MA47416A - Protéine de fusion du facteur ix et procédés de fabrication et d'utilisation associés - Google Patents

Protéine de fusion du facteur ix et procédés de fabrication et d'utilisation associés

Info

Publication number
MA47416A
MA47416A MA047416A MA47416A MA47416A MA 47416 A MA47416 A MA 47416A MA 047416 A MA047416 A MA 047416A MA 47416 A MA47416 A MA 47416A MA 47416 A MA47416 A MA 47416A
Authority
MA
Morocco
Prior art keywords
factor
fusion protein
use processes
related manufacturing
manufacturing
Prior art date
Application number
MA047416A
Other languages
English (en)
Inventor
Ekta Seth Chhabra
Ayman Ismail
John Kulman
David R Light
Tongyao Liu
Zhiqian Liu
Robert T Peters
Der Flier Arjan Van
Original Assignee
Bioverativ Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Therapeutics Inc filed Critical Bioverativ Therapeutics Inc
Publication of MA47416A publication Critical patent/MA47416A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA047416A 2017-01-31 2018-01-31 Protéine de fusion du facteur ix et procédés de fabrication et d'utilisation associés MA47416A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762452826P 2017-01-31 2017-01-31

Publications (1)

Publication Number Publication Date
MA47416A true MA47416A (fr) 2019-12-11

Family

ID=61193175

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047416A MA47416A (fr) 2017-01-31 2018-01-31 Protéine de fusion du facteur ix et procédés de fabrication et d'utilisation associés

Country Status (19)

Country Link
US (1) US20210238259A1 (fr)
EP (1) EP3576762A1 (fr)
JP (1) JP2020505424A (fr)
KR (1) KR20190112763A (fr)
CN (1) CN110831613A (fr)
AR (1) AR110871A1 (fr)
AU (1) AU2018215092A1 (fr)
BR (1) BR112019015569A2 (fr)
CA (1) CA3051862A1 (fr)
CL (1) CL2019002155A1 (fr)
CR (1) CR20190389A (fr)
EA (1) EA201991768A1 (fr)
IL (1) IL268234A (fr)
MA (1) MA47416A (fr)
MX (1) MX2019009063A (fr)
PH (1) PH12019501765A1 (fr)
SG (1) SG11201906788XA (fr)
TW (1) TW201831521A (fr)
WO (1) WO2018144623A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
CN112175088B (zh) * 2019-07-02 2023-03-28 江苏晟斯生物制药有限公司 改进的fix融合蛋白、缀合物及其应用
CN113817759B (zh) * 2020-07-10 2023-06-02 南京吉迈生物技术有限公司 修饰的因子ix、组合物、方法及其在基因治疗中的应用

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Also Published As

Publication number Publication date
AR110871A1 (es) 2019-05-08
MX2019009063A (es) 2019-10-21
EP3576762A1 (fr) 2019-12-11
KR20190112763A (ko) 2019-10-07
EA201991768A1 (ru) 2020-01-22
CA3051862A1 (fr) 2018-08-09
US20210238259A1 (en) 2021-08-05
PH12019501765A1 (en) 2020-03-16
AU2018215092A1 (en) 2019-08-29
WO2018144623A1 (fr) 2018-08-09
CN110831613A (zh) 2020-02-21
CL2019002155A1 (es) 2020-02-21
TW201831521A (zh) 2018-09-01
IL268234A (en) 2019-09-26
BR112019015569A2 (pt) 2020-03-17
JP2020505424A (ja) 2020-02-20
CR20190389A (es) 2019-11-26
SG11201906788XA (en) 2019-08-27

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