MA51305A - Stimulateurs de sgc - Google Patents
Stimulateurs de sgcInfo
- Publication number
- MA51305A MA51305A MA051305A MA51305A MA51305A MA 51305 A MA51305 A MA 51305A MA 051305 A MA051305 A MA 051305A MA 51305 A MA51305 A MA 51305A MA 51305 A MA51305 A MA 51305A
- Authority
- MA
- Morocco
- Prior art keywords
- stimulators
- cms
- cms stimulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762607619P | 2017-12-19 | 2017-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51305A true MA51305A (fr) | 2020-10-28 |
Family
ID=65024070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051305A MA51305A (fr) | 2017-12-19 | 2018-12-19 | Stimulateurs de sgc |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11897887B2 (fr) |
| EP (1) | EP3727388A1 (fr) |
| JP (1) | JP7337067B2 (fr) |
| KR (1) | KR102745228B1 (fr) |
| CN (1) | CN111712247B (fr) |
| AU (1) | AU2018388629B2 (fr) |
| BR (1) | BR112020012629A2 (fr) |
| CA (1) | CA3086207A1 (fr) |
| EA (1) | EA202091502A1 (fr) |
| IL (1) | IL275415B2 (fr) |
| MA (1) | MA51305A (fr) |
| MX (1) | MX2020006433A (fr) |
| PH (1) | PH12020550956A1 (fr) |
| SG (1) | SG11202005718PA (fr) |
| WO (1) | WO2019126354A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| KR20250141845A (ko) | 2018-07-11 | 2025-09-29 | 티센토 쎄라퓨틱스 인크. | 미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도 |
| CN116829158A (zh) * | 2020-11-03 | 2023-09-29 | R发现有限责任公司 | 治疗癌症和吞噬作用缺陷相关疾病的疗法 |
| US20240208979A1 (en) * | 2021-04-20 | 2024-06-27 | Tisento Therapeutics Inc. | sGC STIMULATORS |
| EP4326268A1 (fr) | 2021-04-20 | 2024-02-28 | Tisento Therapeutics Inc. | Traitement de maladies du snc avec des stimulateurs de sgc |
| CN117957228A (zh) * | 2021-04-20 | 2024-04-30 | 帝善多制药公司 | sGC刺激剂 |
| EP4472620A1 (fr) | 2022-02-01 | 2024-12-11 | Charité - Universitätsmedizin Berlin | Activateur de guanylate cyclase soluble pour le traitement d'un dysfonctionnement vasculaire chronique |
| EP4605394A1 (fr) * | 2022-10-18 | 2025-08-27 | Tisento Therapeutics Inc. | Stimulateurs de la sgc pyrimidiques |
| EP4605080A1 (fr) | 2022-10-18 | 2025-08-27 | Tisento Therapeutics Inc. | Traitement de maladies mitochondriales avec stimulateurs de sgc |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2928079B2 (ja) | 1994-02-14 | 1999-07-28 | 永信薬品工業股▲ふん▼有限公司 | １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途 |
| DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| DE19830430A1 (de) | 1998-07-08 | 2000-01-13 | Hoechst Marion Roussel De Gmbh | Schwefelsubstituierte Sulfonylamino-carbonsäure-N-arylamide, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| CZ302691B6 (cs) | 1998-07-08 | 2011-09-07 | Sanofi - Aventis Deutschland GmbH | N-Arylamidová sloucenina, zpusob její prípravy, farmaceutický prostredek tuto slouceninu obsahující, tato sloucenina pro použití jako aktivátor a pro použití k terapii nebo profylaxi |
| DE19834044A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Neue substituierte Pyrazolderivate |
| DE19834047A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituierte Pyrazolderivate |
| GB9824310D0 (en) | 1998-11-05 | 1998-12-30 | Univ London | Activators of soluble guanylate cyclase |
| DE19942809A1 (de) | 1999-09-08 | 2001-03-15 | Bayer Ag | Verfahren zur Herstellung substituierter Pyrimidinderivate |
| DE19943635A1 (de) | 1999-09-13 | 2001-03-15 | Bayer Ag | Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften |
| AUPR237301A0 (en) * | 2001-01-02 | 2001-01-25 | Fujisawa Pharmaceutical Co., Ltd. | Benzhydryl derivatives |
| DE10216145A1 (de) | 2002-04-12 | 2003-10-23 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Glaukom |
| DE10220570A1 (de) * | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamat-substituierte Pyrazolopyridine |
| JP2009507032A (ja) * | 2005-09-02 | 2009-02-19 | アボット・ラボラトリーズ | 新規なイミダゾ系複素環 |
| BRPI0816382A2 (pt) | 2007-09-06 | 2015-02-24 | Merck Sharp & Dohme | Composto, composição, e, métodos para ativar a guanilato ciclase solúvel e para tratar ou previnir doenças |
| WO2009094242A1 (fr) | 2008-01-24 | 2009-07-30 | Merck & Co., Inc. | Antagonistes du récepteur de l'angiotensine ii |
| AU2009322836B2 (en) | 2008-11-25 | 2013-04-04 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| KR20110133034A (ko) | 2009-02-26 | 2011-12-09 | 머크 샤프 앤드 돔 코포레이션 | 가용성 구아닐레이트 시클라제 활성화제 |
| US9284301B2 (en) | 2010-03-25 | 2016-03-15 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| DE102010021637A1 (de) * | 2010-05-26 | 2011-12-01 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung |
| KR20140019004A (ko) | 2010-05-27 | 2014-02-13 | 머크 샤프 앤드 돔 코포레이션 | 가용성 구아닐레이트 시클라제 활성화제 |
| EP2632551B1 (fr) | 2010-10-28 | 2016-07-06 | Merck Sharp & Dohme Corp. | Activateurs de la guanylate cyclase soluble |
| DE102012200356A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte Imidazopyridine und Imidazopyridazine und ihre Verwendung |
| DE102011075399A1 (de) * | 2011-05-06 | 2012-11-08 | Bayer Pharma Aktiengesellschaft | Substituierte Imidazopyridine und Imidazopyridazine und ihre Verwendung |
| DE102011007890A1 (de) | 2011-04-21 | 2012-10-25 | Bayer Pharma Aktiengesellschaft | Fluoralkyl-substituierte Pyrazolopyridine und ihre Verwendung |
| EA033168B1 (ru) * | 2013-03-15 | 2019-09-30 | Сайклерион Терапьютикс, Инк. | СТИМУЛЯТОРЫ sGC |
| CA2933250A1 (fr) * | 2013-12-11 | 2015-06-18 | Ironwood Pharmaceuticals, Inc. | Stimulateurs de la sgc |
| EP3094327A1 (fr) * | 2014-01-13 | 2016-11-23 | Ironwood Pharmaceuticals, Inc. | Utilisation de stimulateurs de la sgc pour le traitement de troubles neuromusculaires |
| US9796733B2 (en) * | 2014-06-04 | 2017-10-24 | Merck Sharp & Dohme Corp. | Imidazo-pyrazine derivatives useful as soluble guanylate cyclase activators |
| EP3194382B1 (fr) * | 2014-09-17 | 2021-09-08 | Cyclerion Therapeutics, Inc. | Dérivés de pyrazole utilisés comme stimulateurs de sgc |
| TW201625635A (zh) * | 2014-11-21 | 2016-07-16 | 默沙東藥廠 | 作為可溶性鳥苷酸環化酶活化劑之三唑并吡基衍生物 |
| WO2016191335A1 (fr) * | 2015-05-28 | 2016-12-01 | Merck Sharp & Dohme Corp. | Dérivés d'imidazo-pyrazinyle utiles à titre d'activateurs de guanylate cyclase solubles |
| WO2017197555A1 (fr) * | 2016-05-16 | 2017-11-23 | Merck Sharp & Dohme Corp. | Dérivés de pyrazine fusionnés utiles en tant que stimulateurs de la guanylate cyclase soluble |
-
2018
- 2018-12-19 MX MX2020006433A patent/MX2020006433A/es unknown
- 2018-12-19 IL IL275415A patent/IL275415B2/en unknown
- 2018-12-19 JP JP2020534495A patent/JP7337067B2/ja active Active
- 2018-12-19 WO PCT/US2018/066547 patent/WO2019126354A1/fr not_active Ceased
- 2018-12-19 KR KR1020207020292A patent/KR102745228B1/ko active Active
- 2018-12-19 AU AU2018388629A patent/AU2018388629B2/en active Active
- 2018-12-19 EA EA202091502A patent/EA202091502A1/ru unknown
- 2018-12-19 CN CN201880089157.2A patent/CN111712247B/zh active Active
- 2018-12-19 CA CA3086207A patent/CA3086207A1/fr active Pending
- 2018-12-19 BR BR112020012629-2A patent/BR112020012629A2/pt active Search and Examination
- 2018-12-19 US US16/955,494 patent/US11897887B2/en active Active
- 2018-12-19 MA MA051305A patent/MA51305A/fr unknown
- 2018-12-19 EP EP18834185.3A patent/EP3727388A1/fr active Pending
- 2018-12-19 SG SG11202005718PA patent/SG11202005718PA/en unknown
-
2020
- 2020-06-19 PH PH12020550956A patent/PH12020550956A1/en unknown
-
2024
- 2024-06-21 US US18/750,080 patent/US20250059197A1/en not_active Abandoned
- 2024-11-08 US US18/941,365 patent/US20250243205A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018388629B2 (en) | 2023-11-16 |
| US20200377508A1 (en) | 2020-12-03 |
| BR112020012629A2 (pt) | 2020-12-01 |
| PH12020550956A1 (en) | 2021-03-22 |
| KR20200100696A (ko) | 2020-08-26 |
| CA3086207A1 (fr) | 2019-06-27 |
| US20250059197A1 (en) | 2025-02-20 |
| JP2021508326A (ja) | 2021-03-04 |
| CN111712247A (zh) | 2020-09-25 |
| KR102745228B1 (ko) | 2024-12-19 |
| EA202091502A1 (ru) | 2020-11-12 |
| WO2019126354A1 (fr) | 2019-06-27 |
| SG11202005718PA (en) | 2020-07-29 |
| MX2020006433A (es) | 2020-09-17 |
| US11897887B2 (en) | 2024-02-13 |
| IL275415B2 (en) | 2026-04-01 |
| IL275415B1 (en) | 2025-12-01 |
| AU2018388629A1 (en) | 2020-07-30 |
| IL275415A (en) | 2020-07-30 |
| US20250243205A1 (en) | 2025-07-31 |
| CN111712247B (zh) | 2024-02-09 |
| JP7337067B2 (ja) | 2023-09-01 |
| EP3727388A1 (fr) | 2020-10-28 |
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