MA51287A - Analogues d'incrétine et leurs utilisations - Google Patents

Analogues d'incrétine et leurs utilisations

Info

Publication number
MA51287A
MA51287A MA051287A MA51287A MA51287A MA 51287 A MA51287 A MA 51287A MA 051287 A MA051287 A MA 051287A MA 51287 A MA51287 A MA 51287A MA 51287 A MA51287 A MA 51287A
Authority
MA
Morocco
Prior art keywords
incretin
analogues
incretin analogues
Prior art date
Application number
MA051287A
Other languages
English (en)
Inventor
Jorge Alsina-Fernandez
Tamer Coskun
Lili Guo
Hongchang Qu
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA51287A publication Critical patent/MA51287A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Details Of Garments (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
MA051287A 2017-12-21 2018-12-14 Analogues d'incrétine et leurs utilisations MA51287A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762608644P 2017-12-21 2017-12-21

Publications (1)

Publication Number Publication Date
MA51287A true MA51287A (fr) 2021-03-31

Family

ID=65003515

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051287A MA51287A (fr) 2017-12-21 2018-12-14 Analogues d'incrétine et leurs utilisations

Country Status (26)

Country Link
US (2) US11834486B2 (fr)
EP (1) EP3727425A1 (fr)
JP (2) JP6987993B2 (fr)
KR (1) KR102440323B1 (fr)
CN (1) CN111511387A (fr)
AR (1) AR113487A1 (fr)
AU (1) AU2018388895B2 (fr)
BR (1) BR112020010410A2 (fr)
CA (1) CA3084004C (fr)
CL (1) CL2020001636A1 (fr)
CO (1) CO2020006253A2 (fr)
CR (1) CR20200256A (fr)
DO (1) DOP2020000124A (fr)
EA (1) EA202091284A1 (fr)
EC (1) ECSP20032306A (fr)
IL (2) IL325352A (fr)
JO (1) JOP20200136B1 (fr)
MA (1) MA51287A (fr)
MX (2) MX2020006547A (fr)
MY (1) MY199545A (fr)
PE (1) PE20200926A1 (fr)
PH (1) PH12020551024A1 (fr)
SG (1) SG11202004359YA (fr)
TW (2) TWI810937B (fr)
UA (1) UA127589C2 (fr)
WO (1) WO2019125929A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI912614B (zh) * 2017-12-21 2026-01-21 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
TWI810937B (zh) * 2017-12-21 2023-08-01 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
ES3068975T3 (en) * 2018-07-23 2026-06-03 Lilly Co Eli Gip/glp1 co-agonist compounds
AR119471A1 (es) * 2019-08-01 2021-12-22 Lilly Co Eli Compuestos agonistas de gipr
WO2021034815A1 (fr) * 2019-08-19 2021-02-25 Eli Lilly And Company Procédés de fabrication d'analogues d'incrétine
AR120714A1 (es) 2019-12-18 2022-03-09 Lilly Co Eli Análogos de incretina y sus usos
CA3165430A1 (fr) * 2020-01-23 2021-07-29 Jorge Alsina-Fernandez Composes co-agonistes de gip/glp1
US20230310630A1 (en) * 2020-07-17 2023-10-05 Hanmi Pharm. Co., Ltd. Therapeutic use of combination comprising triple agonistic long-acting conjugate or triple agonist
JP2023537895A (ja) * 2020-08-14 2023-09-06 ハンミ ファーマシューティカル カンパニー リミテッド 三重活性体持続型結合体を有効成分として含む薬学組成物
WO2022090447A1 (fr) 2020-10-30 2022-05-05 Novo Nordisk A/S Agonistes triples du récepteur de glp-1, gip et glucagon
TW202423476A (zh) 2021-03-23 2024-06-16 美商美國禮來大藥廠 含腸促胰島素(incretin)類似物之組合物及其用途
CA3219647A1 (fr) * 2021-05-26 2022-12-01 The United Bio-Technology (Hengqin) Co., Ltd. Multiagonistes et utilisation connexe
WO2022268029A1 (fr) * 2021-06-21 2022-12-29 广东东阳光药业有限公司 Agoniste triple pour récepteurs glp-1, gcg et gip
AU2022298662B2 (en) 2021-06-23 2025-06-05 Eli Lilly And Company An incretin analog for use in glycemic control and weight management
KR20240099485A (ko) * 2021-11-19 2024-06-28 메드샤인 디스커버리 아이엔씨. 스테이플화 펩타이드 및 이의 용도
CN116162147B (zh) * 2021-11-24 2023-10-03 成都奥达生物科技有限公司 一种长效胰岛素类似物
CN117417411B (zh) * 2022-09-28 2025-08-29 广东东阳光药业股份有限公司 Glp-1/gcg/gip三受体激动剂及其用途
CN121001710A (zh) 2022-12-30 2025-11-21 阿尔吉法玛公司 提高口服多肽治疗剂的全身生物利用度的组合物和方法
AU2024215381A1 (en) 2023-01-31 2025-09-18 Eli Lilly And Company Gip/glp1/gcg tri-receptor agonists and uses thereof
WO2024213022A1 (fr) * 2023-04-11 2024-10-17 上海多米瑞生物技术有限公司 Analogues d'incrétine et leur procédé de préparation, et utilisation
CN120329412A (zh) * 2023-11-06 2025-07-18 成都奥达生物科技有限公司 一种三激动剂化合物
CN120349393A (zh) * 2023-11-06 2025-07-22 成都奥达生物科技有限公司 一种三激动剂化合物
CN119241684B (zh) * 2024-11-22 2025-02-25 徐州医科大学 一种肠促胰岛素类似物及其用途
GB202418179D0 (en) 2024-12-11 2025-01-22 Algipharma As Compositions and methods
GB202418172D0 (en) 2024-12-11 2025-01-22 Algipharma As Compositions and methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8779103B2 (en) 2009-03-27 2014-07-15 Glaxo Group Limited Drug fusions and conjugates
AR092873A1 (es) * 2012-09-26 2015-05-06 Cadila Healthcare Ltd Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
AU2014345570B2 (en) * 2013-11-06 2019-01-24 Zealand Pharma A/S Glucagon-GLP-1-GIP triple agonist compounds
CA2929459C (fr) 2013-11-06 2022-05-03 Zealand Pharma A/S Composes agonistes doubles de gip et glp-1 et procedes associes
AR103242A1 (es) 2015-01-09 2017-04-26 Lilly Co Eli Compuestos co-agonistas de gip y glp-1
WO2016198624A1 (fr) 2015-06-12 2016-12-15 Sanofi Dérivés d'exendine 4 utilisés en tant qu'agonistes trigonaux des récepteurs du glp-1/glucagon/gip
TWI783244B (zh) 2015-06-22 2022-11-11 美商美國禮來大藥廠 升糖素及glp-1共激動劑化合物
JP6712323B2 (ja) 2015-12-31 2020-06-17 ハンミ ファーマシューティカル カンパニー リミテッド グルカゴン、glp−1及びgip受容体のすべてに活性を有する三重活性体
EP3217027A1 (fr) 2016-03-08 2017-09-13 HILTI Aktiengesellschaft Élement de revetement large destine a entourer une tige d'ancrage
TWI810937B (zh) * 2017-12-21 2023-08-01 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途

Also Published As

Publication number Publication date
JP2022043082A (ja) 2022-03-15
US11834486B2 (en) 2023-12-05
US20210221865A1 (en) 2021-07-22
JOP20200136B1 (ar) 2024-04-18
US20240190936A1 (en) 2024-06-13
CO2020006253A2 (es) 2020-05-29
CA3084004A1 (fr) 2019-06-27
AU2018388895A1 (en) 2020-06-04
IL275469B1 (en) 2026-01-01
TWI767095B (zh) 2022-06-11
IL325352A (en) 2026-02-01
IL275469A (en) 2020-08-31
SG11202004359YA (en) 2020-06-29
TW202233227A (zh) 2022-09-01
AU2018388895B2 (en) 2020-12-24
JP2021506825A (ja) 2021-02-22
MX2020006547A (es) 2020-12-09
ECSP20032306A (es) 2020-07-31
EA202091284A1 (ru) 2020-09-08
BR112020010410A2 (pt) 2020-11-24
CL2020001636A1 (es) 2020-10-16
AR113487A1 (es) 2020-05-06
TWI810937B (zh) 2023-08-01
PH12020551024A1 (en) 2021-05-31
CR20200256A (es) 2020-07-12
MX2025003745A (es) 2025-05-02
UA127589C2 (uk) 2023-10-25
PE20200926A1 (es) 2020-09-14
TW201938187A (zh) 2019-10-01
JOP20200136A1 (ar) 2022-10-30
EP3727425A1 (fr) 2020-10-28
IL275469B2 (en) 2026-05-01
KR20200088418A (ko) 2020-07-22
CN111511387A (zh) 2020-08-07
MY199545A (en) 2023-11-06
WO2019125929A1 (fr) 2019-06-27
KR102440323B1 (ko) 2022-09-05
DOP2020000124A (es) 2020-08-31
CA3084004C (fr) 2023-06-20
JP6987993B2 (ja) 2022-01-05
NZ765268A (en) 2024-07-05

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