MA51287A - Analogues d'incrétine et leurs utilisations - Google Patents

Analogues d'incrétine et leurs utilisations

Info

Publication number
MA51287A
MA51287A MA051287A MA51287A MA51287A MA 51287 A MA51287 A MA 51287A MA 051287 A MA051287 A MA 051287A MA 51287 A MA51287 A MA 51287A MA 51287 A MA51287 A MA 51287A
Authority
MA
Morocco
Prior art keywords
incretin
analogues
incretin analogues
Prior art date
Application number
MA051287A
Other languages
English (en)
Inventor
Jorge Alsina-Fernandez
Tamer Coskun
Lili Guo
Hongchang Qu
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA51287A publication Critical patent/MA51287A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Details Of Garments (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Medicinal Preparation (AREA)
MA051287A 2017-12-21 2018-12-14 Analogues d'incrétine et leurs utilisations MA51287A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762608644P 2017-12-21 2017-12-21

Publications (1)

Publication Number Publication Date
MA51287A true MA51287A (fr) 2021-03-31

Family

ID=65003515

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051287A MA51287A (fr) 2017-12-21 2018-12-14 Analogues d'incrétine et leurs utilisations

Country Status (26)

Country Link
US (2) US11834486B2 (fr)
EP (1) EP3727425A1 (fr)
JP (2) JP6987993B2 (fr)
KR (1) KR102440323B1 (fr)
CN (1) CN111511387A (fr)
AR (1) AR113487A1 (fr)
AU (1) AU2018388895B2 (fr)
BR (1) BR112020010410A2 (fr)
CA (1) CA3084004C (fr)
CL (1) CL2020001636A1 (fr)
CO (1) CO2020006253A2 (fr)
CR (1) CR20200256A (fr)
DO (1) DOP2020000124A (fr)
EA (1) EA202091284A1 (fr)
EC (1) ECSP20032306A (fr)
IL (2) IL275469B2 (fr)
JO (1) JOP20200136B1 (fr)
MA (1) MA51287A (fr)
MX (2) MX2020006547A (fr)
MY (1) MY199545A (fr)
PE (1) PE20200926A1 (fr)
PH (1) PH12020551024A1 (fr)
SG (1) SG11202004359YA (fr)
TW (2) TWI810937B (fr)
UA (1) UA127589C2 (fr)
WO (1) WO2019125929A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI810937B (zh) * 2017-12-21 2023-08-01 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
TWI744579B (zh) * 2017-12-21 2021-11-01 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
TWI735917B (zh) 2018-07-23 2021-08-11 美商美國禮來大藥廠 Gip/glp1共促效劑化合物
AR119471A1 (es) * 2019-08-01 2021-12-22 Lilly Co Eli Compuestos agonistas de gipr
EP4017866A1 (fr) 2019-08-19 2022-06-29 Eli Lilly and Company Procédés de fabrication d'analogues d'incrétine
AR120714A1 (es) * 2019-12-18 2022-03-09 Lilly Co Eli Análogos de incretina y sus usos
IL294955A (en) * 2020-01-23 2022-09-01 Lilly Co Eli Cobalt-agonist gip/glp1 compounds
EP4183419A4 (fr) * 2020-07-17 2025-04-02 Hanmi Pharm. Co., Ltd. Utilisation thérapeutique d'une combinaison contenant un conjugué à action prolongée triplement agoniste ou un triple agoniste
IL299800A (en) * 2020-08-14 2023-03-01 Hanmi Pharm Ind Co Ltd Pharmaceutical compositions containing long-acting conjugates of a triple agonist of the GLP-1/GIP glucagon receptor
WO2022090447A1 (fr) 2020-10-30 2022-05-05 Novo Nordisk A/S Agonistes triples du récepteur de glp-1, gip et glucagon
TW202423476A (zh) 2021-03-23 2024-06-16 美商美國禮來大藥廠 含腸促胰島素(incretin)類似物之組合物及其用途
JP7803570B2 (ja) * 2021-05-26 2026-01-21 ザ ユナイテッド バイオテクノロジー(ヘンチン)シーオー.,エルティーディー. マルチアゴニストおよびその使用
CN115572326B (zh) * 2021-06-21 2025-01-10 广东东阳光药业股份有限公司 Glp-1、gcg和gip受体的三重激动剂
BR112023027321A2 (pt) 2021-06-23 2024-03-12 Lilly Co Eli Uso de um polipeptídeo, composição que compreende trirreceptor ggg, e dispositivo
EP4434536A4 (fr) * 2021-11-19 2026-01-07 Jiangsu Deyuan Pharmaceutical Co Ltd Peptide agrafé et son utilisation
CN116162147B (zh) * 2021-11-24 2023-10-03 成都奥达生物科技有限公司 一种长效胰岛素类似物
AU2023348864A1 (en) * 2022-09-28 2025-03-20 Sunshine Lake Pharma Co., Ltd. Glp-1/gcg/gip triple-receptor agonist and use thereof
JP2026502943A (ja) 2022-12-30 2026-01-27 アルギファルマ エーエス 経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法
IL322205A (en) 2023-01-31 2025-09-01 Lilly Co Eli GIP/GLP1/GCG trireceptor agonists and their uses
WO2024213022A1 (fr) * 2023-04-11 2024-10-17 上海多米瑞生物技术有限公司 Analogues d'incrétine et leur procédé de préparation, et utilisation
CN120349393A (zh) * 2023-11-06 2025-07-22 成都奥达生物科技有限公司 一种三激动剂化合物
CN120329412A (zh) * 2023-11-06 2025-07-18 成都奥达生物科技有限公司 一种三激动剂化合物
CN119241684B (zh) * 2024-11-22 2025-02-25 徐州医科大学 一种肠促胰岛素类似物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20120514A1 (es) 2009-03-27 2012-05-14 Glaxo Group Ltd Fusiones y conjugados de agentes insulinotropicos o farmacos incretina con anticuerpos dab anti-albumina serica
AR092873A1 (es) 2012-09-26 2015-05-06 Cadila Healthcare Ltd Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
AU2014345569B2 (en) 2013-11-06 2020-08-13 Zealand Pharma A/S GIP-GLP-1 dual agonist compounds and methods
KR102310392B1 (ko) * 2013-11-06 2021-10-13 질랜드 파마 에이/에스 글루카곤-glp-1-gip 삼원 효능제 화합물
JO3575B1 (ar) * 2015-01-09 2020-07-05 Lilly Co Eli مركبات مساعد مشترك من gip وglp-1
WO2016198624A1 (fr) 2015-06-12 2016-12-15 Sanofi Dérivés d'exendine 4 utilisés en tant qu'agonistes trigonaux des récepteurs du glp-1/glucagon/gip
AR104932A1 (es) * 2015-06-22 2017-08-23 Lilly Co Eli Compuestos co-agonistas del glucagón y péptido-1 similar al glugacón (glp-1)
JP6712323B2 (ja) 2015-12-31 2020-06-17 ハンミ ファーマシューティカル カンパニー リミテッド グルカゴン、glp−1及びgip受容体のすべてに活性を有する三重活性体
EP3217027A1 (fr) 2016-03-08 2017-09-13 HILTI Aktiengesellschaft Élement de revetement large destine a entourer une tige d'ancrage
TWI810937B (zh) * 2017-12-21 2023-08-01 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途

Also Published As

Publication number Publication date
AR113487A1 (es) 2020-05-06
KR20200088418A (ko) 2020-07-22
MX2020006547A (es) 2020-12-09
CN111511387A (zh) 2020-08-07
PE20200926A1 (es) 2020-09-14
UA127589C2 (uk) 2023-10-25
AU2018388895B2 (en) 2020-12-24
JOP20200136A1 (ar) 2022-10-30
JOP20200136B1 (ar) 2024-04-18
CA3084004C (fr) 2023-06-20
MY199545A (en) 2023-11-06
NZ765268A (en) 2024-07-05
MX2025003745A (es) 2025-05-02
TW201938187A (zh) 2019-10-01
IL275469B2 (en) 2026-05-01
JP2022043082A (ja) 2022-03-15
CL2020001636A1 (es) 2020-10-16
PH12020551024A1 (en) 2021-05-31
CR20200256A (es) 2020-07-12
IL275469A (en) 2020-08-31
BR112020010410A2 (pt) 2020-11-24
US20240190936A1 (en) 2024-06-13
US11834486B2 (en) 2023-12-05
US20210221865A1 (en) 2021-07-22
TW202233227A (zh) 2022-09-01
DOP2020000124A (es) 2020-08-31
EP3727425A1 (fr) 2020-10-28
AU2018388895A1 (en) 2020-06-04
TWI810937B (zh) 2023-08-01
TWI767095B (zh) 2022-06-11
CA3084004A1 (fr) 2019-06-27
IL275469B1 (en) 2026-01-01
EA202091284A1 (ru) 2020-09-08
WO2019125929A1 (fr) 2019-06-27
CO2020006253A2 (es) 2020-05-29
JP2021506825A (ja) 2021-02-22
KR102440323B1 (ko) 2022-09-05
JP6987993B2 (ja) 2022-01-05
IL325352A (en) 2026-02-01
ECSP20032306A (es) 2020-07-31
SG11202004359YA (en) 2020-06-29

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