MX2014014199A - Sistema y procedimiento de prediccion de la inmunogenicidad de un peptido. - Google Patents
Sistema y procedimiento de prediccion de la inmunogenicidad de un peptido.Info
- Publication number
- MX2014014199A MX2014014199A MX2014014199A MX2014014199A MX2014014199A MX 2014014199 A MX2014014199 A MX 2014014199A MX 2014014199 A MX2014014199 A MX 2014014199A MX 2014014199 A MX2014014199 A MX 2014014199A MX 2014014199 A MX2014014199 A MX 2014014199A
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- immunogenicity
- model
- predicting
- score
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Abstract
Se proporcionan un sistema, medio de almacenamiento legible por ordenador y procedimiento de predicción de la inmunogenicidad de un péptido. En ciertos casos el sistema incluye: a) un modelo de un péptido, un modelo de una proteína del MHCII y un modelo de un receptor de linfocitos T; y b) un programa ejecutable para: (i) evaluar la intensidad de las interacciones intermoleculares de un complejo que contiene el péptido, la proteína del MHCII y el receptor de linfocitos T para proporcionar una puntuación que predice la inmunogenicidad del péptido; y (ii) generar la puntuación.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261652076P | 2012-05-25 | 2012-05-25 | |
| PCT/US2013/031661 WO2013176756A1 (en) | 2012-05-25 | 2013-03-14 | System and method for predicting the immunogenicity of a peptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014014199A true MX2014014199A (es) | 2015-02-12 |
Family
ID=49624222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014014199A MX2014014199A (es) | 2012-05-25 | 2013-03-14 | Sistema y procedimiento de prediccion de la inmunogenicidad de un peptido. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20150205911A1 (es) |
| EP (1) | EP2856374A4 (es) |
| JP (1) | JP2015526775A (es) |
| KR (1) | KR20150021528A (es) |
| CN (1) | CN104487979A (es) |
| AU (1) | AU2013266850A1 (es) |
| BR (1) | BR112014029235A2 (es) |
| CA (1) | CA2874542A1 (es) |
| IL (1) | IL235815A0 (es) |
| MX (1) | MX2014014199A (es) |
| NZ (1) | NZ702084A (es) |
| RU (1) | RU2014152463A (es) |
| SG (1) | SG11201407459QA (es) |
| WO (1) | WO2013176756A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3294324A1 (en) | 2015-05-13 | 2018-03-21 | Agenus Inc. | Vaccines for treatment and prevention of cancer |
| GB201607521D0 (en) * | 2016-04-29 | 2016-06-15 | Oncolmmunity As | Method |
| EP3776557B1 (en) * | 2018-04-13 | 2025-01-29 | The Hong Kong Polytechnic University | Data storage using peptides |
| KR20210005646A (ko) | 2018-04-26 | 2021-01-14 | 아게누스 인코포레이티드 | 열쇼크 단백질-결합 펩티드 조성물 및 그의 이용 방법 |
| CN109002689B (zh) * | 2018-07-23 | 2020-10-09 | 西安交通大学医学院第一附属医院 | T细胞数据处理方法及装置 |
| EP3894188A4 (en) * | 2018-12-10 | 2022-11-16 | University of Notre Dame du Lac | PREDICTION OF AFFINITY USING STRUCTURAL AND PHYSICAL MODELING |
| EP3909052A4 (en) * | 2018-12-10 | 2022-10-26 | University of Notre Dame du Lac | PREDICTION OF IMMUNOGENIC PEPTIDES USING STRUCTURAL AND PHYSICAL MODELING |
| CN110007067A (zh) * | 2019-03-11 | 2019-07-12 | 江苏理工学院 | 一种蛋白质分子对接检测装置 |
| KR102425492B1 (ko) * | 2020-04-27 | 2022-07-26 | 한림대학교 산학협력단 | Sars-cov-2 바이러스에 대한 에피토프 기반 펩타이드 백신의 개발 방법 |
| US20220130490A1 (en) * | 2020-10-27 | 2022-04-28 | Nec Laboratories America, Inc. | Peptide-based vaccine generation |
| CN115273969B (zh) * | 2022-06-22 | 2026-01-23 | 大连工业大学 | 一种具有抑制凝血因子Xa活性的多肽的快速虚拟筛选方法 |
| WO2023249440A1 (ko) * | 2022-06-24 | 2023-12-28 | 지니너스 주식회사 | 펩타이드와 t 세포 수용체간의 결합을 추정하는 방법 및 장치 |
| KR102611717B1 (ko) * | 2022-11-08 | 2023-12-08 | 주식회사 제로믹스 | 면역원성 에피토프를 예측하는 방법 및 이를 이용한 장치 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998052976A1 (en) * | 1997-05-21 | 1998-11-26 | Biovation Limited | Method for the production of non-immunogenic proteins |
| CA2415902A1 (en) * | 2000-07-10 | 2002-01-17 | Xencor | Protein design automation for designing protein libraries with altered immunogenicity |
| CA2452824A1 (en) * | 2001-07-10 | 2003-01-23 | Xencor | Protein design automation for designing protein libraries with altered immunogenicity |
| US20040230380A1 (en) * | 2002-01-04 | 2004-11-18 | Xencor | Novel proteins with altered immunogenicity |
| WO2006124408A2 (en) * | 2005-05-12 | 2006-11-23 | Merck & Co., Inc. | System and method for automated selection of t-cell epitopes |
| US8131480B2 (en) * | 2006-10-02 | 2012-03-06 | Sea Lane Biotechnologies Llc | Construction of diverse synthetic peptide and polypeptide libraries |
| WO2009042895A2 (en) * | 2007-09-26 | 2009-04-02 | Dana-Farber Cancer Institute, Inc. | Reagents for inducing an immune response |
| CN101289496B (zh) * | 2008-05-30 | 2011-06-29 | 中国医学科学院医学生物学研究所 | 能激发机体抗结核杆菌的保护性免疫反应的抗原表位筛选方法及用途 |
-
2013
- 2013-03-14 MX MX2014014199A patent/MX2014014199A/es unknown
- 2013-03-14 SG SG11201407459QA patent/SG11201407459QA/en unknown
- 2013-03-14 RU RU2014152463A patent/RU2014152463A/ru not_active Application Discontinuation
- 2013-03-14 NZ NZ702084A patent/NZ702084A/en not_active IP Right Cessation
- 2013-03-14 EP EP13793593.8A patent/EP2856374A4/en not_active Withdrawn
- 2013-03-14 CN CN201380039722.1A patent/CN104487979A/zh active Pending
- 2013-03-14 KR KR20147035884A patent/KR20150021528A/ko not_active Withdrawn
- 2013-03-14 BR BR112014029235A patent/BR112014029235A2/pt not_active IP Right Cessation
- 2013-03-14 WO PCT/US2013/031661 patent/WO2013176756A1/en not_active Ceased
- 2013-03-14 JP JP2015514009A patent/JP2015526775A/ja active Pending
- 2013-03-14 CA CA2874542A patent/CA2874542A1/en not_active Abandoned
- 2013-03-14 US US14/398,965 patent/US20150205911A1/en not_active Abandoned
- 2013-03-14 AU AU2013266850A patent/AU2013266850A1/en not_active Abandoned
-
2014
- 2014-11-20 IL IL235815A patent/IL235815A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013176756A1 (en) | 2013-11-28 |
| NZ702084A (en) | 2016-09-30 |
| KR20150021528A (ko) | 2015-03-02 |
| JP2015526775A (ja) | 2015-09-10 |
| US20150205911A1 (en) | 2015-07-23 |
| EP2856374A1 (en) | 2015-04-08 |
| CN104487979A (zh) | 2015-04-01 |
| BR112014029235A2 (pt) | 2019-01-29 |
| AU2013266850A1 (en) | 2014-12-04 |
| SG11201407459QA (en) | 2014-12-30 |
| CA2874542A1 (en) | 2013-11-28 |
| EP2856374A4 (en) | 2016-04-20 |
| RU2014152463A (ru) | 2016-07-20 |
| IL235815A0 (en) | 2015-01-29 |
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