MA46460A - Formes cristallines et salines de composés agonistes de ppar - Google Patents
Formes cristallines et salines de composés agonistes de pparInfo
- Publication number
- MA46460A MA46460A MA046460A MA46460A MA46460A MA 46460 A MA46460 A MA 46460A MA 046460 A MA046460 A MA 046460A MA 46460 A MA46460 A MA 46460A MA 46460 A MA46460 A MA 46460A
- Authority
- MA
- Morocco
- Prior art keywords
- crystalline
- agonist compounds
- ppar agonist
- saline forms
- saline
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404474P | 2016-10-05 | 2016-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46460A true MA46460A (fr) | 2021-03-17 |
Family
ID=60153508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046460A MA46460A (fr) | 2016-10-05 | 2017-10-05 | Formes cristallines et salines de composés agonistes de ppar |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US10927094B2 (fr) |
| EP (1) | EP3523283B1 (fr) |
| JP (1) | JP7017563B2 (fr) |
| KR (1) | KR20190057129A (fr) |
| CN (1) | CN109843857B (fr) |
| AU (1) | AU2017340763B2 (fr) |
| CA (1) | CA3036587A1 (fr) |
| CO (1) | CO2019003162A2 (fr) |
| CY (1) | CY1124655T1 (fr) |
| DK (1) | DK3523283T3 (fr) |
| ES (1) | ES2887008T3 (fr) |
| HR (1) | HRP20211341T1 (fr) |
| HU (1) | HUE055678T2 (fr) |
| IL (1) | IL265730B (fr) |
| JO (1) | JOP20190039B1 (fr) |
| LT (1) | LT3523283T (fr) |
| MA (1) | MA46460A (fr) |
| MX (1) | MX385973B (fr) |
| MY (1) | MY202008A (fr) |
| PH (1) | PH12019500727A1 (fr) |
| PL (1) | PL3523283T3 (fr) |
| PT (1) | PT3523283T (fr) |
| RS (1) | RS62245B1 (fr) |
| RU (1) | RU2759724C2 (fr) |
| SG (1) | SG11201901995TA (fr) |
| SI (1) | SI3523283T1 (fr) |
| TW (1) | TWI769182B (fr) |
| UA (1) | UA124770C2 (fr) |
| WO (1) | WO2018067860A1 (fr) |
| ZA (1) | ZA201901744B (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2336117A1 (fr) | 2005-05-26 | 2011-06-22 | Neuron Systems, Inc | Composés hétérocycliques pour le traitement des maladies rétiniennes |
| WO2011072141A1 (fr) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions et procédés pour le traitement de la dégénérescence maculaire |
| CA2898631C (fr) | 2013-01-23 | 2023-06-13 | Aldeyra Therapeutics, Inc. | Maladies liees a un aldehyde toxique et traitement |
| CN108135907A (zh) | 2015-08-21 | 2018-06-08 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
| MX392524B (es) * | 2015-10-07 | 2025-03-24 | Salk Inst Biological Studies | Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar |
| EP3523283B1 (fr) | 2016-10-05 | 2021-06-09 | Mitobridge, Inc. | Formes cristallines et salines de composés agonistes de ppar |
| MX2020003425A (es) | 2017-10-10 | 2020-07-29 | Aldeyra Therapeutics Inc | Tratamiento de trastornos inflamatorios. |
| EP3833660A4 (fr) * | 2018-08-06 | 2022-05-11 | Aldeyra Therapeutics, Inc. | Composés polymorphes et leurs utilisations |
| CN112912069A (zh) * | 2018-10-23 | 2021-06-04 | 国立研究开发法人科学技术振兴机构 | PPARδ激活剂 |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| CA3137301A1 (fr) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Composes polymorphes et leurs utilisations |
| WO2021231792A1 (fr) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Formulations pharmaceutiques et leurs utilisations |
| BR112023025221A2 (pt) | 2021-06-02 | 2024-02-27 | Astellas Pharma Inc | Métodos de uso de compostos agonistas de ppar e composições farmacêuticas dos mesmos |
| WO2023147309A1 (fr) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Utilisation d'agonistes ppar-delta dans le traitement d'une maladie |
| WO2025207099A1 (fr) * | 2024-03-28 | 2025-10-02 | Astellas Pharma Inc. | Inhibiteurs de ppar-delta pour prévenir une fibrillation auriculaire post-opératoire |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004063165A1 (fr) | 2003-01-06 | 2004-07-29 | Eli Lilly And Company | Derive de pyrazole utilise comme modulateur du recepteur ppar |
| EP1671633A1 (fr) * | 2004-12-17 | 2006-06-21 | Sanofi-Aventis Deutschland GmbH | Utilisation de PPAR agonistes pour traiter l'insuffisance cardiaque congestive |
| CN101141957A (zh) * | 2005-02-03 | 2008-03-12 | Irm责任有限公司 | 作为ppar调节剂的化合物和组合物 |
| CN101296892A (zh) * | 2005-09-07 | 2008-10-29 | 普莱希科公司 | Ppar活性化合物 |
| DE102006023336A1 (de) | 2006-05-18 | 2007-11-22 | Merck Patent Gmbh | 1,5-Diphenyl-pyrazole II |
| FR2940289B1 (fr) | 2008-12-23 | 2014-09-12 | Biopharmed | Derives de la classe des hydroxyquinoleines aminees pour le traitement du cancer du pancreas |
| CN102727489A (zh) * | 2012-07-18 | 2012-10-17 | 西南大学 | 5-芳(杂环)亚甲基噻唑烷-2，4-二酮在制备ppar激动剂中的应用 |
| WO2016057658A1 (fr) * | 2014-10-08 | 2016-04-14 | Mitobridge, Inc. | Agonistes de ppar, composés, compositions pharmaceutiques et méthodes d'utilisation de ceux-ci |
| MX392524B (es) | 2015-10-07 | 2025-03-24 | Salk Inst Biological Studies | Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar |
| BR112018069930B1 (pt) | 2016-04-13 | 2024-02-20 | Mitobridge, Inc | Compostos agonistas de ppar, uso dos mesmos e composição farmacêutica |
| EP3523283B1 (fr) | 2016-10-05 | 2021-06-09 | Mitobridge, Inc. | Formes cristallines et salines de composés agonistes de ppar |
| MY192385A (en) | 2016-10-05 | 2022-08-18 | Mitobridge Inc | Methods of treating acute kidney injury |
-
2017
- 2017-10-05 EP EP17787774.3A patent/EP3523283B1/fr active Active
- 2017-10-05 RS RS20211042A patent/RS62245B1/sr unknown
- 2017-10-05 HR HRP20211341TT patent/HRP20211341T1/hr unknown
- 2017-10-05 DK DK17787774.3T patent/DK3523283T3/da active
- 2017-10-05 MX MX2019003945A patent/MX385973B/es unknown
- 2017-10-05 TW TW106134298A patent/TWI769182B/zh active
- 2017-10-05 US US16/334,746 patent/US10927094B2/en active Active
- 2017-10-05 IL IL265730A patent/IL265730B/en unknown
- 2017-10-05 PT PT177877743T patent/PT3523283T/pt unknown
- 2017-10-05 WO PCT/US2017/055403 patent/WO2018067860A1/fr not_active Ceased
- 2017-10-05 MA MA046460A patent/MA46460A/fr unknown
- 2017-10-05 CN CN201780062034.5A patent/CN109843857B/zh active Active
- 2017-10-05 MY MYPI2019001560A patent/MY202008A/en unknown
- 2017-10-05 ES ES17787774T patent/ES2887008T3/es active Active
- 2017-10-05 RU RU2019110736A patent/RU2759724C2/ru active
- 2017-10-05 JO JOP/2019/0039A patent/JOP20190039B1/ar active
- 2017-10-05 KR KR1020197012668A patent/KR20190057129A/ko not_active Ceased
- 2017-10-05 PL PL17787774T patent/PL3523283T3/pl unknown
- 2017-10-05 SI SI201730879T patent/SI3523283T1/sl unknown
- 2017-10-05 JP JP2019518286A patent/JP7017563B2/ja active Active
- 2017-10-05 CA CA3036587A patent/CA3036587A1/fr active Pending
- 2017-10-05 UA UAA201903678A patent/UA124770C2/uk unknown
- 2017-10-05 LT LTEPPCT/US2017/055403T patent/LT3523283T/lt unknown
- 2017-10-05 AU AU2017340763A patent/AU2017340763B2/en active Active
- 2017-10-05 SG SG11201901995TA patent/SG11201901995TA/en unknown
- 2017-10-05 HU HUE17787774A patent/HUE055678T2/hu unknown
-
2019
- 2019-03-20 ZA ZA2019/01744A patent/ZA201901744B/en unknown
- 2019-03-29 CO CONC2019/0003162A patent/CO2019003162A2/es unknown
- 2019-04-03 PH PH12019500727A patent/PH12019500727A1/en unknown
-
2021
- 2021-02-19 US US17/179,604 patent/US11530192B2/en active Active
- 2021-08-31 CY CY20211100775T patent/CY1124655T1/el unknown
-
2022
- 2022-12-16 US US18/082,847 patent/US11912681B2/en active Active
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