MA51899A - Inhibiteurs de btk et de leurs mutants - Google Patents
Inhibiteurs de btk et de leurs mutantsInfo
- Publication number
- MA51899A MA51899A MA051899A MA51899A MA51899A MA 51899 A MA51899 A MA 51899A MA 051899 A MA051899 A MA 051899A MA 51899 A MA51899 A MA 51899A MA 51899 A MA51899 A MA 51899A
- Authority
- MA
- Morocco
- Prior art keywords
- btk
- mutants
- inhibitors
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q20/00—Payment architectures, schemes or protocols
- G06Q20/30—Payment architectures, schemes or protocols characterised by the use of specific devices or networks
- G06Q20/34—Payment architectures, schemes or protocols characterised by the use of specific devices or networks using cards, e.g. integrated circuit [IC] cards or magnetic cards
- G06Q20/349—Rechargeable cards
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
- G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
- G06K19/067—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components
- G06K19/07—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components with integrated circuit chips
- G06K19/0723—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components with integrated circuit chips the record carrier comprising an arrangement for non-contact communication, e.g. wireless communication circuits on transponder cards, non-contact smart cards or RFIDs
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q20/00—Payment architectures, schemes or protocols
- G06Q20/30—Payment architectures, schemes or protocols characterised by the use of specific devices or networks
- G06Q20/34—Payment architectures, schemes or protocols characterised by the use of specific devices or networks using cards, e.g. integrated circuit [IC] cards or magnetic cards
- G06Q20/341—Active cards, i.e. cards including their own processing means, e.g. including an IC or chip
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Business, Economics & Management (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Theoretical Computer Science (AREA)
- Physics & Mathematics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Microelectronics & Electronic Packaging (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Strategic Management (AREA)
- Accounting & Taxation (AREA)
- General Business, Economics & Management (AREA)
- Computer Hardware Design (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862631945P | 2018-02-19 | 2018-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51899A true MA51899A (fr) | 2020-12-30 |
Family
ID=65685969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051899A MA51899A (fr) | 2018-02-19 | 2019-02-15 | Inhibiteurs de btk et de leurs mutants |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11501284B2 (fr) |
| EP (1) | EP3755702A1 (fr) |
| JP (1) | JP7535949B2 (fr) |
| KR (1) | KR102861971B1 (fr) |
| CN (2) | CN111741959B (fr) |
| AU (1) | AU2019222475B2 (fr) |
| CA (1) | CA3088796A1 (fr) |
| IL (1) | IL276575B2 (fr) |
| MA (1) | MA51899A (fr) |
| MX (1) | MX2020008627A (fr) |
| SG (1) | SG11202006274XA (fr) |
| WO (1) | WO2019161152A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020008627A (es) * | 2018-02-19 | 2020-09-21 | Guangzhou Lupeng Pharmaceutical Company Ltd | Inhibidores de btk y mutantes de los mismos. |
| EP3930717A1 (fr) * | 2019-02-25 | 2022-01-05 | Guangzhou Lupeng Pharmaceutical Company Ltd. | Inhibiteurs de btk et leurs mutants |
| WO2021038540A1 (fr) | 2019-08-31 | 2021-03-04 | Sun Pharma Advanced Research Company Limited | Acides cycloalkylidènecarboxyliques et dérivés en tant qu'inhibiteurs de la btk |
| WO2021066958A1 (fr) * | 2019-10-05 | 2021-04-08 | Newave Pharmaceutical Inc. | Inhibiteurs de btk et leurs mutants |
| WO2021164735A1 (fr) | 2020-02-20 | 2021-08-26 | Hutchison Medipharma Limited | Composés hétérocycliques hétéroaryles et leurs utilisations |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| MX2023001865A (es) | 2020-08-14 | 2023-05-09 | Guangzhou Lupeng Pharmaceutical Company Ltd | Composiciones de forma de dosificación que comprenden un inhibidor de btk y mutantes de este. |
| EP4214206A4 (fr) | 2020-09-21 | 2024-10-09 | Hutchison Medipharma Limited | Composés hétérocycliques hétéroaryle et leurs utilisations |
| US20240058457A1 (en) * | 2020-12-20 | 2024-02-22 | Newave Pharmaceutical Inc. | Btk degrader |
| CN117897388A (zh) * | 2020-12-20 | 2024-04-16 | 广州麓鹏制药有限公司 | Btk蛋白降解剂 |
| CN115960124B (zh) * | 2023-02-23 | 2025-02-18 | 康化(上海)新药研发有限公司 | 一种2-氟-3-甲酰基-吡啶-4-硼酸频哪醇酯的合成方法 |
| AU2024320769A1 (en) | 2023-08-07 | 2026-03-05 | Guangzhou Lupeng Pharmaceutical Co., Ltd. | Crystal form vi of acrylamide compound, and preparation method therefor and use thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| SG10201508035TA (en) | 2007-03-28 | 2015-10-29 | Pharmacyclics Inc | Inhibitors of bruton's tyrosine kinase |
| SG10201510696RA (en) | 2008-06-27 | 2016-01-28 | Celgene Avilomics Res Inc | Heteroaryl compounds and uses thereof |
| CN110818724B (zh) * | 2010-05-07 | 2020-11-13 | 吉利德康涅狄格有限公司 | 吡啶酮和氮杂吡啶酮化合物及使用方法 |
| UA111756C2 (uk) * | 2011-11-03 | 2016-06-10 | Ф. Хоффманн-Ля Рош Аг | Сполуки гетероарилпіридону та азапіридону як інгібітори тирозинкінази брутона |
| HK1218416A1 (zh) | 2013-03-05 | 2017-02-17 | F. Hoffmann-La Roche Ag | 布鲁顿氏酪氨酸激酶抑制剂 |
| MX355943B (es) | 2013-06-26 | 2018-05-07 | Abbvie Inc | Carboxamidas primarias como inhibidores de btk. |
| WO2015050703A1 (fr) * | 2013-10-04 | 2015-04-09 | Yi Chen | Inhibiteurs de la tyrosine kinase de bruton |
| EP3077384B1 (fr) * | 2013-12-05 | 2017-09-06 | F. Hoffmann-La Roche AG | Composés de pyridone hétéroarylique et d'aza-pyridone à fonctionnalité électrophile |
| AU2017376580B2 (en) * | 2016-12-15 | 2020-08-13 | F. Hoffmann-La Roche Ag | Process for preparing BTK inhibitors |
| JP2021512059A (ja) | 2018-01-29 | 2021-05-13 | ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド | ブルトン型チロシンキナーゼ(btk)阻害剤のe3リガーゼリガンドとのコンジュゲーションによるbtkの分解および使用方法 |
| MX2020008627A (es) * | 2018-02-19 | 2020-09-21 | Guangzhou Lupeng Pharmaceutical Company Ltd | Inhibidores de btk y mutantes de los mismos. |
| EP3930717A1 (fr) | 2019-02-25 | 2022-01-05 | Guangzhou Lupeng Pharmaceutical Company Ltd. | Inhibiteurs de btk et leurs mutants |
| WO2021066958A1 (fr) | 2019-10-05 | 2021-04-08 | Newave Pharmaceutical Inc. | Inhibiteurs de btk et leurs mutants |
| US20230024442A1 (en) | 2019-11-08 | 2023-01-26 | Nurix Therapeutics, Inc. | Bifunctional compounds for grading btk via ubiquitin proteosome pathway |
-
2019
- 2019-02-15 MX MX2020008627A patent/MX2020008627A/es unknown
- 2019-02-15 KR KR1020207026689A patent/KR102861971B1/ko active Active
- 2019-02-15 JP JP2020566200A patent/JP7535949B2/ja active Active
- 2019-02-15 IL IL276575A patent/IL276575B2/en unknown
- 2019-02-15 SG SG11202006274XA patent/SG11202006274XA/en unknown
- 2019-02-15 AU AU2019222475A patent/AU2019222475B2/en active Active
- 2019-02-15 WO PCT/US2019/018139 patent/WO2019161152A1/fr not_active Ceased
- 2019-02-15 CA CA3088796A patent/CA3088796A1/fr active Pending
- 2019-02-15 MA MA051899A patent/MA51899A/fr unknown
- 2019-02-15 EP EP19709178.8A patent/EP3755702A1/fr active Pending
- 2019-02-15 CN CN201980013997.5A patent/CN111741959B/zh active Active
- 2019-02-15 CN CN202311008387.0A patent/CN117209502A/zh active Pending
-
2020
- 2020-08-18 US US16/996,516 patent/US11501284B2/en active Active
-
2022
- 2022-10-10 US US17/962,798 patent/US12086788B2/en active Active
-
2024
- 2024-08-08 US US18/798,308 patent/US20250045728A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2020008627A (es) | 2020-09-21 |
| US12086788B2 (en) | 2024-09-10 |
| IL276575A (en) | 2020-09-30 |
| KR102861971B1 (ko) | 2025-09-19 |
| WO2019161152A1 (fr) | 2019-08-22 |
| JP2021514390A (ja) | 2021-06-10 |
| US20200377478A1 (en) | 2020-12-03 |
| AU2019222475A1 (en) | 2020-07-30 |
| SG11202006274XA (en) | 2020-07-29 |
| EP3755702A1 (fr) | 2020-12-30 |
| IL276575B2 (en) | 2024-05-01 |
| KR20200122348A (ko) | 2020-10-27 |
| US20250045728A1 (en) | 2025-02-06 |
| IL276575B1 (en) | 2024-01-01 |
| JP7535949B2 (ja) | 2024-08-19 |
| CN117209502A (zh) | 2023-12-12 |
| US20230140433A1 (en) | 2023-05-04 |
| CN111741959A (zh) | 2020-10-02 |
| US11501284B2 (en) | 2022-11-15 |
| CN111741959B (zh) | 2023-09-05 |
| AU2019222475B2 (en) | 2024-08-15 |
| CA3088796A1 (fr) | 2019-08-22 |
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