MA46896A - Composés d'alcène tétrasubstitués et leur utilisation - Google Patents

Composés d'alcène tétrasubstitués et leur utilisation

Info

Publication number
MA46896A
MA46896A MA046896A MA46896A MA46896A MA 46896 A MA46896 A MA 46896A MA 046896 A MA046896 A MA 046896A MA 46896 A MA46896 A MA 46896A MA 46896 A MA46896 A MA 46896A
Authority
MA
Morocco
Prior art keywords
alcene
tetrasubstituted
compounds
tetrasubstituted alcene
alcene compounds
Prior art date
Application number
MA046896A
Other languages
English (en)
Inventor
Mark Bock
Ming-Hong Hao
Manav Korpal
Nicholas Larsen
Lorna Helen Mitchell
Vijay Kumar Nyavanandi
Xiaoling Puyang
Nathalie Rioux
Susanta Samajdar
Peter Gerard Smith
John Wang
Guo Zhu Zheng
Ping Zhu
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of MA46896A publication Critical patent/MA46896A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
MA046896A 2016-11-24 2017-11-22 Composés d'alcène tétrasubstitués et leur utilisation MA46896A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN201641040208 2016-11-24

Publications (1)

Publication Number Publication Date
MA46896A true MA46896A (fr) 2019-10-02

Family

ID=60923887

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046896A MA46896A (fr) 2016-11-24 2017-11-22 Composés d'alcène tétrasubstitués et leur utilisation

Country Status (6)

Country Link
US (1) US20190337921A1 (fr)
EP (1) EP3544956A1 (fr)
JP (1) JP2019535781A (fr)
CN (1) CN110267940A (fr)
MA (1) MA46896A (fr)
WO (1) WO2018098251A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019400398B2 (en) * 2018-12-17 2024-10-03 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Estrogen receptor antagonist
US12325696B2 (en) * 2019-06-19 2025-06-10 Jiangsu Hengrui Medicine Co., Ltd. Indazole derivative, preparation method therefor, and pharmaceutical application thereof
CN114644615B (zh) * 2020-12-18 2023-11-14 江苏恒瑞医药股份有限公司 一种吲唑类衍生物的结晶形式及其制备方法
CN114644616B (zh) * 2020-12-18 2023-11-14 江苏恒瑞医药股份有限公司 一种吲唑类衍生物的药学上可接受的盐、结晶形式及其制备方法
WO2022127904A1 (fr) * 2020-12-18 2022-06-23 江苏恒瑞医药股份有限公司 Sel pharmaceutiquement acceptable de dérivé d'indazole, forme cristalline et procédé de préparation associé
TW202241861A (zh) * 2020-12-30 2022-11-01 大陸商正大天晴藥業集團股份有限公司 四取代烯烴類化合物的鹽型、結晶及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1175397E (pt) * 1999-05-04 2005-01-31 Ligand Pharm Inc Derivados de indolina substituidos em 3,3
WO2009120999A2 (fr) * 2008-03-28 2009-10-01 Olema Pharmaceuticals, Inc. Utilisation d’un promédicament d’endoxifène dans le traitement du cancer de la poitrine
WO2011129837A1 (fr) * 2010-04-16 2011-10-20 Olema Pharmaceuticals, Inc. Emploi d'un promédicament de type 4-hydroxytorémifène dans le traitement du cancer du sein
GB2483736B (en) * 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
GB201311891D0 (en) * 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
SG11201607334YA (en) * 2014-03-13 2016-10-28 Hoffmann La Roche Therapeutic combinations with estrogen receptor modulators
RS62481B1 (sr) * 2015-05-29 2021-11-30 Eisai R&D Man Co Ltd Jedinjenja tetrasupstituisanog alkena i njihova upotreba

Also Published As

Publication number Publication date
JP2019535781A (ja) 2019-12-12
EP3544956A1 (fr) 2019-10-02
WO2018098251A1 (fr) 2018-05-31
CN110267940A (zh) 2019-09-20
US20190337921A1 (en) 2019-11-07

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