MD4202B1 - Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles] - Google Patents

Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles] Download PDF

Info

Publication number
MD4202B1
MD4202B1 MD20120031A MD20120031A MD4202B1 MD 4202 B1 MD4202 B1 MD 4202B1 MD 20120031 A MD20120031 A MD 20120031A MD 20120031 A MD20120031 A MD 20120031A MD 4202 B1 MD4202 B1 MD 4202B1
Authority
MD
Moldova
Prior art keywords
oxindoles
cyclopropane
spiro
carbomethoxy
derivatives
Prior art date
Application number
MD20120031A
Other languages
Moldavian (mo)
Romanian (ro)
Other versions
MD4202C1 (en
Inventor
Natalia Sucman
Flyur Makaev
Fliur MACAEV
Original Assignee
Inst De Chimie Al Academiei De Stiinte A Moldovei
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst De Chimie Al Academiei De Stiinte A Moldovei filed Critical Inst De Chimie Al Academiei De Stiinte A Moldovei
Priority to MDA20120031A priority Critical patent/MD4202C1/en
Publication of MD4202B1 publication Critical patent/MD4202B1/en
Publication of MD4202C1 publication Critical patent/MD4202C1/en

Links

Landscapes

  • Indole Compounds (AREA)

Abstract

The invention relates to the synthesis of spiro[cyclopropane-oxindoles] functionalized with the carbomethoxy group, which can serve as precursors in the synthesis of substances with anti-HIV activity.The process involves the reaction of cyclopropanation of diazoisatins with methyl acrylate, used both as reagent and solvent at its boiling point.The proposed process allows of carrying out the reaction in a shorter time with high yields, without the use of catalysts and inert atmosphere.
MDA20120031A 2012-03-21 2012-03-21 Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles] MD4202C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20120031A MD4202C1 (en) 2012-03-21 2012-03-21 Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles]

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20120031A MD4202C1 (en) 2012-03-21 2012-03-21 Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles]

Publications (2)

Publication Number Publication Date
MD4202B1 true MD4202B1 (en) 2013-02-28
MD4202C1 MD4202C1 (en) 2013-09-30

Family

ID=47831223

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20120031A MD4202C1 (en) 2012-03-21 2012-03-21 Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles]

Country Status (1)

Country Link
MD (1) MD4202C1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57102863A (en) * 1980-12-16 1982-06-26 Takeda Chem Ind Ltd Spiroindolinone and its preparation
FR2740136B1 (en) * 1995-10-24 1998-01-09 Sanofi Sa INDOLIN-2-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US7205328B2 (en) * 2002-10-21 2007-04-17 Irm Llc Oxindoles with anti-HIV activity
US7370333B2 (en) * 2003-06-02 2008-05-06 Microsoft Corporation Efficient processing of a convoy workflow scenario in a message driven process
US7309787B2 (en) * 2005-07-13 2007-12-18 Allergan, Inc. Kinase inhibitors

Also Published As

Publication number Publication date
MD4202C1 (en) 2013-09-30

Similar Documents

Publication Publication Date Title
MY164542A (en) Method for the production of acrylic acid or its derivatives
MY168081A (en) Ethyl acetate production
MY164527A (en) Process for production of acrylic acid or its derivatives
IN2012DE00662A (en)
EA201790916A1 (en) NEW RIG-I LIGANDS AND METHODS OF THEIR RECEPTION
WO2013108045A3 (en) Process intensification in the catalytic synthesis of supported catalysts with hierarchic pore structure
WO2012030065A3 (en) Catalyst composition for hydroformylation reaction and a hydroformylation process using the same
MY167171A (en) METHOD FOR PRODUCING p-XYLENE AND/OR p-TOLUALDEHYDE
IN2014DN09600A (en)
WO2013018915A3 (en) Improved process of dehydration reactions
WO2014057498A3 (en) Process for the preparation of cobicistat intermediates
WO2012137152A3 (en) Method for preparing formamide compounds
EA201270706A1 (en) METHODS OF OBTAINING STYRENE AND CATALYSTS FOR USE IN THEM
GB201100531D0 (en) Functionalised materials, processes for the production and uses thereof
IN2014KN02722A (en)
WO2012115402A3 (en) Crystalline form of docetaxel and process for preparation thereof
CA2897927C (en) Process for the conversion of saccharide-containing feedstock
IL238931A0 (en) Process for the preparation of (1s,4s,5s)-4-bromo-6-oxabicyclo[3.2.1]octan-7-one
MD4202B1 (en) Process for production of carbomethoxy derivatives of spiro[cyclopropane-oxindoles]
MX349985B (en) Process for preparing cis-alkoxy-substituted spirocyclic phenylacetylamino acid esters and cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives.
MD4201B1 (en) Process for production of carbonitrile derivatives of spiro[cyclopropane-oxindoles]
WO2013002592A3 (en) Method for purifying high-purity betulonic acid, method for preparing piperazine betulonic acid amide derivative using high-purity betulonic acid and derivative thereof, and method for purifying high-purity boc-lysinated betulonic acid using high-purity betulonic acid
MX2015014835A (en) Catalytic synthesis of reduced furan derivatives.
IN2014DN09850A (en)
WO2012134102A3 (en) Norbornene diester derivatives, method for preparing same, and use thereof

Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees