MA56129A - Procédés de production d'un anticorps anti-alpha4béta7 - Google Patents

Procédés de production d'un anticorps anti-alpha4béta7

Info

Publication number
MA56129A
MA56129A MA056129A MA56129A MA56129A MA 56129 A MA56129 A MA 56129A MA 056129 A MA056129 A MA 056129A MA 56129 A MA56129 A MA 56129A MA 56129 A MA56129 A MA 56129A
Authority
MA
Morocco
Prior art keywords
antibody
producing
methods
Prior art date
Application number
MA056129A
Other languages
English (en)
Inventor
Debra Ameli
Paras Bhatia
Susan R Carter
Michael E Dolan
Nicole Hilo
Amitava Kundu
Amy Miller
Olga Paley
George Parks
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MA56129A publication Critical patent/MA56129A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA056129A 2019-06-10 2020-06-10 Procédés de production d'un anticorps anti-alpha4béta7 MA56129A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962859494P 2019-06-10 2019-06-10

Publications (1)

Publication Number Publication Date
MA56129A true MA56129A (fr) 2022-04-13

Family

ID=73781728

Family Applications (1)

Application Number Title Priority Date Filing Date
MA056129A MA56129A (fr) 2019-06-10 2020-06-10 Procédés de production d'un anticorps anti-alpha4béta7

Country Status (14)

Country Link
US (1) US20220267449A1 (fr)
EP (1) EP3980466A4 (fr)
JP (2) JP7624414B2 (fr)
CN (3) CN121736106A (fr)
AR (1) AR119270A1 (fr)
AU (1) AU2020290943A1 (fr)
BR (1) BR112021024897A2 (fr)
CA (1) CA3143167A1 (fr)
IL (1) IL288825A (fr)
MA (1) MA56129A (fr)
MX (3) MX2021015300A (fr)
PL (1) PL439809A1 (fr)
TW (1) TW202112818A (fr)
WO (1) WO2020252069A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112292146A (zh) 2018-04-10 2021-01-29 雷迪博士实验室有限公司 治疗性抗体的稳定的制剂
US12024561B2 (en) * 2018-04-10 2024-07-02 Dr. Reddy's Laboratories Limited Stable antibody formulation
TW202112819A (zh) * 2019-06-10 2021-04-01 美商千禧製藥公司 用於抗體製備之細胞培養方法及組合物
US20240376209A1 (en) * 2021-07-29 2024-11-14 Dr. Reddy’S Laboratories Limited Method To Control High Molecular Weight Aggregates In An Antibody Composition
EP4380948A4 (fr) * 2021-08-05 2025-07-16 Dr Reddys Laboratories Ltd Procédé de purification d'une composition d'anticorps au moyen d'une chromatographie par échange de cations
US20240400610A1 (en) * 2021-09-03 2024-12-05 Dr. Reddy's Laboratories Limited Method to obtain a purified antibody composition
WO2024233992A2 (fr) * 2023-05-11 2024-11-14 Trophogen, Inc. Procédés de fabrication d'hormones de glycoprotéine hautement glycosylées et leurs analogues
EP4720125A1 (fr) 2023-05-30 2026-04-08 Paragon Therapeutics, Inc. Compositions d'anticorps anti-intégrine alpha4beta7 et procédés d'utilisation
EP4762093A1 (fr) 2023-08-14 2026-06-24 Paragon Therapeutics, Inc. Protéines de liaison à l'intégrine alpha 4 bêta 7 et procédés d'utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
UA116189C2 (uk) * 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
WO2014142882A1 (fr) * 2013-03-14 2014-09-18 Abbvie Inc. Purification de protéine utilisant une chromatographie de déplacement
EP3116891B1 (fr) * 2014-03-10 2020-02-12 Richter Gedeon Nyrt. Purification d'immunoglobuline à l'aide d'étapes de pré-nettoyage
MA41636A (fr) * 2015-03-06 2018-01-09 Millennium Pharm Inc Méthode de traitement de la cholangite sclérosante primitive

Also Published As

Publication number Publication date
MX2021015300A (es) 2022-02-03
JP2025063035A (ja) 2025-04-15
CN121736106A (zh) 2026-03-27
US20220267449A1 (en) 2022-08-25
TW202112818A (zh) 2021-04-01
MX2026003881A (es) 2026-05-04
EP3980466A4 (fr) 2023-06-07
EP3980466A1 (fr) 2022-04-13
CN114375307B (zh) 2025-12-05
CA3143167A1 (fr) 2020-12-17
MX2026003883A (es) 2026-05-04
AR119270A1 (es) 2021-12-09
JP2022536486A (ja) 2022-08-17
CN114375307A (zh) 2022-04-19
JP7624414B2 (ja) 2025-01-30
JP7877431B2 (ja) 2026-06-22
IL288825A (en) 2022-02-01
AU2020290943A1 (en) 2022-02-03
WO2020252069A1 (fr) 2020-12-17
CN119859188A (zh) 2025-04-22
BR112021024897A2 (pt) 2022-01-18
PL439809A1 (pl) 2022-12-05

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