MX2009009552A - Inhibidores de metaloproteasa que contienen una porcion heterociclica. - Google Patents

Inhibidores de metaloproteasa que contienen una porcion heterociclica.

Info

Publication number
MX2009009552A
MX2009009552A MX2009009552A MX2009009552A MX2009009552A MX 2009009552 A MX2009009552 A MX 2009009552A MX 2009009552 A MX2009009552 A MX 2009009552A MX 2009009552 A MX2009009552 A MX 2009009552A MX 2009009552 A MX2009009552 A MX 2009009552A
Authority
MX
Mexico
Prior art keywords
heterocyclic
heterocyclic moiety
metalloprotease inhibitors
inhibitors containing
moiety
Prior art date
Application number
MX2009009552A
Other languages
English (en)
Inventor
Matthias Schneider
Harald Bluhm
Christian Gege
Matthias Hochguertel
Carine Chevrier
Arthur Taveras
Original Assignee
Alantos Pharm Holding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alantos Pharm Holding filed Critical Alantos Pharm Holding
Publication of MX2009009552A publication Critical patent/MX2009009552A/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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Abstract

La presente invención se refiere generalmente a agentes farmacéuticos que contiene una porción heterocíclica, y en particular, a compuestos que inhiben la metaloproteasa heterocíclicos: Más particularmente, la presente invención proporciona una clase nueva de compuestos que inhiben MMP-13 heterocíclicos con una porción de benzoxazinona, que exhibe una potencia y selectividad incrementada en relación a inhibidores MMP-13 actualmente conocidos.
MX2009009552A 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica. MX2009009552A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90556507P 2007-03-07 2007-03-07
PCT/US2008/003195 WO2008109180A2 (en) 2007-03-07 2008-03-07 Metalloprotease inhibitors containing a heterocyclic moiety

Publications (1)

Publication Number Publication Date
MX2009009552A true MX2009009552A (es) 2009-09-28

Family

ID=39551667

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2009009541A MX2009009541A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.
MX2009009540A MX2009009540A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.
MX2009009552A MX2009009552A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2009009541A MX2009009541A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.
MX2009009540A MX2009009540A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.

Country Status (7)

Country Link
US (5) US7691851B2 (es)
EP (3) EP2125816A2 (es)
JP (3) JP2010520293A (es)
AU (3) AU2008223348A1 (es)
CA (3) CA2680173A1 (es)
MX (3) MX2009009541A (es)
WO (5) WO2008109178A1 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7728031B2 (en) * 2006-02-24 2010-06-01 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole derivatives
CA2670031A1 (en) * 2006-11-20 2008-05-29 Alantos Pharmaceuticals Holding, Inc. Heterobicyclic metalloprotease inhibitors
RU2486187C2 (ru) * 2007-09-11 2013-06-27 Эбботт Лэборетриз N-ОКСИДЫ ОКТАГИДРО-ПИРРОЛО[3,4-b]ПИРРОЛА
EP2271646A1 (en) 2008-03-31 2011-01-12 Takeda Pharmaceutical Company Limited Apoptosis signal-regulating kinase 1 inhibitors
WO2010014913A1 (en) 2008-08-01 2010-02-04 Ventirx Pharmaceuticals, Inc. Toll-like receptor agonist formulations and their use
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