MA50086A - Vésicules extracellulaires (ev) bactériennes - Google Patents

Vésicules extracellulaires (ev) bactériennes

Info

Publication number
MA50086A
MA50086A MA050086A MA50086A MA50086A MA 50086 A MA50086 A MA 50086A MA 050086 A MA050086 A MA 050086A MA 50086 A MA50086 A MA 50086A MA 50086 A MA50086 A MA 50086A
Authority
MA
Morocco
Prior art keywords
vesicles
bacterial extracellular
extracellular
bacterial
Prior art date
Application number
MA050086A
Other languages
English (en)
Inventor
Baundauna Bose
Christopher J H Davitt
Brian Goodman
Original Assignee
Evelo Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evelo Biosciences Inc filed Critical Evelo Biosciences Inc
Publication of MA50086A publication Critical patent/MA50086A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • A61K2039/55594Adjuvants of undefined constitution from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
MA050086A 2017-09-08 2018-09-10 Vésicules extracellulaires (ev) bactériennes MA50086A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762556015P 2017-09-08 2017-09-08
US201862669151P 2018-05-09 2018-05-09

Publications (1)

Publication Number Publication Date
MA50086A true MA50086A (fr) 2020-07-15

Family

ID=63832482

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050086A MA50086A (fr) 2017-09-08 2018-09-10 Vésicules extracellulaires (ev) bactériennes

Country Status (14)

Country Link
US (2) US11524037B2 (fr)
EP (1) EP3678693A1 (fr)
JP (1) JP7369690B2 (fr)
KR (1) KR20200053531A (fr)
CN (1) CN111148531A (fr)
AR (1) AR113011A1 (fr)
AU (1) AU2018330322A1 (fr)
BR (1) BR112020004264A2 (fr)
CA (1) CA3075268A1 (fr)
CO (1) CO2020004233A2 (fr)
MA (1) MA50086A (fr)
MX (1) MX2020002659A (fr)
TW (1) TWI814739B (fr)
WO (1) WO2019051380A1 (fr)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11542468B2 (en) * 2016-06-14 2023-01-03 Healthbiome Agathobaculum sp. strain having prophylactic or therapeutic effects on degenerative brain diseases and use thereof
IL308091B1 (en) 2016-09-13 2026-01-01 Allergan Inc Protein-free stabilized Clostridium toxin preparations
CN111148511A (zh) 2017-07-27 2020-05-12 轨迹Ip有限责任公司 用于提高药物、补充剂和摄入物质的生物利用度的组合物
MX2020002659A (es) 2017-09-08 2020-09-09 Evelo Biosciences Inc Vesiculas extracelulares bacterianas.
CN112074283A (zh) * 2018-02-06 2020-12-11 伊夫罗生物科学公司 使用韦荣氏球菌属细菌治疗癌症和免疫病症的组合物和方法
KR102122898B1 (ko) * 2018-02-26 2020-06-15 주식회사 엠디헬스케어 블라우티아 속 세균 유래 나노소포 및 이의 용도
WO2019178490A1 (fr) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions et procédés pour traiter le cancer et l'inflammation utilisant klebsiella oxytoca
WO2019178494A1 (fr) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions et méthodes de traitement du cancer et de l'inflammation à l'aide de tyzzerella nexilis
WO2019178487A2 (fr) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions et méthodes de traitement d'une maladie à l'aide de klebsiella quasipneumoniae subsp. similipneumoniae
CA3093709C (fr) 2018-03-16 2024-03-26 Zoetis Services Llc Vaccins peptidiques contre l'interleukine-31
WO2019232122A1 (fr) * 2018-05-30 2019-12-05 University Of Florida Research Foundation, Inc. Efecteur bactérien mécaniste destiné à empêcher l'apoptose de cellules bêta humaines
CN108949699B (zh) * 2018-08-03 2020-09-04 江南大学 一种分泌美洛昔康单克隆抗体的杂交瘤细胞株及其应用
CA3113448A1 (fr) * 2018-09-27 2020-04-02 Research Development Foundation Methodes et compositions probiotiques destinees au traitement de lesions osseuses
CN109207425A (zh) * 2018-09-29 2019-01-15 中国医科大学附属口腔医院 牙龈卟啉单胞菌诱导巨噬细胞外泌体rna表达研究方法
US20220016189A1 (en) * 2018-12-10 2022-01-20 Md Healthcare Inc. Weissella bacteria-derived nanovesicle and use thereof
JP7291424B2 (ja) * 2019-01-09 2023-06-15 エムディー ヘルスケア インコーポレイテッド デイノコッカス属細菌由来ナノ小胞及びその用途
US20220047648A1 (en) * 2019-01-09 2022-02-17 Md Healthcare Inc. Nanovesicles derived from bacteria of genus rhodococcus, and use thereof
CN109762762A (zh) * 2019-01-11 2019-05-17 江苏大学 一种脂肽的高产菌株及其制备方法和用途
KR102285335B1 (ko) * 2019-02-14 2021-08-04 주식회사 엠디헬스케어 로치아 속 세균 유래 나노소포 및 이의 용도
MX2021010160A (es) * 2019-02-22 2021-09-14 Evelo Biosciences Inc Preparaciones de membrana bacteriana.
CN110195028B (zh) * 2019-03-08 2022-03-01 大连理工大学 一种堆肥低温复合发酵菌剂的制备方法及应用
US11857582B2 (en) * 2019-04-17 2024-01-02 Biogaia Ab Therapeutic microvesicles of probiotic bacteria
US20220218811A1 (en) * 2019-04-17 2022-07-14 Codiak Biosciences, Inc. Methods of treating tuberculosis
CN111991427A (zh) * 2019-05-07 2020-11-27 瑞微(深圳)生物科技有限公司 肠道细菌在制备用于促进TCR γδ+T细胞增殖的药物中的应用
CN110317744B (zh) * 2019-05-08 2021-11-05 安徽农业大学 一种生产蓝紫色素的马赛菌及其生产蓝紫色素的方法
CN114650831A (zh) * 2019-06-11 2022-06-21 伊夫罗生物科学公司 经加工的微生物胞外囊泡
WO2020257382A1 (fr) * 2019-06-20 2020-12-24 Locus Ip Company, Llc Co-culture d'une myxobacterium et d'acinetobacter pour une production améliorée d'émulsan
AU2020316330A1 (en) * 2019-07-19 2022-01-06 Finch Therapeutics Holdings Llc. Methods and products for treatment of gastrointestinal disorders
WO2021026130A1 (fr) * 2019-08-05 2021-02-11 Evelo Biosciences, Inc. Compositions et procédés de traitement du psoriasis et de la dermatite atopique faisant appel à prevotella histicola
CN110577910B (zh) * 2019-09-17 2022-02-01 南京农业大学 一种侧孢短芽孢杆菌、抗菌脂肽及其在农业与食品上的应用
EP4031152A4 (fr) * 2019-09-18 2023-10-04 Research Development Foundation Composés et compositions probiotiques pour le traitement de maladies et de troubles métaboliques
CN110628862A (zh) * 2019-09-24 2019-12-31 哈尔滨工业大学 一种废水梯级能源回收的自聚集颗粒污泥构建方法
CN110982729A (zh) * 2019-10-23 2020-04-10 江苏省中国科学院植物研究所 一种降解木材加工副产物杨树皮纤维素的复合菌剂
CN110804621A (zh) * 2019-10-31 2020-02-18 郑州大学 一种内源性高表达miRNA的大肠杆菌胞外囊泡的制备方法
US20230081756A1 (en) * 2019-12-31 2023-03-16 Xbiome Inc. Compositions comprising bacterial species and methods related thereto
WO2021137494A1 (fr) * 2020-01-02 2021-07-08 삼육대학교산학협력단 Composition pour la prévention ou le traitement du diabète comprenant une souche de butyricimonas sp. en tant que principe actif
TW202140050A (zh) * 2020-01-10 2021-11-01 美商艾弗洛生物科技股份有限公司 使用小韋榮氏球菌進行治療的組成物及方法
EP4090321A1 (fr) * 2020-01-13 2022-11-23 Vaximm AG Vaccins à adn à base de salmonella en combinaison avec un antibiotique
TW202140051A (zh) * 2020-01-17 2021-11-01 美商艾弗洛生物科技股份有限公司 具有改善的崩散譜之固體劑型
US20240009256A1 (en) * 2020-02-04 2024-01-11 University Of Louisville Research Foundation, Inc. Use of probiotic bacterium-derived extracellular micro- and/or nanoparticles for the treatment of disease
CN111052997B (zh) * 2020-02-25 2022-07-01 青岛农业大学 一种提高草莓连作障碍抗性生物刺激素的制备及应用方法
US11253534B2 (en) 2020-03-23 2022-02-22 Sabine Hazan Method of preventing COVID-19 infection
US11744866B2 (en) 2020-03-18 2023-09-05 Sabine Hazan Methods of preventing and treating COVID-19 infection with probiotics
US11278520B2 (en) 2020-03-31 2022-03-22 Sabine Hazan Method of preventing COVID-19 infection
US20230158088A1 (en) * 2020-03-26 2023-05-25 Persephone Biosciences, Inc. Compositions for modulating gut microflora populations, enhancing drug potency and treating viral infections, and methods for making and using same
WO2021203083A2 (fr) * 2020-04-02 2021-10-07 Dupont Nutrition Biosciences Aps Compositions pour la santé métabolique
WO2021205444A1 (fr) * 2020-04-06 2021-10-14 Yeda Research And Development Co. Ltd. Méthodes de diagnostic du cancer et de prédiction de la réactivité à une thérapie
KR102273232B1 (ko) * 2020-05-08 2021-07-06 코스맥스 주식회사 마이크로코커스 리래 균주 및 그의 피부 상태 개선 용도
KR102273234B1 (ko) * 2020-05-08 2021-07-06 코스맥스 주식회사 코쿠리아 바리안스 균주 및 그의 피부 상태 개선 용도
CN111560330B (zh) * 2020-05-12 2022-04-26 天津科技大学 一种具有免疫调节、抗炎和抗宫颈癌作用的干酪乳杆菌及应用
GB202007452D0 (en) 2020-05-19 2020-07-01 Microbiotica Ltd Threrapeutic bacterial composition
WO2021242056A1 (fr) * 2020-05-28 2021-12-02 주식회사 바이오뱅크힐링 Souche de l'espèce bifidobacterium et vésicule extracellulaire dérivée de cette dernière, et leurs utilisations anti-inflammatoires et antibactériennes
WO2021252861A1 (fr) * 2020-06-11 2021-12-16 Evelo Biosciences, Inc. Compositions et méthodes de traitement de maladies et de troubles à l'aide de mégasphaera sp.
KR20230038476A (ko) * 2020-06-11 2023-03-20 에벨로 바이오사이언시즈, 인크. 오실로스피라세애 미생물 세포외 소포를 사용하여 질환 및 장애를 치료하기 위한 조성물 및 방법
WO2021252860A2 (fr) * 2020-06-11 2021-12-16 Evelo Biosciences, Inc. Compositions et méthodes de traitement de maladies et de troubles à l'aide d'harryflintia acetispora
WO2021252838A1 (fr) * 2020-06-11 2021-12-16 Evelo Biosciences, Inc. Compositions et méthodes de traitement de maladies et de troubles à l'aide de fournierella massiliensis
JP7385301B2 (ja) * 2020-06-16 2023-11-22 エムディー ヘルスケア インコーポレイテッド ラクトバチルス・パラカゼイ由来小胞を含む神経疾患又は精神疾患の予防又は治療用組成物
CN116056723A (zh) * 2020-06-22 2023-05-02 罗塞塔外排体株式会社 增强细菌胞外囊泡的癌症治疗效果的方法和组合物
KR102469138B1 (ko) * 2020-07-07 2022-11-22 주식회사 엘제이바이오 파라클로스트리디움 벤조에리티쿰 ks3 균주를 포함하는 가축 사체 분해 촉진용 미생물 제제
CN111743922B (zh) * 2020-07-14 2022-03-29 华熙生物科技股份有限公司 一种提高益生菌在鼻腔中的定植和活性的组合物及在鼻腔护理中的应用
KR20230053609A (ko) * 2020-07-21 2023-04-21 에벨로 바이오사이언시즈, 인크. 신경염증성 질환에 대한 경구 요법으로서의 베일로넬라 파르불라 균주
EP4188399A2 (fr) * 2020-08-03 2023-06-07 Universiteit Gent Compositions bactériennes présentant une activité anti-inflammatoire
CN111876359A (zh) * 2020-08-04 2020-11-03 榆林沙漠王生物科技有限公司 一种用于蔬菜残体资源化处理的复配菌剂及其制备方法及应用
KR20220021878A (ko) * 2020-08-14 2022-02-22 주식회사 고바이오랩 피칼리박테리움 프라우스니치이 균주 및 그 용도
CN112094820B (zh) * 2020-09-17 2021-12-07 扬州大学 霍氏肠杆菌噬菌体yzu.p.a-5及其应用
JP2023543416A (ja) * 2020-09-18 2023-10-16 エヴェロ バイオサイエンシズ,インコーポレーテッド 細菌の固形剤形
WO2022061123A1 (fr) * 2020-09-21 2022-03-24 Evelo Biosciences, Inc. Formes posologiques solides à profils de désintégration améliorés
CN112094328A (zh) * 2020-09-21 2020-12-18 华南农业大学 一种空肠弯曲杆菌外膜囊泡的提取及纯化方法
CN112094778B (zh) * 2020-09-24 2022-06-24 千禾味业食品股份有限公司 一种魏斯氏菌las1、制备方法及其应用
TW202233213A (zh) * 2020-10-29 2022-09-01 美商艾弗洛生物科技股份有限公司 包含螺旋藻組分之組成物
CN114438235A (zh) * 2020-11-04 2022-05-06 深圳市南山区疾病预防控制中心 一种同时检测嗜低温弓形杆菌及斯氏弓形杆菌的引物探针组件、试剂盒及其应用
US20240033303A1 (en) * 2020-12-08 2024-02-01 Md Healthcare Inc. Composition for preventing or treating neurological diseases or psychiatric diseases comprising vesicles derived from sphingomonas bacteria
KR102269962B1 (ko) 2020-12-11 2021-06-28 주식회사 바이오뱅크힐링 유박테리움 리모숨 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
FR3118060B1 (fr) * 2020-12-18 2025-03-14 Univ Bourgogne Utilisation anti-biofilm de vesicules membranaires extracellulaires
WO2022139530A1 (fr) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 Composition destinée à réduire, prévenir ou traiter des maladies auto-immunes comprenant des vésicules extracellulaires dérivées de lactobacillus sakei en tant que principe actif
WO2022139531A1 (fr) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 Composition pour améliorer, prévenir ou traiter une stéatose hépatique comprenant des vésicules extracellulaires dérivées de leuconostoc citreum en tant que principe actif
WO2022139532A1 (fr) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 Composition pour améliorer, prévenir ou traiter une stéatose hépatique, comprenant une vésicule extracellulaire dérivée de weissella hellenica en tant que principe actif
WO2022145900A1 (fr) * 2020-12-28 2022-07-07 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique pour la prévention ou le traitement du cancer, comprenant en tant que principe actif des nanovésicules issues d'une souche de weissella cibaria
EP4268835A4 (fr) * 2020-12-28 2024-11-27 MD Healthcare Inc. Composition pour la prévention ou le traitement d'une maladie pulmonaire neutrophile comprenant des vésicules extracellulaires dérivées de micrococcus luteus
EP4268836A4 (fr) * 2020-12-28 2024-11-27 MD Healthcare Inc. Composition pour la prévention ou le traitement de maladies neuro-développementales, neurologiques ou psychiatriques, comprenant des vésicules extracellulaires dérivées de micrococcus luteus
KR102651196B1 (ko) * 2020-12-28 2024-03-27 주식회사 엠디헬스케어 마이크로코커스 루테우스 유래 세포외 소포를 포함하는 안질환 예방 또는 치료용 조성물
WO2022145902A1 (fr) * 2020-12-28 2022-07-07 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique destinée à la prévention ou au traitement du cancer, comprenant des nanovésicules dérivées d'une souche de lactobacillus sakei en tant qu'ingrédient actif
WO2022145901A1 (fr) * 2020-12-28 2022-07-07 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique pour la prévention ou le traitement du cancer comprenant des nanovésicules dérivées d'une souche de lactobacillus fermentum en tant que principe actif
WO2022154149A1 (fr) * 2021-01-14 2022-07-21 (주)엑솔런스 Composition vaccinale utilisant une vésicule extracellulaire
WO2022164012A1 (fr) * 2021-02-01 2022-08-04 주식회사 엠디헬스케어 Composition comprenant des vésicules dérivées de lactobacillus paracasei pour prévenir, traiter ou soulager des maladies infectieuses virales ou des maladies respiratoires
WO2022177412A1 (fr) * 2021-02-22 2022-08-25 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique pour la prévention ou le traitement du cancer comprenant en tant que principe actif des nanovésicules issues d'une souche de weissella cibaria
EP4297762A1 (fr) * 2021-02-26 2024-01-03 Evelo Biosciences, Inc. Compositions et procédés pour réduire l'expression de cytokine
JPWO2022191183A1 (fr) * 2021-03-08 2022-09-15
BR112023018354A8 (pt) * 2021-03-12 2024-03-12 Marvelbiome Inc Métodos e usos de composições, componentes ou metabólitos de microbioma para tratar distúrbios oculares
US20240180833A1 (en) * 2021-04-02 2024-06-06 Md Healthcare Inc. Nanovesicles derived from bacteria of the genus paracoccus and use thereof
CN113186172A (zh) * 2021-04-06 2021-07-30 天津农学院 共表达Apoptin与MEL基因的重组腺病毒及构建方法和应用
WO2022221183A1 (fr) * 2021-04-12 2022-10-20 Evelo Biosciences, Inc. Préparations de vésicules extracellulaires de fournierella
CN113025534B (zh) * 2021-04-26 2022-05-27 佛山市南海东方澳龙制药有限公司 一株具有较强抑菌作用的新种芽孢杆菌x901株及其应用
CN115305211A (zh) * 2021-05-07 2022-11-08 葡萄王生技股份有限公司 益生菌胞外泌体及其用途
CN113186134B (zh) * 2021-05-17 2022-11-01 中国科学院水生生物研究所 一种蓝藻气囊提取方法及其应用
CN113122483A (zh) * 2021-05-31 2021-07-16 哈尔滨工业大学 一种玉米秸秆好氧堆肥的快速产热菌剂及其应用
JP2024520696A (ja) * 2021-06-03 2024-05-24 エムディー ヘルスケア インコーポレイテッド ラクトバチルス菌由来細胞外小胞及びその用途
KR102661178B1 (ko) * 2021-06-03 2024-04-29 주식회사 엠디헬스케어 락토바실러스 파라카세이 유래 세포외소포를 포함하는 안질환 예방 또는 치료용 조성물
WO2022255784A1 (fr) * 2021-06-03 2022-12-08 주식회사 엠디헬스케어 Vésicule dérivée de lactobacillus rhamnosus et ses utilisations
JP7396737B2 (ja) * 2021-06-03 2023-12-12 エムディー ヘルスケア インコーポレイテッド ラクトバチルス・パラカゼイ由来細胞外小胞を含む眼疾患の予防または治療用組成物
US20240261345A1 (en) * 2021-06-07 2024-08-08 Md Healthcare Inc. Composition for preventing or treating inflammatory diseases or cancer, comprising leuconostoc bacteria-derived vesicles
KR102850200B1 (ko) * 2021-06-18 2025-08-27 경북대학교 산학협력단 핵산 백신 제조 및 유전자 전달을 위한 세균 유래 세포밖 소포체의 용도
WO2023287726A1 (fr) 2021-07-12 2023-01-19 Penland Foundation Traitement du cancer à l'aide de toxine botulique et d'oxyde nitreux
CN114128891A (zh) * 2021-07-28 2022-03-04 黑龙江飞鹤乳业有限公司 一种促进婴儿肠道发育的菌株及其应用
WO2023010074A1 (fr) * 2021-07-28 2023-02-02 The Texas A&M University System Compositions de vaccin comprenant des souches de brucella et leurs procédés
KR102390775B1 (ko) * 2021-09-06 2022-05-04 한국식품연구원 류코노스톡 슈도메센테로이데스 WiKim0138 균주를 유효성분으로 포함하는 암의 예방 또는 치료용 조성물
KR102390755B1 (ko) * 2021-09-06 2022-04-28 한국식품연구원 웨이셀라 파라메센테로이데스 WiKim0137 균주를 유효성분으로 포함하는 암의 예방 또는 치료용 조성물
KR102558084B1 (ko) * 2021-09-14 2023-07-21 코스맥스 주식회사 두피 마이크로바이옴 콤플렉스 및 그의 모발 또는 두피 상태 개선 용도
CN113999789B (zh) * 2021-09-30 2022-11-15 沈阳农业大学 一株产鲜味肽的嗜盐四联球菌及应用
AU2021468875A1 (en) * 2021-10-11 2024-05-30 Vastu Vihar Biotech Private Limited An anti-inflammatory composition and a method of obtaining the same
KR102411241B1 (ko) * 2021-10-18 2022-06-22 큐티스바이오 주식회사 코리네박테리움 상귀니스의 피부 상태 개선 용도
KR102411242B1 (ko) * 2021-10-18 2022-06-22 큐티스바이오 주식회사 클렙시엘라 아에로제네스의 피부 상태 개선 용도
KR102881730B1 (ko) * 2021-10-20 2025-11-06 주식회사 고바이오랩 항암 활성을 갖는 신규 박테리아 균주 및 이를 이용한 암의 완화, 예방 또는 치료용 조성물
KR102739746B1 (ko) * 2021-10-25 2024-12-10 인하대학교 산학협력단 바르토넬라 헨셀라이 유래 세포외 소포체를 이용한 바르토넬라 감염증 진단 방법
WO2023075458A1 (fr) * 2021-10-27 2023-05-04 주식회사 바이오뱅크힐링 Nouvelle souche bactérienne, vésicules dérivées de celle-ci, et utilisation anti-inflammatoire et anti-bactérienne associées
CN114085792B (zh) * 2021-11-17 2023-03-24 哈尔滨医科大学 一种用于防治结肠癌的副干酪乳杆菌及其应用
WO2023092141A2 (fr) * 2021-11-22 2023-05-25 Dupont Nutrition Biosciences Aps Compositions pour santé métabolique
CN118488834A (zh) 2021-11-23 2024-08-13 赛欧生物医药股份有限公司 细菌源性脂质组合物和其用途
WO2023114300A1 (fr) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Préparations de vésicules extracellulaires de bactéries fournierella massiliensis
WO2023114293A1 (fr) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Dosages de vésicules extracellulaires
CA3242398A1 (fr) * 2021-12-15 2023-06-22 Board Of Regents, The University Of Texas System Procedes et compositions pour modifier un microbiome tumoral
CN114369673B (zh) * 2022-01-06 2023-07-14 同济大学 结直肠腺瘤生物标志物、试剂盒及生物标志物的筛选方法
JP2025503054A (ja) * 2022-01-20 2025-01-30 コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー ロセブリア属またはビフィドバクテリウム属由来細胞外小胞を含む、非アルコール性脂肪性肝疾患の予防、改善、または治療用組成物
CN114807032B (zh) * 2022-05-20 2023-09-12 南京大学 地塞米松诱导中性粒细胞产生的细胞外囊泡在制备治疗消炎药物中的应用
KR102509869B1 (ko) * 2022-07-14 2023-03-14 주식회사 엔테로바이옴 아커만시아를 포함하는 탈모 예방 또는 치료용 약학적 조성물
KR102626400B1 (ko) * 2022-08-31 2024-01-19 주식회사 바이오뱅크힐링 도레아 론기카테나 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102620189B1 (ko) * 2022-08-31 2024-01-04 주식회사 바이오뱅크힐링 블라우티아 브룩킹시 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102620190B1 (ko) * 2022-08-31 2024-01-04 주식회사 바이오뱅크힐링 아가토박터 렉탈리스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2024049207A1 (fr) * 2022-08-31 2024-03-07 주식회사 바이오뱅크힐링 Nouvelle souche et vésicules qui en sont issues, et leurs utilisations anti-inflammatoires et antibactériennes
CN115590890B (zh) * 2022-10-19 2026-02-17 中南大学湘雅医院 一种双歧杆菌及其胞外囊泡在制备对抗高脂饮食导致的疾病的制剂中的应用
CN116004440B (zh) * 2022-10-25 2025-06-13 深圳未知君生物科技有限公司 一株粘膜粘液乳杆菌及其在制备治疗癌症的药物中的应用
CN115820840A (zh) * 2022-11-23 2023-03-21 武汉轻工大学 一种副猪嗜血杆菌感染后引起仔猪免疫抑制的分子标记物
CN116509900B (zh) * 2022-12-01 2023-11-10 佛山科学技术学院 益生菌或其细胞外囊泡在制备防治胃溃疡产品中的应用
KR20240114298A (ko) * 2023-01-12 2024-07-23 에스엔제이 파마 인크 감염 저항성 장내 균주 및 그 용도
CN116656583B (zh) * 2023-01-13 2024-06-18 南昌大学 靶向肿瘤的幽门螺杆菌突变株及抗胃癌外膜囊泡组合物
CN118496306A (zh) * 2023-02-14 2024-08-16 南京农业大学 一种利用重组枯草芽孢杆菌制备抗应激肽lgspdvivir的方法及应用
KR20240130175A (ko) * 2023-02-21 2024-08-29 주식회사 엠디헬스케어 류코노스톡 속 세균 유래 소포를 포함하는 대사질환, 간질환, 또는 근육질환 예방 또는 치료용 조성물
CN116622548B (zh) * 2023-03-31 2024-02-09 吉林农业大学 一株能够预防和或治疗牙周炎的嵴链球菌及其应用
CN116606766B (zh) * 2023-04-26 2025-02-25 南京农业大学 一种食淀粉乳杆菌胞外囊泡的制备方法及其应用
CN116355811B (zh) * 2023-04-26 2025-03-18 南京农业大学 一种食淀粉乳杆菌及其在改善胆汁淤积性肝病中的应用
CN116747245B (zh) * 2023-06-14 2024-06-21 辽宁越秀辉山营养科技有限公司 动物双歧杆菌乳亚种bx-245在抑菌和/或生产功能活性物质中的应用
CN117180317B (zh) * 2023-11-02 2024-01-26 深圳市第二人民医院(深圳市转化医学研究院) 詹氏乳杆菌来源纳米囊泡在制备防治卵巢早衰治疗药物中的应用
CN117402794B (zh) * 2023-12-12 2024-02-27 四川厌氧生物科技有限责任公司 一种加氏乳杆菌及其应用
KR20250104680A (ko) * 2023-12-29 2025-07-08 한국생명공학연구원 잔티노박테리움 속 균주 또는 비올라세인을 포함하는 발모 촉진 또는 탈모 예방 또는 치료용 조성물
WO2025183435A1 (fr) * 2024-02-26 2025-09-04 주식회사 건강약품 Microvésicules dérivées d'infantis, sous-espèce de bifidobacterium longum, et leurs utilisations
WO2025198344A1 (fr) * 2024-03-20 2025-09-25 이화여자대학교 산학협력단 Nouvelles bactéries lactiques et leur utilisation
CN118006515B (zh) * 2024-04-08 2024-06-18 中国农业大学 一株乳酸乳球菌及其在制备治疗牛乳腺炎的药物中的应用
WO2026021930A2 (fr) 2024-07-24 2026-01-29 Henriques Normark Birgitta Immunisation contre le streptocoque du groupe a (gas)
CN118845855A (zh) * 2024-08-19 2024-10-29 广州医科大学附属第二医院 詹氏乳杆菌来源纳米囊泡在制备预防和/或治疗鼻息肉药物中的应用
CN119530061B (zh) * 2024-11-14 2025-07-25 广东医科大学附属医院 一种肠道微生物组合在制备治疗sle药物中的应用
CN119144523A (zh) * 2024-11-19 2024-12-17 哈尔滨医科大学 一株铅黄肠球菌及其外泌体的应用
CN119752719B (zh) * 2024-12-30 2025-12-16 中国疾病预防控制中心传染病预防控制所 一种纤细副梭菌Pt517及其在制备抗炎或抑菌产品中的应用
CN119932075A (zh) * 2025-01-25 2025-05-06 四川大学 一种携带外源蛋白的重组单增李斯特菌膜囊泡及其制备方法和应用
CN119955687B (zh) * 2025-04-10 2025-07-01 西南民族大学 一株具有益生活性的融合魏斯氏菌dy12及其应用
CN120442727A (zh) * 2025-05-07 2025-08-08 湖南湘农动物药业有限公司 富含有机铜的罗伊氏乳杆菌hadig-lr003后生元的制备及其应用
CN120866469A (zh) * 2025-09-29 2025-10-31 上海交通大学医学院附属仁济医院 一种肠道细菌新生外囊泡的分离检测方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2848965A1 (de) 1978-11-11 1980-05-22 Behringwerke Ag Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
US5322784A (en) 1991-06-05 1994-06-21 The Board Of Trustees Of The University Of Illinois, Urbana-Champaign, Illinois Method and materials for introducing DNA into Prevotella ruminicola
BR0108828A (pt) 2000-03-01 2002-12-10 Nestle Sa Formulação de carboidrato (adjuvante pré-biótico) para aperfeiçoamento de resposta imuno
US6812023B1 (en) 2000-04-27 2004-11-02 Anosys, Inc. Methods of producing membrane vesicles
JP5511117B2 (ja) * 2000-07-27 2014-06-04 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド 髄膜炎菌に起因する疾患に対する広域防御のためのワクチン
GB0130123D0 (en) 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
US20060228351A1 (en) 2003-03-31 2006-10-12 Junichi Masuyama Method of inducing differentiation and proliferating regulatory t cell by anti-cd52 antibody and medicinal composition therefor
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
US20050100559A1 (en) 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
JP5173194B2 (ja) 2003-12-23 2013-03-27 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
US9051565B2 (en) 2007-05-22 2015-06-09 Cornell Research Foundation, Inc. Compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof
WO2011027956A2 (fr) 2009-09-04 2011-03-10 주식회사이언메딕스 Vésicules extracellulaires issues de bactéries à gram positif, et modèle de maladie utilisant celles-ci
JP5818793B2 (ja) 2009-09-01 2015-11-18 イオン メディックス インコーポレイテッド 腸内共生細菌由来細胞外ベシクル、並びにこれを用いた疾病モデル、ワクチン、候補薬物探索方法及び診断方法
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
JP5860402B2 (ja) 2009-10-08 2016-02-16 イオン メディックス インコーポレイテッド 室内空気由来細胞外ベシクルを含む組成物及びその用途
WO2011053653A2 (fr) 2009-10-30 2011-05-05 Mayo Foundation For Medical Education And Research Préparations à base de prevotella histicola et traitement d'états auto-immuns
KR101629525B1 (ko) 2010-01-11 2016-06-13 이화여자대학교 산학협력단 발효식품에서 유래된 세포밖 소포체를 포함하는 조성물 및 이의 용도
AU2011232421B2 (en) 2010-03-23 2015-08-13 Novartis Ag Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc.
EP2589391B1 (fr) 2010-07-01 2018-11-14 Rosetta Exosome Co., Ltd. Microvésicules de cellules bactériennes pour application dans le traitement du cancer
WO2012093755A1 (fr) 2011-01-04 2012-07-12 포항공과대학교 산학협력단 Composition comprenant des vésicules extracellulaires provenant d'une nourriture fermentée et utilisation de celle-ci
WO2012093754A1 (fr) 2011-01-04 2012-07-12 포항공과대학교 산학협력단 Composition comprenant des vésicules extracellulaires provenant de l'intérieur d'un corps de mammifère et utilisation de celle-ci
WO2014152484A1 (fr) 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Microbiote fécal lyophilisé à utiliser dans la transplantation microbienne fécale
CA2829385C (fr) * 2011-03-09 2021-07-13 Michael J. Sadowsky Compositions et procedes de transplantation du microbiote du colon
KR101421779B1 (ko) 2011-04-08 2014-07-28 주식회사이언메딕스 아시네토박터 속 세균유래 세포밖 소포체 및 이의 용도
TWI573590B (zh) 2011-09-20 2017-03-11 雷希爾生藥有限公司 治療自體免疫疾病之組成物及方法
DK2797942T3 (en) 2011-12-28 2018-12-10 Galectin Therapeutics Inc Composition of Hitherto-Unknown Carbohydrate Drugs for the Treatment of Human Diseases
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
AU2014212004B2 (en) 2013-02-04 2018-09-20 Société des Produits Nestlé S.A. Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases
EP2953620A1 (fr) 2013-02-07 2015-12-16 GlaxoSmithKline Biologicals SA Compositions pharmaceutiques contenant des vésicules
PL3016527T3 (pl) 2013-06-03 2019-02-28 Proprev Ab Leczenie otyłości, zespołu metabolicznego, cukrzycy typu 2, chorób sercowo-naczyniowych, otępienia, choroby alzheimera i zapalnej choroby jelit poprzez zastosowanie co najmniej jednego szczepu bakteryjnego prevotella
KR101740893B1 (ko) 2014-05-20 2017-06-13 주식회사 엠디헬스케어 Akkermansia muciniphila 균에서 유래하는 세포밖 소포를 유효성분으로 함유하는 대사질환의 치료 또는 예방용 조성물
AU2015326407C1 (en) 2014-10-03 2021-06-24 Engeneic Molecular Delivery Pty Ltd Enhanced loading of intact, bacterially derived vesicles with small molecule compounds
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
US20170360842A1 (en) 2014-12-03 2017-12-21 Capricor, Inc. Processes for producing stable exosome formulations
KR101726488B1 (ko) 2015-02-23 2017-04-13 이화여자대학교 산학협력단 바실러스 속 세균 유래 세포밖 소포체를 포함하는 임신관련 질환 치료용 조성물
KR20160107632A (ko) 2015-03-04 2016-09-19 포항공과대학교 산학협력단 뉴클레아제가 처리된 세균 유래 세포밖 소포체를 이용한 세균 동정 방법
WO2016144139A2 (fr) 2015-03-11 2016-09-15 주식회사 엠디헬스케어 Composition pour prévenir ou traiter des maladies inflammatoires, comprenant des vésicules extracellulaires dérivées de bactéries d'acide lactique comme principes actifs
AU2016228888A1 (en) 2015-03-12 2017-10-26 The University Of British Columbia Bacterial compositions and methods of use thereof
KR102394638B1 (ko) 2015-09-30 2022-05-09 (주)아모레퍼시픽 유산균 유래의 세포외 소낭을 포함하는 탈모 방지 또는 육모 촉진용 조성물
US20170145061A1 (en) 2015-11-20 2017-05-25 Massachusetts Institute Of Technology Engineered bacteroides outer membrane vesicles
WO2017123025A1 (fr) 2016-01-15 2017-07-20 주식회사 엠디헬스케어 Régulateur pour troubles de la fonction immunitaire des voies respiratoires, utilisant des vésicules extracellulaires d'origine bactérienne
US10722543B2 (en) 2016-01-28 2020-07-28 Oxyrase, Inc. Methods for inhibiting tumor growth using anaerobe microorganisms
JP6441536B2 (ja) 2016-03-04 2018-12-19 フォーディー ファーマ ピーエルシー4D Pharma Plc 細菌株を含む組成物
WO2019051381A1 (fr) 2017-09-08 2019-03-14 Evelo Biosciences, Inc. Vésicules extracellulaires provenant de prevotella
MX2020002659A (es) 2017-09-08 2020-09-09 Evelo Biosciences Inc Vesiculas extracelulares bacterianas.

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US20200254028A1 (en) 2020-08-13
CA3075268A1 (fr) 2019-03-14
KR20200053531A (ko) 2020-05-18
US11524037B2 (en) 2022-12-13
AU2018330322A1 (en) 2020-03-19
CO2020004233A2 (es) 2020-04-24
TW201919673A (zh) 2019-06-01
EP3678693A1 (fr) 2020-07-15
MX2020002659A (es) 2020-09-09
TWI814739B (zh) 2023-09-11
AR113011A1 (es) 2020-01-15
JP2020533290A (ja) 2020-11-19
US20230210913A1 (en) 2023-07-06
BR112020004264A2 (pt) 2020-10-06
US12109243B2 (en) 2024-10-08
CN111148531A (zh) 2020-05-12
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