MA52954A - Procédé pour la fabrication d'aminoéthers de diaryle et sels de chlorhydrate d'aminoéthers de diaryle - Google Patents
Procédé pour la fabrication d'aminoéthers de diaryle et sels de chlorhydrate d'aminoéthers de diaryleInfo
- Publication number
- MA52954A MA52954A MA052954A MA52954A MA52954A MA 52954 A MA52954 A MA 52954A MA 052954 A MA052954 A MA 052954A MA 52954 A MA52954 A MA 52954A MA 52954 A MA52954 A MA 52954A
- Authority
- MA
- Morocco
- Prior art keywords
- aminoethers
- diaryl
- manufacture
- hydrochloride salts
- hydrochloride
- Prior art date
Links
- YCWSUKQGVSGXJO-NTUHNPAUSA-N nifuroxazide Chemical compound C1=CC(O)=CC=C1C(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 YCWSUKQGVSGXJO-NTUHNPAUSA-N 0.000 title 2
- 150000003840 hydrochlorides Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18179034 | 2018-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA52954A true MA52954A (fr) | 2021-04-28 |
Family
ID=62873133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA052954A MA52954A (fr) | 2018-06-21 | 2019-06-20 | Procédé pour la fabrication d'aminoéthers de diaryle et sels de chlorhydrate d'aminoéthers de diaryle |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11472771B2 (fr) |
| EP (1) | EP3810574A1 (fr) |
| JP (2) | JP2021528444A (fr) |
| CN (2) | CN119019324A (fr) |
| AU (1) | AU2019289917B2 (fr) |
| BR (2) | BR122023023452A2 (fr) |
| CA (1) | CA3102129A1 (fr) |
| EA (1) | EA202190024A1 (fr) |
| IL (1) | IL279476B2 (fr) |
| MA (1) | MA52954A (fr) |
| MX (1) | MX2020014129A (fr) |
| PH (1) | PH12020552038A1 (fr) |
| SA (1) | SA520420837B1 (fr) |
| SG (1) | SG11202011932SA (fr) |
| TW (1) | TWI853819B (fr) |
| UA (1) | UA128888C2 (fr) |
| WO (1) | WO2019243523A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA52954A (fr) * | 2018-06-21 | 2021-04-28 | Cellestia Biotech Ag | Procédé pour la fabrication d'aminoéthers de diaryle et sels de chlorhydrate d'aminoéthers de diaryle |
| WO2022058418A1 (fr) * | 2020-09-16 | 2022-03-24 | Cellestia Biotech Ag | Nouvelle utilisation d'inhibiteurs de la voie de signalisation notch |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8430252D0 (en) | 1984-11-30 | 1985-01-09 | Beecham Group Plc | Compounds |
| US4816373A (en) | 1986-01-31 | 1989-03-28 | Mitsubishi Paper Mills, Ltd. | Method of producing images |
| AU4633893A (en) | 1992-06-17 | 1994-01-04 | University Of Massachusetts Medical Center | Liposomal formulations for administering to cancer patients |
| GB9312891D0 (en) | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| US5935924A (en) | 1994-04-15 | 1999-08-10 | Genentech, Inc. | Treatment of congestive heart failure |
| EP0889033B1 (fr) | 1995-09-29 | 2003-01-08 | Shionogi & Co., Ltd. | Derives heterocycliques de benzyle substitue en alpha, intermediaires servant a leur fabrication, et pesticides dont ils forment le principe actif |
| US6214966B1 (en) | 1996-09-26 | 2001-04-10 | Shearwater Corporation | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution |
| TR199902301T2 (xx) | 1997-03-19 | 1999-12-21 | Basf Aktiengesellschaft | Pirilo $2,3D]pirimidinler ve onlar�n kullan�m�. |
| US6692919B1 (en) | 1997-07-23 | 2004-02-17 | Yale University | Activated forms of notch and methods based thereon |
| EP1049664B1 (fr) * | 1997-12-22 | 2005-03-16 | Bayer Pharmaceuticals Corporation | Inhibition de raf kinase au moyen de diphenylurees substituees symetriques et asymetriques |
| US20080269265A1 (en) * | 1998-12-22 | 2008-10-30 | Scott Miller | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas |
| EP1140840B1 (fr) | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | Diphenylurees a substituants -g(v)-carboxyaryles, inhibitrices de kinase raf |
| KR100642955B1 (ko) | 1999-04-23 | 2006-11-10 | 알자 코포레이션 | 방출성 결합 및 그를 함유하는 조성물 |
| GB9910577D0 (en) * | 1999-05-08 | 1999-07-07 | Zeneca Ltd | Chemical compounds |
| JP2001089412A (ja) | 1999-09-22 | 2001-04-03 | Otsuka Pharmaceut Co Ltd | ベンゼン誘導体またはその医薬的に許容される塩 |
| WO2002046161A1 (fr) * | 2000-12-05 | 2002-06-13 | Kyorin Pharmaceutical Co., Ltd. | Derives de l'acide carboxylique substitues |
| DE60221866T2 (de) | 2001-10-19 | 2008-05-29 | Ortho-Mcneil Pharmaceutical, Inc. | 2-PHENYL BENZIMIDAZOLE UND IMIDAZO-i4,5ö-PYRIDINE ALS CDS1/CHK2-INHIBITOREN UND ADJUVANTIEN IN DER CHEMOTHERAPIE ODER STRAHLUNGSTHERAPIE ZUR BEHANDLUNG VON KREBS |
| EP1461313B1 (fr) | 2001-12-14 | 2009-08-05 | Exelixis, Inc. | Inhibiteurs de l'adam-10 humaine |
| AU2003255735A1 (en) | 2002-08-03 | 2004-02-23 | Lorantis Limited | Conjugate of notch signalling pathway modulators and their use in medical treatment |
| US20050214250A1 (en) | 2003-11-06 | 2005-09-29 | Harris J M | Method of preparing carboxylic acid functionalized polymers |
| AU2005272619A1 (en) | 2004-08-13 | 2006-02-23 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (SIP) receptor activity |
| CN101094829B (zh) * | 2004-12-07 | 2012-02-08 | 富山化学工业株式会社 | 新的氨茴酸衍生物或其盐 |
| WO2006118749A1 (fr) | 2005-05-04 | 2006-11-09 | Janssen Pharmaceutica, N.V. | Inhibiteurs de la thia-tetraazaacenaphtylene kinase |
| GB0518232D0 (en) | 2005-09-07 | 2005-10-19 | Merck Sharp & Dohme | New methods |
| EP1894915A1 (fr) * | 2006-09-04 | 2008-03-05 | Bayer Schering Pharma Aktiengesellschaft | Dérivés de phényloxyaniline |
| CL2007003590A1 (es) | 2006-12-12 | 2008-02-29 | Wyeth Corp | Compuestos derivados de aril sulfamida; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en prevencion y tratamiento de sintomas vasomotrices, disfuncion sexual, transtornos gastrointestinales, transt |
| AR068072A1 (es) | 2007-04-19 | 2009-11-04 | Novartis Ag | Derivados de bencimidazoles, composiciones farmaceuticas y usos |
| PE20090321A1 (es) | 2007-06-04 | 2009-04-20 | Genentech Inc | Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica |
| GB0722055D0 (en) | 2007-11-09 | 2007-12-19 | Argenta Discovery Ltd | Compounds |
| JP2011523655A (ja) | 2008-06-03 | 2011-08-18 | フレセニウス メディカル ケア ドイッチュランド ゲーエムベーハー | ガンマセクレターゼモジュレータを含む医薬組成物 |
| WO2010033655A1 (fr) | 2008-09-19 | 2010-03-25 | Complegen, Inc. | Composés et méthodes d’inhibition de la pkc thêta |
| US20100292193A1 (en) | 2009-04-10 | 2010-11-18 | The Regents Of The University Of California | Radioprotective drugs |
| RU2013138835A (ru) * | 2011-02-09 | 2015-03-20 | Ф. Хоффманн-Ля Рош Аг | Гетероциклические соединения в качестве ингибиторов pi3 киназы |
| JPWO2013035827A1 (ja) | 2011-09-09 | 2015-03-23 | 塩野義製薬株式会社 | 新規オレフィン誘導体 |
| EP2606884A1 (fr) | 2011-12-21 | 2013-06-26 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Inhibiteurs de la voie de signalisation notch et leur utilisation dans le traitement des cancers |
| CN103242237A (zh) * | 2013-05-10 | 2013-08-14 | 常州亚邦齐晖医药化工有限公司 | 一种驱虫药芬苯达唑的制备新方法 |
| MA52954A (fr) * | 2018-06-21 | 2021-04-28 | Cellestia Biotech Ag | Procédé pour la fabrication d'aminoéthers de diaryle et sels de chlorhydrate d'aminoéthers de diaryle |
| JP2022528705A (ja) * | 2019-04-10 | 2022-06-15 | セレスティア バイオテック アーゲー | オンコウイルス誘発性がんの治療のための化合物及びその使用方法 |
-
2019
- 2019-06-20 MA MA052954A patent/MA52954A/fr unknown
- 2019-06-20 CN CN202411134795.5A patent/CN119019324A/zh active Pending
- 2019-06-20 JP JP2020571676A patent/JP2021528444A/ja active Pending
- 2019-06-20 US US17/254,166 patent/US11472771B2/en active Active
- 2019-06-20 MX MX2020014129A patent/MX2020014129A/es unknown
- 2019-06-20 WO PCT/EP2019/066381 patent/WO2019243523A1/fr not_active Ceased
- 2019-06-20 BR BR122023023452-9A patent/BR122023023452A2/pt unknown
- 2019-06-20 AU AU2019289917A patent/AU2019289917B2/en active Active
- 2019-06-20 EP EP19737475.4A patent/EP3810574A1/fr active Pending
- 2019-06-20 EA EA202190024A patent/EA202190024A1/ru unknown
- 2019-06-20 CA CA3102129A patent/CA3102129A1/fr active Pending
- 2019-06-20 BR BR112020026148-3A patent/BR112020026148A2/pt active Search and Examination
- 2019-06-20 SG SG11202011932SA patent/SG11202011932SA/en unknown
- 2019-06-20 UA UAA202100147A patent/UA128888C2/uk unknown
- 2019-06-20 TW TW108121506A patent/TWI853819B/zh active
- 2019-06-20 IL IL279476A patent/IL279476B2/en unknown
- 2019-06-20 CN CN201980041500.0A patent/CN112351969A/zh active Pending
-
2020
- 2020-11-27 PH PH12020552038A patent/PH12020552038A1/en unknown
- 2020-12-20 SA SA520420837A patent/SA520420837B1/ar unknown
-
2022
- 2022-08-05 US US17/882,432 patent/US12030855B2/en active Active
-
2024
- 2024-04-04 JP JP2024060993A patent/JP2024099551A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR112020026148A2 (pt) | 2021-03-16 |
| SG11202011932SA (en) | 2021-01-28 |
| US20240254084A9 (en) | 2024-08-01 |
| CA3102129A1 (fr) | 2019-12-26 |
| IL279476B2 (en) | 2024-04-01 |
| EP3810574A1 (fr) | 2021-04-28 |
| CN112351969A (zh) | 2021-02-09 |
| US20220388961A1 (en) | 2022-12-08 |
| IL279476A (en) | 2021-01-31 |
| AU2019289917A1 (en) | 2021-01-07 |
| US12030855B2 (en) | 2024-07-09 |
| JP2021528444A (ja) | 2021-10-21 |
| JP2024099551A (ja) | 2024-07-25 |
| CN119019324A (zh) | 2024-11-26 |
| TW202010737A (zh) | 2020-03-16 |
| KR20210034587A (ko) | 2021-03-30 |
| BR122023023452A2 (pt) | 2024-02-20 |
| AU2019289917B2 (en) | 2025-01-09 |
| IL279476B1 (en) | 2023-12-01 |
| PH12020552038A1 (en) | 2021-08-02 |
| TWI853819B (zh) | 2024-09-01 |
| UA128888C2 (uk) | 2024-11-20 |
| US11472771B2 (en) | 2022-10-18 |
| SA520420837B1 (ar) | 2023-12-05 |
| EA202190024A1 (ru) | 2021-05-19 |
| US20210323921A1 (en) | 2021-10-21 |
| WO2019243523A1 (fr) | 2019-12-26 |
| MX2020014129A (es) | 2021-06-18 |
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