MA50086A - Vésicules extracellulaires (ev) bactériennes - Google Patents

Vésicules extracellulaires (ev) bactériennes

Info

Publication number
MA50086A
MA50086A MA050086A MA50086A MA50086A MA 50086 A MA50086 A MA 50086A MA 050086 A MA050086 A MA 050086A MA 50086 A MA50086 A MA 50086A MA 50086 A MA50086 A MA 50086A
Authority
MA
Morocco
Prior art keywords
vesicles
bacterial extracellular
extracellular
bacterial
Prior art date
Application number
MA050086A
Other languages
English (en)
Inventor
Baundauna Bose
Christopher J H Davitt
Brian Goodman
Original Assignee
Evelo Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evelo Biosciences Inc filed Critical Evelo Biosciences Inc
Publication of MA50086A publication Critical patent/MA50086A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
MA050086A 2017-09-08 2018-09-10 Vésicules extracellulaires (ev) bactériennes MA50086A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762556015P 2017-09-08 2017-09-08
US201862669151P 2018-05-09 2018-05-09

Publications (1)

Publication Number Publication Date
MA50086A true MA50086A (fr) 2020-07-15

Family

ID=63832482

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050086A MA50086A (fr) 2017-09-08 2018-09-10 Vésicules extracellulaires (ev) bactériennes

Country Status (14)

Country Link
US (2) US11524037B2 (fr)
EP (1) EP3678693A1 (fr)
JP (1) JP7369690B2 (fr)
KR (1) KR20200053531A (fr)
CN (1) CN111148531A (fr)
AR (1) AR113011A1 (fr)
AU (1) AU2018330322A1 (fr)
BR (1) BR112020004264A2 (fr)
CA (1) CA3075268A1 (fr)
CO (1) CO2020004233A2 (fr)
MA (1) MA50086A (fr)
MX (1) MX2020002659A (fr)
TW (1) TWI814739B (fr)
WO (1) WO2019051380A1 (fr)

Families Citing this family (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017217753A1 (fr) * 2016-06-14 2017-12-21 한국생명공학연구원 Souche du genre agabaculum ayant des effets de prévention ou de traitement des maladies dégénératives du cerveau, et son utilisation
IL265109B2 (en) 2016-09-13 2024-05-01 Allergan Inc Stabilized non-protein clostridial toxin compositions
KR20200024940A (ko) 2017-07-27 2020-03-09 로커스 아이피 컴퍼니 엘엘씨 의약품, 보충제 및 섭취된 물질의 생체 이용률을 향상시키기 위한 조성물
CN111148531A (zh) 2017-09-08 2020-05-12 伊夫罗生物科学公司 细菌胞外囊泡
KR20200118100A (ko) * 2018-02-06 2020-10-14 에벨로 바이오사이언시즈, 인크. 베일로넬라 박테리아를 이용한 암 및 면역 장애를 치료하기 위한 조성물 및 방법
KR102122898B1 (ko) * 2018-02-26 2020-06-15 주식회사 엠디헬스케어 블라우티아 속 세균 유래 나노소포 및 이의 용도
WO2019178487A2 (fr) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions et méthodes de traitement d'une maladie à l'aide de klebsiella quasipneumoniae subsp. similipneumoniae
WO2019178494A1 (fr) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions et méthodes de traitement du cancer et de l'inflammation à l'aide de tyzzerella nexilis
WO2019178490A1 (fr) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions et procédés pour traiter le cancer et l'inflammation utilisant klebsiella oxytoca
WO2019178601A1 (fr) 2018-03-16 2019-09-19 Zoetis Services Llc Vaccins peptidiques contre l'interleukine-31
US12194066B2 (en) 2018-05-30 2025-01-14 University Of Florida Researchfoundation, Incorporated Mechanistic bacterial efector to prevent apoptosis of human beta cells
CN108949699B (zh) * 2018-08-03 2020-09-04 江南大学 一种分泌美洛昔康单克隆抗体的杂交瘤细胞株及其应用
AU2019351019B2 (en) * 2018-09-27 2024-09-19 Research Development Foundation Methods and probiotic compositions for the treatment of bone disorders
CN109207425A (zh) * 2018-09-29 2019-01-15 中国医科大学附属口腔医院 牙龈卟啉单胞菌诱导巨噬细胞外泌体rna表达研究方法
JP7240031B2 (ja) * 2018-12-10 2023-03-15 エムディー ヘルスケア インコーポレイテッド ワイセラ属細菌由来のナノ小胞およびその用途
JP7441534B2 (ja) * 2019-01-09 2024-03-01 エムディー ヘルスケア インコーポレイテッド ロドコッカス属細菌由来ナノ小胞およびその用途
US20220090171A1 (en) * 2019-01-09 2022-03-24 Md Healthcare Inc. Nanovesicles derived from bacteria of genus deinococcus, and use thereof
CN109762762A (zh) * 2019-01-11 2019-05-17 江苏大学 一种脂肽的高产菌株及其制备方法和用途
KR102285335B1 (ko) * 2019-02-14 2021-08-04 주식회사 엠디헬스케어 로치아 속 세균 유래 나노소포 및 이의 용도
TW202045192A (zh) * 2019-02-22 2020-12-16 美商艾弗洛生物科技股份有限公司 細菌膜製劑
CN110195028B (zh) * 2019-03-08 2022-03-01 大连理工大学 一种堆肥低温复合发酵菌剂的制备方法及应用
MY204586A (en) * 2019-04-17 2024-09-05 Biogaia Ab Therapeutic microvesicles of probiotic bacteria
WO2020214961A1 (fr) * 2019-04-17 2020-10-22 Codiak Biosciences, Inc. Méthodes de traitement de la tuberculose
CN111991427A (zh) * 2019-05-07 2020-11-27 瑞微（深圳）生物科技有限公司 肠道细菌在制备用于促进TCR γδ+T细胞增殖的药物中的应用
CN110317744B (zh) * 2019-05-08 2021-11-05 安徽农业大学 一种生产蓝紫色素的马赛菌及其生产蓝紫色素的方法
WO2020252144A1 (fr) * 2019-06-11 2020-12-17 Evelo Biosciences, Inc. Vésicules extracellulaires microbiennes sécrétées
JP2022536806A (ja) 2019-06-20 2022-08-18 ローカス アイピー カンパニー リミテッド ライアビリティ カンパニー エマルサンの増進生産のための、粘液細菌およびアシネトバクターの共培養
CA3147629A1 (fr) 2019-07-19 2021-01-28 Finch Therapeutics Holdings Llc. Methodes et produits destines au traitement de troubles gastro-intestinaux
CN115515610A (zh) * 2019-08-05 2022-12-23 伊夫罗生物科学公司 使用栖组织普雷沃菌治疗银屑病和特应性皮炎的组合物和方法
CN110577910B (zh) * 2019-09-17 2022-02-01 南京农业大学 一种侧孢短芽孢杆菌、抗菌脂肽及其在农业与食品上的应用
AU2020348461B2 (en) * 2019-09-18 2025-06-05 Research Development Foundation Methods and probiotic compositions for the treatment of metabolic diseases and disorders
CN110628862A (zh) * 2019-09-24 2019-12-31 哈尔滨工业大学 一种废水梯级能源回收的自聚集颗粒污泥构建方法
US12616712B2 (en) * 2019-09-25 2026-05-05 Lonza Sales Ag Sting agonist comprising exosomes for treating neuroimmunological disorders
US12280096B2 (en) 2021-07-12 2025-04-22 Penland Foundation Treatments of cancer using nitrous oxide and botulinum toxin
CN110982729A (zh) * 2019-10-23 2020-04-10 江苏省中国科学院植物研究所 一种降解木材加工副产物杨树皮纤维素的复合菌剂
CN110804621A (zh) * 2019-10-31 2020-02-18 郑州大学 一种内源性高表达miRNA的大肠杆菌胞外囊泡的制备方法
US20230081756A1 (en) * 2019-12-31 2023-03-16 Xbiome Inc. Compositions comprising bacterial species and methods related thereto
WO2021137494A1 (fr) * 2020-01-02 2021-07-08 삼육대학교산학협력단 Composition pour la prévention ou le traitement du diabète comprenant une souche de butyricimonas sp. en tant que principe actif
WO2021142279A1 (fr) * 2020-01-10 2021-07-15 Evelo Biosciences, Inc. Compositions et procédés de traitement à l'aide de veillonella parvula
KR20220128638A (ko) * 2020-01-13 2022-09-21 백심 아게 항생제와 조합되는 살모넬라-기반의 dna 백신
TW202140051A (zh) * 2020-01-17 2021-11-01 美商艾弗洛生物科技股份有限公司 具有改善的崩散譜之固體劑型
US20240009256A1 (en) * 2020-02-04 2024-01-11 University Of Louisville Research Foundation, Inc. Use of probiotic bacterium-derived extracellular micro- and/or nanoparticles for the treatment of disease
CN111052997B (zh) * 2020-02-25 2022-07-01 青岛农业大学 一种提高草莓连作障碍抗性生物刺激素的制备及应用方法
US11744866B2 (en) 2020-03-18 2023-09-05 Sabine Hazan Methods of preventing and treating COVID-19 infection with probiotics
US11253534B2 (en) 2020-03-23 2022-02-22 Sabine Hazan Method of preventing COVID-19 infection
US11278520B2 (en) 2020-03-31 2022-03-22 Sabine Hazan Method of preventing COVID-19 infection
US20230158088A1 (en) * 2020-03-26 2023-05-25 Persephone Biosciences, Inc. Compositions for modulating gut microflora populations, enhancing drug potency and treating viral infections, and methods for making and using same
EP4560007A3 (fr) * 2020-04-03 2025-08-13 International N&H Denmark ApS Compositions pour la santé métabolique
EP4133107A1 (fr) * 2020-04-06 2023-02-15 Yeda Research and Development Co. Ltd Méthodes de diagnostic du cancer et de prédiction de la réactivité à une thérapie
KR102273234B1 (ko) * 2020-05-08 2021-07-06 코스맥스 주식회사 코쿠리아 바리안스 균주 및 그의 피부 상태 개선 용도
KR102273232B1 (ko) * 2020-05-08 2021-07-06 코스맥스 주식회사 마이크로코커스 리래 균주 및 그의 피부 상태 개선 용도
CN111560330B (zh) * 2020-05-12 2022-04-26 天津科技大学 一种具有免疫调节、抗炎和抗宫颈癌作用的干酪乳杆菌及应用
GB202007452D0 (en) 2020-05-19 2020-07-01 Microbiotica Ltd Threrapeutic bacterial composition
WO2021242056A1 (fr) * 2020-05-28 2021-12-02 주식회사 바이오뱅크힐링 Souche de l'espèce bifidobacterium et vésicule extracellulaire dérivée de cette dernière, et leurs utilisations anti-inflammatoires et antibactériennes
CN115768448A (zh) * 2020-06-11 2023-03-07 伊夫罗生物科学公司 使用马西里福涅拉氏菌治疗疾病和障碍的组合物和方法
WO2021252861A1 (fr) * 2020-06-11 2021-12-16 Evelo Biosciences, Inc. Compositions et méthodes de traitement de maladies et de troubles à l'aide de mégasphaera sp.
AR122610A1 (es) * 2020-06-11 2022-09-21 Evelo Biosciences Inc Composiciones y métodos para el tratamiento de enfermedades y trastornos usando vesículas extracelulares microbianas de oscillospiraceae
CN115768449A (zh) * 2020-06-11 2023-03-07 伊夫罗生物科学公司 使用Harryflintia Acetispora治疗疾病和障碍的组合物和方法
EP3957316B1 (fr) * 2020-06-16 2024-02-07 MD Healthcare Inc. Composition pour prévenir ou traiter des troubles neurologiques ou mentaux comprenant des vésicules issues de lactobacillus paracasei
AU2021296649A1 (en) * 2020-06-22 2023-02-09 Sl Bigen, Inc. Method and composition for enhancing cancer treatment efficacy of bacteria extracellular vesicles
KR102469138B1 (ko) * 2020-07-07 2022-11-22 주식회사 엘제이바이오 파라클로스트리디움 벤조에리티쿰 ｋｓ３ 균주를 포함하는 가축 사체 분해 촉진용 미생물 제제
CN111743922B (zh) * 2020-07-14 2022-03-29 华熙生物科技股份有限公司 一种提高益生菌在鼻腔中的定植和活性的组合物及在鼻腔护理中的应用
JP2023534834A (ja) * 2020-07-21 2023-08-14 エヴェロ バイオサイエンシズ，インコーポレーテッド 神経炎症性疾患の経口療法薬としてのベイロネラ・パルブラ（Ｖｅｉｌｌｏｎｅｌｌａ ｐａｒｖｕｌａ）株
WO2022029015A2 (fr) * 2020-08-03 2022-02-10 Universiteit Gent Compositions bactériennes présentant une activité anti-inflammatoire
CN111876359A (zh) * 2020-08-04 2020-11-03 榆林沙漠王生物科技有限公司 一种用于蔬菜残体资源化处理的复配菌剂及其制备方法及应用
WO2022035269A1 (fr) * 2020-08-14 2022-02-17 주식회사 고바이오랩 Souche de faecalibacterium prausnitzii et ses utilisations
CN112094820B (zh) * 2020-09-17 2021-12-07 扬州大学 霍氏肠杆菌噬菌体yzu.p.a-5及其应用
MX2023003089A (es) * 2020-09-18 2023-05-09 Evelo Biosciences Inc Formas farmaceuticas solidas de bacterias.
CN112094328A (zh) * 2020-09-21 2020-12-18 华南农业大学 一种空肠弯曲杆菌外膜囊泡的提取及纯化方法
WO2022061123A1 (fr) * 2020-09-21 2022-03-24 Evelo Biosciences, Inc. Formes posologiques solides à profils de désintégration améliorés
CN112094778B (zh) * 2020-09-24 2022-06-24 千禾味业食品股份有限公司 一种魏斯氏菌las1、制备方法及其应用
US20240024377A1 (en) * 2020-10-29 2024-01-25 Evelo Biosciences, Inc. Compositions comprising spirulina components
CN114438235A (zh) * 2020-11-04 2022-05-06 深圳市南山区疾病预防控制中心 一种同时检测嗜低温弓形杆菌及斯氏弓形杆菌的引物探针组件、试剂盒及其应用
JP2023554271A (ja) * 2020-12-08 2023-12-27 エムディー ヘルスケア インコーポレイテッド スフィンゴモナス細菌由来小胞を含む神経疾患または精神疾患の予防または治療用組成物
KR102269962B1 (ko) 2020-12-11 2021-06-28 주식회사 바이오뱅크힐링 유박테리움 리모숨 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
FR3118060B1 (fr) * 2020-12-18 2025-03-14 Univ Bourgogne Utilisation anti-biofilm de vesicules membranaires extracellulaires
WO2022139530A1 (fr) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 Composition destinée à réduire, prévenir ou traiter des maladies auto-immunes comprenant des vésicules extracellulaires dérivées de lactobacillus sakei en tant que principe actif
WO2022139532A1 (fr) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 Composition pour améliorer, prévenir ou traiter une stéatose hépatique, comprenant une vésicule extracellulaire dérivée de weissella hellenica en tant que principe actif
WO2022139531A1 (fr) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 Composition pour améliorer, prévenir ou traiter une stéatose hépatique comprenant des vésicules extracellulaires dérivées de leuconostoc citreum en tant que principe actif
US20240066077A1 (en) * 2020-12-28 2024-02-29 Md Healthcare Inc. Composition for prevention or treatment of neutrophilic pulmonary disease comprising extracellular vesicles derived from micrococcus luteus
WO2022145710A1 (fr) * 2020-12-28 2022-07-07 주식회사 엠디헬스케어 Composition pour la prévention ou le traitement de maladies neuro-développementales, neurologiques ou psychiatriques, comprenant des vésicules extracellulaires dérivées de micrococcus luteus
WO2022145902A1 (fr) * 2020-12-28 2022-07-07 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique destinée à la prévention ou au traitement du cancer, comprenant des nanovésicules dérivées d'une souche de lactobacillus sakei en tant qu'ingrédient actif
WO2022145900A1 (fr) * 2020-12-28 2022-07-07 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique pour la prévention ou le traitement du cancer, comprenant en tant que principe actif des nanovésicules issues d'une souche de weissella cibaria
KR102651196B1 (ko) * 2020-12-28 2024-03-27 주식회사 엠디헬스케어 마이크로코커스 루테우스 유래 세포외 소포를 포함하는 안질환 예방 또는 치료용 조성물
WO2022145901A1 (fr) * 2020-12-28 2022-07-07 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique pour la prévention ou le traitement du cancer comprenant des nanovésicules dérivées d'une souche de lactobacillus fermentum en tant que principe actif
WO2022154149A1 (fr) * 2021-01-14 2022-07-21 (주)엑솔런스 Composition vaccinale utilisant une vésicule extracellulaire
EP4285916A4 (fr) 2021-02-01 2024-12-18 MD Healthcare Inc. Composition comprenant des vésicules dérivées de lactobacillus paracasei pour prévenir, traiter ou soulager des maladies infectieuses virales ou des maladies respiratoires
WO2022177412A1 (fr) * 2021-02-22 2022-08-25 주식회사 리스큐어바이오사이언시스 Composition pharmaceutique pour la prévention ou le traitement du cancer comprenant en tant que principe actif des nanovésicules issues d'une souche de weissella cibaria
US20240148797A1 (en) * 2021-02-26 2024-05-09 Evelo Biosciences, Inc. Compositions and methods for reducing cytokine expression
WO2022191183A1 (fr) * 2021-03-08 2022-09-15 学校法人順天堂 Composition et agent d'amélioration présentant une action d'inhibition de l'inflammation
CA3211621A1 (fr) * 2021-03-12 2022-09-15 Jothi Amaranath Govindan Procedes et utilisations de compositions, de composants ou de metabolites du microbiome pour le traitement de troubles oculaires
WO2022211547A1 (fr) * 2021-04-02 2022-10-06 주식회사 엠디헬스케어 Nanovésicules dérivées de bactéries paracoccus sp. et leur utilisation
CN113186172A (zh) * 2021-04-06 2021-07-30 天津农学院 共表达Apoptin与MEL基因的重组腺病毒及构建方法和应用
WO2022221183A1 (fr) * 2021-04-12 2022-10-20 Evelo Biosciences, Inc. Préparations de vésicules extracellulaires de fournierella
CN113025534B (zh) * 2021-04-26 2022-05-27 佛山市南海东方澳龙制药有限公司 一株具有较强抑菌作用的新种芽孢杆菌x901株及其应用
CN115305211A (zh) * 2021-05-07 2022-11-08 葡萄王生技股份有限公司 益生菌胞外泌体及其用途
US12599625B2 (en) 2021-05-13 2026-04-14 Penland Foundation Treatment of ARDS and other conditions caused by acutely elevated cytokine levels and post ARDS chronic cytokine production using inhaled anesthetics
CN113186134B (zh) * 2021-05-17 2022-11-01 中国科学院水生生物研究所 一种蓝藻气囊提取方法及其应用
CN113122483A (zh) * 2021-05-31 2021-07-16 哈尔滨工业大学 一种玉米秸秆好氧堆肥的快速产热菌剂及其应用
EP4349353A4 (fr) * 2021-06-03 2025-06-25 MD Healthcare Inc. Vésicule dérivée de lactobacillus rhamnosus et ses utilisations
JP7396737B2 (ja) * 2021-06-03 2023-12-12 エムディー ヘルスケア インコーポレイテッド ラクトバチルス・パラカゼイ由来細胞外小胞を含む眼疾患の予防または治療用組成物
EP4349354A1 (fr) * 2021-06-03 2024-04-10 MD Healthcare Inc. Vésicules extracellulaires issues de bactéries lactobacilles et leur utilisation
KR102661178B1 (ko) * 2021-06-03 2024-04-29 주식회사 엠디헬스케어 락토바실러스 파라카세이 유래 세포외소포를 포함하는 안질환 예방 또는 치료용 조성물
US20240261345A1 (en) * 2021-06-07 2024-08-08 Md Healthcare Inc. Composition for preventing or treating inflammatory diseases or cancer, comprising leuconostoc bacteria-derived vesicles
KR102850200B1 (ko) * 2021-06-18 2025-08-27 경북대학교 산학협력단 핵산 백신 제조 및 유전자 전달을 위한 세균 유래 세포밖 소포체의 용도
WO2023010074A1 (fr) * 2021-07-28 2023-02-02 The Texas A&M University System Compositions de vaccin comprenant des souches de brucella et leurs procédés
KR102390775B1 (ko) * 2021-09-06 2022-05-04 한국식품연구원 류코노스톡 슈도메센테로이데스 WiKim0138 균주를 유효성분으로 포함하는 암의 예방 또는 치료용 조성물
KR102390755B1 (ko) * 2021-09-06 2022-04-28 한국식품연구원 웨이셀라 파라메센테로이데스 WiKim0137 균주를 유효성분으로 포함하는 암의 예방 또는 치료용 조성물
KR102558084B1 (ko) * 2021-09-14 2023-07-21 코스맥스 주식회사 두피 마이크로바이옴 콤플렉스 및 그의 모발 또는 두피 상태 개선 용도
CN113999789B (zh) * 2021-09-30 2022-11-15 沈阳农业大学 一株产鲜味肽的嗜盐四联球菌及应用
WO2023062422A1 (fr) * 2021-10-11 2023-04-20 Vastu Vihar Biotech Private Limited Composition anti-inflammatoire et son procédé d'obtention
KR102411242B1 (ko) * 2021-10-18 2022-06-22 큐티스바이오 주식회사 클렙시엘라 아에로제네스의 피부 상태 개선 용도
KR102411241B1 (ko) * 2021-10-18 2022-06-22 큐티스바이오 주식회사 코리네박테리움 상귀니스의 피부 상태 개선 용도
KR102859962B1 (ko) * 2021-10-20 2025-09-18 주식회사 고바이오랩 항암 활성을 갖는 베일로넬라 파르불라 균주를 이용한 암의 완화, 예방 또는 치료용 조성물
KR102739746B1 (ko) * 2021-10-25 2024-12-10 인하대학교 산학협력단 바르토넬라 헨셀라이 유래 세포외 소포체를 이용한 바르토넬라 감염증 진단 방법
WO2023075458A1 (fr) * 2021-10-27 2023-05-04 주식회사 바이오뱅크힐링 Nouvelle souche bactérienne, vésicules dérivées de celle-ci, et utilisation anti-inflammatoire et anti-bactérienne associées
CN114085792B (zh) * 2021-11-17 2023-03-24 哈尔滨医科大学 一种用于防治结肠癌的副干酪乳杆菌及其应用
EP4437083A2 (fr) * 2021-11-22 2024-10-02 International N&H Denmark ApS Compositions pour santé métabolique
KR20240107356A (ko) 2021-11-23 2024-07-09 세일 바이오메디슨스, 인크. 박테리아-유래 지질 조성물 및 이의 용도
WO2023114300A1 (fr) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Préparations de vésicules extracellulaires de bactéries fournierella massiliensis
WO2023114296A2 (fr) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Préparations de vésicules extracellulaires
CA3242398A1 (fr) * 2021-12-15 2023-06-22 Board Of Regents, The University Of Texas System Procedes et compositions pour modifier un microbiome tumoral
CN114369673B (zh) * 2022-01-06 2023-07-14 同济大学 结直肠腺瘤生物标志物、试剂盒及生物标志物的筛选方法
JP2025503054A (ja) * 2022-01-20 2025-01-30 コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー ロセブリア属またはビフィドバクテリウム属由来細胞外小胞を含む、非アルコール性脂肪性肝疾患の予防、改善、または治療用組成物
CN114807032B (zh) * 2022-05-20 2023-09-12 南京大学 地塞米松诱导中性粒细胞产生的细胞外囊泡在制备治疗消炎药物中的应用
KR102509869B1 (ko) * 2022-07-14 2023-03-14 주식회사 엔테로바이옴 아커만시아를 포함하는 탈모 예방 또는 치료용 약학적 조성물
KR102620190B1 (ko) * 2022-08-31 2024-01-04 주식회사 바이오뱅크힐링 아가토박터 렉탈리스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102626400B1 (ko) * 2022-08-31 2024-01-19 주식회사 바이오뱅크힐링 도레아 론기카테나 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102620189B1 (ko) * 2022-08-31 2024-01-04 주식회사 바이오뱅크힐링 블라우티아 브룩킹시 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2024049207A1 (fr) * 2022-08-31 2024-03-07 주식회사 바이오뱅크힐링 Nouvelle souche et vésicules qui en sont issues, et leurs utilisations anti-inflammatoires et antibactériennes
CN115590890B (zh) * 2022-10-19 2026-02-17 中南大学湘雅医院 一种双歧杆菌及其胞外囊泡在制备对抗高脂饮食导致的疾病的制剂中的应用
CN116004440B (zh) * 2022-10-25 2025-06-13 深圳未知君生物科技有限公司 一株粘膜粘液乳杆菌及其在制备治疗癌症的药物中的应用
CN115820840A (zh) * 2022-11-23 2023-03-21 武汉轻工大学 一种副猪嗜血杆菌感染后引起仔猪免疫抑制的分子标记物
CN116509900B (zh) * 2022-12-01 2023-11-10 佛山科学技术学院 益生菌或其细胞外囊泡在制备防治胃溃疡产品中的应用
KR20240114298A (ko) * 2023-01-12 2024-07-23 에스엔제이 파마 인크 감염 저항성 장내 균주 및 그 용도
CN116656583B (zh) * 2023-01-13 2024-06-18 南昌大学 靶向肿瘤的幽门螺杆菌突变株及抗胃癌外膜囊泡组合物
CN118496306A (zh) * 2023-02-14 2024-08-16 南京农业大学 一种利用重组枯草芽孢杆菌制备抗应激肽lgspdvivir的方法及应用
KR102945111B1 (ko) * 2023-02-21 2026-04-03 주식회사 엠디헬스케어 류코노스톡 속 세균 유래 소포를 포함하는 대사질환, 간질환, 또는 근육질환 예방 또는 치료용 조성물
CN116622548B (zh) * 2023-03-31 2024-02-09 吉林农业大学 一株能够预防和或治疗牙周炎的嵴链球菌及其应用
CN116355811B (zh) * 2023-04-26 2025-03-18 南京农业大学 一种食淀粉乳杆菌及其在改善胆汁淤积性肝病中的应用
CN116606766B (zh) * 2023-04-26 2025-02-25 南京农业大学 一种食淀粉乳杆菌胞外囊泡的制备方法及其应用
CN116747245B (zh) * 2023-06-14 2024-06-21 辽宁越秀辉山营养科技有限公司 动物双歧杆菌乳亚种bx-245在抑菌和/或生产功能活性物质中的应用
CN117180317B (zh) * 2023-11-02 2024-01-26 深圳市第二人民医院(深圳市转化医学研究院) 詹氏乳杆菌来源纳米囊泡在制备防治卵巢早衰治疗药物中的应用
CN117402794B (zh) * 2023-12-12 2024-02-27 四川厌氧生物科技有限责任公司 一种加氏乳杆菌及其应用
KR20250104680A (ko) * 2023-12-29 2025-07-08 한국생명공학연구원 잔티노박테리움 속 균주 또는 비올라세인을 포함하는 발모 촉진 또는 탈모 예방 또는 치료용 조성물
WO2025183435A1 (fr) * 2024-02-26 2025-09-04 주식회사 건강약품 Microvésicules dérivées d'infantis, sous-espèce de bifidobacterium longum, et leurs utilisations
WO2025198344A1 (fr) * 2024-03-20 2025-09-25 이화여자대학교 산학협력단 Nouvelles bactéries lactiques et leur utilisation
CN118006515B (zh) * 2024-04-08 2024-06-18 中国农业大学 一株乳酸乳球菌及其在制备治疗牛乳腺炎的药物中的应用
WO2025244670A1 (fr) * 2024-05-23 2025-11-27 Candel Therapeutics, Inc. Méthodes de traitement du cancer du poumon
WO2026021930A2 (fr) 2024-07-24 2026-01-29 Henriques Normark Birgitta Immunisation contre le streptocoque du groupe a (gas)
CN118845855A (zh) * 2024-08-19 2024-10-29 广州医科大学附属第二医院 詹氏乳杆菌来源纳米囊泡在制备预防和/或治疗鼻息肉药物中的应用
CN119530061B (zh) * 2024-11-14 2025-07-25 广东医科大学附属医院 一种肠道微生物组合在制备治疗sle药物中的应用
CN119144523A (zh) * 2024-11-19 2024-12-17 哈尔滨医科大学 一株铅黄肠球菌及其外泌体的应用
CN119752719B (zh) * 2024-12-30 2025-12-16 中国疾病预防控制中心传染病预防控制所 一种纤细副梭菌Pt517及其在制备抗炎或抑菌产品中的应用
CN119932075A (zh) * 2025-01-25 2025-05-06 四川大学 一种携带外源蛋白的重组单增李斯特菌膜囊泡及其制备方法和应用
CN119955687B (zh) * 2025-04-10 2025-07-01 西南民族大学 一株具有益生活性的融合魏斯氏菌dy12及其应用
CN120442727A (zh) * 2025-05-07 2025-08-08 湖南湘农动物药业有限公司 富含有机铜的罗伊氏乳杆菌hadig-lr003后生元的制备及其应用
CN120866469A (zh) * 2025-09-29 2025-10-31 上海交通大学医学院附属仁济医院 一种肠道细菌新生外囊泡的分离检测方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2848965A1 (de) 1978-11-11 1980-05-22 Behringwerke Ag Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
US5322784A (en) 1991-06-05 1994-06-21 The Board Of Trustees Of The University Of Illinois, Urbana-Champaign, Illinois Method and materials for introducing DNA into Prevotella ruminicola
EP1261355B1 (fr) 2000-03-01 2004-12-01 Société des Produits Nestlé S.A. Formulation de carbohydrate (adjuvant prebiotique) destine a augmenter une reponse immune
US6812023B1 (en) 2000-04-27 2004-11-02 Anosys, Inc. Methods of producing membrane vesicles
KR20030024811A (ko) * 2000-07-27 2003-03-26 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신
GB0130123D0 (en) 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
EP1618891A1 (fr) 2003-03-31 2006-01-25 Kirin Beer Kabushiki Kaisha Methode d'induction de differenciation et de proliferation de cellules t regulatrices par un anticorps anti-cd52 et composition medicinale associee
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
US20050100559A1 (en) 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
JP5173194B2 (ja) 2003-12-23 2013-03-27 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
CN110872587A (zh) 2007-05-22 2020-03-10 康乃尔研究基金会有限公司 蛋白质在细菌及其衍生小泡表面展示的组合物和方法及其用途
WO2011027956A2 (fr) 2009-09-04 2011-03-10 주식회사이언메딕스 Vésicules extracellulaires issues de bactéries à gram positif, et modèle de maladie utilisant celles-ci
WO2011027971A2 (fr) 2009-09-01 2011-03-10 주식회사이언메딕스 Vésicules extracellulaires dérivées de la flore intestinale, et procédé de recherche d'un modèle de maladie, d'un vaccin et d'un médicament candidat, et de diagnostic utilisant ce dernier
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
KR101488902B1 (ko) 2009-10-08 2015-02-03 주식회사이언메딕스 실내 공기유래 세포밖 소포체를 포함하는 조성물 및 이의 용도
WO2011053653A2 (fr) 2009-10-30 2011-05-05 Mayo Foundation For Medical Education And Research Préparations à base de prevotella histicola et traitement d'états auto-immuns
KR101629525B1 (ko) 2010-01-11 2016-06-13 이화여자대학교 산학협력단 발효식품에서 유래된 세포밖 소포체를 포함하는 조성물 및 이의 용도
AU2011232421B2 (en) 2010-03-23 2015-08-13 Novartis Ag Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc.
WO2012002760A2 (fr) 2010-07-01 2012-01-05 포항공과대학교 산학협력단 Méthode de diagnostic et de traitement du cancer par des microvésicules cellulaires
WO2012093754A1 (fr) 2011-01-04 2012-07-12 포항공과대학교 산학협력단 Composition comprenant des vésicules extracellulaires provenant de l'intérieur d'un corps de mammifère et utilisation de celle-ci
WO2012093755A1 (fr) 2011-01-04 2012-07-12 포항공과대학교 산학협력단 Composition comprenant des vésicules extracellulaires provenant d'une nourriture fermentée et utilisation de celle-ci
WO2014152484A1 (fr) * 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Microbiote fécal lyophilisé à utiliser dans la transplantation microbienne fécale
CN103561752B (zh) 2011-03-09 2016-04-20 明尼苏达大学评议会 用于移植结肠微生物群的组合物和方法
KR101421779B1 (ko) 2011-04-08 2014-07-28 주식회사이언메딕스 아시네토박터 속 세균유래 세포밖 소포체 및 이의 용도
TWI573590B (zh) 2011-09-20 2017-03-11 雷希爾生藥有限公司 治療自體免疫疾病之組成物及方法
AU2012363033B2 (en) 2011-12-28 2016-06-02 Galectin Therapeutics, Inc. Composition of novel carbohydrate drug for treatment of human diseases
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
US11185562B2 (en) 2013-02-04 2021-11-30 Seres Therapeutics, Inc. Compositions and methods for inhibition of pathogenic bacterial growth
US20160120818A1 (en) 2013-02-07 2016-05-05 Glaxosmithline Biological Sa Pharmaceutical compositions comprising vesicles
US10137157B2 (en) * 2013-06-03 2018-11-27 Proprev Ab Treatment of obesity, the metabolic syndrome, type 2 diabetes, cardiovascular diseases, dementia, alzheimer's disease and inflammatory bowel disease by using at least one bacterial strain from Prevotella
KR101740893B1 (ko) 2014-05-20 2017-06-13 주식회사 엠디헬스케어 Ａｋｋｅｒｍａｎｓｉａ ｍｕｃｉｎｉｐｈｉｌａ 균에서 유래하는 세포밖 소포를 유효성분으로 함유하는 대사질환의 치료 또는 예방용 조성물
US10328159B2 (en) 2014-10-03 2019-06-25 Engenic Molecular Delivery Pty Ltd. Enhanced loading of intact, bacterially derived vesicles with small molecule compounds
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
EP3226875B1 (fr) 2014-12-03 2020-05-27 Capricor, Inc. Procédés de production de formulations d'exosomes stables
KR101726488B1 (ko) 2015-02-23 2017-04-13 이화여자대학교 산학협력단 바실러스 속 세균 유래 세포밖 소포체를 포함하는 임신관련 질환 치료용 조성물
KR20160107632A (ko) 2015-03-04 2016-09-19 포항공과대학교 산학협력단 뉴클레아제가 처리된 세균 유래 세포밖 소포체를 이용한 세균 동정 방법
WO2016144139A2 (fr) 2015-03-11 2016-09-15 주식회사 엠디헬스케어 Composition pour prévenir ou traiter des maladies inflammatoires, comprenant des vésicules extracellulaires dérivées de bactéries d'acide lactique comme principes actifs
WO2016141454A1 (fr) * 2015-03-12 2016-09-15 The University Of British Columbia Compositions bactériennes et leurs procédés d'utilisation
KR102394638B1 (ko) 2015-09-30 2022-05-09 (주)아모레퍼시픽 유산균 유래의 세포외 소낭을 포함하는 탈모 방지 또는 육모 촉진용 조성물
US20170145061A1 (en) 2015-11-20 2017-05-25 Massachusetts Institute Of Technology Engineered bacteroides outer membrane vesicles
WO2017123025A1 (fr) 2016-01-15 2017-07-20 주식회사 엠디헬스케어 Régulateur pour troubles de la fonction immunitaire des voies respiratoires, utilisant des vésicules extracellulaires d'origine bactérienne
US10722543B2 (en) 2016-01-28 2020-07-28 Oxyrase, Inc. Methods for inhibiting tumor growth using anaerobe microorganisms
EP3520801A1 (fr) 2016-03-04 2019-08-07 4D Pharma Plc Compositions comprenant des souches bactériennes de blautia pour le traitement de l'hypersensibilité viscérale
CN111526881A (zh) 2017-09-08 2020-08-11 伊夫罗生物科学公司 来自普雷沃菌的胞外囊泡
CN111148531A (zh) 2017-09-08 2020-05-12 伊夫罗生物科学公司 细菌胞外囊泡

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US11524037B2 (en) 2022-12-13
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JP2020533290A (ja) 2020-11-19
US20200254028A1 (en) 2020-08-13
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AR113011A1 (es) 2020-01-15
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