MA49520A - Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés d'utilisation - Google Patents

Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés d'utilisation

Info

Publication number
MA49520A
MA49520A MA049520A MA49520A MA49520A MA 49520 A MA49520 A MA 49520A MA 049520 A MA049520 A MA 049520A MA 49520 A MA49520 A MA 49520A MA 49520 A MA49520 A MA 49520A
Authority
MA
Morocco
Prior art keywords
silk
methods
hyaluronic acid
tissue fillers
acid tissue
Prior art date
Application number
MA049520A
Other languages
English (en)
Inventor
Gregory H Altman
Erlei Jin
Peng Xu
Original Assignee
Evolved By Nature Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolved By Nature Inc filed Critical Evolved By Nature Inc
Publication of MA49520A publication Critical patent/MA49520A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA049520A 2017-06-26 2018-06-26 Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés d'utilisation MA49520A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762525131P 2017-06-26 2017-06-26
US201862641095P 2018-03-09 2018-03-09

Publications (1)

Publication Number Publication Date
MA49520A true MA49520A (fr) 2021-04-14

Family

ID=64742709

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049520A MA49520A (fr) 2017-06-26 2018-06-26 Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés d'utilisation

Country Status (14)

Country Link
US (1) US12611484B2 (fr)
EP (2) EP3645063B1 (fr)
JP (3) JP2020525253A (fr)
KR (1) KR20200032103A (fr)
CN (1) CN111263646A (fr)
AU (2) AU2018290810C1 (fr)
CA (1) CA3068296A1 (fr)
CO (1) CO2020000774A2 (fr)
ES (2) ES3018883T3 (fr)
IL (2) IL299584A (fr)
MA (1) MA49520A (fr)
SG (1) SG11201913229PA (fr)
UA (1) UA127350C2 (fr)
WO (1) WO2019005848A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201913229PA (en) 2017-06-26 2020-01-30 Evolved By Nature Inc Silk-hyaluronic acid based tissue fillers and methods of using the same
US20230190997A1 (en) 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
WO2019058483A1 (fr) 2017-09-21 2019-03-28 住友電気工業株式会社 Substrat de type cristal d'arséniure de gallium semi-isolant
WO2020132331A1 (fr) * 2018-12-19 2020-06-25 Evolved By Nature, Inc. Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés de préparation et d'utilisation
WO2020205774A1 (fr) * 2019-03-29 2020-10-08 Trustees Of Tufts College Compositions à base de fibroïnes de soie, ses procédés de préparation et ses méthodes d'utilisation
WO2020247887A1 (fr) * 2019-06-06 2020-12-10 Evolved By Nature, Inc. Production de collagène stimulée par la soie et procédés d'utilisation de celle-ci
WO2020262596A1 (fr) * 2019-06-26 2020-12-30 Compagnie Generale Des Etablissements Michelin Bande de roulement réduisant le bruit
CN110339398A (zh) * 2019-07-18 2019-10-18 王月玲 一种含氨基酸透明质酸钠注射剂及其制备方法
WO2021035087A1 (fr) * 2019-08-20 2021-02-25 Evolved By Nature, Inc. Compositions de soins personnels à base de soie
EP3995530B1 (fr) * 2019-09-27 2025-05-28 LG Chem, Ltd. Procédé de préparation de microparticules polymères, microparticules polymères, composition médicale, composition cosmétique, articles médicaux et articles cosmétiques les comprenant
EP4077402B1 (fr) * 2019-12-19 2024-05-01 Croma-Pharma GmbH Hyaluronane modifié par thiol et hydrogel comprenant l'hyaluronane réticulé
CN116507315A (zh) * 2020-06-19 2023-07-28 自然进化公司 用于组织填充、组织间隔和组织膨胀的丝-透明质酸组合物
CA3183134A1 (fr) * 2020-06-19 2021-12-23 Gregory H. Altman Compositions de soie-acide hyaluronique pour le remplissage tissulaire, l'espacement tissulaire et le gonflement tissulaire
JP2024519426A (ja) * 2020-09-29 2024-05-14 ジロパ・インコーポレイテッド 疼痛の緩和及び麻痺のための組成物及び方法
TR202101065A1 (tr) * 2021-01-25 2022-08-22 Hacettepe Ueniversitesi Hyaluroni̇k asi̇t jel i̇çeren bi̇r doku dolgu malzemesi̇ ve üreti̇m yöntemi̇
CN118909068A (zh) * 2021-02-08 2024-11-08 复向丝泰医疗科技(苏州)有限公司 利用切向流超滤技术制备可控高浓度丝素蛋白溶液的方法
WO2022246342A1 (fr) 2021-05-21 2022-11-24 Cambridge Crops, Inc. d/b/a Mori Systèmes et procédés de fabrication d'une solution de fibroïne de soie et poudres contenant de la fibroïne de soie
WO2023275278A1 (fr) * 2021-06-30 2023-01-05 Merz Pharma Gmbh & Co. Kgaa Charges dermiques d'acide hyaluronique réticulées avec de l'éther diglycidique de glycol polyéthylénique, leur procédé de fabrication et leurs utilisations
CN113368220A (zh) * 2021-07-05 2021-09-10 云南维他源生物科技有限公司 一种ahco组合物及其制剂与应用
KR20230013682A (ko) 2021-07-16 2023-01-27 주식회사 휴메딕스 Pegde로 가교된 히알루론산 필러 및 이의 제조방법
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin
CN114028610B (zh) * 2021-10-26 2022-10-25 北京诺康达医药科技股份有限公司 一种亲水性注射型皮肤填充组合物及其制备方法与应用
KR102766244B1 (ko) * 2024-02-16 2025-02-10 충남대학교 산학협력단 Lc-ms/ms 기반의 히알루론산, bdde 및 bdde 가교된 히알루론산의 정량방법

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH453269A4 (fr) 1968-03-29 1973-01-31
FR2334107A1 (fr) 1975-12-05 1977-07-01 Pasteur Institut Procede de couplage de substances biologiques par des liaisons covalentes
US4355023A (en) 1980-09-30 1982-10-19 The Massachusetts General Hospital Antibody fragment compositions and process
US4657853A (en) 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
ES2321915T3 (es) 2001-10-25 2009-06-15 University Of Connecticut Composiciones de fibroina y metodos para preparar las mismas.
WO2003045336A1 (fr) 2001-11-29 2003-06-05 National Institute Of Agrobiological Sciences Emulsifiant et procede d'elaboration correspondant
US7632873B2 (en) 2002-12-13 2009-12-15 L'oreal S.A. Cosmetic dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition
EP1592715A1 (fr) 2003-01-31 2005-11-09 Biosphere S.p.A. Gels solubles et biocompatibles d'acide hyalonurique reticule avec des l-acides amines ou des l-aminoesters bifonctionnels
US7060260B2 (en) 2003-02-20 2006-06-13 E.I. Du Pont De Nemours And Company Water-soluble silk proteins in compositions for skin care, hair care or hair coloring
US7115388B2 (en) 2003-03-14 2006-10-03 National Institute Of Agrobiological Sciences Production of functional polypeptides originating from silk protein and use thereof
US8153591B2 (en) 2003-08-26 2012-04-10 Gel-Del Technologies, Inc. Protein biomaterials and biocoacervates and methods of making and using thereof
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
WO2007041677A2 (fr) 2005-10-03 2007-04-12 Combinatorx, Incorporated Implants de tissus mous et compositions de médicaments combinés, et leur utilisation
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
WO2010027471A2 (fr) 2008-09-04 2010-03-11 The General Hospital Corporation Hydrogels pour l'augmentation et la réparation des cordes vocales et de tissu mou
JP5123873B2 (ja) 2009-02-20 2013-01-23 出光テクノファイン株式会社 繊維架橋体および繊維架橋体の製造方法
JP2010213984A (ja) 2009-03-18 2010-09-30 Naisemu:Kk 柔軟剤及び/又は保湿剤含有生体埋込用医療材料、該医療材料中の柔軟剤及び/又は保湿剤の含有量を調整する方法及び、該生体内埋込用医療材料の製造方法
US20110189292A1 (en) * 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
WO2011059325A2 (fr) * 2009-11-11 2011-05-19 University Of Twente, Institute For Biomedical Technology And Technical Medicine (Mira) Hydrogels à base de dextrane et d'acide hyaluronique
AU2015275313A1 (en) 2010-11-08 2016-01-21 Allergan Industrie, Sas Hyaluronic acid based formulations
AU2012262047A1 (en) 2011-06-03 2014-01-16 Allergan, Inc. Dermal filler compositions including antioxidants
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
KR20220013588A (ko) * 2011-09-14 2022-02-04 알러간, 인코포레이티드 잔주름 치료를 위한 진피 필러 조성물
MX2014005704A (es) 2011-11-09 2015-02-17 Tufts College Espumas de fibroina de seda inyectables y sus usos.
US20150079012A1 (en) 2012-04-20 2015-03-19 Trustees Of Tufts College Silk fibroin-based personal care compositions
US20140023688A1 (en) 2012-07-13 2014-01-23 Firmenich Sa Encapsulated oils
CN102836465B (zh) * 2012-08-30 2014-06-04 浙江星月生物科技股份有限公司 一种注射用丝素蛋白透明质酸复合凝胶及其制备与应用
WO2014055895A1 (fr) * 2012-10-05 2014-04-10 Allergan, Inc. Dispositif injectable et méthode de modelage, d'augmentation ou de correction de traits faciaux tels que du menton
EP2903589B1 (fr) 2012-10-08 2018-04-18 Anteis SA Formulation aqueuse stérile injectable à base d'acide hyaluronique réticulé et d'hydroxyapatite pour usage esthétique
WO2014127007A1 (fr) 2013-02-12 2014-08-21 Seryx Biomedical, Inc. Formulation ophtalmique dérivée de protéine de soie
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US20140315828A1 (en) 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
WO2014189780A2 (fr) 2013-05-20 2014-11-27 Tufts University Appareil et procédé de formation d'un composite hydrogel à base de nanofibres
FR3006689A1 (fr) 2013-06-11 2014-12-12 Benedicte Vincente Tauzin Procede de reticulation de l'acide hyaluronique; procede de preparation d'un hydrogel injectable; hydrogel obtenu; utilisation de l'hydroget obtenu
CA2916330A1 (fr) 2013-06-28 2014-12-31 Galderma S.A. Procede pour preparer un produit reticule d'acide hyaluronique
US20160193106A1 (en) 2013-08-20 2016-07-07 Wake Forest University Health Sciences Tissue repair devices utilizing self-assembled materials
JP6775751B2 (ja) 2013-09-30 2020-10-28 エボルブド バイ ネイチャー, インコーポレイテッド 絹タンパク質断片組成物及びそれから製造された物品
JP6369783B2 (ja) 2014-06-12 2018-08-08 株式会社アーダン 加水分解フィブロインを含む軟膏及びその製造方法
PE20171791A1 (es) 2014-12-02 2017-12-28 Silk Therapeutics Inc Prendas de vestir de seda y productos de alto rendimiento y metodos para elaborarla
WO2016115159A1 (fr) 2015-01-12 2016-07-21 Silk Therapeutics, Inc. Compositions de fragment de protéine de soie conservées et articles
US11878070B2 (en) * 2015-04-29 2024-01-23 Evolved By Nature, Inc. Silk-based moisturizer compositions and methods thereof
FR3036035B1 (fr) 2015-05-11 2018-10-05 Laboratoires Vivacy Compositions comprenant au moins un polyol et au moins un anesthesique
KR20180014042A (ko) 2015-05-29 2018-02-07 알바트로스 테크놀로지스 리미티드 약물을 전달하기 위한 가교된 히알루론산 및 이를 이용한 약학적 제제
CN104998302B (zh) 2015-08-31 2017-11-24 中原工学院 一种以取向纳米纤维毡为骨架的纳米软骨修复材料及其制备方法
TWI727014B (zh) 2016-03-24 2021-05-11 德商梅茲製藥有限兩合公司 修飾透明質酸與其製造方法及其用途
US10175996B2 (en) 2016-05-02 2019-01-08 Norman R. Byrne Information display and control for work areas
AU2017315431B2 (en) 2016-08-24 2020-06-25 Allergan, Inc. Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
WO2018081815A2 (fr) 2016-10-31 2018-05-03 Sofregen Medical, Inc. Compositions comprenant des particules de fibroïne de soie et leurs utilisations
CN106492279A (zh) 2016-11-04 2017-03-15 武汉纺织大学 一种丝素蛋白‑透明质酸复合凝胶的快速制备方法
CN107880282B (zh) 2016-12-29 2020-09-29 北京键凯科技股份有限公司 一种注射用多元甘醇环氧衍生物交联的透明质酸钠凝胶及其制备方法
IT201700036930A1 (it) 2017-04-04 2018-10-04 Silk Biomaterials S R L Sistema che comprende idrogel e nanofibre
US20230190997A1 (en) * 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
SG11201913229PA (en) 2017-06-26 2020-01-30 Evolved By Nature Inc Silk-hyaluronic acid based tissue fillers and methods of using the same
CN107619481B (zh) 2017-08-09 2020-08-14 浙江理工大学 一种利用桑蚕丝制备粘性丝素蛋白水凝胶的方法
EP3501553A1 (fr) 2017-12-21 2019-06-26 Association for the Advancement of Tissue Engineering and Cell based Technologies & Therapies (A4TEC) - Associação Hydrogel comprenant du manganèse, ses procédés et utilisations
CN108392680B (zh) 2018-02-09 2020-12-18 珠海睿展生物材料有限公司 一种可塑形全降解硬组织填充生物材料
WO2020132331A1 (fr) 2018-12-19 2020-06-25 Evolved By Nature, Inc. Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés de préparation et d'utilisation

Also Published As

Publication number Publication date
AU2018290810A1 (en) 2020-02-13
CN111263646A (zh) 2020-06-09
EP3645063A4 (fr) 2021-04-14
US12611484B2 (en) 2026-04-28
US20230338614A1 (en) 2023-10-26
CO2020000774A2 (es) 2020-05-05
AU2018290810C1 (en) 2024-09-12
IL299584A (en) 2023-03-01
JP2025020289A (ja) 2025-02-12
KR20200032103A (ko) 2020-03-25
UA127350C2 (uk) 2023-07-26
IL271692B2 (en) 2023-06-01
AU2024219582A1 (en) 2024-10-03
BR112019027687A2 (pt) 2020-09-15
EP4169539B1 (fr) 2025-01-29
EP3645063B1 (fr) 2022-09-28
ES2935887T3 (es) 2023-03-13
IL271692A (en) 2020-02-27
JP2020525253A (ja) 2020-08-27
JP2023139249A (ja) 2023-10-03
AU2018290810B2 (en) 2024-06-13
SG11201913229PA (en) 2020-01-30
JP7660619B2 (ja) 2025-04-11
ES3018883T3 (en) 2025-05-19
WO2019005848A1 (fr) 2019-01-03
EP4169539C0 (fr) 2025-01-29
EP4169539A1 (fr) 2023-04-26
EP3645063A1 (fr) 2020-05-06
CA3068296A1 (fr) 2019-01-03

Similar Documents

Publication Publication Date Title
EP3645063A4 (fr) Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés d'utilisation
EP3493676A4 (fr) Compositions antimicrobiennes à base de polymère et leurs procédés d'utilisation
MA54563A (fr) Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés de préparation et d'utilisation
MA45280A (fr) Conjugués anticorps-médicament à base d'éribuline et leurs procédés d'utilisation
EP3790596A4 (fr) Compositions d'oligonucléotides et leurs procédés d'utilisation
EP3775203A4 (fr) Compositions d'oligonucléotides et leurs procédés d'utilisation
EP3684423A4 (fr) Virus adéno-associé à variant de capsides et leurs procédés d'utilisation
EP3634430A4 (fr) Agents multibiotiques et procédés d'utilisation de ceux-ci
EP3717636A4 (fr) Variants de capsides de virus adéno-associé et leurs procédés d'utilisation
EP3630199A4 (fr) Compositions d'oligonucléotides et leurs procédés d'utilisation
EP3630788A4 (fr) Compositions d'oligonucléotides et leurs procédés d'utilisation
EP3630789A4 (fr) Compositions d'oligonucléotides et leurs procédés d'utilisation
EP3432933A4 (fr) Adhésifs biocompatibles et leurs procédés d'utilisation
EP3704239A4 (fr) Compositions de casz et procédés d'utilisation
EP3684364A4 (fr) Pyridazinones et leurs procédés d'utilisation
EP3416634A4 (fr) Agents immunomodulateurs et leurs procédés d'utilisation
EP3436061A4 (fr) Compositions de conjugués saccharide-polypeptide polymérisables et leurs procédés d'utilisation
EP3436048A4 (fr) Néoantigènes et leurs procédés d'utilisation
MA47499A (fr) Anticorps anti-tau et leurs procédés d'utilisation
EP3377042A4 (fr) Substances et procédés de traitement de myopathies à base de titine et d'autres titinopathies
EP3472200A4 (fr) Anticorps anti-myostatine et leurs procédés d'utilisation
EP3435956A4 (fr) Compositions photo-stabilisées et leurs procédés d'utilisation
EP3731867A4 (fr) Anticorps anti-lrp5/6 et leurs procédés d'utilisation
EP3436476A4 (fr) Anticorps anti-ryk et leurs procédés d'utilisation
EP3635000A4 (fr) Manabodies et procédés d'utilisation