MA47381A - Procédés et micro-organismes de fabrication de 2,3-butanediol et ses dérivés à partir de composés carbonés en c1 - Google Patents

Procédés et micro-organismes de fabrication de 2,3-butanediol et ses dérivés à partir de composés carbonés en c1

Info

Publication number: MA47381A
Authority: MA; Morocco
Prior art keywords: butanediol; organisms; derivatives; micro; manufacture
Prior art date: 2017-01-30

Application number

MA047381A

Other languages

English (en)

Inventor

Lily Yuin Chao

Kevin Lee Dietzel

Mark Anton Held

Tina Huynh

James Kealey

Matthias Helmut Schamlisch

Na Trinh

Bryan Yeh

Xinhua Zhao

Original Assignee

Intrexon Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-01-30

Filing date

2018-01-30

Publication date

2021-04-14

2018-01-30 Application filed by Intrexon Corp filed Critical Intrexon Corp

2021-04-14 Publication of MA47381A publication Critical patent/MA47381A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C11/00—Aliphatic unsaturated hydrocarbons
- C07C11/12—Alkadienes
- C07C11/16—Alkadienes with four carbon atoms
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/023—Methane
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01076—(S,S)-Butanediol dehydrogenase (1.1.1.76)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01304—Diacetyl reductase, (S)-acetoin forming (1.1.1.304)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01004—Acetoacetate decarboxylase (4.1.1.4)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01005—Acetolactate decarboxylase (4.1.1.5)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01004—R,R-butanediol dehydrogenase (1.1.1.4)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01006—Acetolactate synthase (2.2.1.6)
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Biophysics (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

MA047381A 2017-01-30 2018-01-30 Procédés et micro-organismes de fabrication de 2,3-butanediol et ses dérivés à partir de composés carbonés en c1 MA47381A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US201762451819P	2017-01-30	2017-01-30
US201762504626P	2017-05-11	2017-05-11
US201762512312P	2017-05-30	2017-05-30
US201762588985P	2017-11-21	2017-11-21

Publications (1)

Publication Number	Publication Date
MA47381A true MA47381A (fr)	2021-04-14

Family

ID=62978733

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA047381A MA47381A (fr)	2017-01-30	2018-01-30	Procédés et micro-organismes de fabrication de 2,3-butanediol et ses dérivés à partir de composés carbonés en c1

Country Status (14)

Country	Link
US (6)	US11198877B2 (fr)
EP (2)	EP3574092A4 (fr)
KR (2)	KR102525517B1 (fr)
CN (1)	CN110475850B (fr)
AU (2)	AU2018213387B2 (fr)
BR (1)	BR112019015754A2 (fr)
CA (2)	CA3052046A1 (fr)
IL (2)	IL268337B2 (fr)
MA (1)	MA47381A (fr)
MX (1)	MX2019009032A (fr)
PH (2)	PH12019501767A1 (fr)
SG (3)	SG10202107750TA (fr)
WO (2)	WO2018140936A1 (fr)
ZA (3)	ZA201905095B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA3059589A1 (fr)	2017-04-28	2018-11-01	Intrexon Corporation	Procedes et micro-organismes pour la fermentation de methane en composes multi-carbones
CN112154207B (zh) *	2018-08-24	2022-03-22	江苏省农业科学院	油菜抗嘧啶水杨酸类除草剂基因及其应用
KR102481504B1 (ko) *	2019-04-16	2022-12-27	경희대학교 산학협력단	2,3-부탄디올 생산용 메탄자화균 형질전환체
KR20210045752A (ko)	2019-10-17	2021-04-27	경희대학교 산학협력단	1,3-부탄다이올 생산용 형질전환 메탄자화균 및 이의 용도
CN114731793A (zh) *	2022-04-07	2022-07-12	中山大学	一种降低稻田土壤甲烷排放的方法
CN115058374B (zh) *	2022-05-24	2023-08-01	天津大学前沿技术研究院有限公司	一种利用丙酮酸合成乙偶姻的重组运动发酵单胞菌及其构建方法与应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1268823E (pt)	2000-03-24	2008-02-01	Xoma Technology Ltd	Métodos e células para expressão de produtos de proteínas recombinantes
EP2287179A3 (fr)	2004-01-09	2011-05-18	Novozymes A/S	Expression améliorée de Bacillus YweA
US8962298B2 (en)	2006-05-02	2015-02-24	Butamax Advanced Biofuels Llc	Recombinant host cell comprising a diol dehydratase
US20080014619A1 (en)	2006-07-12	2008-01-17	Lixuan Lisa Huang	Method of production of para-hydroxycinnamic acid
EP2285948B1 (fr) *	2008-03-03	2014-01-08	Joule Unlimited Technologies, Inc.	Microorganismes de synthèse fixant le co2 et produisant des produits carbonés d intérêt
WO2013102147A2 (fr)	2011-12-30	2013-07-04	Butamax (Tm) Advanced Biofuels Llc	Interrupteurs génétiques utilisables en vue de la production de butanol
WO2014089436A1 (fr) *	2012-12-07	2014-06-12	Ginkgo Bioworks, Inc.	Procédés et systèmes de production méthylotrophique de composés organiques
WO2014092562A1 (fr)	2012-12-11	2014-06-19	Photanol B.V.	Synthèse d'acétoïne, de 2,3-butanediol et de 2-butanol par des cyanobactéries par expression hétérologue d'une voie catabolique
US9267158B2 (en) *	2013-03-14	2016-02-23	Intrexon Corporation	Biological production of multi-carbon compounds from methane
EP3158065B1 (fr)	2014-06-18	2019-01-09	Calysta, Inc.	Acides nucléique et vecteurs destinés à être utilisés avec des bactéries méthanotrophes
WO2016094334A1 (fr)	2014-12-08	2016-06-16	Lanzatech New Zealand Limited	Micro-organismes recombinés présentant un flux accru par un voie de fermentation
US10858661B2 (en) *	2017-01-10	2020-12-08	University-Industry Cooperation Group Of Kyung Hee University	Use of Methylomonas sp. DH-1 strain and its transformants
CA3059589A1 (fr) *	2017-04-28	2018-11-01	Intrexon Corporation	Procedes et micro-organismes pour la fermentation de methane en composes multi-carbones

2018
- 2018-01-30 CA CA3052046A patent/CA3052046A1/fr active Pending
- 2018-01-30 KR KR1020197024829A patent/KR102525517B1/ko active Active
- 2018-01-30 SG SG10202107750TA patent/SG10202107750TA/en unknown
- 2018-01-30 EP EP18745386.5A patent/EP3574092A4/fr active Pending
- 2018-01-30 AU AU2018213387A patent/AU2018213387B2/en active Active
- 2018-01-30 WO PCT/US2018/015925 patent/WO2018140936A1/fr not_active Ceased
- 2018-01-30 KR KR1020237013483A patent/KR20230142696A/ko not_active Ceased
- 2018-01-30 CN CN201880023046.1A patent/CN110475850B/zh active Active
- 2018-01-30 MX MX2019009032A patent/MX2019009032A/es unknown
- 2018-01-30 WO PCT/US2018/015909 patent/WO2018140928A1/fr not_active Ceased
- 2018-01-30 AU AU2018213395A patent/AU2018213395B2/en active Active
- 2018-01-30 BR BR112019015754A patent/BR112019015754A2/pt not_active Application Discontinuation
- 2018-01-30 US US16/481,811 patent/US11198877B2/en active Active
- 2018-01-30 CA CA3052072A patent/CA3052072A1/fr active Pending
- 2018-01-30 EP EP18744512.7A patent/EP3574081A4/fr active Pending
- 2018-01-30 SG SG11201907012VA patent/SG11201907012VA/en unknown
- 2018-01-30 SG SG11201907008RA patent/SG11201907008RA/en unknown
- 2018-01-30 US US16/481,799 patent/US11111496B2/en active Active
- 2018-01-30 MA MA047381A patent/MA47381A/fr unknown
- 2018-01-30 IL IL268337A patent/IL268337B2/en unknown
2019
- 2019-07-29 IL IL268339A patent/IL268339A/en unknown
- 2019-07-30 PH PH12019501767A patent/PH12019501767A1/en unknown
- 2019-07-30 PH PH12019501768A patent/PH12019501768A1/en unknown
- 2019-07-31 ZA ZA2019/05095A patent/ZA201905095B/en unknown
- 2019-07-31 ZA ZA2019/05094A patent/ZA201905094B/en unknown
2021
- 2021-07-30 ZA ZA2021/05423A patent/ZA202105423B/en unknown
- 2021-07-31 US US17/444,188 patent/US11939584B2/en active Active
- 2021-11-08 US US17/454,060 patent/US12091667B2/en active Active
2024
- 2024-02-20 US US18/582,362 patent/US20240263182A1/en active Pending
- 2024-08-14 US US18/805,099 patent/US20250027093A1/en active Pending

Also Published As

Publication number	Publication date
RU2019124480A3 (fr)	2021-12-15
ZA201905094B (en)	2022-01-26
WO2018140928A1 (fr)	2018-08-02
ZA202105423B (en)	2023-12-20
SG10202107750TA (en)	2021-09-29
PH12019501767A1 (en)	2020-06-01
WO2018140936A1 (fr)	2018-08-02
AU2018213395B2 (en)	2024-09-05
CA3052072A1 (fr)	2018-08-02
KR20230142696A (ko)	2023-10-11
CA3052046A1 (fr)	2018-08-02
ZA201905095B (en)	2022-12-21
US20250027093A1 (en)	2025-01-23
AU2018213387A1 (en)	2019-08-15
CN110475850B (zh)	2023-11-07
MX2019009032A (es)	2019-09-10
US20220112506A1 (en)	2022-04-14
KR102525517B1 (ko)	2023-04-25
BR112019015754A2 (pt)	2020-06-09
IL268337B1 (en)	2024-05-01
PH12019501768A1 (en)	2020-03-16
EP3574092A4 (fr)	2021-01-13
EP3574081A4 (fr)	2021-04-14
IL268337B2 (en)	2024-09-01
US20240263182A1 (en)	2024-08-08
US20220049259A1 (en)	2022-02-17
KR20190112044A (ko)	2019-10-02
EP3574081A1 (fr)	2019-12-04
US11111496B2 (en)	2021-09-07
US12091667B2 (en)	2024-09-17
CN110475850A (zh)	2019-11-19
IL268339A (en)	2019-09-26
RU2019124480A (ru)	2021-03-01
EP3574092A1 (fr)	2019-12-04
SG11201907012VA (en)	2019-08-27
AU2018213395A1 (en)	2019-08-15
US11939584B2 (en)	2024-03-26
US11198877B2 (en)	2021-12-14
AU2018213387B2 (en)	2024-06-13
IL268337A (en)	2019-09-26
SG11201907008RA (en)	2019-08-27
US20200115713A1 (en)	2020-04-16
US20200040344A1 (en)	2020-02-06

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