MX2016009751A - Agente mejorador del efecto de la rehabilitacion despues de una lesion nerviosa que comprende un derivado de eter de alquilo o una sal del mismo. - Google Patents
Agente mejorador del efecto de la rehabilitacion despues de una lesion nerviosa que comprende un derivado de eter de alquilo o una sal del mismo.Info
- Publication number
- MX2016009751A MX2016009751A MX2016009751A MX2016009751A MX2016009751A MX 2016009751 A MX2016009751 A MX 2016009751A MX 2016009751 A MX2016009751 A MX 2016009751A MX 2016009751 A MX2016009751 A MX 2016009751A MX 2016009751 A MX2016009751 A MX 2016009751A
- Authority
- MX
- Mexico
- Prior art keywords
- salt
- alkyl ether
- enhancing agent
- nerve injury
- ether derivative
- Prior art date
Links
- 208000028389 Nerve injury Diseases 0.000 title abstract 2
- 150000005215 alkyl ethers Chemical class 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 230000008764 nerve damage Effects 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se proporciona una composición medicinal caracterizada porque comprende un derivado de éter de alquilo representado por la fórmula general [1] (ver Fórmula) en donde R1 y R2 son los mismos o diferentes y representan un átomo de hidrógeno, un átomo de halógeno, un grupo alquilo C1-6 opcionalmente sustituido, un grupo arilo opcionalmente sustituido, etc.; R3 representa un grupo hidroxilo opcionalmente protegido; etc., y m y n son los mismos o diferentes, y representan un número entero desde 1 hasta 6] o una sal del mismo. La composición medicinal de acuerdo con la presente invención es útil como un agente mejorador del efecto de la rehabilitación después de una lesión nerviosa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014017587 | 2014-01-31 | ||
| PCT/JP2015/052617 WO2015115582A1 (ja) | 2014-01-31 | 2015-01-30 | アルキルエーテル誘導体またはその塩を含有する神経損傷後のリハビリテーション効果促進剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016009751A true MX2016009751A (es) | 2016-11-08 |
Family
ID=53757150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016009751A MX2016009751A (es) | 2014-01-31 | 2015-01-30 | Agente mejorador del efecto de la rehabilitacion despues de una lesion nerviosa que comprende un derivado de eter de alquilo o una sal del mismo. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US10039744B2 (es) |
| EP (1) | EP3100725B1 (es) |
| JP (3) | JP5837726B1 (es) |
| KR (1) | KR102346219B1 (es) |
| CN (1) | CN106061478B (es) |
| AU (1) | AU2015211753B2 (es) |
| BR (1) | BR112016017747A2 (es) |
| CA (1) | CA2938184C (es) |
| CY (1) | CY1123154T1 (es) |
| DK (1) | DK3100725T3 (es) |
| ES (1) | ES2792950T3 (es) |
| HR (1) | HRP20200796T1 (es) |
| HU (1) | HUE050400T2 (es) |
| IL (1) | IL246925B (es) |
| LT (1) | LT3100725T (es) |
| MX (1) | MX2016009751A (es) |
| MY (1) | MY179290A (es) |
| PH (1) | PH12016501507A1 (es) |
| PL (1) | PL3100725T3 (es) |
| PT (1) | PT3100725T (es) |
| RS (1) | RS60462B1 (es) |
| RU (1) | RU2680247C2 (es) |
| SG (2) | SG11201606173TA (es) |
| SI (1) | SI3100725T1 (es) |
| SM (1) | SMT202000395T1 (es) |
| WO (1) | WO2015115582A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112016017747A2 (pt) * | 2014-01-31 | 2017-08-08 | Toyama Chemical Co Ltd | Agente de intensificação de efeito de reabilitação pós lesão de nervo compreendendo derivados de éter de alquila ou sal do mesmo |
| CA3009152C (en) | 2015-12-25 | 2023-08-15 | Toyama Chemical Co., Ltd. | Tablet comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salt thereof |
| JP7057286B2 (ja) * | 2016-12-28 | 2022-04-19 | 富士フイルム富山化学株式会社 | 医薬組成物 |
| CN110121342A (zh) * | 2016-12-28 | 2019-08-13 | 富士胶片富山化学株式会社 | 医药组合物 |
| US20190343796A1 (en) * | 2016-12-28 | 2019-11-14 | Fujifilm Toyama Chemical Co., Ltd. | Composition for external use |
| US11234962B2 (en) | 2016-12-28 | 2022-02-01 | Fujifilm Toyama Chemical Co., Ltd. | Pharmaceutical composition and method of manufacturing the same |
| CA3067455C (en) * | 2017-06-02 | 2021-11-23 | Fujifilm Toyama Chemical Co., Ltd. | Agent for preventing or treating spinocerebellar ataxia |
| JP7370859B2 (ja) * | 2017-06-02 | 2023-10-30 | 富士フイルム富山化学株式会社 | タウオパチー予防または治療剤 |
| KR20190137936A (ko) * | 2017-06-02 | 2019-12-11 | 후지필름 도야마 케미컬 가부시키가이샤 | 뇌 위축 예방 또는 치료제 |
| US11541033B2 (en) | 2017-06-02 | 2023-01-03 | Fujifilm Toyama Chemical Co., Ltd. | Agent for preventing or treating Alzheimer's disease |
| MX393006B (es) * | 2017-06-02 | 2025-03-24 | Fujifilm Toyama Chemical Co Ltd | Agente para reducir la cantidad de proteina beta amiloide. |
| JP7227914B2 (ja) | 2017-10-30 | 2023-02-22 | 富士フイルム富山化学株式会社 | エモパミル結合タンパク質結合剤およびその利用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0213393B8 (pt) * | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| WO2003045137A1 (fr) * | 2001-11-29 | 2003-06-05 | Japan Science And Technology Agency | Procede de construction d'un modele simien de lesion spinale et son utilisation |
| HUE041842T2 (hu) | 2002-06-14 | 2019-05-28 | Toyama Chemical Co Ltd | Gyógyászati készítmény agymûködés javítására |
| ES2391273T3 (es) | 2003-04-17 | 2012-11-23 | Toyama Chemical Co., Ltd. | Agente preventivo/curativo para enfermedades del nervio retiniano que contiene derivados de éter alquílico o sus sales |
| SI2248809T1 (sl) | 2005-03-28 | 2012-09-28 | Toyama Chemical Co Ltd | Alkil-3-(2-(benzo(b)tiofen-5-il)-etoksi)-propanoati kot vmesniki v proizvodnji derivatov azetidin-3-ola |
| RU2397169C2 (ru) * | 2005-03-28 | 2010-08-20 | Тояма Кемикал Ко., Лтд. | Способ получения 1-(3-(2-(1-бензотиофен-5-ил)этокси) пропил)азетидин-3-ола или его солей |
| CA2648898C (en) * | 2006-04-26 | 2015-01-20 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
| US8119625B2 (en) * | 2006-04-26 | 2012-02-21 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
| BR112016017747A2 (pt) * | 2014-01-31 | 2017-08-08 | Toyama Chemical Co Ltd | Agente de intensificação de efeito de reabilitação pós lesão de nervo compreendendo derivados de éter de alquila ou sal do mesmo |
-
2015
- 2015-01-30 BR BR112016017747A patent/BR112016017747A2/pt not_active Application Discontinuation
- 2015-01-30 DK DK15743367.3T patent/DK3100725T3/da active
- 2015-01-30 HU HUE15743367A patent/HUE050400T2/hu unknown
- 2015-01-30 MX MX2016009751A patent/MX2016009751A/es active IP Right Grant
- 2015-01-30 SG SG11201606173TA patent/SG11201606173TA/en unknown
- 2015-01-30 JP JP2015539315A patent/JP5837726B1/ja active Active
- 2015-01-30 AU AU2015211753A patent/AU2015211753B2/en active Active
- 2015-01-30 SI SI201531278T patent/SI3100725T1/sl unknown
- 2015-01-30 MY MYPI2016702668A patent/MY179290A/en unknown
- 2015-01-30 ES ES15743367T patent/ES2792950T3/es active Active
- 2015-01-30 KR KR1020167023717A patent/KR102346219B1/ko active Active
- 2015-01-30 PT PT157433673T patent/PT3100725T/pt unknown
- 2015-01-30 US US15/115,416 patent/US10039744B2/en active Active
- 2015-01-30 EP EP15743367.3A patent/EP3100725B1/en active Active
- 2015-01-30 SM SM20200395T patent/SMT202000395T1/it unknown
- 2015-01-30 RS RS20200754A patent/RS60462B1/sr unknown
- 2015-01-30 PL PL15743367T patent/PL3100725T3/pl unknown
- 2015-01-30 CN CN201580011450.3A patent/CN106061478B/zh active Active
- 2015-01-30 WO PCT/JP2015/052617 patent/WO2015115582A1/ja not_active Ceased
- 2015-01-30 SG SG10201907035TA patent/SG10201907035TA/en unknown
- 2015-01-30 CA CA2938184A patent/CA2938184C/en active Active
- 2015-01-30 RU RU2016135236A patent/RU2680247C2/ru active
- 2015-01-30 LT LTEP15743367.3T patent/LT3100725T/lt unknown
- 2015-01-30 HR HRP20200796TT patent/HRP20200796T1/hr unknown
- 2015-11-04 JP JP2015216722A patent/JP6642914B2/ja active Active
-
2016
- 2016-07-25 IL IL24692516A patent/IL246925B/en active IP Right Grant
- 2016-07-29 PH PH12016501507A patent/PH12016501507A1/en unknown
-
2018
- 2018-06-12 US US16/005,774 patent/US10471044B2/en active Active
-
2019
- 2019-12-26 JP JP2019236541A patent/JP6825074B2/ja active Active
-
2020
- 2020-07-23 CY CY20201100673T patent/CY1123154T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |