MA51287A - Analogues d'incrétine et leurs utilisations - Google Patents

Analogues d'incrétine et leurs utilisations

Info

Publication number
MA51287A
MA51287A MA051287A MA51287A MA51287A MA 51287 A MA51287 A MA 51287A MA 051287 A MA051287 A MA 051287A MA 51287 A MA51287 A MA 51287A MA 51287 A MA51287 A MA 51287A
Authority
MA
Morocco
Prior art keywords
incretin
analogues
incretin analogues
Prior art date
Application number
MA051287A
Other languages
English (en)
Inventor
Jorge Alsina-Fernandez
Tamer Coskun
Lili Guo
Hongchang Qu
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA51287A publication Critical patent/MA51287A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Details Of Garments (AREA)
  • Medicinal Preparation (AREA)
MA051287A 2017-12-21 2018-12-14 Analogues d'incrétine et leurs utilisations MA51287A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762608644P 2017-12-21 2017-12-21

Publications (1)

Publication Number Publication Date
MA51287A true MA51287A (fr) 2021-03-31

Family

ID=65003515

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051287A MA51287A (fr) 2017-12-21 2018-12-14 Analogues d'incrétine et leurs utilisations

Country Status (26)

Country Link
US (2) US11834486B2 (fr)
EP (1) EP3727425A1 (fr)
JP (2) JP6987993B2 (fr)
KR (1) KR102440323B1 (fr)
CN (1) CN111511387A (fr)
AR (1) AR113487A1 (fr)
AU (1) AU2018388895B2 (fr)
BR (1) BR112020010410A2 (fr)
CA (1) CA3084004C (fr)
CL (1) CL2020001636A1 (fr)
CO (1) CO2020006253A2 (fr)
CR (1) CR20200256A (fr)
DO (1) DOP2020000124A (fr)
EA (1) EA202091284A1 (fr)
EC (1) ECSP20032306A (fr)
IL (2) IL325352A (fr)
JO (1) JOP20200136B1 (fr)
MA (1) MA51287A (fr)
MX (2) MX2020006547A (fr)
MY (1) MY199545A (fr)
PE (1) PE20200926A1 (fr)
PH (1) PH12020551024A1 (fr)
SG (1) SG11202004359YA (fr)
TW (2) TWI767095B (fr)
UA (1) UA127589C2 (fr)
WO (1) WO2019125929A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI767095B (zh) * 2017-12-21 2022-06-11 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
AR113486A1 (es) * 2017-12-21 2020-05-06 Lilly Co Eli Análogos de incretina y sus usos
KR20240051304A (ko) * 2018-07-23 2024-04-19 일라이 릴리 앤드 캄파니 Gip/glp1 공효능제 화합물
AR119471A1 (es) 2019-08-01 2021-12-22 Lilly Co Eli Compuestos agonistas de gipr
KR102812908B1 (ko) 2019-08-19 2025-05-28 일라이 릴리 앤드 캄파니 인크레틴 유사체의 제조 방법
AR120714A1 (es) * 2019-12-18 2022-03-09 Lilly Co Eli Análogos de incretina y sus usos
IL294955A (en) * 2020-01-23 2022-09-01 Lilly Co Eli Cobalt-agonist gip/glp1 compounds
JP2023535382A (ja) * 2020-07-17 2023-08-17 ハンミ ファーマシューティカル カンパニー リミテッド 三重作用性持続型結合体又は三重作用剤を含む組合せ物の治療学的用途
EP4197560A4 (fr) * 2020-08-14 2025-11-26 Hanmi Pharmaceutical Co Ltd Composition pharmaceutique comprenant un conjugué persistant de triple activateur utilisé comme principe actif
US20230391845A1 (en) 2020-10-30 2023-12-07 Novo Nordisk A/S Glp-1, gip and glucagon receptor triple agonists
TWI837615B (zh) 2021-03-23 2024-04-01 美商美國禮來大藥廠 含腸促胰島素(incretin)類似物之組合物及其用途
WO2022247701A1 (fr) 2021-05-26 2022-12-01 联邦生物科技(珠海横琴)有限公司 Multi-agoniste et son utilisation
WO2022268029A1 (fr) * 2021-06-21 2022-12-29 广东东阳光药业有限公司 Agoniste triple pour récepteurs glp-1, gcg et gip
CA3223313A1 (fr) 2021-06-23 2022-12-29 Eli Lilly And Company Methodes d'utilisation et compositions comprenant un analogue d'incretine
AU2022392980B2 (en) * 2021-11-19 2025-12-18 Jiangsu Deyuan Pharmaceutical Co., Ltd. Stapled peptide and use thereof
CN116162147B (zh) * 2021-11-24 2023-10-03 成都奥达生物科技有限公司 一种长效胰岛素类似物
AU2023348864A1 (en) * 2022-09-28 2025-03-20 Sunshine Lake Pharma Co., Ltd. Glp-1/gcg/gip triple-receptor agonist and use thereof
JP2026502943A (ja) 2022-12-30 2026-01-27 アルギファルマ エーエス 経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法
US20240270821A1 (en) 2023-01-31 2024-08-15 Eli Lilly And Company Gip/glp1/gcg tri-receptor agonists and uses thereof
WO2024213022A1 (fr) * 2023-04-11 2024-10-17 上海多米瑞生物技术有限公司 Analogues d'incrétine et leur procédé de préparation, et utilisation
CN120329412A (zh) * 2023-11-06 2025-07-18 成都奥达生物科技有限公司 一种三激动剂化合物
CN120349393A (zh) * 2023-11-06 2025-07-22 成都奥达生物科技有限公司 一种三激动剂化合物
CN119241684B (zh) * 2024-11-22 2025-02-25 徐州医科大学 一种肠促胰岛素类似物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104127880A (zh) 2009-03-27 2014-11-05 葛兰素集团有限公司 药用融合体和缀合物
AR092873A1 (es) * 2012-09-26 2015-05-06 Cadila Healthcare Ltd Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
WO2015067715A2 (fr) * 2013-11-06 2015-05-14 Zealand Pharma A/S Composés agonistes doubles de gip et glp-1 et procédés associés
CN105829339B (zh) 2013-11-06 2021-03-12 西兰制药公司 胰高血糖素-glp-1-gip三重激动剂化合物
TWI582109B (zh) 2015-01-09 2017-05-11 美國禮來大藥廠 Gip及glp-1共促效劑化合物
WO2016198624A1 (fr) 2015-06-12 2016-12-15 Sanofi Dérivés d'exendine 4 utilisés en tant qu'agonistes trigonaux des récepteurs du glp-1/glucagon/gip
TWI700291B (zh) 2015-06-22 2020-08-01 美國禮來大藥廠 升糖素及glp-1共激動劑化合物
SG11201805586SA (en) 2015-12-31 2018-07-30 Hanmi Pharmaceutical Co Ltd Triple glucagon/glp-1/gip receptor agonist
EP3217027A1 (fr) 2016-03-08 2017-09-13 HILTI Aktiengesellschaft Élement de revetement large destine a entourer une tige d'ancrage
TWI767095B (zh) * 2017-12-21 2022-06-11 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途

Also Published As

Publication number Publication date
MX2025003745A (es) 2025-05-02
IL275469B1 (en) 2026-01-01
JP2022043082A (ja) 2022-03-15
KR102440323B1 (ko) 2022-09-05
AR113487A1 (es) 2020-05-06
NZ765268A (en) 2024-07-05
JOP20200136B1 (ar) 2024-04-18
PH12020551024A1 (en) 2021-05-31
AU2018388895A1 (en) 2020-06-04
KR20200088418A (ko) 2020-07-22
EA202091284A1 (ru) 2020-09-08
DOP2020000124A (es) 2020-08-31
CR20200256A (es) 2020-07-12
SG11202004359YA (en) 2020-06-29
TW202233227A (zh) 2022-09-01
CA3084004A1 (fr) 2019-06-27
BR112020010410A2 (pt) 2020-11-24
US20210221865A1 (en) 2021-07-22
TWI810937B (zh) 2023-08-01
UA127589C2 (uk) 2023-10-25
JP6987993B2 (ja) 2022-01-05
WO2019125929A1 (fr) 2019-06-27
IL325352A (en) 2026-02-01
PE20200926A1 (es) 2020-09-14
IL275469A (en) 2020-08-31
CN111511387A (zh) 2020-08-07
JOP20200136A1 (ar) 2022-10-30
ECSP20032306A (es) 2020-07-31
TWI767095B (zh) 2022-06-11
MY199545A (en) 2023-11-06
CL2020001636A1 (es) 2020-10-16
US11834486B2 (en) 2023-12-05
AU2018388895B2 (en) 2020-12-24
CO2020006253A2 (es) 2020-05-29
JP2021506825A (ja) 2021-02-22
EP3727425A1 (fr) 2020-10-28
US20240190936A1 (en) 2024-06-13
TW201938187A (zh) 2019-10-01
CA3084004C (fr) 2023-06-20
MX2020006547A (es) 2020-12-09

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