MX2013003152A - Composiciones de bepotastina. - Google Patents
Composiciones de bepotastina.Info
- Publication number
- MX2013003152A MX2013003152A MX2013003152A MX2013003152A MX2013003152A MX 2013003152 A MX2013003152 A MX 2013003152A MX 2013003152 A MX2013003152 A MX 2013003152A MX 2013003152 A MX2013003152 A MX 2013003152A MX 2013003152 A MX2013003152 A MX 2013003152A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- bepotastine
- compositions including
- bepotastine compositions
- sorbitol
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- YWGDOWXRIALTES-NRFANRHFSA-N bepotastine Chemical compound C1CN(CCCC(=O)O)CCC1O[C@H](C=1N=CC=CC=1)C1=CC=C(Cl)C=C1 YWGDOWXRIALTES-NRFANRHFSA-N 0.000 title 1
- 229960002071 bepotastine Drugs 0.000 title 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- UDGHXQPQKQPSBB-UHFFFAOYSA-N benzenesulfonic acid;4-[4-[(4-chlorophenyl)-pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid Chemical compound OS(=O)(=O)C1=CC=CC=C1.C1CN(CCCC(=O)O)CCC1OC(C=1N=CC=CC=1)C1=CC=C(Cl)C=C1 UDGHXQPQKQPSBB-UHFFFAOYSA-N 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- 229960001105 bepotastine besilate Drugs 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Se proporcionan composiciones nuevas que incluyen besilato de bepotastina tales como composiciones libres de sorbitol, composiciones que incluyen por lo menos aproximadamente 0.008% peso/volumen de cloruro de benzalconio, y composiciones que incluyen hidroxipropil celulosa E15 LV.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39026210P | 2010-10-06 | 2010-10-06 | |
| PCT/US2011/055011 WO2012048059A2 (en) | 2010-10-06 | 2011-10-06 | Bepotastine compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013003152A true MX2013003152A (es) | 2013-08-15 |
| MX341109B MX341109B (es) | 2016-08-09 |
Family
ID=45928420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013003152A MX341109B (es) | 2010-10-06 | 2011-10-06 | Composiciones de bepotastina. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20130046240A1 (es) |
| EP (1) | EP2624836B1 (es) |
| JP (1) | JP5759553B2 (es) |
| KR (1) | KR20130099140A (es) |
| CN (1) | CN103260623B (es) |
| BR (1) | BR112013008244A8 (es) |
| CA (1) | CA2813748C (es) |
| ES (1) | ES2551752T3 (es) |
| HU (1) | HUE026106T2 (es) |
| MX (1) | MX341109B (es) |
| PL (1) | PL2624836T3 (es) |
| WO (1) | WO2012048059A2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103269687B (zh) * | 2011-01-04 | 2016-09-14 | 伊斯塔制药公司 | 贝托斯汀组合物 |
| KR101427611B1 (ko) * | 2011-03-08 | 2014-08-11 | 롬엔드하스전자재료코리아유한회사 | 신규한 유기 전자재료용 화합물 및 이를 포함하는 유기 전계 발광 소자 |
| KR20120109744A (ko) * | 2011-03-25 | 2012-10-09 | 롬엔드하스전자재료코리아유한회사 | 신규한 유기 전자재료용 화합물 및 이를 포함하는 유기 전계 발광 소자 |
| US20140171794A1 (en) * | 2012-12-13 | 2014-06-19 | James Liu | Method of a Liquid Surgery |
| CN103755626A (zh) * | 2014-01-23 | 2014-04-30 | 安徽安腾药业有限责任公司 | 一种贝托斯汀关键中间体的合成方法 |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039620B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| KR20190049023A (ko) * | 2017-11-01 | 2019-05-09 | (주)아이엠디팜 | 베포타스틴 또는 이의 약학적으로 허용가능한 염을 포함하는 방출제어 단일 매트릭스 정제 및 이의 제조방법 |
| CN112121013B (zh) * | 2020-10-23 | 2022-10-28 | 南京科默生物医药有限公司 | 一种药物组合物及其制备方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8902300D0 (en) * | 1989-02-02 | 1989-03-22 | Bryce Smith Derek | Antirhinoviral preparations |
| CN1222852A (zh) * | 1996-06-04 | 1999-07-14 | 普罗克特和甘保尔公司 | 含鼻内类固醇和抗组胺剂的鼻喷雾剂 |
| US6565832B1 (en) * | 2000-01-31 | 2003-05-20 | Schering-Plough Healthcare Products, Inc. | Spray composition with reduced dripping |
| AU2003252746A1 (en) * | 2002-07-31 | 2004-02-16 | Senju Pharmaceutical Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
| MXPA05001885A (es) * | 2002-08-30 | 2005-06-03 | Altana Pharma Ag | El uso de una combinacion de ciclesonida y antihistaminas para el tratamiento de la rinitis alergica. |
| US7188231B2 (en) * | 2003-06-30 | 2007-03-06 | Intel Corporation | Multimedia address generator |
| EP1827499A4 (en) * | 2004-11-24 | 2010-03-17 | Medpointe Healthcare Inc | COMPOSITIONS COMPRISING AZELASTIN AND METHODS OF USE |
| CN101257891A (zh) * | 2005-09-01 | 2008-09-03 | 比奥里波克斯公司 | 包含抗组胺剂以及皮质类固醇的脂质体组合物及其在制备治疗鼻炎以及相关疾病的药物中的用途 |
| KR100878698B1 (ko) * | 2007-04-05 | 2009-01-13 | 한미약품 주식회사 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및이를 포함하는 약학 조성물 |
| JP2010523695A (ja) * | 2007-04-11 | 2010-07-15 | アルコン リサーチ, リミテッド | アレルギー性鼻炎およびアレルギー性結膜炎を処置するためのTNFαのインヒビターおよび抗ヒスタミン薬の使用 |
| ES2493641T3 (es) * | 2007-06-28 | 2014-09-12 | Cydex Pharmaceuticals, Inc. | Administración nasal de soluciones acuosas de corticosteroides |
| US7707534B2 (en) * | 2007-07-25 | 2010-04-27 | Dell Products, Lp | Circuit board design tool and methods |
| KR20090061972A (ko) * | 2007-12-12 | 2009-06-17 | 한미약품 주식회사 | 베포타스틴 p-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물 |
| JP2009263298A (ja) * | 2008-04-28 | 2009-11-12 | Ss Pharmaceut Co Ltd | 不快な味を隠ぺいした経口組成物 |
| US20110200646A1 (en) * | 2008-09-02 | 2011-08-18 | Charanjit Bountra | The TRPVL Antagonists SB-795498 For Treating Rhinitis |
| JP2010195716A (ja) * | 2009-02-25 | 2010-09-09 | Takeda Chem Ind Ltd | 点鼻睡眠導入剤 |
| CN103269687B (zh) * | 2011-01-04 | 2016-09-14 | 伊斯塔制药公司 | 贝托斯汀组合物 |
-
2011
- 2011-10-06 PL PL11831558T patent/PL2624836T3/pl unknown
- 2011-10-06 HU HUE11831558A patent/HUE026106T2/en unknown
- 2011-10-06 EP EP11831558.9A patent/EP2624836B1/en not_active Not-in-force
- 2011-10-06 ES ES11831558.9T patent/ES2551752T3/es active Active
- 2011-10-06 WO PCT/US2011/055011 patent/WO2012048059A2/en not_active Ceased
- 2011-10-06 BR BR112013008244A patent/BR112013008244A8/pt active Search and Examination
- 2011-10-06 JP JP2013532933A patent/JP5759553B2/ja not_active Expired - Fee Related
- 2011-10-06 KR KR1020137011613A patent/KR20130099140A/ko not_active Ceased
- 2011-10-06 CN CN201180048106.3A patent/CN103260623B/zh not_active Expired - Fee Related
- 2011-10-06 MX MX2013003152A patent/MX341109B/es active IP Right Grant
- 2011-10-06 CA CA2813748A patent/CA2813748C/en not_active Expired - Fee Related
- 2011-10-06 US US13/505,426 patent/US20130046240A1/en not_active Abandoned
-
2012
- 2012-05-02 US US13/462,375 patent/US20120225905A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130046240A1 (en) | 2013-02-21 |
| ES2551752T3 (es) | 2015-11-23 |
| HUE026106T2 (en) | 2016-05-30 |
| PL2624836T3 (pl) | 2016-04-29 |
| EP2624836A2 (en) | 2013-08-14 |
| CA2813748C (en) | 2016-06-14 |
| KR20130099140A (ko) | 2013-09-05 |
| BR112013008244A8 (pt) | 2018-02-14 |
| EP2624836B1 (en) | 2015-09-23 |
| EP2624836A4 (en) | 2014-05-14 |
| CN103260623B (zh) | 2016-11-02 |
| WO2012048059A2 (en) | 2012-04-12 |
| JP5759553B2 (ja) | 2015-08-05 |
| CA2813748A1 (en) | 2012-04-12 |
| WO2012048059A3 (en) | 2012-05-31 |
| BR112013008244A2 (pt) | 2017-12-05 |
| CN103260623A (zh) | 2013-08-21 |
| JP2013539758A (ja) | 2013-10-28 |
| MX341109B (es) | 2016-08-09 |
| US20120225905A1 (en) | 2012-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |