MA46058A - Vésicules d'ester de cholestéryle chargeant des peptides, des protéines et des acides nucléiques dans des chylomicrons et des cellules corporelles - Google Patents

Vésicules d'ester de cholestéryle chargeant des peptides, des protéines et des acides nucléiques dans des chylomicrons et des cellules corporelles

Info

Publication number
MA46058A
MA46058A MA046058A MA46058A MA46058A MA 46058 A MA46058 A MA 46058A MA 046058 A MA046058 A MA 046058A MA 46058 A MA46058 A MA 46058A MA 46058 A MA46058 A MA 46058A
Authority
MA
Morocco
Prior art keywords
chylomicrons
proteins
nucleic acids
cholesteryl ester
body cells
Prior art date
Application number
MA046058A
Other languages
English (en)
Inventor
Mary P Mccourt
Lawrence Mielnicki
Jerome J Schentag
Original Assignee
Mary P Mccourt
Lawrence Mielnicki
Jerome J Schentag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mary P Mccourt, Lawrence Mielnicki, Jerome J Schentag filed Critical Mary P Mccourt
Publication of MA46058A publication Critical patent/MA46058A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA046058A 2016-08-23 2017-08-23 Vésicules d'ester de cholestéryle chargeant des peptides, des protéines et des acides nucléiques dans des chylomicrons et des cellules corporelles MA46058A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662378599P 2016-08-23 2016-08-23

Publications (1)

Publication Number Publication Date
MA46058A true MA46058A (fr) 2019-07-03

Family

ID=61245234

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046058A MA46058A (fr) 2016-08-23 2017-08-23 Vésicules d'ester de cholestéryle chargeant des peptides, des protéines et des acides nucléiques dans des chylomicrons et des cellules corporelles

Country Status (7)

Country Link
US (2) US20190175515A1 (fr)
EP (1) EP3503876A4 (fr)
JP (1) JP2019528294A (fr)
CN (1) CN110418636A (fr)
AU (1) AU2017315321A1 (fr)
MA (1) MA46058A (fr)
WO (1) WO2018039303A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9119782B2 (en) 2006-03-20 2015-09-01 Mary P. McCourt Drug delivery means
MX384232B (es) 2013-03-14 2025-03-14 Jerome J Schentag Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones.
BR112019015797A2 (pt) 2017-02-01 2020-03-17 Modernatx, Inc. Composições de mrna terapêuticas imunomoduladoras que codificam peptídeos de mutação de oncogene de ativação
CN114099780A (zh) * 2020-08-31 2022-03-01 易成刚 同种异体或异种脂肪萃取液及其制备方法、应用
JP7735624B2 (ja) * 2020-08-31 2025-09-09 武田薬品工業株式会社 推論装置、推論方法、推論プログラム、モデル生成方法、推論サービス提供システム、推論サービス提供方法及び推論サービス提供プログラム
EP4219738A4 (fr) * 2020-09-25 2024-10-02 Suzhou Ersheng Biopharmaceutical Co., Ltd Procédé de détection de lymphocytes t spécifiques d'une tumeur
CN115369091B (zh) * 2022-09-29 2023-07-28 成都赛诺联创生物科技有限公司 一种Caco-2细胞倒置模型及其制备方法
CN118207158B (zh) * 2023-06-21 2024-08-27 天津医科大学眼科医院 一种细胞内来源的纳米囊泡的制备方法及应用
WO2025226829A1 (fr) * 2024-04-23 2025-10-30 Ashvattha Therapeutics, Inc. Formulations de dendrimères et leurs utilisations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874560A (en) * 1994-04-22 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Melanoma antigens and their use in diagnostic and therapeutic methods
US9119782B2 (en) * 2006-03-20 2015-09-01 Mary P. McCourt Drug delivery means
JP2009143963A (ja) * 2009-03-25 2009-07-02 Sinan Tas 腫瘍細胞のアポトーシスを阻害するためにヘッジホッグ/スムーズンド信号を使用する腫瘍を治療するための製薬組成物
CA3008794C (fr) * 2012-03-29 2021-03-16 Therabiome, Llc Formulations de vaccination orale specifiques a un site gastro-intestinal actives sur l'ileon et l'appendice
MX384232B (es) * 2013-03-14 2025-03-14 Jerome J Schentag Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones.
WO2016155809A1 (fr) * 2015-03-31 2016-10-06 Biontech Rna Pharmaceuticals Gmbh Formulations de particules lipidiques permettant la délivrance à une cellule cible d'arn et de composés hydrosolubles thérapeutiquement efficaces

Also Published As

Publication number Publication date
US20190175515A1 (en) 2019-06-13
WO2018039303A1 (fr) 2018-03-01
EP3503876A4 (fr) 2020-06-10
US20230240997A1 (en) 2023-08-03
EP3503876A1 (fr) 2019-07-03
AU2017315321A1 (en) 2019-04-11
JP2019528294A (ja) 2019-10-10
CN110418636A (zh) 2019-11-05

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