MA47014A - Procédé de purification d'antibiotiques lipopeptidiques - Google Patents

Procédé de purification d'antibiotiques lipopeptidiques

Info

Publication number
MA47014A
MA47014A MA047014A MA47014A MA47014A MA 47014 A MA47014 A MA 47014A MA 047014 A MA047014 A MA 047014A MA 47014 A MA47014 A MA 47014A MA 47014 A MA47014 A MA 47014A
Authority
MA
Morocco
Prior art keywords
lipopeptidic
antibiotics
purification process
purification
lipopeptidic antibiotics
Prior art date
Application number
MA047014A
Other languages
English (en)
Inventor
Mauro Rossini
Auro Roberto Tagliani
Ermanno Valoti
Original Assignee
Gnosis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Spa filed Critical Gnosis Spa
Publication of MA47014A publication Critical patent/MA47014A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA047014A 2016-12-16 2017-12-12 Procédé de purification d'antibiotiques lipopeptidiques MA47014A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000127655A IT201600127655A1 (it) 2016-12-16 2016-12-16 Processo per la purificazione di antibiotici lipopolipeptidici

Publications (1)

Publication Number Publication Date
MA47014A true MA47014A (fr) 2019-10-23

Family

ID=58545105

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047014A MA47014A (fr) 2016-12-16 2017-12-12 Procédé de purification d'antibiotiques lipopeptidiques

Country Status (10)

Country Link
US (1) US20210355160A1 (fr)
EP (1) EP3555114A1 (fr)
AU (1) AU2017376192A1 (fr)
BR (1) BR112019012273A2 (fr)
CA (1) CA3045214A1 (fr)
IT (1) IT201600127655A1 (fr)
MA (1) MA47014A (fr)
MX (1) MX2019007072A (fr)
PH (1) PH12019501183A1 (fr)
WO (1) WO2018108896A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800006314A1 (it) * 2018-06-14 2019-12-14 Uso di resine a scambio cationico per la purificazione di antibiotici lipopolipeptidici
CN113004373B (zh) * 2019-12-19 2024-08-13 鲁南制药集团股份有限公司 一种达托霉素的纯化方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208403A (en) 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4331594A (en) 1978-10-16 1982-05-25 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4537717A (en) 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4885243A (en) 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
DD238068A5 (de) 1984-10-09 1986-08-06 ���@�����@�K@�������k�� Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c
US4885157A (en) 1987-02-13 1989-12-05 Fiaschetti Mary G Dermal cosmetic composition and applications therefor
US4874843A (en) 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
CA1315229C (fr) 1987-06-10 1993-03-30 Eli Lilly And Company Procede de purification chromatographique
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US6716962B2 (en) 2000-07-17 2004-04-06 Micrologix Biotech Inc. Extractive purification of lipopeptide antibiotics
KR20090122469A (ko) 2000-12-18 2009-11-30 큐비스트 파마슈티컬즈 인코포레이티드 정제된 리포펩티드의 제조 방법
KR100554481B1 (ko) * 2004-06-30 2006-03-03 씨제이 주식회사 반코마이신 염산염의 정제방법
WO2009144739A1 (fr) * 2008-05-26 2009-12-03 Biocon Limited Daptomycine amorphe et son procédé de purification
PT2149609E (pt) 2008-08-01 2011-04-14 Olon Spa Processo melhorado para a produção de daptomicina
DK2379580T3 (da) * 2008-12-22 2014-01-20 Cubist Pharm Inc Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner
KR101666144B1 (ko) 2009-02-19 2016-10-13 셀리아 파마슈티칼즈 에이피에스 리포펩티드를 정제하는 방법
CN101899094B (zh) * 2009-06-01 2012-11-21 安徽丰原发酵技术工程研究有限公司 一种高纯达托霉素的制备方法

Also Published As

Publication number Publication date
EP3555114A1 (fr) 2019-10-23
CA3045214A1 (fr) 2018-06-21
WO2018108896A1 (fr) 2018-06-21
US20210355160A1 (en) 2021-11-18
AU2017376192A1 (en) 2019-07-11
IT201600127655A1 (it) 2018-06-16
BR112019012273A2 (pt) 2019-12-03
PH12019501183A1 (en) 2020-01-20
MX2019007072A (es) 2019-08-01

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