MA47014A - Procédé de purification d'antibiotiques lipopeptidiques - Google Patents

Procédé de purification d'antibiotiques lipopeptidiques

Info

Publication number
MA47014A
MA47014A MA047014A MA47014A MA47014A MA 47014 A MA47014 A MA 47014A MA 047014 A MA047014 A MA 047014A MA 47014 A MA47014 A MA 47014A MA 47014 A MA47014 A MA 47014A
Authority
MA
Morocco
Prior art keywords
lipopeptidic
antibiotics
purification process
purification
lipopeptidic antibiotics
Prior art date
Application number
MA047014A
Other languages
English (en)
Inventor
Mauro Rossini
Auro Roberto Tagliani
Ermanno Valoti
Original Assignee
Gnosis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Spa filed Critical Gnosis Spa
Publication of MA47014A publication Critical patent/MA47014A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA047014A 2016-12-16 2017-12-12 Procédé de purification d'antibiotiques lipopeptidiques MA47014A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000127655A IT201600127655A1 (it) 2016-12-16 2016-12-16 Processo per la purificazione di antibiotici lipopolipeptidici

Publications (1)

Publication Number Publication Date
MA47014A true MA47014A (fr) 2019-10-23

Family

ID=58545105

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047014A MA47014A (fr) 2016-12-16 2017-12-12 Procédé de purification d'antibiotiques lipopeptidiques

Country Status (10)

Country Link
US (1) US20210355160A1 (fr)
EP (1) EP3555114A1 (fr)
AU (1) AU2017376192A1 (fr)
BR (1) BR112019012273A2 (fr)
CA (1) CA3045214A1 (fr)
IT (1) IT201600127655A1 (fr)
MA (1) MA47014A (fr)
MX (1) MX2019007072A (fr)
PH (1) PH12019501183A1 (fr)
WO (1) WO2018108896A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800006314A1 (it) * 2018-06-14 2019-12-14 Uso di resine a scambio cationico per la purificazione di antibiotici lipopolipeptidici
CN113004373B (zh) * 2019-12-19 2024-08-13 鲁南制药集团股份有限公司 一种达托霉素的纯化方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331594A (en) 1978-10-16 1982-05-25 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4208403A (en) 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4537717A (en) 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
CN1051200A (zh) 1984-10-09 1991-05-08 伊莱利利公司 制备抗菌素a-21978c复合物或因子的方法
US4885243A (en) 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
US4885157A (en) 1987-02-13 1989-12-05 Fiaschetti Mary G Dermal cosmetic composition and applications therefor
ZA883887B (en) 1987-06-10 1990-02-28 Lilly Co Eli Chromatographic purification process
US4874843A (en) 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US6716962B2 (en) 2000-07-17 2004-04-06 Micrologix Biotech Inc. Extractive purification of lipopeptide antibiotics
US20030045484A1 (en) 2000-12-18 2003-03-06 Dennis Keith Methods for preparing purified daptomycin
KR100554481B1 (ko) * 2004-06-30 2006-03-03 씨제이 주식회사 반코마이신 염산염의 정제방법
WO2009144739A1 (fr) * 2008-05-26 2009-12-03 Biocon Limited Daptomycine amorphe et son procédé de purification
DK2149609T3 (da) 2008-08-01 2011-05-16 Olon Spa Forbedret fremgangsmåde til fremstilling af daptomycin
CN102325787B (zh) * 2008-12-22 2014-05-28 丘比斯特药物股份有限公司 治疗革兰氏阳性感染的新的抗菌剂
PL2398817T5 (pl) 2009-02-19 2021-10-04 Xellia Pharmaceuticals Aps Sposób oczyszczania lipopeptydów
CN101899094B (zh) * 2009-06-01 2012-11-21 安徽丰原发酵技术工程研究有限公司 一种高纯达托霉素的制备方法

Also Published As

Publication number Publication date
BR112019012273A2 (pt) 2019-12-03
US20210355160A1 (en) 2021-11-18
EP3555114A1 (fr) 2019-10-23
PH12019501183A1 (en) 2020-01-20
IT201600127655A1 (it) 2018-06-16
CA3045214A1 (fr) 2018-06-21
WO2018108896A1 (fr) 2018-06-21
MX2019007072A (es) 2019-08-01
AU2017376192A1 (en) 2019-07-11

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