MX2009003193A - Interruptores moleculares y metodos para su uso. - Google Patents

Interruptores moleculares y metodos para su uso.

Info

Publication number
MX2009003193A
MX2009003193A MX2009003193A MX2009003193A MX2009003193A MX 2009003193 A MX2009003193 A MX 2009003193A MX 2009003193 A MX2009003193 A MX 2009003193A MX 2009003193 A MX2009003193 A MX 2009003193A MX 2009003193 A MX2009003193 A MX 2009003193A
Authority
MX
Mexico
Prior art keywords
methods
compositions
nucleic acid
molecular switches
relates
Prior art date
Application number
MX2009003193A
Other languages
English (en)
Inventor
Alison Velyian Todd
Elisa Mokany
Donald John Birkett
Tram Bich Doan
Roland Reid Christopher
Original Assignee
Johnson & Johnson Res Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Res Pty Ltd filed Critical Johnson & Johnson Res Pty Ltd
Publication of MX2009003193A publication Critical patent/MX2009003193A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/337—Ribozyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/501—Ligase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/125—Sandwich assay format
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/10—Detection mode being characterised by the assay principle
    • C12Q2565/101—Interaction between at least two labels
    • C12Q2565/1015—Interaction between at least two labels labels being on the same oligonucleotide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente invención se refiere a composiciones y métodos que permiten la manipulación de la actividad catalítica de complejos de ácido nucleico de componentes múltiples. Además, la invención proporciona métodos los cuales usan estas composiciones y métodos para crear sensores moleculares, interruptores moleculares y/o moduladores o propagadores de cascadas auto-replicantes autocatalíticas y otros procesos iterativos. Más particularmente, la invención se refiere a composiciones que permiten el auto-montaje de complejos de ácido nucleico multicomponentes activos e inactivos, métodos para elaborar tales composiciones, y métodos para uso.
MX2009003193A 2006-10-06 2007-10-05 Interruptores moleculares y metodos para su uso. MX2009003193A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82845106P 2006-10-06 2006-10-06
PCT/AU2007/001517 WO2008040095A1 (en) 2006-10-06 2007-10-05 Molecular switches and methods for their use

Publications (1)

Publication Number Publication Date
MX2009003193A true MX2009003193A (es) 2009-08-13

Family

ID=39268069

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003193A MX2009003193A (es) 2006-10-06 2007-10-05 Interruptores moleculares y metodos para su uso.

Country Status (14)

Country Link
US (1) US9127311B2 (es)
EP (1) EP2066817B1 (es)
JP (1) JP5688507B2 (es)
KR (1) KR20090098960A (es)
CN (1) CN101600808B (es)
AU (1) AU2007304837B2 (es)
BR (1) BRPI0718137B1 (es)
CA (1) CA2663164C (es)
DK (1) DK2066817T3 (es)
ES (1) ES2520023T3 (es)
IL (1) IL197543A (es)
MX (1) MX2009003193A (es)
WO (1) WO2008040095A1 (es)
ZA (1) ZA200901742B (es)

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ES2520023T3 (es) 2006-10-06 2014-11-11 Speedx Pty Ltd Interruptores moleculares y métodos para su uso
US8962238B2 (en) * 2007-04-05 2015-02-24 SpeedDx Pty Ltd Nucleic acid enzymes and complexes and methods for their use
WO2012034130A2 (en) 2010-09-10 2012-03-15 Qiagen Methods and compositions for nucleic acid detection
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CN105763200B (zh) * 2016-02-05 2018-10-16 大连大学 基于dna链置换的4-10译码器设计方法
CN105954957B (zh) * 2016-05-02 2018-10-23 福建医科大学 基于金纳米团簇固相复合物的nand逻辑门及其构建方法
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KR102239459B1 (ko) * 2019-09-16 2021-04-12 한국화학연구원 산화 그래핀, DNAzyme 및 PNA를 포함하는 온도 센서용 조성물 및 이를 이용한 온도 센싱 방법
CN111926117B (zh) * 2020-08-18 2022-09-13 交弘生物科技(上海)有限公司 SARS-CoV-2病毒核酸等温快速检测试剂盒及检测方法
CN112501260B (zh) * 2020-11-27 2021-06-29 广东省科学院生态环境与土壤研究所 一种双酚a的检测方法、荧光检测试剂盒及其应用
CN112630439A (zh) * 2020-12-11 2021-04-09 郑州轻工业大学 基于纳米金的分裂型适体传感器及其制备方法和应用

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Also Published As

Publication number Publication date
US20100136536A1 (en) 2010-06-03
EP2066817A4 (en) 2011-02-09
AU2007304837B2 (en) 2011-09-29
CN101600808A (zh) 2009-12-09
EP2066817B1 (en) 2014-07-30
ZA200901742B (en) 2010-06-30
CA2663164C (en) 2016-07-12
BRPI0718137A2 (pt) 2013-11-05
DK2066817T3 (da) 2014-10-13
IL197543A0 (en) 2009-12-24
AU2007304837A1 (en) 2008-04-10
EP2066817A1 (en) 2009-06-10
ES2520023T3 (es) 2014-11-11
CA2663164A1 (en) 2008-04-10
JP5688507B2 (ja) 2015-03-25
CN101600808B (zh) 2014-07-09
WO2008040095A1 (en) 2008-04-10
US9127311B2 (en) 2015-09-08
BRPI0718137B1 (pt) 2016-05-10
IL197543A (en) 2016-10-31
JP2010505394A (ja) 2010-02-25
KR20090098960A (ko) 2009-09-18

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