MA48798A - Procédé de production d'ozanimod - Google Patents
Procédé de production d'ozanimodInfo
- Publication number
- MA48798A MA48798A MA048798A MA48798A MA48798A MA 48798 A MA48798 A MA 48798A MA 048798 A MA048798 A MA 048798A MA 48798 A MA48798 A MA 48798A MA 48798 A MA48798 A MA 48798A
- Authority
- MA
- Morocco
- Prior art keywords
- ozanimod
- production process
- production
- ozanimod production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUP1700216 | 2017-05-22 | ||
| PCT/HU2018/050019 WO2018215807A1 (fr) | 2017-05-22 | 2018-05-18 | Procédé de production d'ozanimod |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA48798A true MA48798A (fr) | 2020-04-08 |
| MA48798B1 MA48798B1 (fr) | 2023-10-31 |
Family
ID=89720175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA48798A MA48798B1 (fr) | 2017-05-22 | 2018-05-18 | Procédé de production d'ozanimod |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12459907B2 (fr) |
| EP (1) | EP3630738B1 (fr) |
| CN (1) | CN110997645B (fr) |
| EA (1) | EA201992421A1 (fr) |
| ES (1) | ES2960051T3 (fr) |
| HR (1) | HRP20231308T1 (fr) |
| HU (1) | HUE064642T2 (fr) |
| MA (1) | MA48798B1 (fr) |
| PL (1) | PL3630738T3 (fr) |
| PT (1) | PT3630738T (fr) |
| SI (1) | SI3630738T1 (fr) |
| WO (1) | WO2018215807A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019094409A1 (fr) * | 2017-11-07 | 2019-05-16 | Teva Pharmaceuticals International Gmbh | Sels et formes à l'état solide d'ozanimod |
| EP3891133B1 (fr) | 2018-12-07 | 2023-06-07 | Synthon B.V. | Procédé amélioré pour la préparation d'ozanimod |
| WO2020152718A1 (fr) * | 2019-01-25 | 2020-07-30 | Mylan Laboratories Limited | Formes polymorphes de 5-[3-[(1s)-2,3-dihydro-1-[(2-hydroxyéthyl) amino]-1h-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-méthyléthoxy)benzonitrile |
| CN112062785B (zh) * | 2019-06-11 | 2023-06-27 | 广东东阳光药业有限公司 | 奥扎莫德及其中间体的制备方法 |
| MX2022000651A (es) | 2019-07-16 | 2022-03-11 | Synthon Bv | Proceso mejorado para preparar ozanimod. |
| TW202131921A (zh) | 2019-10-31 | 2021-09-01 | 瑞士商愛杜西亞製藥有限公司 | Cxcr7拮抗劑與s1p1受體調節劑之組合 |
| EP4126826A1 (fr) * | 2020-04-02 | 2023-02-08 | Synthon B.V. | Forme cristalline d'hydrochlorure d'ozanimod |
| EP4212156A1 (fr) | 2022-01-13 | 2023-07-19 | Abivax | Combinaison de 8-chloro-n-(4-(trifluorométhoxy)phényl)quinolin-2-amine et de ses dérivés avec un modulateur de récepteur de s1p |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012007635B1 (pt) | 2009-10-08 | 2019-07-09 | Sanofi | Compostos derivados de feniloxadiazol como inibidores de pgds, composição farmacêutica compreendendo os mesmos e seus processos de preparação |
| SI2498610T2 (sl) | 2009-11-13 | 2024-10-30 | Receptos Llc | Selektivni modulatorji receptorja sfingozin-1-fosfata in postopki kiralne sinteze |
| WO2015066515A1 (fr) * | 2013-11-01 | 2015-05-07 | Receptos, Inc. | Modulateurs sélectifs des récepteurs de la sphingosine-1-phosphate et traitement combiné les utilisant |
| FI3470400T3 (fi) | 2016-06-14 | 2025-06-13 | Receptos Llc | Otsanimodin kidemuoto, sen hydrokloridin kidemuoto ja niiden valmistusmenetelmä |
| US11028060B2 (en) * | 2016-08-19 | 2021-06-08 | Receptos Llc | Crystalline forms of ozanimod and processes for preparation thereof |
| US11117875B2 (en) | 2016-09-14 | 2021-09-14 | Hangzhou Solipharma Co., Ltd. | Crystalline forms, preparation methods and pharmaceutical compositions of ozanimod |
| EP3518922B1 (fr) * | 2016-09-29 | 2026-02-11 | Receptos LLC | Composés et méthodes de traitement du lupus |
-
2018
- 2018-05-18 EP EP18806925.6A patent/EP3630738B1/fr active Active
- 2018-05-18 CN CN201880049683.6A patent/CN110997645B/zh active Active
- 2018-05-18 PT PT188069256T patent/PT3630738T/pt unknown
- 2018-05-18 EA EA201992421A patent/EA201992421A1/ru unknown
- 2018-05-18 HR HRP20231308TT patent/HRP20231308T1/hr unknown
- 2018-05-18 SI SI201831007T patent/SI3630738T1/sl unknown
- 2018-05-18 HU HUE18806925A patent/HUE064642T2/hu unknown
- 2018-05-18 WO PCT/HU2018/050019 patent/WO2018215807A1/fr not_active Ceased
- 2018-05-18 US US16/615,468 patent/US12459907B2/en active Active
- 2018-05-18 ES ES18806925T patent/ES2960051T3/es active Active
- 2018-05-18 MA MA48798A patent/MA48798B1/fr unknown
- 2018-05-18 PL PL18806925.6T patent/PL3630738T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2960051T3 (es) | 2024-02-29 |
| WO2018215807A1 (fr) | 2018-11-29 |
| EP3630738B1 (fr) | 2023-07-19 |
| CN110997645A (zh) | 2020-04-10 |
| MA48798B1 (fr) | 2023-10-31 |
| SI3630738T1 (sl) | 2024-02-29 |
| PL3630738T3 (pl) | 2024-04-08 |
| HUE064642T2 (hu) | 2024-04-28 |
| EP3630738A4 (fr) | 2021-03-10 |
| PT3630738T (pt) | 2023-10-24 |
| US20200087269A1 (en) | 2020-03-19 |
| EP3630738A1 (fr) | 2020-04-08 |
| US12459907B2 (en) | 2025-11-04 |
| CN110997645B (zh) | 2023-10-10 |
| HRP20231308T1 (hr) | 2024-04-26 |
| EA201992421A1 (ru) | 2020-03-27 |
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