MD4123C1 - Способ получения селенита железа Fe2Se3O9∙6H2O и способ культивирования цианобактерии Spirulina platensis с его использованием - Google Patents
Способ получения селенита железа Fe2Se3O9∙6H2O и способ культивирования цианобактерии Spirulina platensis с его использованием Download PDFInfo
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- iron
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- selenite
- selenium
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- 238000000034 method Methods 0.000 title claims abstract description 33
- 240000002900 Arthrospira platensis Species 0.000 title claims abstract description 27
- 235000016425 Arthrospira platensis Nutrition 0.000 title claims abstract description 26
- 230000008569 process Effects 0.000 title claims abstract description 25
- 241001464430 Cyanobacterium Species 0.000 title claims abstract description 11
- LTOIKHSTLLWYAR-UHFFFAOYSA-L iron(2+);selenite Chemical compound [Fe+2].[O-][Se]([O-])=O LTOIKHSTLLWYAR-UHFFFAOYSA-L 0.000 title abstract description 9
- 238000004519 manufacturing process Methods 0.000 title abstract description 4
- 239000002028 Biomass Substances 0.000 claims abstract description 30
- 235000015097 nutrients Nutrition 0.000 claims abstract description 13
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 8
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 claims abstract description 8
- JKQOBWVOAYFWKG-UHFFFAOYSA-N molybdenum trioxide Chemical compound O=[Mo](=O)=O JKQOBWVOAYFWKG-UHFFFAOYSA-N 0.000 claims abstract description 8
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229910000359 iron(II) sulfate Inorganic materials 0.000 claims abstract description 7
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims abstract description 5
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract description 5
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract description 5
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims abstract description 4
- 229910003597 H2SeO3 Inorganic materials 0.000 claims abstract description 4
- 229910021380 Manganese Chloride Inorganic materials 0.000 claims abstract description 4
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 claims abstract description 4
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000001110 calcium chloride Substances 0.000 claims abstract description 4
- 235000011148 calcium chloride Nutrition 0.000 claims abstract description 4
- 229910001628 calcium chloride Inorganic materials 0.000 claims abstract description 4
- 229910052927 chalcanthite Inorganic materials 0.000 claims abstract description 4
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims abstract description 4
- 235000019797 dipotassium phosphate Nutrition 0.000 claims abstract description 4
- 229910000396 dipotassium phosphate Inorganic materials 0.000 claims abstract description 4
- 239000011565 manganese chloride Substances 0.000 claims abstract description 4
- 235000002867 manganese chloride Nutrition 0.000 claims abstract description 4
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 claims abstract description 4
- 229910052939 potassium sulfate Inorganic materials 0.000 claims abstract description 4
- 239000011780 sodium chloride Substances 0.000 claims abstract description 4
- 235000010344 sodium nitrate Nutrition 0.000 claims abstract description 4
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims abstract description 4
- 229910000368 zinc sulfate Inorganic materials 0.000 claims abstract description 4
- 239000011686 zinc sulphate Substances 0.000 claims abstract description 4
- 235000009529 zinc sulphate Nutrition 0.000 claims abstract description 4
- 229910052564 epsomite Inorganic materials 0.000 claims abstract description 3
- 238000002360 preparation method Methods 0.000 claims abstract description 3
- 239000000203 mixture Substances 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- -1 Fe(III) selenite hexahydrate Chemical class 0.000 claims description 13
- 229940082569 selenite Drugs 0.000 claims description 10
- 229910018143 SeO3 Inorganic materials 0.000 claims description 7
- 238000005286 illumination Methods 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims description 4
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 3
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims description 3
- 235000011130 ammonium sulphate Nutrition 0.000 claims description 3
- 238000011081 inoculation Methods 0.000 claims description 3
- 238000004364 calculation method Methods 0.000 claims description 2
- 235000019441 ethanol Nutrition 0.000 claims description 2
- 239000002244 precipitate Substances 0.000 claims description 2
- MCAHWIHFGHIESP-UHFFFAOYSA-L selenite(2-) Chemical compound [O-][Se]([O-])=O MCAHWIHFGHIESP-UHFFFAOYSA-L 0.000 claims description 2
- 239000011573 trace mineral Substances 0.000 claims description 2
- 235000013619 trace mineral Nutrition 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract description 67
- 239000011669 selenium Substances 0.000 abstract description 38
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract description 36
- 229910052711 selenium Inorganic materials 0.000 abstract description 36
- 229910052742 iron Inorganic materials 0.000 abstract description 35
- 239000000243 solution Substances 0.000 abstract description 11
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract description 9
- 235000010755 mineral Nutrition 0.000 abstract description 9
- 239000011707 mineral Substances 0.000 abstract description 9
- 239000000725 suspension Substances 0.000 abstract description 6
- 239000007864 aqueous solution Substances 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract description 2
- 230000003993 interaction Effects 0.000 abstract description 2
- KWCBONPMAFANBV-UHFFFAOYSA-H iron(3+);triselenite Chemical compound [Fe+3].[Fe+3].[O-][Se]([O-])=O.[O-][Se]([O-])=O.[O-][Se]([O-])=O KWCBONPMAFANBV-UHFFFAOYSA-H 0.000 abstract description 2
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 abstract 1
- PIUMSTDPKHKRMM-UHFFFAOYSA-H iron(3+) triselenite hexahydrate Chemical compound [Se](=O)([O-])[O-].[Fe+3].O.O.O.O.O.O.[Se](=O)([O-])[O-].[Se](=O)([O-])[O-].[Fe+3] PIUMSTDPKHKRMM-UHFFFAOYSA-H 0.000 abstract 1
- 229940091258 selenium supplement Drugs 0.000 description 34
- 150000001875 compounds Chemical class 0.000 description 20
- 239000002609 medium Substances 0.000 description 15
- 229940082787 spirulina Drugs 0.000 description 12
- 239000000126 substance Substances 0.000 description 10
- 238000001669 Mossbauer spectrum Methods 0.000 description 8
- 229940125904 compound 1 Drugs 0.000 description 5
- 229940126214 compound 3 Drugs 0.000 description 5
- 238000001914 filtration Methods 0.000 description 5
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 description 4
- 239000005695 Ammonium acetate Substances 0.000 description 4
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 4
- 229910003424 Na2SeO3 Inorganic materials 0.000 description 4
- 238000009825 accumulation Methods 0.000 description 4
- 235000019257 ammonium acetate Nutrition 0.000 description 4
- 229940043376 ammonium acetate Drugs 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 229940125782 compound 2 Drugs 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 description 4
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 235000015921 sodium selenite Nutrition 0.000 description 4
- 239000011781 sodium selenite Substances 0.000 description 4
- 238000002441 X-ray diffraction Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 229910017052 cobalt Inorganic materials 0.000 description 3
- 239000010941 cobalt Substances 0.000 description 3
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000013630 prepared media Substances 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- 238000004813 Moessbauer spectroscopy Methods 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 244000309464 bull Species 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 229910052593 corundum Inorganic materials 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000003834 intracellular effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 102000006587 Glutathione peroxidase Human genes 0.000 description 1
- 108700016172 Glutathione peroxidases Proteins 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010022971 Iron Deficiencies Diseases 0.000 description 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 102000008114 Selenoproteins Human genes 0.000 description 1
- 108010074686 Selenoproteins Proteins 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000011449 brick Substances 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- XLJKHNWPARRRJB-UHFFFAOYSA-N cobalt(2+) Chemical compound [Co+2] XLJKHNWPARRRJB-UHFFFAOYSA-N 0.000 description 1
- PCBLVZLFLJIUEX-UHFFFAOYSA-L cobalt(2+) hydrogen selenite Chemical compound [Se](=O)(O)[O-].[Co+2].[Se](=O)(O)[O-] PCBLVZLFLJIUEX-UHFFFAOYSA-L 0.000 description 1
- 238000010835 comparative analysis Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013256 coordination polymer Substances 0.000 description 1
- 229920001795 coordination polymer Polymers 0.000 description 1
- 239000010431 corundum Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000002447 crystallographic data Methods 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 150000004687 hexahydrates Chemical class 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 229910000358 iron sulfate Inorganic materials 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 229910052961 molybdenite Inorganic materials 0.000 description 1
- CWQXQMHSOZUFJS-UHFFFAOYSA-N molybdenum disulfide Chemical compound S=[Mo]=S CWQXQMHSOZUFJS-UHFFFAOYSA-N 0.000 description 1
- 229910052982 molybdenum disulfide Inorganic materials 0.000 description 1
- 239000002114 nanocomposite Substances 0.000 description 1
- 235000020939 nutritional additive Nutrition 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
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- 230000005855 radiation Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- ZMEDPVUPEWMUSA-UHFFFAOYSA-N selenous acid dihydrate Chemical compound O.O.O[Se](O)=O ZMEDPVUPEWMUSA-UHFFFAOYSA-N 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 229910021646 siderite Inorganic materials 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000002076 thermal analysis method Methods 0.000 description 1
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- 231100000701 toxic element Toxicity 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 229910001845 yogo sapphire Inorganic materials 0.000 description 1
- 229910000859 α-Fe Inorganic materials 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение относится к способу получения селенита железа и его использования при культивированиицианобактерии Spirulina platensis, с повышенным содержанием селена и железа и может бытьприменено в медицине и пищевой промышленности.Предлагается простой способ получения в мягких условиях селенита Fe(III) гексагидрата Fe2Se3O9·6H2O, предусматривающий взаимодействие при 55…65°С водных растворов железа(II) и H2SeO3. Полученный продукт представляет собой микрокристаллическую форму природного минерала мандариноита.Также, заявляется способ культивированияцианобактерии Spirulina platensis, предусматривающий приготовление питательной среды, которая содержит, г/л: NaHCO3 - 2,0, K2HPO4 - 0,5, NaNO3 - 2,5, K2SO4 - 0,5, NaCl - 1,0, MgSO4·7H2O - 0,2, CaCl2 - 0,04, FeSO4 - 0,01, EDTA - 0,08, а также микроэлементы, вводимые в виде отдельного раствора - 1 мл, содержащий в свою очередь (г/л): H3BO3 - 2,86, MnCl2·4H2O - 1,81, ZnSO4·7H2O - 0,22, CuSO4·5H2O - 0,08 и MoO3 - 0,015. Далее проводят инокуляцию указанной цианобактерии в концентрации 0,40…0,45 мг/л и ее культивирование в течение 6 дней при температуре 30±2°С, освещенности 3000 лк и рН 9,5…10,5, потом отделение и сушку полученной биомассы. При этом к питательной среде, в первые три дня культивирования, в качестве источника селена и железа добавляется порционно в виде суспензии упомянутый селенит железа(III) из расчета 0,015…0,030 г/л.Полученный технический результат состоит в увеличении содержания селена и железа в биомассе цианобактерии в 2,0…2,9 и 1,4…2,9 раза.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20110028A MD4123C1 (ru) | 2011-03-24 | 2011-03-24 | Способ получения селенита железа Fe2Se3O9∙6H2O и способ культивирования цианобактерии Spirulina platensis с его использованием |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20110028A MD4123C1 (ru) | 2011-03-24 | 2011-03-24 | Способ получения селенита железа Fe2Se3O9∙6H2O и способ культивирования цианобактерии Spirulina platensis с его использованием |
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| MD4123B1 MD4123B1 (en) | 2011-07-31 |
| MD4123C1 true MD4123C1 (ru) | 2012-02-29 |
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| MDA20110028A MD4123C1 (ru) | 2011-03-24 | 2011-03-24 | Способ получения селенита железа Fe2Se3O9∙6H2O и способ культивирования цианобактерии Spirulina platensis с его использованием |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4543B1 (ru) * | 2017-02-15 | 2017-12-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Способ культивирования цианобактерии Spirulina platensis |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08266856A (ja) * | 1995-03-30 | 1996-10-15 | Mitsubishi Heavy Ind Ltd | 排煙処理システム |
| RU2199582C2 (ru) * | 2000-10-24 | 2003-02-27 | Институт физиологии растений им. К.А.Тимирязева | Способ получения обогащенной селеном биомассы спирулины (spirulina platensis) |
| CN1463914A (zh) * | 2002-06-18 | 2003-12-31 | 中国科学院山西煤炭化学研究所 | 一种结晶硒铁复合物Fe(HSeO3)(Se2O5)的制备方法 |
| US6773680B2 (en) * | 1995-03-30 | 2004-08-10 | Mitsubishi Jukogyo Kabushiki Kaisha | Combustion exhaust gas treatment system |
| MD2386C2 (ru) * | 2001-05-15 | 2004-10-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Способ культивирования цианобактерии Spirulina platensis |
| US6932980B1 (en) * | 2001-01-18 | 2005-08-23 | Richard Sayre | Method of making microalgal-based animal foodstuff supplements, microalgal-supplemented animal foodstuffs and method of animal nutrition |
| MD3101G2 (ru) * | 2005-12-26 | 2007-02-28 | Государственный Университет Молд0 | Способ получения биомассы Spirulina platensis |
| MD3417G2 (ru) * | 2007-03-16 | 2008-05-31 | Государственный Университет Молд0 | Питательная среда для выращивания цианобактерии Spirulina platensis |
| MD3625G2 (ru) * | 2007-07-11 | 2009-01-31 | Государственный Университет Молд0 | Гептаазотат гекса-(m-b-аланин-(О,О'))-m3-оксо-три(аква)трижелеза(III) 3,5-гидрат и способ получения биомассы Spirulina platensis |
| MD221Y (ru) * | 2009-11-18 | 2010-06-30 | Общественное Учреждение "Научно-Практический Институт Биотехнологий В Зоотехники И Ветеринарной Медицине" | Способ получения криорезистентного семенного материала быков |
-
2011
- 2011-03-24 MD MDA20110028A patent/MD4123C1/ru not_active IP Right Cessation
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08266856A (ja) * | 1995-03-30 | 1996-10-15 | Mitsubishi Heavy Ind Ltd | 排煙処理システム |
| US6773680B2 (en) * | 1995-03-30 | 2004-08-10 | Mitsubishi Jukogyo Kabushiki Kaisha | Combustion exhaust gas treatment system |
| RU2199582C2 (ru) * | 2000-10-24 | 2003-02-27 | Институт физиологии растений им. К.А.Тимирязева | Способ получения обогащенной селеном биомассы спирулины (spirulina platensis) |
| US6932980B1 (en) * | 2001-01-18 | 2005-08-23 | Richard Sayre | Method of making microalgal-based animal foodstuff supplements, microalgal-supplemented animal foodstuffs and method of animal nutrition |
| MD2386C2 (ru) * | 2001-05-15 | 2004-10-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Способ культивирования цианобактерии Spirulina platensis |
| CN1463914A (zh) * | 2002-06-18 | 2003-12-31 | 中国科学院山西煤炭化学研究所 | 一种结晶硒铁复合物Fe(HSeO3)(Se2O5)的制备方法 |
| MD3101G2 (ru) * | 2005-12-26 | 2007-02-28 | Государственный Университет Молд0 | Способ получения биомассы Spirulina platensis |
| MD3417G2 (ru) * | 2007-03-16 | 2008-05-31 | Государственный Университет Молд0 | Питательная среда для выращивания цианобактерии Spirulina platensis |
| MD3625G2 (ru) * | 2007-07-11 | 2009-01-31 | Государственный Университет Молд0 | Гептаазотат гекса-(m-b-аланин-(О,О'))-m3-оксо-три(аква)трижелеза(III) 3,5-гидрат и способ получения биомассы Spirulina platensis |
| MD221Y (ru) * | 2009-11-18 | 2010-06-30 | Общественное Учреждение "Научно-Практический Институт Биотехнологий В Зоотехники И Ветеринарной Медицине" | Способ получения криорезистентного семенного материала быков |
Non-Patent Citations (8)
| Title |
|---|
| Dhanpat Rai, Shas V. Mattigod and Dean A. Moore // Mat. Res. Bull., Vol. 23, pp. 1621-1628, 1988 * |
| Frank C. Hawthorne // Canadian Mineralogist. Vol. 22, pp. 475-480 (1984) * |
| Gerald Giester,Franz Pertik and Franz Braudstatter, Material Rersearch Bulletin, 1996, vol. 31, issue 10, pp. 1189-1193. * |
| P.S. Thund and J.S. Gandhi. Polyhedron, 1986, vol.5, issue 10. pp.1629-1634. * |
| Pete J. Dunn, Donald R. Peacor, B. Darko Sturman // Canadian Mineralogist. Vol.16, pp. 605-609 (1978) * |
| Pritam Singh Thind and Jatinder Singh Gandhi. Bull.Chem.Soc.Japan, 1987, vol. 60, Nr. 3, pp.1129-1130. * |
| Rudic V. Aspecte noi ale biotehnologiei moderne. Chişinău, Ştiinţa, 1993, p. 72-74 * |
| Wolfgang Kaim, Brigitte Schwederski "Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life." John Wiley and Sons, 1994 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4543B1 (ru) * | 2017-02-15 | 2017-12-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Способ культивирования цианобактерии Spirulina platensis |
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| MD4123B1 (en) | 2011-07-31 |
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