MA51146A - SUBSTITUTED HETEROCYCLIC BICYCLIC COMPOUNDS USED AS PRMT5 INHIBITORS - Google Patents

SUBSTITUTED HETEROCYCLIC BICYCLIC COMPOUNDS USED AS PRMT5 INHIBITORS

Info

Publication number
MA51146A
MA51146A MA051146A MA51146A MA51146A MA 51146 A MA51146 A MA 51146A MA 051146 A MA051146 A MA 051146A MA 51146 A MA51146 A MA 51146A MA 51146 A MA51146 A MA 51146A
Authority
MA
Morocco
Prior art keywords
substituted heterocyclic
compounds used
bicyclic compounds
heterocyclic bicyclic
prmt5 inhibitors
Prior art date
Application number
MA051146A
Other languages
French (fr)
Other versions
MA51146B1 (en
Inventor
Balasaheb Arjun Gore
Ganesh Bhausaheb Gudade
Anil Kashiram Hajare
Rajender Kumar Kamboj
Chaitanya Prabhakar Kulkarni
Sanjeev Anant Kulkarni
Dipak Raychand Lagad
Prathap Sreedharan Nair
Venkata P Palle
Chetan Sanjay Pawar
Sachin Sethi
Milind Dattatraya Sindkhedkar
Mahadeo Bhaskar Tryambake
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Priority claimed from PCT/IB2018/060015 external-priority patent/WO2019116302A1/en
Publication of MA51146A publication Critical patent/MA51146A/en
Publication of MA51146B1 publication Critical patent/MA51146B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA51146A 2017-12-13 2018-12-13 Bicyclic substituted heterocyclic compounds used as prmt5 inhibitors MA51146B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201721044886 2017-12-13
PCT/IB2018/060015 WO2019116302A1 (en) 2017-12-13 2018-12-13 Substituted bicyclic heterocyclic compounds as prmt5 inhibitors

Publications (2)

Publication Number Publication Date
MA51146A true MA51146A (en) 2021-03-24
MA51146B1 MA51146B1 (en) 2022-10-31

Family

ID=83995765

Family Applications (1)

Application Number Title Priority Date Filing Date
MA51146A MA51146B1 (en) 2017-12-13 2018-12-13 Bicyclic substituted heterocyclic compounds used as prmt5 inhibitors

Country Status (1)

Country Link
MA (1) MA51146B1 (en)

Also Published As

Publication number Publication date
MA51146B1 (en) 2022-10-31

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