MA46864A - Facteur vii inhibé par le site actif marqué par 177-lu - Google Patents

Facteur vii inhibé par le site actif marqué par 177-lu

Info

Publication number
MA46864A
MA46864A MA046864A MA46864A MA46864A MA 46864 A MA46864 A MA 46864A MA 046864 A MA046864 A MA 046864A MA 46864 A MA46864 A MA 46864A MA 46864 A MA46864 A MA 46864A
Authority
MA
Morocco
Prior art keywords
inhibited
active site
factor vii
site marked
marked
Prior art date
Application number
MA046864A
Other languages
English (en)
Inventor
Nielsen Carsten Haagen
Andreas Kjaer
Original Assignee
Minerva Imaging Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minerva Imaging Aps filed Critical Minerva Imaging Aps
Publication of MA46864A publication Critical patent/MA46864A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
MA046864A 2016-11-17 2017-11-17 Facteur vii inhibé par le site actif marqué par 177-lu MA46864A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201670913 2016-11-17

Publications (1)

Publication Number Publication Date
MA46864A true MA46864A (fr) 2021-04-28

Family

ID=62146130

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046864A MA46864A (fr) 2016-11-17 2017-11-17 Facteur vii inhibé par le site actif marqué par 177-lu

Country Status (4)

Country Link
US (2) US20190358351A1 (fr)
EP (1) EP3541432A4 (fr)
MA (1) MA46864A (fr)
WO (1) WO2018091058A1 (fr)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4338689A (en) 1988-09-23 1990-04-18 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
US5190919A (en) 1989-11-13 1993-03-02 Board Of Regents, The University Of Texas System Antihemostatic factor vii peptides
US5861374A (en) * 1991-02-28 1999-01-19 Novo Nordisk A/S Modified Factor VII
US5833982A (en) 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
US5788965A (en) 1991-02-28 1998-08-04 Novo Nordisk A/S Modified factor VII
JP3459416B2 (ja) 1991-02-28 2003-10-20 ザイモジェネティクス，インコーポレイティド 修飾されたファクター▲ｖｉｉ▼
PT699075E (pt) 1993-05-21 2002-05-31 Novo Nordisk As Factor vii modificado para inibicao de restenose vascular e de deposicao de plaquetas
CN1125450A (zh) 1993-06-18 1996-06-26 哈夫思伦·尼卡姆德公司 因子vii衍生的肽
GB9425380D0 (en) 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
US6500934B1 (en) 1996-07-24 2002-12-31 Michael Rush Lerner Bivalent agonists for G-protein coupled receptors
AU775621B2 (en) 1999-07-01 2004-08-05 Yale University Neovascular-targeted immunoconjugates
WO2001021661A1 (fr) 1999-09-20 2001-03-29 Novo Nordisk A/S INHIBITEUR BIVALENT DU COMPLEXE FVIIa/TF/FXa
WO2004007557A2 (fr) * 2002-07-12 2004-01-22 Novo Nordisk A/S Antagoniste du facteur tissulaire
JP2006516564A (ja) * 2003-01-22 2006-07-06 ノボ　ノルディスク　アクティーゼルスカブ Ｔｆ結合薬剤及びそれらの使用
US20140023585A1 (en) * 2010-11-22 2014-01-23 Universitatsspital Basel 177 lutetium-labeled bombesin analogs for radiotherapy
CN104768573B (zh) * 2012-05-08 2017-08-29 Trt创新有限责任公司 用于位点特异性uPAR靶向的177‑Lu标记肽

Also Published As

Publication number Publication date
US20230146930A1 (en) 2023-05-11
US20190358351A1 (en) 2019-11-28
EP3541432A1 (fr) 2019-09-25
WO2018091058A1 (fr) 2018-05-24
EP3541432A4 (fr) 2020-08-05

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