MA50536A - Nouvelles formes solides de squalamine et procédés pour les produire - Google Patents

Nouvelles formes solides de squalamine et procédés pour les produire

Info

Publication number: MA50536A
Authority: MA; Morocco
Prior art keywords: squalamine; processes; producing; solid forms; new solid
Prior art date: 2017-10-30

Application number

MA050536A

Other languages

English (en)

Inventor

William A Kinney

Anil Kumar

Michael Zasloff

Amanuel Z Zelellow

Dalian Zhao

Original Assignee

Enterin Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-10-30

Filing date

2018-10-26

Publication date

2020-09-09

2018-10-26 Application filed by Enterin Inc filed Critical Enterin Inc

2020-09-09 Publication of MA50536A publication Critical patent/MA50536A/fr

Links

UIRKNQLZZXALBI-MSVGPLKSSA-N Squalamine Chemical compound C([C@@H]1C[C@H]2O)[C@@H](NCCCNCCCCN)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@H](C(C)C)OS(O)(=O)=O)[C@@]2(C)CC1 UIRKNQLZZXALBI-MSVGPLKSSA-N 0.000 title 1
UIRKNQLZZXALBI-UHFFFAOYSA-N Squalamine Natural products OC1CC2CC(NCCCNCCCCN)CCC2(C)C2C1C1CCC(C(C)CCC(C(C)C)OS(O)(=O)=O)C1(C)CC2 UIRKNQLZZXALBI-UHFFFAOYSA-N 0.000 title 1
239000007787 solid Substances 0.000 title 1
229950001248 squalamine Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Biotechnology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MA050536A 2017-10-30 2018-10-26 Nouvelles formes solides de squalamine et procédés pour les produire MA50536A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201762579084P	2017-10-30	2017-10-30

Publications (1)

Publication Number	Publication Date
MA50536A true MA50536A (fr)	2020-09-09

Family

ID=66245247

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA050536A MA50536A (fr)	2017-10-30	2018-10-26	Nouvelles formes solides de squalamine et procédés pour les produire

Country Status (4)

Country	Link
US (2)	US11066438B2 (fr)
EP (1)	EP3704132A4 (fr)
MA (1)	MA50536A (fr)
WO (1)	WO2019089365A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20200146038A (ko) *	2018-03-27	2020-12-31	엔테린, 인코포레이티드	환각 및 이와 관련된 상태를 치료하는 방법 및 조성물
WO2020028810A1 (fr) *	2018-08-03	2020-02-06	Enterin Laboratories	Compositions et méthodes pour traiter des troubles de l'axe intestin-cerveau
CN115551871A (zh) *	2020-03-19	2022-12-30	因特尔公司	角鲨胺的晶型

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3773919A (en)	1969-10-23	1973-11-20	Du Pont	Polylactide-drug mixtures
US4263428A (en)	1978-03-24	1981-04-21	The Regents Of The University Of California	Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
DE3169595D1 (en)	1980-11-10	1985-05-02	Gersonde Klaus	Method of preparing lipid vesicles by ultrasonic treatment, the use of this method and apparatus for its application
IE52535B1 (en)	1981-02-16	1987-12-09	Ici Plc	Continuous release pharmaceutical compositions
US4485045A (en)	1981-07-06	1984-11-27	Research Corporation	Synthetic phosphatidyl cholines useful in forming liposomes
EP0088046B1 (fr)	1982-02-17	1987-12-09	Ciba-Geigy Ag	Lipides en phase aqueuse
DE3218121A1 (de)	1982-05-14	1983-11-17	Leskovar, Peter, Dr.-Ing., 8000 München	Arzneimittel zur tumorbehandlung
EP0102324A3 (fr)	1982-07-29	1984-11-07	Ciba-Geigy Ag	Lipides et composés tensio-actifs en phase aqueuse
US4544545A (en)	1983-06-20	1985-10-01	Trustees University Of Massachusetts	Liposomes containing modified cholesterol for organ targeting
HUT35524A (en)	1983-08-02	1985-07-29	Hoechst Ag	Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
DE3486459D1 (de)	1983-09-26	1997-12-11	Udo Dr Med Ehrenfeld	Mittel und Erzeugnis für die Diagnose und Therapie von Tumoren sowie zur Behandlung von Schwächen der zelligen und humoralen Immunabwehr
EP0143949B1 (fr)	1983-11-01	1988-10-12	TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION	Composition pharmaceutique contenant de l'urokinase
US5192756A (en)	1992-03-18	1993-03-09	The Children's Hospital Of Pennsylvania	Aminosterol antibiotic
US6140368A (en)	1997-05-05	2000-10-31	The Regents Of The University Of California	Naphthols useful in antiviral methods
US6071743A (en)	1997-06-02	2000-06-06	Subsidiary No. 3, Inc.	Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes
US7981876B2 (en)	2005-04-25	2011-07-19	Ohr Pharmaceuticals, Inc.	Polymorphic and amorphous salt forms of squalamine dilactate
WO2011056650A2 (fr)	2009-10-27	2011-05-12	Michael Zasloff	Méthodes et compositions utilisées dans le cadre du traitement et de la prévention d'infections virales
WO2011066260A2 (fr) *	2009-11-25	2011-06-03	Michael Zasloff	Formulations comprenant des aminostérols
US10040817B2 (en) *	2013-10-03	2018-08-07	Enterin Laboratories, Inc.	Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same

2018
- 2018-10-26 MA MA050536A patent/MA50536A/fr unknown
- 2018-10-26 WO PCT/US2018/057650 patent/WO2019089365A1/fr not_active Ceased
- 2018-10-26 US US16/172,204 patent/US11066438B2/en not_active Expired - Fee Related
- 2018-10-26 EP EP18874567.3A patent/EP3704132A4/fr not_active Withdrawn
2021
- 2021-07-01 US US17/365,208 patent/US20210332079A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20190127416A1 (en)	2019-05-02
US11066438B2 (en)	2021-07-20
EP3704132A4 (fr)	2021-07-28
US20210332079A1 (en)	2021-10-28
WO2019089365A1 (fr)	2019-05-09
EP3704132A1 (fr)	2020-09-09

Publication	Publication Date	Title
EP3706784A4 (fr)	2021-12-01	Compositions et procédés de production de lymphocytes t
IL261427A (en)	2018-10-31	Method and apparatus to determine a patterning process parameter
EP3625229A4 (fr)	2021-03-03	Formes solides de berbérine ursodésoxycholate, compositions et procédés associés
EP3503901A4 (fr)	2020-02-26	Procédés et compositions pour cellules de moelle épinière
EP3294865A4 (fr)	2019-06-26	Procédés de production d'épimérases et d'alcaloïdes benzylisoquinoléine
EP3604515A4 (fr)	2021-01-06	Composition pour la production de tagatose et procédé de production de tagatose l'utilisant
MA42829A (fr)	2021-04-14	Compositions dérivées de placenta et procédés pour les produire
EP3632550A4 (fr)	2021-03-03	Structure fonctionnelle et procédé de production pour structure fonctionnelle
SG10202010155YA (en)	2020-11-27	Compositions and methods for making antibodies based on use of expression-enhancing loci
EP3522934A4 (fr)	2020-04-15	Compositions et méthode pour le traitement de la rénopathie
MA46972A (fr)	2019-10-09	Forme polymorphe de sépiaptérine
EP3604514A4 (fr)	2021-01-20	Composition pour la production de tagatose et procédé pour la production de tagatose utilisant celle-ci
EP3562505A4 (fr)	2020-11-11	Anticorps anti-vih-1 largement neutralisants et leurs procédé d'utilisation
EP3735457A4 (fr)	2021-08-25	Compositions et procédés pour produire des mégacaryocytes
EP3604516A4 (fr)	2021-01-20	Composition pour la production de tagatose et procédé de production de tagatose la mettant en oeuvre
EP3640302A4 (fr)	2021-03-17	Composition de silicone et procédé de production de cette dernière
EP3429609A4 (fr)	2019-10-16	Compositions et procédés pour le traitement de déficits en collagène de type vii
EP3509737A4 (fr)	2020-08-19	Procédés d'alcoxylation continue et de dérivation de terpènes
EP3619334A4 (fr)	2020-12-02	Procédé de dépôt d'alliages de nickel-molybdène-tungstène nanomaclés
EP3710092A4 (fr)	2021-01-06	Toile et procédé pour la fabriquer
EP3569689A4 (fr)	2020-11-11	Composition de cryoconservation de cellules et procédé de cryoconservation
IL284327A (en)	2021-08-31	Compositions and methods for inhibiting hmgb1 expression
EP3585822A4 (fr)	2021-03-03	Procédés de production de compositions de polyisobutylène
EP3808424A4 (fr)	2021-07-28	Cristalliseur et procédé de cristallisation
EP3480810A4 (fr)	2020-02-26	Dispositif de synthèse vocale et procédé de synthèse vocale