MA52348A - Composés hétéroaromatiques ayant une activité contre vrs - Google Patents
Composés hétéroaromatiques ayant une activité contre vrsInfo
- Publication number
- MA52348A MA52348A MA052348A MA52348A MA52348A MA 52348 A MA52348 A MA 52348A MA 052348 A MA052348 A MA 052348A MA 52348 A MA52348 A MA 52348A MA 52348 A MA52348 A MA 52348A
- Authority
- MA
- Morocco
- Prior art keywords
- activity against
- heteroaromatic compounds
- against rsv
- rsv
- heteroaromatic
- Prior art date
Links
- 150000002390 heteroarenes Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18168671 | 2018-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA52348A true MA52348A (fr) | 2021-03-03 |
Family
ID=62046706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA052348A MA52348A (fr) | 2018-04-23 | 2019-04-19 | Composés hétéroaromatiques ayant une activité contre vrs |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11708369B2 (fr) |
| EP (1) | EP3784667B1 (fr) |
| JP (1) | JP2021522222A (fr) |
| KR (1) | KR20210005569A (fr) |
| CN (1) | CN112004815A (fr) |
| AU (1) | AU2019260109B2 (fr) |
| CA (1) | CA3095277A1 (fr) |
| EA (1) | EA202092439A1 (fr) |
| ES (1) | ES2957316T3 (fr) |
| MA (1) | MA52348A (fr) |
| MX (1) | MX2020011200A (fr) |
| SG (1) | SG11202010323QA (fr) |
| WO (1) | WO2019206828A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3087926A1 (fr) | 2018-01-31 | 2019-08-08 | Janssen Sciences Ireland Unlimited Company | Pyrazolopyrimidines substituees par cycloalkyle ayant une activite contre le vrs |
| AU2019260109B2 (en) * | 2018-04-23 | 2023-07-13 | Janssen Sciences Ireland Unlimited Company | Heteroaromatic compounds having activity against RSV |
| BR112022024071A2 (pt) | 2020-05-27 | 2022-12-20 | Axial Therapeutics Inc | Compostos moduladores de tlr2, composições farmacêuticas e usos dos mesmos |
| TWI839652B (zh) | 2020-10-28 | 2024-04-21 | 日商鹽野義製藥股份有限公司 | 具有抗病毒活性的醯胺衍生物 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175259A (zh) | 1994-12-22 | 1998-03-04 | 生化制药有限公司 | 低分子量双环凝血酶抑制剂 |
| WO1997001275A1 (fr) | 1995-06-29 | 1997-01-16 | Merck & Co., Inc. | Combinaisons d'inhibiteurs de farnesyl-proteine transferase |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| US5972966A (en) | 1996-12-05 | 1999-10-26 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US5977134A (en) | 1996-12-05 | 1999-11-02 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US6177443B1 (en) | 1997-03-07 | 2001-01-23 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use |
| KR20020063837A (ko) | 1999-07-19 | 2002-08-05 | 시오노기세이야쿠가부시키가이샤 | 아실옥시메톡시카르보닐 측쇄를 갖는 삼환 화합물 |
| EP1113007A1 (fr) | 1999-12-24 | 2001-07-04 | Pfizer Inc. | Composés de tétrahydroisoquinoline comme agonistes/antagonistes d'oestrogène |
| WO2003016274A2 (fr) | 2001-08-21 | 2003-02-27 | Sepracor, Inc. | Piperidines 2-substitue, ligands pour des recepteurs et des transporteurs de monoamines |
| CA2483306A1 (fr) | 2002-04-23 | 2003-11-06 | Shionogi & Co., Ltd. | Derive de pyrazolo[1,5-a]pyrimidine et inhibiteur de la nad(p)h oxydase contenant ledit derive |
| EP1560573B1 (fr) | 2002-09-20 | 2008-12-03 | Medisyn Technologies, Inc. | Utilisation de membres de la famille de n,n-dicylcohexyl-2-hydroxy-7,7-dimethylbicyclo[2.2.1]hept-1-ylmethanesulphonamide en thérapie |
| EP1546132A1 (fr) | 2002-09-26 | 2005-06-29 | Pfizer Limited | Derives de pyrazole utilises en tant qu'inhibiteurs de la transcriptase inverse |
| WO2004037817A1 (fr) | 2002-10-25 | 2004-05-06 | Mitsubishi Pharma Corporation | Composes de n-oxyde |
| TW200505902A (en) | 2003-03-20 | 2005-02-16 | Schering Corp | Cannabinoid receptor ligands |
| WO2004087153A2 (fr) | 2003-03-28 | 2004-10-14 | Chiron Corporation | Utilisation de petites molecules de composes pour une immunopotentialisation |
| FR2856596B1 (fr) | 2003-06-27 | 2007-04-27 | Bioprojet Soc Civ | Nouvelle association medicamenteuse psychiatrique et utilisation d'une antagoniste ou agoniste inverse du recepteur h3 de l'histamine pour preparer un medicament prevenant des effets indesirables de psychotropes. |
| EP1671962A1 (fr) | 2003-10-10 | 2006-06-21 | Ono Pharmaceutical Co., Ltd. | Nouveau compose heterocyclique fondu et utilisation correspondante |
| WO2005042530A1 (fr) | 2003-10-30 | 2005-05-12 | Boehringer Ingelheim (Canada) Ltd. | Inhibiteurs polymerase rsv |
| AR046959A1 (es) | 2003-12-18 | 2006-01-04 | Tibotec Pharm Ltd | Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio |
| CA2551178C (fr) | 2003-12-24 | 2012-11-06 | Biota Scientific Management Pty Ltd | Agents polycycliques pour le traitement d'infections par le virus syncytial respiratoire |
| AU2005283326B2 (en) | 2004-09-13 | 2011-07-21 | Ono Pharmaceutical Co., Ltd. | Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient |
| EP2316458A1 (fr) | 2004-09-20 | 2011-05-04 | Xenon Pharmaceuticals Inc. | Derives de pyridazine destines a l'inhibition du desaturase-coa-stearoyl de l'humain |
| WO2007044085A2 (fr) | 2005-05-19 | 2007-04-19 | Xenon Pharmaceuticals Inc. | Composes heteroaryle et leurs utilisations en tant qu'agents therapeutiques |
| AU2006260969B2 (en) | 2005-06-20 | 2011-11-17 | Janssen Sciences Ireland Uc | 1- ( 2-amino-3- (substituted alkyl)-3H-benzimidazolylmethyl) -3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus |
| US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
| CN101360736A (zh) | 2005-11-23 | 2009-02-04 | 阿斯利康(瑞典)有限公司 | L-丙氨酸衍生物 |
| US20080176870A1 (en) | 2006-11-20 | 2008-07-24 | Bert Nolte | Heterobicyclic metalloprotease inhibitors |
| CN101842098A (zh) | 2007-08-10 | 2010-09-22 | 基因实验室技术有限公司 | 用于治疗病毒感染的含氮的二环化学实体 |
| MX2010006243A (es) | 2007-12-06 | 2010-08-31 | Schering Corp | Moduladores de gamma secretasa. |
| AR073739A1 (es) | 2008-09-10 | 2010-12-01 | Kalypsys Inc | Aminopirimidinas como inhibidores de los receptores de histamina |
| CA2738453C (fr) | 2008-10-23 | 2017-07-04 | Boehringer Ingelheim International Gmbh | Derivees d'uree de nortropanes substitues, medicaments contenant de tels composes et leur utilisation |
| US20100204265A1 (en) | 2009-02-09 | 2010-08-12 | Genelabs Technologies, Inc. | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections |
| WO2010104306A2 (fr) | 2009-03-07 | 2010-09-16 | 주식회사 메디젠텍 | Compositions pharmaceutiques pour traiter ou prévenir des maladies causées par la translocation de gsk3 du noyau cellulaire au cytoplasme, contenant des composés inhibant la translocation de gsk3 du noyau cellulaire au cytoplasme |
| WO2010111058A1 (fr) | 2009-03-23 | 2010-09-30 | Merck Sharp & Dohme Corp. | Antagonistes du récepteur p2x3 pour le traitement de la douleur |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| EP2853531A3 (fr) | 2009-06-11 | 2015-08-12 | AbbVie Bahamas Ltd. | Composés antiviraux |
| CN102958933B (zh) | 2010-06-24 | 2016-02-03 | 吉里德科学公司 | 作为抗病毒药的吡唑并[1,5-a]嘧啶类 |
| ES2647486T3 (es) | 2011-12-22 | 2017-12-21 | Gilead Sciences, Inc. | Pirazolo[1,5-a]pirimidinas como agentes antivirales |
| EA027855B1 (ru) | 2012-04-17 | 2017-09-29 | Гайлид Сайэнсиз, Инк. | Соединения и способы для противовирусной терапии |
| CA2924527C (fr) | 2013-09-20 | 2022-07-12 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Composes destines au traitement du cancer de la prostate |
| JP6510539B2 (ja) | 2014-01-09 | 2019-05-08 | ザ ジェイ. デヴィッド グラッドストーン インスティテューツ, ア テスタメンタリー トラスト エスタブリッシュド アンダー ザ ウィル オブ ジェイ. デヴィッド グラッドストーン | 置換ベンゾオキサジン及び関連化合物 |
| KR101551313B1 (ko) | 2014-07-28 | 2015-09-09 | 충남대학교산학협력단 | 신규한 인덴 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 망막 질환의 예방 또는 치료용 약학적 조성물 |
| CN107108556B (zh) | 2014-11-03 | 2020-09-29 | 艾欧米制药有限公司 | 药用化合物 |
| AU2015359624B2 (en) | 2014-12-08 | 2020-01-02 | Janssen Sciences Ireland Uc | Piperidine substituted pyrazolo[1,5-a]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV) |
| CN105777632A (zh) | 2015-01-09 | 2016-07-20 | 成都贝斯凯瑞生物科技有限公司 | 芳环并氮杂环衍生物及其应用 |
| JO3637B1 (ar) | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv |
| TW201932470A (zh) | 2017-11-29 | 2019-08-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 具有抗rsv活性之吡唑并嘧啶 |
| CA3087926A1 (fr) | 2018-01-31 | 2019-08-08 | Janssen Sciences Ireland Unlimited Company | Pyrazolopyrimidines substituees par cycloalkyle ayant une activite contre le vrs |
| AU2019260109B2 (en) * | 2018-04-23 | 2023-07-13 | Janssen Sciences Ireland Unlimited Company | Heteroaromatic compounds having activity against RSV |
| US20220033396A1 (en) | 2018-11-26 | 2022-02-03 | Janssen Sciences Ireland Unlimited Company | Further heteroaromatic compounds having activity against rsv |
| US20240158390A1 (en) | 2019-05-23 | 2024-05-16 | Janssen Sciences Ireland Unlimited Company | Other heteroaromatic compounds having activity against rsv |
-
2019
- 2019-04-19 AU AU2019260109A patent/AU2019260109B2/en not_active Ceased
- 2019-04-19 EA EA202092439A patent/EA202092439A1/ru unknown
- 2019-04-19 ES ES19718707T patent/ES2957316T3/es active Active
- 2019-04-19 MX MX2020011200A patent/MX2020011200A/es unknown
- 2019-04-19 US US17/050,419 patent/US11708369B2/en active Active
- 2019-04-19 EP EP19718707.3A patent/EP3784667B1/fr active Active
- 2019-04-19 SG SG11202010323QA patent/SG11202010323QA/en unknown
- 2019-04-19 WO PCT/EP2019/060216 patent/WO2019206828A1/fr not_active Ceased
- 2019-04-19 CN CN201980027482.0A patent/CN112004815A/zh active Pending
- 2019-04-19 JP JP2020558603A patent/JP2021522222A/ja active Pending
- 2019-04-19 KR KR1020207029130A patent/KR20210005569A/ko not_active Ceased
- 2019-04-19 CA CA3095277A patent/CA3095277A1/fr active Pending
- 2019-04-19 MA MA052348A patent/MA52348A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3784667B1 (fr) | 2023-08-16 |
| JP2021522222A (ja) | 2021-08-30 |
| MX2020011200A (es) | 2020-11-13 |
| EP3784667C0 (fr) | 2023-08-16 |
| WO2019206828A1 (fr) | 2019-10-31 |
| EP3784667A1 (fr) | 2021-03-03 |
| EA202092439A1 (ru) | 2021-03-05 |
| SG11202010323QA (en) | 2020-11-27 |
| CN112004815A (zh) | 2020-11-27 |
| US11708369B2 (en) | 2023-07-25 |
| ES2957316T3 (es) | 2024-01-17 |
| AU2019260109A1 (en) | 2020-09-17 |
| KR20210005569A (ko) | 2021-01-14 |
| CA3095277A1 (fr) | 2019-10-31 |
| US20210094958A1 (en) | 2021-04-01 |
| AU2019260109B2 (en) | 2023-07-13 |
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