27
KR20190025986A (ko) 2019-03-12
SG11201900096QA (en) 2019-02-27
EP4249488A3 (fr) 2023-12-20
EP3481818A1 (fr) 2019-05-15
CN109563077A (zh) 2019-04-02
CL2019000016A1 (es) 2019-05-03
WO2018009597A1 (fr) 2018-01-11
BR112019000291A2 (pt) 2019-04-16
JP2019525913A (ja) 2019-09-12
MX2022001495A (es) 2022-03-11
MX2019000105A (es) 2019-04-22
EA201990237A1 (ru) 2019-08-30
CL2023000228A1 (es) 2023-09-29
US20260103457A1 (en) 2026-04-16
AU2017291827A1 (en) 2019-02-07

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