MA50047A - Administration orale d'analogues peptidiques de glp-1 - Google Patents

Administration orale d'analogues peptidiques de glp-1

Info

Publication number: MA50047A
Authority: MA; Morocco
Prior art keywords: glp; oral administration; peptidic analogues; peptidic; analogues
Prior art date: 2017-10-31

Application number

MA050047A

Other languages

English (en)

Inventor

Sergei Pechenov

Janardhanan Anand Subramony

Puneet Tyagi

Original Assignee

Medimmune Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-10-31

Filing date

2018-10-30

Publication date

2020-07-08

2018-10-30 Application filed by Medimmune Ltd filed Critical Medimmune Ltd

2020-07-08 Publication of MA50047A publication Critical patent/MA50047A/fr

Links

102100025101 GATA-type zinc finger protein 1 Human genes 0.000 title 1
101710198884 GATA-type zinc finger protein 1 Proteins 0.000 title 1
DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

MA050047A 2017-10-31 2018-10-30 Administration orale d'analogues peptidiques de glp-1 MA50047A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201762579186P	2017-10-31	2017-10-31

Publications (1)

Publication Number	Publication Date
MA50047A true MA50047A (fr)	2020-07-08

Family

ID=66331379

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA050047A MA50047A (fr)	2017-10-31	2018-10-30	Administration orale d'analogues peptidiques de glp-1

Country Status (23)

Country	Link
US (1)	US11173124B2 (fr)
EP (1)	EP3703817A4 (fr)
JP (1)	JP2021501172A (fr)
KR (1)	KR20200081411A (fr)
CN (1)	CN111655338A (fr)
AR (1)	AR116451A1 (fr)
AU (1)	AU2018360382A1 (fr)
BR (1)	BR112020008220A2 (fr)
CA (1)	CA3079376A1 (fr)
CL (1)	CL2020001131A1 (fr)
CO (1)	CO2020005485A2 (fr)
CR (1)	CR20200185A (fr)
DO (1)	DOP2020000082A (fr)
EA (1)	EA202091095A1 (fr)
IL (1)	IL274096A (fr)
MA (1)	MA50047A (fr)
MX (1)	MX2020004497A (fr)
PE (1)	PE20210116A1 (fr)
PH (1)	PH12020551018A1 (fr)
SG (1)	SG11202003627PA (fr)
TW (1)	TW201932139A (fr)
WO (1)	WO2019087083A2 (fr)
ZA (1)	ZA202003149B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111655338A (zh)	2017-10-31	2020-09-11	免疫医疗有限公司	Glp-1肽类似物的口服递送
WO2022114908A1 (fr) *	2020-11-27	2022-06-02	(주)디앤디파마텍	Formulation orale de conjugué de matériau biologiquement actif comprenant une fraction biotine, une fraction d'acide gras ou une combinaison de celles-ci couplées à celui-ci
FR3120189B1 (fr) *	2021-03-01	2024-11-29	Farid Bennis	Composition pharmaceutique pour une administration par voie orale d’un agoniste du récepteur du GLP-1
KR20230010571A (ko)	2021-07-12	2023-01-19	한미약품 주식회사	Glp-1 유사체를 함유하는 경구 투여 제형 조성물
WO2023065231A1 (fr) *	2021-10-21	2023-04-27	Guangzhou Dazhou Biomedicine Ltd.	Administration orale d'agents thérapeutiques
EP4482472A1 (fr) *	2022-02-22	2025-01-01	Astrazeneca AB	Formulations de caprate de sodium compressible
US12605427B2 (en) *	2023-05-15	2026-04-21	Red Mountain Med Spa, LLC	Sublingual semaglutide-BPC 157 combination for weight loss

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5556837A (en) *	1994-08-01	1996-09-17	Regeneron Pharmaceuticals Inc.	Methods for treating addictive disorders
GB0308734D0 (en) *	2003-04-15	2003-05-21	Axcess Ltd	Uptake of macromolecules
JP5675952B2 (ja) *	2011-02-24	2015-02-25	久光製薬株式会社	マイクロニードルデバイス用ｇｌｐ−１アナログ組成物
HK1208155A1 (en) *	2012-03-28	2016-02-26	Amylin Pharmaceuticals, Llc	Transmucosal delivery of engineered polypeptides
KR102272671B1 (ko) *	2013-05-02	2021-07-06	노보 노르디스크 에이/에스	Glp-1 화합물의 경구 투여
JP2016524617A (ja) *	2013-05-30	2016-08-18	ノヴォノルディスクアー／エス	糖尿病の治療のための新規な経口医薬組成物
TWI726889B (zh) *	2015-06-10	2021-05-11	英商梅迪繆思有限公司	蛋白酶抗性之脂化肽
CN106366166A (zh) *	2016-08-30	2017-02-01	苏州普罗达生物科技有限公司	脑源性神经营养因子促进剂多肽及应用
CN111655338A (zh) *	2017-10-31	2020-09-11	免疫医疗有限公司	Glp-1肽类似物的口服递送

2018
- 2018-10-30 CN CN201880083797.2A patent/CN111655338A/zh active Pending
- 2018-10-30 KR KR1020207014548A patent/KR20200081411A/ko not_active Ceased
- 2018-10-30 SG SG11202003627PA patent/SG11202003627PA/en unknown
- 2018-10-30 US US16/760,250 patent/US11173124B2/en not_active Expired - Fee Related
- 2018-10-30 WO PCT/IB2018/058514 patent/WO2019087083A2/fr not_active Ceased
- 2018-10-30 PE PE2020000457A patent/PE20210116A1/es unknown
- 2018-10-30 EA EA202091095A patent/EA202091095A1/ru unknown
- 2018-10-30 CA CA3079376A patent/CA3079376A1/fr not_active Abandoned
- 2018-10-30 MX MX2020004497A patent/MX2020004497A/es unknown
- 2018-10-30 CR CR20200185A patent/CR20200185A/es unknown
- 2018-10-30 AU AU2018360382A patent/AU2018360382A1/en not_active Abandoned
- 2018-10-30 JP JP2020524064A patent/JP2021501172A/ja active Pending
- 2018-10-30 MA MA050047A patent/MA50047A/fr unknown
- 2018-10-30 BR BR112020008220-1A patent/BR112020008220A2/pt not_active Application Discontinuation
- 2018-10-30 EP EP18874364.5A patent/EP3703817A4/fr not_active Withdrawn
- 2018-10-31 AR ARP180103167A patent/AR116451A1/es unknown
- 2018-10-31 TW TW107138546A patent/TW201932139A/zh unknown
2020
- 2020-04-21 IL IL274096A patent/IL274096A/en unknown
- 2020-04-29 PH PH12020551018A patent/PH12020551018A1/en unknown
- 2020-04-29 CL CL2020001131A patent/CL2020001131A1/es unknown
- 2020-04-30 CO CONC2020/0005485A patent/CO2020005485A2/es unknown
- 2020-05-06 DO DO2020000082A patent/DOP2020000082A/es unknown
- 2020-05-27 ZA ZA2020/03149A patent/ZA202003149B/en unknown

Also Published As

Publication number	Publication date
ZA202003149B (en)	2021-06-30
CL2020001131A1 (es)	2020-10-23
KR20200081411A (ko)	2020-07-07
IL274096A (en)	2020-06-30
EP3703817A4 (fr)	2021-08-18
DOP2020000082A (es)	2020-08-31
AU2018360382A1 (en)	2020-06-18
EA202091095A1 (ru)	2020-09-18
JP2021501172A (ja)	2021-01-14
PH12020551018A1 (en)	2021-05-31
EP3703817A2 (fr)	2020-09-09
PE20210116A1 (es)	2021-01-19
CA3079376A1 (fr)	2019-05-09
US20200323782A1 (en)	2020-10-15
SG11202003627PA (en)	2020-05-28
WO2019087083A2 (fr)	2019-05-09
CR20200185A (es)	2020-06-19
CN111655338A (zh)	2020-09-11
TW201932139A (zh)	2019-08-16
MX2020004497A (es)	2020-08-13
WO2019087083A3 (fr)	2019-08-08
AR116451A1 (es)	2021-05-12
BR112020008220A2 (pt)	2020-10-27
CO2020005485A2 (es)	2020-05-15
US11173124B2 (en)	2021-11-16

Publication	Publication Date	Title
MA50047A (fr)	2020-07-08	Administration orale d'analogues peptidiques de glp-1
IL283134A (en)	2021-06-30	Alcohol-resistant drug formulations
EP3256149A4 (fr)	2019-08-14	Formulations pour administration orale d'agents actifs
MA56006A (fr)	2022-05-04	Formulations sous-cutanées d'anticorps her2
MA46180A (fr)	2021-03-24	Analogues de l'amyline
IL264065A (en)	2019-01-31	Oral gastroretentive formulations and uses thes thereof
EP3407973A4 (fr)	2019-09-11	Analogues de cannabidiol biologiquement actifs
EP3870263A4 (fr)	2022-08-03	Dispositif d'administration
EP3849579A4 (fr)	2022-06-15	Formulations orales d'agonistes des récepteurs opiacés kappa
EP3836866A4 (fr)	2022-06-15	Systèmes d'administration entérique d'agents thérapeutiques
EP3525841C0 (fr)	2026-02-25	Micro-dispositif d'administration
EP3643353A4 (fr)	2021-06-30	Robot d'administration de médicament
IL268905B (en)	2021-12-01	Phage therapy
IL264880A (en)	2019-04-30	Preparations for oral administration of active substances
DK3886820T3 (da)	2023-05-15	Kapselformuleringer
MA52019A (fr)	2021-01-20	Schéma posologique de modulateur d'assemblage de capside
EP3793609C0 (fr)	2023-12-13	Formulation de solution orale
MA54289A (fr)	2021-10-06	Analogues deutérés d'acétyl-leucine
EP3903723A4 (fr)	2022-04-20	Combiné d'implant dentaire
DK3762009T3 (da)	2022-06-20	Toxin-afledte indgivelseskonstrukter til oral indgivelse
EP3723836A4 (fr)	2021-11-24	Dispositif d'administration intranasale
EP3525772A4 (fr)	2020-06-03	Formulations destinées à l'administration entérique d'agents thérapeutiques
HUE061877T2 (hu)	2023-08-28	Ciklosporin-analógok gyógyszerkészítményei
EP3851070A4 (fr)	2022-06-08	Structure d'implant
EP3630074C0 (fr)	2023-10-25	Forme posologique orale multiparticulaire à libération prolongée de tapentadol