MA48448A - Dérivés de quinazoline utilisés pour traiter le vih - Google Patents

Dérivés de quinazoline utilisés pour traiter le vih

Info

Publication number: MA48448A
Authority: MA; Morocco
Prior art keywords: derivatives used; quinazoline derivatives; treat hiv; hiv; treat
Prior art date: 2014-12-24

Application number

MA048448A

Other languages

English (en)

Inventor

Ondrej Baszczynski

Milan Dejmek

Yunfeng Eric Hu

Petr Jansa

Eric Lansdon

Richard L Mackman

Petr Simon

Original Assignee

Gilead Sciences Inc

Inst Of Organic Chemistry And Biochemistry As Cr V V I

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-12-24

Filing date

2015-12-23

Publication date

2021-04-28

2015-12-23 Application filed by Gilead Sciences Inc, Inst Of Organic Chemistry And Biochemistry As Cr V V I filed Critical Gilead Sciences Inc

2021-04-28 Publication of MA48448A publication Critical patent/MA48448A/fr

Links

JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

MA048448A 2014-12-24 2015-12-23 Dérivés de quinazoline utilisés pour traiter le vih MA48448A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201462096748P	2014-12-24	2014-12-24

Publications (1)

Publication Number	Publication Date
MA48448A true MA48448A (fr)	2021-04-28

Family

ID=55305044

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA048448A MA48448A (fr)	2014-12-24	2015-12-23	Dérivés de quinazoline utilisés pour traiter le vih

Country Status (41)

Country	Link
US (5)	US9730936B2 (fr)
EP (4)	EP3521282B1 (fr)
JP (2)	JP6367489B2 (fr)
KR (2)	KR102049476B1 (fr)
CN (2)	CN107278201B (fr)
AR (1)	AR103252A1 (fr)
AU (1)	AU2015371198B2 (fr)
BR (1)	BR102015032361B1 (fr)
CA (1)	CA2972021C (fr)
CL (1)	CL2017001675A1 (fr)
CO (1)	CO2017006214A2 (fr)
CR (1)	CR20170281A (fr)
CU (1)	CU20170089A7 (fr)
CY (1)	CY1124726T1 (fr)
DK (1)	DK3521282T3 (fr)
DO (1)	DOP2017000151A (fr)
EA (2)	EA035746B1 (fr)
EC (1)	ECSP17039611A (fr)
ES (3)	ES2964395T3 (fr)
HK (1)	HK1244001B (fr)
HR (1)	HRP20211543T1 (fr)
HU (1)	HUE058296T2 (fr)
IL (2)	IL253059B (fr)
LT (1)	LT3521282T (fr)
MA (1)	MA48448A (fr)
MD (1)	MD4650B1 (fr)
MX (2)	MX367574B (fr)
MY (1)	MY189761A (fr)
NZ (1)	NZ733174A (fr)
PE (1)	PE20171306A1 (fr)
PH (1)	PH12017501191B1 (fr)
PL (3)	PL3237398T3 (fr)
PT (2)	PT3237398T (fr)
SA (1)	SA517381826B1 (fr)
SG (2)	SG10202101143VA (fr)
SI (2)	SI3237398T1 (fr)
SV (1)	SV2017005471A (fr)
TR (1)	TR201903672T4 (fr)
TW (3)	TWI770552B (fr)
UA (1)	UA117796C2 (fr)
WO (1)	WO2016105564A1 (fr)

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2015
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Publication number	Publication date
TW202237569A (zh)	2022-10-01
BR102015032361B1 (pt)	2021-12-21
AU2015371198A1 (en)	2017-07-13
HUE058296T2 (hu)	2022-07-28
MX2019009932A (es)	2019-10-02
NZ733174A (en)	2018-12-21
PE20171306A1 (es)	2017-09-05
ES2964395T3 (es)	2024-04-05
PL3521282T3 (pl)	2022-01-03
SI3237398T1 (sl)	2019-04-30
CR20170281A (es)	2017-11-08
TWI770552B (zh)	2022-07-11
IL269635B (en)	2021-04-29
EP4302830A3 (fr)	2024-03-13
EP3960735A1 (fr)	2022-03-02
EP3960735B1 (fr)	2023-09-13
PT3521282T (pt)	2021-11-29
JP6367489B2 (ja)	2018-08-01
EA201791256A1 (ru)	2018-04-30
MD20170070A2 (ro)	2017-12-31
HRP20211543T1 (hr)	2022-01-07
ES2715507T3 (es)	2019-06-04
HK1244001B (en)	2020-01-10
CN107278201B (zh)	2020-05-19
EA202091115A1 (ru)	2021-01-29
UA117796C2 (uk)	2018-09-25
SI3521282T1 (sl)	2021-11-30
MX2017008521A (es)	2018-03-01
CA2972021C (fr)	2020-04-28
CA2972021A1 (fr)	2016-06-30
MX367574B (es)	2019-08-27
PH12017501191B1 (en)	2021-08-06
CL2017001675A1 (es)	2018-05-11
EP3960735C0 (fr)	2023-09-13
BR102015032361A8 (pt)	2021-08-31
US11304948B2 (en)	2022-04-19
SG10202101143VA (en)	2021-03-30
CY1124726T1 (el)	2022-07-22
US20200360383A1 (en)	2020-11-19
WO2016105564A1 (fr)	2016-06-30
CN111574464A (zh)	2020-08-25
EP4302830A2 (fr)	2024-01-10
CN107278201A (zh)	2017-10-20
EP3237398A1 (fr)	2017-11-01
US10548898B2 (en)	2020-02-04
WO2016105564A8 (fr)	2016-10-06
PH12017501191A1 (en)	2018-03-05
SA517381826B1 (ar)	2021-10-21
KR102049476B1 (ko)	2019-11-28
KR102288855B1 (ko)	2021-08-11
LT3521282T (lt)	2021-11-25
AU2015371198B2 (en)	2018-09-27
JP2018500358A (ja)	2018-01-11
KR20170131351A (ko)	2017-11-29
TW201636328A (zh)	2016-10-16
CO2017006214A2 (es)	2017-10-20
MD4650B1 (ro)	2019-09-30
TWI699355B (zh)	2020-07-21
US10206926B2 (en)	2019-02-19
IL253059A0 (en)	2017-08-31
PL3960735T3 (pl)	2024-03-18
US20170354656A1 (en)	2017-12-14
US20160250215A1 (en)	2016-09-01
IL253059B (en)	2019-10-31
JP2018168181A (ja)	2018-11-01
EP3521282B1 (fr)	2021-08-25
KR20190133068A (ko)	2019-11-29
PT3237398T (pt)	2019-03-06
CU20170089A7 (es)	2017-11-07
US20190134035A1 (en)	2019-05-09
EA035746B1 (ru)	2020-08-05
DOP2017000151A (es)	2017-09-15
DK3521282T3 (da)	2021-09-27
US20230043136A1 (en)	2023-02-09
TW202106667A (zh)	2021-02-16
SG11201705215PA (en)	2017-07-28
IL269635A (en)	2019-11-28
ECSP17039611A (es)	2017-07-31
EP3237398B1 (fr)	2018-12-19
ES2900810T3 (es)	2022-03-18
US9730936B2 (en)	2017-08-15
MY189761A (en)	2022-03-03
AR103252A1 (es)	2017-04-26
SV2017005471A (es)	2018-01-18
TR201903672T4 (tr)	2019-04-22
EP3521282A1 (fr)	2019-08-07
PL3237398T3 (pl)	2019-05-31
BR102015032361A2 (pt)	2016-07-05

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