MD4216C1 - Штамм дрожжей Saccharomyces cerevisiae - продуцент маннанов - Google Patents
Штамм дрожжей Saccharomyces cerevisiae - продуцент маннанов Download PDFInfo
- Publication number
- MD4216C1 MD4216C1 MDA20120063A MD20120063A MD4216C1 MD 4216 C1 MD4216 C1 MD 4216C1 MD A20120063 A MDA20120063 A MD A20120063A MD 20120063 A MD20120063 A MD 20120063A MD 4216 C1 MD4216 C1 MD 4216C1
- Authority
- MD
- Moldova
- Prior art keywords
- mannans
- strain
- yeast
- saccharomyces cerevisiae
- producer
- Prior art date
Links
- 240000004808 Saccharomyces cerevisiae Species 0.000 title claims abstract description 25
- 229920000057 Mannan Polymers 0.000 title claims abstract description 22
- LUEWUZLMQUOBSB-GFVSVBBRSA-N mannan Chemical class O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-GFVSVBBRSA-N 0.000 title abstract description 14
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 22
- 235000013305 food Nutrition 0.000 abstract description 2
- 150000004676 glycans Chemical class 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 244000005700 microbiome Species 0.000 abstract description 2
- 229920001282 polysaccharide Polymers 0.000 abstract description 2
- 239000005017 polysaccharide Substances 0.000 abstract description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 239000002028 Biomass Substances 0.000 description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- 239000006228 supernatant Substances 0.000 description 12
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 10
- 239000002609 medium Substances 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 7
- 235000019441 ethanol Nutrition 0.000 description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- 239000012029 Fehling's reagent Substances 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 229960000583 acetic acid Drugs 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 239000013049 sediment Substances 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 235000011837 pasties Nutrition 0.000 description 3
- 230000019612 pigmentation Effects 0.000 description 3
- 239000007222 ypd medium Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 102100024023 Histone PARylation factor 1 Human genes 0.000 description 2
- 101001047783 Homo sapiens Histone PARylation factor 1 Proteins 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 2
- 235000011130 ammonium sulphate Nutrition 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- 235000013405 beer Nutrition 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 239000012362 glacial acetic acid Substances 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 210000005253 yeast cell Anatomy 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- 239000004254 Ammonium phosphate Substances 0.000 description 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- 241000235035 Debaryomyces Species 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 239000007836 KH2PO4 Substances 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 102100026933 Myelin-associated neurite-outgrowth inhibitor Human genes 0.000 description 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 241000235648 Pichia Species 0.000 description 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 description 1
- 241000235070 Saccharomyces Species 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 description 1
- 108010046334 Urease Proteins 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 229910000148 ammonium phosphate Inorganic materials 0.000 description 1
- 235000019289 ammonium phosphates Nutrition 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 230000034303 cell budding Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229910052564 epsomite Inorganic materials 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Изобретение относится к биотехнологии, в частности к штамму дрожжей Saccharomyces cerevisiae и может быть использовано в технологии производства полисахаридов, в частности маннанов, используемых в винодельческой, фармацевтической, пищевой отраслях.Штамм дрожжей депонирован в Национальной Коллекции Непатогенных Микроорганизмов Института Микробиологии и Биотехнологии АНМ под номером CNMN-Y-18 и может быть использован в качестве источника маннанов.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20120063A MD4216C1 (ru) | 2012-08-15 | 2012-08-15 | Штамм дрожжей Saccharomyces cerevisiae - продуцент маннанов |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20120063A MD4216C1 (ru) | 2012-08-15 | 2012-08-15 | Штамм дрожжей Saccharomyces cerevisiae - продуцент маннанов |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD4216B1 MD4216B1 (en) | 2013-04-30 |
| MD4216C1 true MD4216C1 (ru) | 2013-11-30 |
Family
ID=48227601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20120063A MD4216C1 (ru) | 2012-08-15 | 2012-08-15 | Штамм дрожжей Saccharomyces cerevisiae - продуцент маннанов |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD4216C1 (ru) |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5497692A (en) * | 1978-01-20 | 1979-08-01 | Grelan Pharmaceut Co Ltd | Linear mannan |
| JPS58109423A (ja) * | 1981-12-22 | 1983-06-29 | Grelan Pharmaceut Co Ltd | 抗感染剤 |
| JPS58121216A (ja) * | 1982-01-13 | 1983-07-19 | Grelan Pharmaceut Co Ltd | リン含有マンナン |
| JPH0984529A (ja) * | 1995-09-27 | 1997-03-31 | Kohjin Co Ltd | 微生物由来のマンナンを含む家畜および家禽用飼料 |
| WO2000008201A1 (de) * | 1998-08-07 | 2000-02-17 | Kulicke Werner Michael | Verfahren zur gewinnung hochmolekularer biologisch aktiver immunmodulierender polysaccharide aus hefe saccharomyces cerevisiae |
| WO2006025295A1 (ja) * | 2004-08-30 | 2006-03-09 | Asahi Breweries, Ltd. | マンナンタンパク質を放出する酵母株およびマンナンタンパク質の製造法 |
| JP2006117566A (ja) * | 2004-10-20 | 2006-05-11 | Asahi Breweries Ltd | 糖代謝改善剤 |
| CN101570769A (zh) * | 2008-04-29 | 2009-11-04 | 安琪酵母股份有限公司 | 一种酵母葡聚糖、甘露聚糖及其生产方法 |
| US20100190872A1 (en) * | 2005-05-05 | 2010-07-29 | Sensient Flavors Inc. | Production of beta-glucans and mannans |
| JP2010284085A (ja) * | 2009-06-09 | 2010-12-24 | Oriental Yeast Co Ltd | 免疫賦活能を有する酵母、及び、食品又は飼料 |
| MD4048C1 (ru) * | 2010-02-11 | 2011-01-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Штамм дрожжей Saccharomyces cerevisiae - источник β-глюканов |
| CN102099461A (zh) * | 2007-12-10 | 2011-06-15 | 东方酵母工业株式会社 | 具有免疫增强作用的酵母及食品或饲料 |
| JP2011178794A (ja) * | 2003-08-11 | 2011-09-15 | Lesaffre & Co | 高血糖症の治療もしくは予防、または血糖の安定化に用いられる酵母細胞壁 |
| CN102488100A (zh) * | 2011-12-22 | 2012-06-13 | 山东轻工业学院 | 一种含有复合益生素的饲料添加剂及其制备方法 |
-
2012
- 2012-08-15 MD MDA20120063A patent/MD4216C1/ru not_active IP Right Cessation
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5497692A (en) * | 1978-01-20 | 1979-08-01 | Grelan Pharmaceut Co Ltd | Linear mannan |
| JPS58109423A (ja) * | 1981-12-22 | 1983-06-29 | Grelan Pharmaceut Co Ltd | 抗感染剤 |
| JPS58121216A (ja) * | 1982-01-13 | 1983-07-19 | Grelan Pharmaceut Co Ltd | リン含有マンナン |
| JPH0984529A (ja) * | 1995-09-27 | 1997-03-31 | Kohjin Co Ltd | 微生物由来のマンナンを含む家畜および家禽用飼料 |
| WO2000008201A1 (de) * | 1998-08-07 | 2000-02-17 | Kulicke Werner Michael | Verfahren zur gewinnung hochmolekularer biologisch aktiver immunmodulierender polysaccharide aus hefe saccharomyces cerevisiae |
| JP2011178794A (ja) * | 2003-08-11 | 2011-09-15 | Lesaffre & Co | 高血糖症の治療もしくは予防、または血糖の安定化に用いられる酵母細胞壁 |
| WO2006025295A1 (ja) * | 2004-08-30 | 2006-03-09 | Asahi Breweries, Ltd. | マンナンタンパク質を放出する酵母株およびマンナンタンパク質の製造法 |
| JP2006117566A (ja) * | 2004-10-20 | 2006-05-11 | Asahi Breweries Ltd | 糖代謝改善剤 |
| US20100190872A1 (en) * | 2005-05-05 | 2010-07-29 | Sensient Flavors Inc. | Production of beta-glucans and mannans |
| CN102099461A (zh) * | 2007-12-10 | 2011-06-15 | 东方酵母工业株式会社 | 具有免疫增强作用的酵母及食品或饲料 |
| CN101570769A (zh) * | 2008-04-29 | 2009-11-04 | 安琪酵母股份有限公司 | 一种酵母葡聚糖、甘露聚糖及其生产方法 |
| JP2010284085A (ja) * | 2009-06-09 | 2010-12-24 | Oriental Yeast Co Ltd | 免疫賦活能を有する酵母、及び、食品又は飼料 |
| MD4048C1 (ru) * | 2010-02-11 | 2011-01-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Штамм дрожжей Saccharomyces cerevisiae - источник β-глюканов |
| CN102488100A (zh) * | 2011-12-22 | 2012-06-13 | 山东轻工业学院 | 一种含有复合益生素的饲料添加剂及其制备方法 |
Non-Patent Citations (2)
| Title |
|---|
| B. Aguilar-Uscanga, J.M. Francois. A study of the yeast cell wall composition and structure in respons to growth conditions and mode of cultivation. Letters in Applied Microbiology, 2003, 37, p. 268-274 * |
| Jan Kocourek, Linton E. Ballou. Method for fingerprinting yeast cell wall mannans. Journal of Bacteriology, 1969, vol. 100, nr. 3, p. 1175-1181 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD4216B1 (en) | 2013-04-30 |
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