MA46642A - Promédicaments d'inhibiteurs de la kallicréine - Google Patents

Promédicaments d'inhibiteurs de la kallicréine

Info

Publication number
MA46642A
MA46642A MA046642A MA46642A MA46642A MA 46642 A MA46642 A MA 46642A MA 046642 A MA046642 A MA 046642A MA 46642 A MA46642 A MA 46642A MA 46642 A MA46642 A MA 46642A
Authority
MA
Morocco
Prior art keywords
kallicrein
medicinal products
inhibitor
inhibitor medicinal
products
Prior art date
Application number
MA046642A
Other languages
English (en)
Inventor
Yarlagadda S Babu
Venkat R Chintareddy
Pravin L Kotian
V Satish Kumar
Lakshminarayana Vogeti
Weihe Zhang
Original Assignee
Biocryst Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocryst Pharm Inc filed Critical Biocryst Pharm Inc
Publication of MA46642A publication Critical patent/MA46642A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MA046642A 2016-10-31 2017-10-27 Promédicaments d'inhibiteurs de la kallicréine MA46642A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662415202P 2016-10-31 2016-10-31

Publications (1)

Publication Number Publication Date
MA46642A true MA46642A (fr) 2021-04-21

Family

ID=62025466

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046642A MA46642A (fr) 2016-10-31 2017-10-27 Promédicaments d'inhibiteurs de la kallicréine

Country Status (9)

Country Link
US (2) US10759759B2 (fr)
EP (1) EP3532057B1 (fr)
JP (1) JP7128181B2 (fr)
AU (1) AU2017348305B2 (fr)
DK (1) DK3532057T3 (fr)
ES (1) ES2942285T3 (fr)
IL (1) IL266223B2 (fr)
MA (1) MA46642A (fr)
WO (1) WO2018081513A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA46642A (fr) 2016-10-31 2021-04-21 Biocryst Pharm Inc Promédicaments d'inhibiteurs de la kallicréine
JP7668227B2 (ja) 2019-04-08 2025-04-24 バイオクライスト ファーマシューティカルズ, インコーポレイテッド 血漿カリクレイン阻害剤および眼障害におけるその使用方法
CN115835860B (zh) * 2020-06-12 2026-03-24 树顶分子生技股份有限公司 用于治疗非酒精性脂肪性肝病和非酒精性脂肪性肝炎的带有碳酸酯的紫檀芪氨基酸的类似物
CN111646936A (zh) * 2020-06-22 2020-09-11 江苏亚虹医药科技有限公司 芳香醚类化合物的制备方法
CN114933584B (zh) * 2021-08-09 2022-12-27 上海贵之言医药科技有限公司 一种二氢-2h-异吲哚酯类化合物

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
LU86084A1 (fr) 1985-09-20 1987-04-02 Faco Sa Apparei de massage electrique
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
WO1990013332A1 (fr) 1989-05-11 1990-11-15 Cedars-Sinai Medical Center Support pour medicaments a liberation progressive
WO1991012779A1 (fr) 1990-02-28 1991-09-05 Medtronic, Inc. Prothese pour l'elution intraluminale d'un medicament
US5419760A (en) 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
US5429634A (en) 1993-09-09 1995-07-04 Pdt Systems Biogenic implant for drug delivery and method
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
WO2002034711A1 (fr) 2000-10-20 2002-05-02 Biocryst Pharmaceuticals, Inc. Composes biaryle utilises comme inhibiteurs de serine protease
ES2332090T3 (es) 2001-04-06 2010-01-26 Biocryst Pharmaceuticals, Inc. Compuestos biarilicos como inhibidores de serina proteasa.
WO2004002985A1 (fr) 2002-06-27 2004-01-08 Lg Life Sciences Ltd. Compose peptidique inhibiteur de la thrombine
US6770729B2 (en) 2002-09-30 2004-08-03 Medtronic Minimed, Inc. Polymer compositions containing bioactive agents and methods for their use
GB0301938D0 (en) 2003-01-28 2003-02-26 Biochemie Gmbh Organic compounds
MX2009003533A (es) 2006-10-06 2009-07-17 Toyama Chemical Co Ltd Composición farmacéutica que comprende derivado de fenilamidina y método para usar la composición farmacéutica en combinación con el aceite antifúngico.
KR20100026641A (ko) 2008-09-01 2010-03-10 동아제약주식회사 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법
US9359376B2 (en) 2011-04-08 2016-06-07 Sphaera Pharma Pte. Ltd Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds
CA3123900A1 (en) 2011-07-28 2013-01-31 Kempharm Inc. Methylphenidate-prodrugs, processes of making and using the same
TWI601725B (zh) 2012-08-27 2017-10-11 加拓科學公司 取代的氮雜吲哚化合物及其鹽、組合物和用途
ES2731837T3 (es) 2012-12-21 2019-11-19 Ratiopharm Gmbh Profármacos de fumarato de monometilo (MMF)
WO2015042375A1 (fr) 2013-09-20 2015-03-26 Idenix Pharmaceuticals, Inc. Inhibiteurs du virus de l'hépatite c
US9499532B2 (en) 2014-02-07 2016-11-22 eXIthera Pharmaceuticals Inc. Therapeutic compounds and compositions
WO2016029216A2 (fr) * 2014-08-22 2016-02-25 Biocryst Pharmaceuticals, Inc. Procédé de production de dérivés d'amidine
US10905683B2 (en) 2014-08-22 2021-02-02 Biocryst Pharmaceuticals, Inc. Compositions and uses of amidine derivatives
MA46642A (fr) 2016-10-31 2021-04-21 Biocryst Pharm Inc Promédicaments d'inhibiteurs de la kallicréine

Also Published As

Publication number Publication date
US20190382344A1 (en) 2019-12-19
EP3532057A4 (fr) 2020-07-01
US11618731B2 (en) 2023-04-04
DK3532057T3 (da) 2023-02-20
EP3532057B1 (fr) 2022-12-21
EP3532057A1 (fr) 2019-09-04
IL266223A (en) 2019-06-30
AU2017348305B2 (en) 2022-04-21
US20210198204A1 (en) 2021-07-01
IL266223B1 (en) 2023-12-01
CA3041058A1 (fr) 2018-05-03
IL266223B2 (en) 2024-04-01
US10759759B2 (en) 2020-09-01
ES2942285T3 (es) 2023-05-31
AU2017348305A1 (en) 2019-05-30
WO2018081513A1 (fr) 2018-05-03
JP7128181B2 (ja) 2022-08-30
JP2019535688A (ja) 2019-12-12

Similar Documents

Publication Publication Date Title
EP3430731A4 (fr) Architecture d'iugw
EP3314590A4 (fr) Alerte de proximité d'articles
DK3935068T3 (da) Abirateron-prodrugs
EP3443293A4 (fr) Capteurs d'effort
EP3426242A4 (fr) Icaritine et dérivés d'icaritine
BR112017001684A2 (pt) preparação de produto de proteína de pulso ("yp810")
MA49006A (fr) Inhibiteurs d'ip6k
EP3525841A4 (fr) Micro-dispositif d'administration
CL2019000563S1 (es) Envase y dispendio de medicamentos. (divisional solicitud 201800718)
EP3431808A4 (fr) Butée d'arrêt
EP3522872A4 (fr) Formulations d'amlodipine
MA44987A (fr) Formulations de médicaments améliorées
DK3280447T3 (da) Farmaceutiske formuleringer
EP3426210A4 (fr) Produit d'incontinence
EP3444345A4 (fr) Dérivé d'arnmicro-143
MA43764A (fr) Inhibiteur monovalent de l'interaction hutnfr1
EP3416672A4 (fr) Formulations d'oritavancine
EP3777728C0 (fr) Dispositif médical
ES1141665Y (es) Dispositivo para la administración de un producto cosmético
EP3903780A4 (fr) Produit médicinal
HUE057830T2 (hu) Famitinib tartalmú gyógyszerkészítmény
FR3035837B1 (fr) Plaque d'immatriculation
IT201700090331A1 (it) "lopemide"
UA36577S (uk) Етикетка для упаковки лікарського засобу «гропівірін»
IT201700071679A1 (it) Remembebe'