MA46896A - Composés d'alcène tétrasubstitués et leur utilisation - Google Patents

Composés d'alcène tétrasubstitués et leur utilisation

Info

Publication number
MA46896A
MA46896A MA046896A MA46896A MA46896A MA 46896 A MA46896 A MA 46896A MA 046896 A MA046896 A MA 046896A MA 46896 A MA46896 A MA 46896A MA 46896 A MA46896 A MA 46896A
Authority
MA
Morocco
Prior art keywords
alcene
tetrasubstituted
compounds
tetrasubstituted alcene
alcene compounds
Prior art date
Application number
MA046896A
Other languages
English (en)
Inventor
Mark Bock
Ming-Hong Hao
Manav Korpal
Nicholas Larsen
Lorna Helen Mitchell
Vijay Kumar Nyavanandi
Xiaoling Puyang
Nathalie Rioux
Susanta Samajdar
Peter Gerard Smith
John Wang
Guo Zhu Zheng
Ping Zhu
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of MA46896A publication Critical patent/MA46896A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
MA046896A 2016-11-24 2017-11-22 Composés d'alcène tétrasubstitués et leur utilisation MA46896A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN201641040208 2016-11-24

Publications (1)

Publication Number Publication Date
MA46896A true MA46896A (fr) 2019-10-02

Family

ID=60923887

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046896A MA46896A (fr) 2016-11-24 2017-11-22 Composés d'alcène tétrasubstitués et leur utilisation

Country Status (6)

Country Link
US (1) US20190337921A1 (fr)
EP (1) EP3544956A1 (fr)
JP (1) JP2019535781A (fr)
CN (1) CN110267940A (fr)
MA (1) MA46896A (fr)
WO (1) WO2018098251A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021007088A (es) * 2018-12-17 2021-09-08 Chia Tai Tianqing Pharmaceutical Group Co Ltd Antagonista del receptor de estrogeno.
KR20220024476A (ko) * 2019-06-19 2022-03-03 지앙수 헨그루이 메디슨 컴퍼니 리미티드 인다졸 유도체, 이의 제조 방법, 및 이의 약제학적 적용
CN114644615B (zh) * 2020-12-18 2023-11-14 江苏恒瑞医药股份有限公司 一种吲唑类衍生物的结晶形式及其制备方法
CN116615418B (zh) * 2020-12-18 2025-11-11 江苏恒瑞医药股份有限公司 一种吲唑类衍生物的药学上可接受的盐、结晶形式及其制备方法
CN114644616B (zh) * 2020-12-18 2023-11-14 江苏恒瑞医药股份有限公司 一种吲唑类衍生物的药学上可接受的盐、结晶形式及其制备方法
US20240043401A1 (en) * 2020-12-30 2024-02-08 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Salt form of tetra-substituted olefin compound, crystal, and preparation method therefor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4806200A (en) * 1999-05-04 2000-11-17 American Home Products Corporation 3,3-substituted indoline derivatives
WO2009120999A2 (fr) * 2008-03-28 2009-10-01 Olema Pharmaceuticals, Inc. Utilisation d’un promédicament d’endoxifène dans le traitement du cancer de la poitrine
WO2011129837A1 (fr) * 2010-04-16 2011-10-20 Olema Pharmaceuticals, Inc. Emploi d'un promédicament de type 4-hydroxytorémifène dans le traitement du cancer du sein
GB2483736B (en) * 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
GB201311891D0 (en) * 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
JP2017507964A (ja) * 2014-03-13 2017-03-23 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト エストロゲン受容体モジュレーターを用いた治療的組合せ
PL3302471T3 (pl) * 2015-05-29 2022-02-07 Eisai R&D Management Co., Ltd. Tetrapodstawione związki alkenowe i ich zastosowanie

Also Published As

Publication number Publication date
US20190337921A1 (en) 2019-11-07
WO2018098251A1 (fr) 2018-05-31
CN110267940A (zh) 2019-09-20
EP3544956A1 (fr) 2019-10-02
JP2019535781A (ja) 2019-12-12

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