MA51305A - Stimulateurs de sgc - Google Patents
Stimulateurs de sgcInfo
- Publication number
- MA51305A MA51305A MA051305A MA51305A MA51305A MA 51305 A MA51305 A MA 51305A MA 051305 A MA051305 A MA 051305A MA 51305 A MA51305 A MA 51305A MA 51305 A MA51305 A MA 51305A
- Authority
- MA
- Morocco
- Prior art keywords
- stimulators
- cms
- cms stimulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762607619P | 2017-12-19 | 2017-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51305A true MA51305A (fr) | 2020-10-28 |
Family
ID=65024070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051305A MA51305A (fr) | 2017-12-19 | 2018-12-19 | Stimulateurs de sgc |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11897887B2 (fr) |
| EP (1) | EP3727388A1 (fr) |
| JP (1) | JP7337067B2 (fr) |
| KR (1) | KR102745228B1 (fr) |
| CN (1) | CN111712247B (fr) |
| AU (1) | AU2018388629B2 (fr) |
| BR (1) | BR112020012629A2 (fr) |
| CA (1) | CA3086207A1 (fr) |
| EA (1) | EA202091502A1 (fr) |
| IL (1) | IL275415B1 (fr) |
| MA (1) | MA51305A (fr) |
| MX (1) | MX2020006433A (fr) |
| PH (1) | PH12020550956A1 (fr) |
| SG (1) | SG11202005718PA (fr) |
| WO (1) | WO2019126354A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3481818B1 (fr) * | 2016-07-07 | 2023-09-06 | Cyclerion Therapeutics, Inc. | Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble |
| SG11202100092QA (en) | 2018-07-11 | 2021-02-25 | Cyclerion Therapeutics Inc | USE OF sGC STIMULATORS FOR THE TREATMENT OF MITOCHONRIAL DISORDERS |
| CN116829158A (zh) * | 2020-11-03 | 2023-09-29 | R发现有限责任公司 | 治疗癌症和吞噬作用缺陷相关疾病的疗法 |
| AU2022261862A1 (en) | 2021-04-20 | 2023-11-30 | Tisento Therapeutics Inc. | Sgc stimulators |
| TW202308634A (zh) * | 2021-04-20 | 2023-03-01 | 美商賽克瑞恩醫療公司 | 使用sGC刺激劑之CNS疾病治療 |
| CN117957228A (zh) * | 2021-04-20 | 2024-04-30 | 帝善多制药公司 | sGC刺激剂 |
| WO2023148203A1 (fr) | 2022-02-01 | 2023-08-10 | Charité - Universitätsmedizin Berlin | Activateur de guanylate cyclase soluble pour le traitement d'un dysfonctionnement vasculaire chronique |
| EP4605080A1 (fr) | 2022-10-18 | 2025-08-27 | Tisento Therapeutics Inc. | Traitement de maladies mitochondriales avec stimulateurs de sgc |
| JP2025536343A (ja) * | 2022-10-18 | 2025-11-05 | ティセント セラピューティクス インコーポレーテッド | ピリミジンｓｇｃ刺激剤 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2928079B2 (ja) | 1994-02-14 | 1999-07-28 | 永信薬品工業股▲ふん▼有限公司 | １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途 |
| DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| PL199236B1 (pl) | 1998-07-08 | 2008-08-29 | Sanofi Aventis Deutschland | N-Aryloamidy kwasów sulfonyloaminokarboksylowych podstawionych siarką, sposób ich wytwarzania, środek farmaceutyczny i zastosowanie N-aryloamidów kwasów sulfonyloaminokarboksylowych podstawionych siarką |
| DE19830430A1 (de) | 1998-07-08 | 2000-01-13 | Hoechst Marion Roussel De Gmbh | Schwefelsubstituierte Sulfonylamino-carbonsäure-N-arylamide, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE19834047A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituierte Pyrazolderivate |
| DE19834044A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Neue substituierte Pyrazolderivate |
| GB9824310D0 (en) | 1998-11-05 | 1998-12-30 | Univ London | Activators of soluble guanylate cyclase |
| DE19942809A1 (de) | 1999-09-08 | 2001-03-15 | Bayer Ag | Verfahren zur Herstellung substituierter Pyrimidinderivate |
| DE19943635A1 (de) | 1999-09-13 | 2001-03-15 | Bayer Ag | Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften |
| AUPR237301A0 (en) * | 2001-01-02 | 2001-01-25 | Fujisawa Pharmaceutical Co., Ltd. | Benzhydryl derivatives |
| DE10216145A1 (de) | 2002-04-12 | 2003-10-23 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Glaukom |
| DE10220570A1 (de) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamat-substituierte Pyrazolopyridine |
| US7709468B2 (en) * | 2005-09-02 | 2010-05-04 | Abbott Laboratories | Imidazo based heterocycles |
| CN101939053A (zh) | 2007-09-06 | 2011-01-05 | 默沙东公司 | 可溶性的鸟苷酸环化酶活化剂 |
| WO2009094242A1 (fr) | 2008-01-24 | 2009-07-30 | Merck & Co., Inc. | Antagonistes du récepteur de l'angiotensine ii |
| WO2010065275A1 (fr) | 2008-11-25 | 2010-06-10 | Merck Sharp & Dohme Corp. | Activateurs de guanylate cyclase soluble |
| EP2401265B1 (fr) | 2009-02-26 | 2016-09-14 | Merck Sharp & Dohme Corp. | Derives d'acide 1-pyri(mid)in-2-yl-pyrazole-4-carboxylique utiles dans la therapie ou la prophylaxie de maladies cardiovasculaires |
| EP2549875B1 (fr) | 2010-03-25 | 2015-05-13 | Merck Sharp & Dohme Corp. | Activateurs de guanylate cyclase solubles |
| DE102010021637A1 (de) * | 2010-05-26 | 2011-12-01 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung |
| EP2575473B1 (fr) | 2010-05-27 | 2016-01-20 | Merck Sharp & Dohme Corp. | Activateurs de guanylate cyclase soluble |
| EP2632551B1 (fr) | 2010-10-28 | 2016-07-06 | Merck Sharp & Dohme Corp. | Activateurs de la guanylate cyclase soluble |
| DE102011075399A1 (de) * | 2011-05-06 | 2012-11-08 | Bayer Pharma Aktiengesellschaft | Substituierte Imidazopyridine und Imidazopyridazine und ihre Verwendung |
| DE102012200356A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte Imidazopyridine und Imidazopyridazine und ihre Verwendung |
| DE102011007890A1 (de) | 2011-04-21 | 2012-10-25 | Bayer Pharma Aktiengesellschaft | Fluoralkyl-substituierte Pyrazolopyridine und ihre Verwendung |
| RS63108B1 (sr) | 2013-03-15 | 2022-04-29 | Cyclerion Therapeutics Inc | Sgc stimulatori |
| US20160311826A1 (en) * | 2013-12-11 | 2016-10-27 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP3094327A1 (fr) * | 2014-01-13 | 2016-11-23 | Ironwood Pharmaceuticals, Inc. | Utilisation de stimulateurs de la sgc pour le traitement de troubles neuromusculaires |
| EP3152214B1 (fr) | 2014-06-04 | 2020-01-29 | Merck Sharp & Dohme Corp. | Dérivés d'imidazo-pyrazine utiles en tant qu'activateurs de guanylate cyclases solubles |
| US20170291889A1 (en) * | 2014-09-17 | 2017-10-12 | Ironwood Pharmaceuticals, Inc. | Pyrazole derivatives as sgc stimulators |
| TW201625635A (zh) * | 2014-11-21 | 2016-07-16 | 默沙東藥廠 | 作為可溶性鳥苷酸環化酶活化劑之三唑并吡基衍生物 |
| WO2016191335A1 (fr) * | 2015-05-28 | 2016-12-01 | Merck Sharp & Dohme Corp. | Dérivés d'imidazo-pyrazinyle utiles à titre d'activateurs de guanylate cyclase solubles |
| WO2017197555A1 (fr) * | 2016-05-16 | 2017-11-23 | Merck Sharp & Dohme Corp. | Dérivés de pyrazine fusionnés utiles en tant que stimulateurs de la guanylate cyclase soluble |
-
2018
- 2018-12-19 MA MA051305A patent/MA51305A/fr unknown
- 2018-12-19 KR KR1020207020292A patent/KR102745228B1/ko active Active
- 2018-12-19 SG SG11202005718PA patent/SG11202005718PA/en unknown
- 2018-12-19 BR BR112020012629-2A patent/BR112020012629A2/pt active Search and Examination
- 2018-12-19 WO PCT/US2018/066547 patent/WO2019126354A1/fr not_active Ceased
- 2018-12-19 AU AU2018388629A patent/AU2018388629B2/en active Active
- 2018-12-19 MX MX2020006433A patent/MX2020006433A/es unknown
- 2018-12-19 CN CN201880089157.2A patent/CN111712247B/zh active Active
- 2018-12-19 EP EP18834185.3A patent/EP3727388A1/fr active Pending
- 2018-12-19 JP JP2020534495A patent/JP7337067B2/ja active Active
- 2018-12-19 US US16/955,494 patent/US11897887B2/en active Active
- 2018-12-19 CA CA3086207A patent/CA3086207A1/fr active Pending
- 2018-12-19 EA EA202091502A patent/EA202091502A1/ru unknown
-
2020
- 2020-06-15 IL IL275415A patent/IL275415B1/en unknown
- 2020-06-19 PH PH12020550956A patent/PH12020550956A1/en unknown
-
2024
- 2024-06-21 US US18/750,080 patent/US20250059197A1/en not_active Abandoned
- 2024-11-08 US US18/941,365 patent/US20250243205A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019126354A1 (fr) | 2019-06-27 |
| US20200377508A1 (en) | 2020-12-03 |
| KR20200100696A (ko) | 2020-08-26 |
| US20250243205A1 (en) | 2025-07-31 |
| SG11202005718PA (en) | 2020-07-29 |
| CN111712247B (zh) | 2024-02-09 |
| IL275415B1 (en) | 2025-12-01 |
| US20250059197A1 (en) | 2025-02-20 |
| KR102745228B1 (ko) | 2024-12-19 |
| AU2018388629B2 (en) | 2023-11-16 |
| CN111712247A (zh) | 2020-09-25 |
| BR112020012629A2 (pt) | 2020-12-01 |
| EP3727388A1 (fr) | 2020-10-28 |
| CA3086207A1 (fr) | 2019-06-27 |
| IL275415A (en) | 2020-07-30 |
| EA202091502A1 (ru) | 2020-11-12 |
| JP2021508326A (ja) | 2021-03-04 |
| MX2020006433A (es) | 2020-09-17 |
| JP7337067B2 (ja) | 2023-09-01 |
| PH12020550956A1 (en) | 2021-03-22 |
| US11897887B2 (en) | 2024-02-13 |
| AU2018388629A1 (en) | 2020-07-30 |
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