MX2017003516A - Derivados de pirazol como estimuladores de guanilato ciclasa soluble (sgc). - Google Patents

Derivados de pirazol como estimuladores de guanilato ciclasa soluble (sgc).

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Publication number
MX2017003516A
MX2017003516A MX2017003516A MX2017003516A MX2017003516A MX 2017003516 A MX2017003516 A MX 2017003516A MX 2017003516 A MX2017003516 A MX 2017003516A MX 2017003516 A MX2017003516 A MX 2017003516A MX 2017003516 A MX2017003516 A MX 2017003516A
Authority
MX
Mexico
Prior art keywords
pyrazole derivatives
sgc stimulators
stimulators
sgc
useful
Prior art date
Application number
MX2017003516A
Other languages
English (en)
Inventor
Wai-Ho Lee Thomas
Mermerian Ara
Jia James
Nakai Takashi
Robert Rennie Glen
Claude Barden Timothy
Edward Sheppeck James
Iyer Karthik
Jung Joon
Allan RENHOWE Paul
Perl Nicholas
Yoon Jamie Im G-
R Iyengar Rajesh
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MX2017003516A publication Critical patent/MX2017003516A/es

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Abstract

Allí se describen los derivados de imidazol y pirazol que son utilies como estimuladores de sGC, particularmente estimuladores independientes de NO, dependientes de heme. Estos compuestos además son utilies para tratar, prevenir o manejar diversos trastornos que se describen en la presente descripción.
MX2017003516A 2014-09-17 2015-09-16 Derivados de pirazol como estimuladores de guanilato ciclasa soluble (sgc). MX2017003516A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462051557P 2014-09-17 2014-09-17
US201562204710P 2015-08-13 2015-08-13
PCT/US2015/050468 WO2016044447A1 (en) 2014-09-17 2015-09-16 Pyrazole derivatives as sgc stimulators

Publications (1)

Publication Number Publication Date
MX2017003516A true MX2017003516A (es) 2017-07-28

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MX2017003516A MX2017003516A (es) 2014-09-17 2015-09-16 Derivados de pirazol como estimuladores de guanilato ciclasa soluble (sgc).

Country Status (8)

Country Link
US (4) US20170291889A1 (es)
EP (1) EP3194382B1 (es)
JP (1) JP6624616B2 (es)
CN (1) CN107406422B (es)
AU (2) AU2015317824A1 (es)
CA (1) CA2959757A1 (es)
MX (1) MX2017003516A (es)
WO (1) WO2016044447A1 (es)

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CN110577467A (zh) * 2019-09-18 2019-12-17 重庆医药高等专科学校 一种3-羟基丙酸的合成方法
WO2021125345A1 (ja) * 2019-12-18 2021-06-24 株式会社バイオラジカル研究所 血管拡張剤およびその用途
CN112007027B (zh) * 2020-09-14 2022-07-15 长春金赛药业有限责任公司 含酯基芳香丙酰胺类化合物及其代谢产物在制备治疗心衰药物中的应用
CN112169717B (zh) * 2020-09-30 2022-06-03 深圳大学 一种微胶囊化氯化血红素及其制备方法与应用
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US20190031641A1 (en) 2019-01-31
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