MA54515A - Dérivés de quinoléine destinés à être utilisés dans le traitement de maladies inflammatoires - Google Patents
Dérivés de quinoléine destinés à être utilisés dans le traitement de maladies inflammatoiresInfo
- Publication number
- MA54515A MA54515A MA054515A MA54515A MA54515A MA 54515 A MA54515 A MA 54515A MA 054515 A MA054515 A MA 054515A MA 54515 A MA54515 A MA 54515A MA 54515 A MA54515 A MA 54515A
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- inflammatory diseases
- quinoline derivatives
- quinoline
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/062—Organo-phosphoranes without P-C bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18306782.6A EP3669873A1 (fr) | 2018-12-20 | 2018-12-20 | Dérivés de quinoline destinés à être utilisés dans le traitement de maladies inflammatoires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA54515A true MA54515A (fr) | 2021-10-27 |
Family
ID=65200517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA054515A MA54515A (fr) | 2018-12-20 | 2019-12-19 | Dérivés de quinoléine destinés à être utilisés dans le traitement de maladies inflammatoires |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11992499B2 (fr) |
| EP (2) | EP3669873A1 (fr) |
| JP (2) | JP7678477B2 (fr) |
| KR (1) | KR102844332B1 (fr) |
| CN (3) | CN119950536A (fr) |
| AU (1) | AU2019410432B2 (fr) |
| BR (1) | BR112021012100A2 (fr) |
| CA (1) | CA3122900A1 (fr) |
| IL (2) | IL317817A (fr) |
| MA (1) | MA54515A (fr) |
| MX (2) | MX2021007114A (fr) |
| WO (1) | WO2020127843A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2974729A1 (fr) * | 2014-07-17 | 2016-01-20 | Abivax | Dérivés de quinoléine utilisés dans le traitement de maladies inflammatoires |
| EP4301374A4 (fr) | 2021-03-01 | 2025-09-10 | Deciduous Therapeutics Inc | Composés pour activer des lymphocytes t tueurs naturels invariants et méthodes d'utilisation dans l'élimination de cellules sénescentes inflammatoires |
| WO2022247920A1 (fr) | 2021-05-27 | 2022-12-01 | 江苏恒瑞医药股份有限公司 | Composé quinolinamine, son procédé de préparation et son utilisation dans des produits pharmaceutiques |
| EP4201948A1 (fr) | 2021-12-21 | 2023-06-28 | Abivax | Procédé de préparation de dérivés d'acide 1-(n-(quinoléine-2-yl)-(phénylamino)-1-désoxy-bêta-d-glucopyranuronique |
| EP4212156A1 (fr) * | 2022-01-13 | 2023-07-19 | Abivax | Combinaison de 8-chloro-n-(4-(trifluorométhoxy)phényl)quinolin-2-amine et de ses dérivés avec un modulateur de récepteur de s1p |
| TW202333698A (zh) * | 2022-01-24 | 2023-09-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 喹啉胺類化合物、其製備方法及其在醫藥上的應用 |
| EP4215196A1 (fr) * | 2022-01-24 | 2023-07-26 | Abivax | Combinaison de 8-chloro-n-(4-(trifluorométhoxy)phényl)quinolin-2-amine et de ses dérivés avec un inhibiteur de jak |
| TW202436295A (zh) * | 2022-11-25 | 2024-09-16 | 大陸商江蘇恒瑞醫藥股份有限公司 | 喹啉胺類化合物的可藥用鹽、晶型及其製備方法 |
| TW202436296A (zh) | 2022-11-25 | 2024-09-16 | 大陸商江蘇恒瑞醫藥股份有限公司 | 喹啉胺類化合物晶型及其製備方法 |
| CN118373771A (zh) * | 2023-01-20 | 2024-07-23 | 江苏柯菲平医药股份有限公司 | 一种喹啉衍生化合物或其可药用的盐及其制备方法和应用 |
| AU2024282281B2 (en) * | 2023-06-02 | 2026-06-25 | Westol, Llc | 2,8-dihydroxyquinoline glucuronide derivatives with enhanced properties for use as anticancer, antiviral, antimicrobial, and other therapeutic applications |
| WO2025201294A1 (fr) * | 2024-03-26 | 2025-10-02 | 深圳信立泰药业股份有限公司 | Composé indole, son procédé de préparation et son utilisation dans la régulation positive de mir |
| EP4785940A1 (fr) * | 2025-01-31 | 2026-08-05 | Abivax | Combinaison d'obefazimod et de ses dérivés avec un inhibiteur de tnf alpha |
| EP4785941A1 (fr) | 2025-01-31 | 2026-08-05 | Abivax | Combinaison d'obefazimod et de ses dérivés avec une anti-intégrine alpha4bêta7 |
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| JP2012520891A (ja) | 2009-03-19 | 2012-09-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | スルホニルキノリンの製造方法 |
| WO2010127208A1 (fr) | 2009-04-30 | 2010-11-04 | Forest Laboratories Holdings Limited | Inhibiteurs de l'acétyl-coa carboxylase |
| US8633320B2 (en) | 2009-05-05 | 2014-01-21 | Boehringer Ingelheim International Gmbh | Process for preparing bromo-substituted quinolines |
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| EP2266972A1 (fr) | 2009-06-12 | 2010-12-29 | Splicos | Nouvelles molécules chimiques qui inhibent le mécanisme d'épissage pour le traitement de maladies résultant d'anomalies d'épissage |
| HRP20191460T1 (hr) | 2009-06-12 | 2019-11-15 | Abivax | Spojevi korisni za liječenje raka |
| US10253020B2 (en) | 2009-06-12 | 2019-04-09 | Abivax | Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging |
| CN102625804B (zh) | 2009-06-12 | 2015-04-08 | Abivax公司 | 用于治疗aids的化合物 |
| WO2010151755A2 (fr) | 2009-06-25 | 2010-12-29 | The Brigham And Women's Hospital, Inc. | Traitement de maladies inflammatoires à l'aide du microarn mir-124 |
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| ES2622138T3 (es) | 2010-06-23 | 2017-07-05 | Hanmi Science Co., Ltd. | Nuevos derivados de pirimidina condensados para la inhibición de la actividad tirosina quinasa |
| EP2465502A1 (fr) | 2010-12-15 | 2012-06-20 | Société Splicos | Composés utiles pour traiter le SIDA |
| US20140051085A1 (en) | 2011-03-01 | 2014-02-20 | The Scripps Research Institute | Direct reprogramming of human fibroblasts to functional neurons under defined conditions |
| WO2013039394A1 (fr) | 2011-09-15 | 2013-03-21 | Self-Screen B.V. | Analyse de méthylation d'échantillons autonomes en tant qu'outil de triage pour des femmes positives pour hpv |
| US20150272959A1 (en) | 2012-10-04 | 2015-10-01 | Oyagen, Inc. | Small molecules as anti-hiv agents that disrupt vif self-association and methods of use thereof |
| EP2757161A1 (fr) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 comme biomarqueur de l'infection virale |
| CA2916623C (fr) | 2013-07-05 | 2021-09-14 | Abivax | Composes bicycliques utiles pour le traitement de maladies causees par des retrovirus |
| WO2015131019A1 (fr) | 2014-02-28 | 2015-09-03 | The Texas A&M University System | Compositions et méthodes d'inhibition de mycobactéries |
| EP2975034A1 (fr) | 2014-07-17 | 2016-01-20 | Abivax | Dérivé de quinoléine pour le traitement de maladies inflammatoires et du sida |
| EP2974729A1 (fr) | 2014-07-17 | 2016-01-20 | Abivax | Dérivés de quinoléine utilisés dans le traitement de maladies inflammatoires |
| EP3059236A1 (fr) | 2015-02-23 | 2016-08-24 | Abivax | Nouveau dérivé de quinoléine pour utilisation dans le traitement et la prévention d'infections virales |
| EP3058940A1 (fr) * | 2015-02-23 | 2016-08-24 | Abivax | Dérivés de quinoline utilisés dans le traitement ou la prévention d'une infection virale |
| WO2017158201A1 (fr) | 2016-03-18 | 2017-09-21 | Ratiopharm Gmbh | Procédé de préparation de dérivés de quinoléin-2-yl-phénylamine et leurs sels |
-
2018
- 2018-12-20 EP EP18306782.6A patent/EP3669873A1/fr not_active Withdrawn
-
2019
- 2019-12-19 MX MX2021007114A patent/MX2021007114A/es unknown
- 2019-12-19 US US17/416,856 patent/US11992499B2/en active Active
- 2019-12-19 IL IL317817A patent/IL317817A/en unknown
- 2019-12-19 CN CN202510072717.5A patent/CN119950536A/zh active Pending
- 2019-12-19 IL IL284125A patent/IL284125B2/en unknown
- 2019-12-19 WO PCT/EP2019/086477 patent/WO2020127843A1/fr not_active Ceased
- 2019-12-19 CN CN202511811792.5A patent/CN121846117A/zh active Pending
- 2019-12-19 EP EP19829571.9A patent/EP3897640A1/fr active Pending
- 2019-12-19 MA MA054515A patent/MA54515A/fr unknown
- 2019-12-19 JP JP2021535248A patent/JP7678477B2/ja active Active
- 2019-12-19 KR KR1020217022677A patent/KR102844332B1/ko active Active
- 2019-12-19 CN CN201980088825.4A patent/CN113825509A/zh active Pending
- 2019-12-19 BR BR112021012100-5A patent/BR112021012100A2/pt unknown
- 2019-12-19 CA CA3122900A patent/CA3122900A1/fr active Pending
- 2019-12-19 AU AU2019410432A patent/AU2019410432B2/en active Active
-
2021
- 2021-06-15 MX MX2024015470A patent/MX2024015470A/es unknown
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2024
- 2024-04-10 JP JP2024063468A patent/JP2024095786A/ja active Pending
- 2024-04-15 US US18/635,542 patent/US20250275994A1/en active Pending
- 2024-04-15 US US18/635,693 patent/US20260137709A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN119950536A (zh) | 2025-05-09 |
| MX2021007114A (es) | 2021-08-11 |
| KR102844332B1 (ko) | 2025-08-08 |
| US20220023324A1 (en) | 2022-01-27 |
| CA3122900A1 (fr) | 2020-06-25 |
| JP2022513516A (ja) | 2022-02-08 |
| IL317817A (en) | 2025-02-01 |
| US20260137709A1 (en) | 2026-05-21 |
| IL284125B1 (en) | 2025-05-01 |
| IL284125B2 (en) | 2025-09-01 |
| IL284125A (en) | 2021-08-31 |
| US20250275994A1 (en) | 2025-09-04 |
| WO2020127843A1 (fr) | 2020-06-25 |
| EP3669873A1 (fr) | 2020-06-24 |
| JP2024095786A (ja) | 2024-07-10 |
| MX2024015470A (es) | 2025-02-10 |
| US11992499B2 (en) | 2024-05-28 |
| KR20210136970A (ko) | 2021-11-17 |
| AU2019410432A1 (en) | 2021-07-15 |
| AU2019410432B2 (en) | 2025-06-26 |
| JP7678477B2 (ja) | 2025-05-16 |
| CN113825509A (zh) | 2021-12-21 |
| EP3897640A1 (fr) | 2021-10-27 |
| BR112021012100A2 (pt) | 2021-09-08 |
| CN121846117A (zh) | 2026-04-14 |
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