MA49059A - Traitement des cancers positifs à her2 - Google Patents

Traitement des cancers positifs à her2

Info

Publication number
MA49059A
MA49059A MA049059A MA49059A MA49059A MA 49059 A MA49059 A MA 49059A MA 049059 A MA049059 A MA 049059A MA 49059 A MA49059 A MA 49059A MA 49059 A MA49059 A MA 49059A
Authority
MA
Morocco
Prior art keywords
treatment
positive her2
cancers
her2 cancers
positive
Prior art date
Application number
MA049059A
Other languages
English (en)
Inventor
Scott Peterson
Luke Walker
Original Assignee
Seagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seagen Inc filed Critical Seagen Inc
Publication of MA49059A publication Critical patent/MA49059A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA049059A 2017-04-28 2018-04-27 Traitement des cancers positifs à her2 MA49059A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762491872P 2017-04-28 2017-04-28

Publications (1)

Publication Number Publication Date
MA49059A true MA49059A (fr) 2021-03-24

Family

ID=62165692

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049059A MA49059A (fr) 2017-04-28 2018-04-27 Traitement des cancers positifs à her2

Country Status (13)

Country Link
US (3) US11207324B2 (fr)
EP (1) EP3615067A1 (fr)
JP (2) JP7328151B2 (fr)
KR (1) KR102845148B1 (fr)
CN (1) CN111032082B (fr)
AU (2) AU2018258663B2 (fr)
BR (1) BR112019022280A2 (fr)
CA (1) CA3060407A1 (fr)
EA (1) EA201992573A1 (fr)
MA (1) MA49059A (fr)
SG (1) SG11201909676WA (fr)
WO (1) WO2018201016A1 (fr)
ZA (1) ZA201907225B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018201016A1 (fr) 2017-04-28 2018-11-01 Cascadian Therapeutics, Inc. Traitement des cancers positifs à her2
TW202042820A (zh) * 2019-01-28 2020-12-01 美商西雅圖遺傳學股份有限公司 以妥卡替尼(Tucatinib)治療乳癌之方法
AU2019450366B2 (en) * 2019-06-11 2026-01-08 Board Of Regents, The University Of Texas System Use of an RXR agonist in treating Her2+ cancers
MX2022004699A (es) * 2019-10-21 2022-08-08 Seagen Inc Metodos de tratamiento del cancer de mama con sobreexpresion de her2 con tucatinib en combinacion con capecitabina y trastuzumab.
EP4058024A1 (fr) * 2019-11-15 2022-09-21 Seagen Inc. Méthodes de traitement du cancer du sein her2 positif avec du tucatinib en combinaison avec un conjugué médicament-anticorps anti-her2
US20230173067A1 (en) * 2020-05-29 2023-06-08 Seagen Inc. Methods of treating her2 positive cancer with tucatinib in combination with trastuzumab and an oxaliplatin-based chemotherapy
KR20230047359A (ko) * 2020-07-29 2023-04-07 시아겐 인크. 트라스투주맙, 탁산 및 vegfr-2 길항제와 병용하여 투카티닙을 이용하는 her2 양성 암의 치료 방법
AU2021349384A1 (en) * 2020-09-28 2023-05-25 Seagen Inc. Methods of treating solid tumors driven by her2 alterations with tucatinib in combination with an anti-her2 antibody
IL303350A (en) 2020-12-04 2023-08-01 Macrogenics Inc Pharmaceutical compositions of a her2/neu antibody and use of the same
US11526994B1 (en) * 2021-09-10 2022-12-13 Neosoma, Inc. Labeling, visualization, and volumetric quantification of high-grade brain glioma from MRI images
WO2024183622A1 (fr) * 2023-03-03 2024-09-12 盛禾(中国)生物制药有限公司 Utilisation d'un anticorps anti-her2 dans la préparation d'un médicament pour le traitement du cancer
US20250228858A1 (en) 2023-12-20 2025-07-17 Boehringer Ingelheim International Gmbh Anti-cancer combination therapy

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4957735A (en) 1984-06-12 1990-09-18 The University Of Tennessee Research Corporation Target-sensitive immunoliposomes- preparation and characterization
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4902505A (en) 1986-07-30 1990-02-20 Alkermes Chimeric peptides for neuropeptide delivery through the blood-brain barrier
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5004697A (en) 1987-08-17 1991-04-02 Univ. Of Ca Cationized antibodies for delivery through the blood-brain barrier
US5055303A (en) 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
US5271961A (en) 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
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US5268164A (en) 1990-04-23 1993-12-07 Alkermes, Inc. Increasing blood-brain barrier permeability with permeabilizer peptides
US5254342A (en) 1991-09-30 1993-10-19 University Of Southern California Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
EP0630234B1 (fr) 1992-03-12 1997-06-11 Alkermes Controlled Therapeutics, Inc. Microspheres a liberation regulee contenant l'hormone adrenocorticotrope (acth)
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US5514670A (en) 1993-08-13 1996-05-07 Pharmos Corporation Submicron emulsions for delivery of peptides
US6350786B1 (en) 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
JP4828421B2 (ja) 2003-08-14 2011-11-30 アレイ バイオファーマ、インコーポレイテッド 受容体チロシンキナーゼ阻害剤としてのキナゾリン誘導体
AU2005251722B2 (en) 2004-06-03 2009-11-12 Smithkline Beecham (Cork) Limited Cancer treatment method
CA2755268C (fr) 2005-11-15 2013-12-31 Array Biopharma, Inc. Inhibiteurs erbb
WO2009042618A1 (fr) 2007-09-24 2009-04-02 Tragara Pharmaceuticals, Inc. Thérapies pour traiter le cancer en utilisant des combinaisons d'inhibiteurs de cox-2 et des anticorps anti-her2(erbb2) ou des combinaisons d'inhibiteurs de cox-2 et des inhibiteurs du récepteur her2(erbb2) de la tyrosine kinase
NZ587706A (en) 2008-03-18 2012-12-21 Genentech Inc Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
US20120295259A1 (en) * 2011-05-19 2012-11-22 Laboratory Corporation Of America Holdings Methods for Determining the Likelihood of Survival and for Predicting Likelihood of Metastasis in Cancer Patients
BR112012012160B1 (pt) * 2009-11-13 2022-04-26 Amgen, Inc. Material e métodos para tratar ou prevenir doenças associadas ao her-3
DK2765990T3 (da) 2011-10-14 2017-11-13 Array Biopharma Inc Faststofdispersion
RU2629116C2 (ru) 2011-10-14 2017-08-24 Эррэй Биофарма Инк. Полиморфы arry-380, селективного ингибитора erbb2, и фармацевтические составы, содержащие их
KR102317166B1 (ko) 2012-03-23 2021-10-26 어레이 바이오파마 인크. 뇌암의 치료
WO2016011328A1 (fr) * 2014-07-17 2016-01-21 Baker Cheryl Traitement du cancer associant un rayonnement, des nanoparticules d'oxyde de cérium et un agent chimiothérapeutique
EP3307728A4 (fr) * 2015-06-12 2019-07-17 Dana Farber Cancer Institute, Inc. Thérapie d'association utilisant des inhibiteurs de transcription et des inhibiteurs de kinases
EA201892368A1 (ru) * 2016-04-19 2019-05-31 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорниа ИНГИБИТОРЫ ErbB И ИХ ПРИМЕНЕНИЕ
WO2018201016A1 (fr) 2017-04-28 2018-11-01 Cascadian Therapeutics, Inc. Traitement des cancers positifs à her2
US20210239702A1 (en) 2018-06-14 2021-08-05 Memorial Sloan Kettering Cancer Center Methods for predicting responsiveness of lung cancer patients to her2-targeting therapies
TW202042820A (zh) 2019-01-28 2020-12-01 美商西雅圖遺傳學股份有限公司 以妥卡替尼(Tucatinib)治療乳癌之方法
MX2022004699A (es) 2019-10-21 2022-08-08 Seagen Inc Metodos de tratamiento del cancer de mama con sobreexpresion de her2 con tucatinib en combinacion con capecitabina y trastuzumab.
EP4058024A1 (fr) 2019-11-15 2022-09-21 Seagen Inc. Méthodes de traitement du cancer du sein her2 positif avec du tucatinib en combinaison avec un conjugué médicament-anticorps anti-her2
WO2021183529A1 (fr) 2020-03-11 2021-09-16 Seagen Inc. Procédés de traitement des cancers mutants her2 avec le tucatinib

Also Published As

Publication number Publication date
SG11201909676WA (en) 2019-11-28
US20220168303A1 (en) 2022-06-02
KR20200014298A (ko) 2020-02-10
AU2022241509B2 (en) 2025-02-20
US12048698B2 (en) 2024-07-30
WO2018201016A1 (fr) 2018-11-01
AU2018258663B2 (en) 2022-08-04
JP2020517696A (ja) 2020-06-18
CN111032082B (zh) 2025-01-07
AU2018258663A1 (en) 2019-11-14
CN111032082A (zh) 2020-04-17
ZA201907225B (en) 2023-11-29
EP3615067A1 (fr) 2020-03-04
AU2022241509A1 (en) 2022-10-27
JP2023145689A (ja) 2023-10-11
US11207324B2 (en) 2021-12-28
US20200188401A1 (en) 2020-06-18
EA201992573A1 (ru) 2020-04-06
BR112019022280A2 (pt) 2020-05-19
CA3060407A1 (fr) 2018-11-01
US20230390290A1 (en) 2023-12-07
KR102845148B1 (ko) 2025-08-20
JP7328151B2 (ja) 2023-08-16
US11666572B2 (en) 2023-06-06

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