MX2017005243A - Reducción de la viscosidad de formulaciones farmacéuticas. - Google Patents

Reducción de la viscosidad de formulaciones farmacéuticas.

Info

Publication number
MX2017005243A
MX2017005243A MX2017005243A MX2017005243A MX2017005243A MX 2017005243 A MX2017005243 A MX 2017005243A MX 2017005243 A MX2017005243 A MX 2017005243A MX 2017005243 A MX2017005243 A MX 2017005243A MX 2017005243 A MX2017005243 A MX 2017005243A
Authority
MX
Mexico
Prior art keywords
pharmaceutical formulations
reducing viscosity
acetyl
viscosity
pharmaceutical formulation
Prior art date
Application number
MX2017005243A
Other languages
English (en)
Other versions
MX388858B (es
Inventor
James Sloey Christopher
KANAPURAM Sekhar
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54427875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017005243(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2017005243A publication Critical patent/MX2017005243A/es
Publication of MX388858B publication Critical patent/MX388858B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se proporciona un método para reducir la viscosidad de una formulación farmacéutica que utiliza una concentración de reducción de la viscosidad de un excipiente seleccionado del grupo que consiste de la n-acetil arginina, n-acetil lisina, n-acetil prolina y mezclas de los mismos en combinación con una proteína terapéutica. También se proporciona una formulación farmacéutica estable.
MX2017005243A 2014-10-23 2015-10-22 Reducción de la viscosidad de formulaciones farmacéuticas MX388858B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462067637P 2014-10-23 2014-10-23
PCT/US2015/056972 WO2016065181A1 (en) 2014-10-23 2015-10-22 Reducing viscosity of pharmaceutical formulations

Publications (2)

Publication Number Publication Date
MX2017005243A true MX2017005243A (es) 2017-08-18
MX388858B MX388858B (es) 2025-03-20

Family

ID=54427875

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017005243A MX388858B (es) 2014-10-23 2015-10-22 Reducción de la viscosidad de formulaciones farmacéuticas
MX2021015789A MX2021015789A (es) 2014-10-23 2017-04-21 Reduccion de la viscosidad de formulaciones farmaceuticas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021015789A MX2021015789A (es) 2014-10-23 2017-04-21 Reduccion de la viscosidad de formulaciones farmaceuticas.

Country Status (17)

Country Link
US (3) US11813328B2 (es)
EP (2) EP3209332B1 (es)
JP (3) JP2017531682A (es)
KR (1) KR102534017B1 (es)
CN (2) CN107206070B (es)
AU (2) AU2015335743B2 (es)
BR (1) BR112017008125B1 (es)
CA (1) CA2964786C (es)
CL (2) CL2017000984A1 (es)
EA (3) EA038462B1 (es)
ES (1) ES2964713T3 (es)
IL (2) IL287947B2 (es)
MA (1) MA54716A (es)
MX (2) MX388858B (es)
SG (1) SG11201703152RA (es)
WO (1) WO2016065181A1 (es)
ZA (1) ZA201702762B (es)

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Also Published As

Publication number Publication date
US12318447B2 (en) 2025-06-03
CA2964786A1 (en) 2016-04-28
EP3909611B1 (en) 2023-08-30
US20170333559A1 (en) 2017-11-23
ZA201702762B (en) 2022-12-21
JP7411615B2 (ja) 2024-01-11
BR112017008125B1 (pt) 2023-11-21
EA038462B1 (ru) 2021-08-31
US11813328B2 (en) 2023-11-14
EP3209332A1 (en) 2017-08-30
IL287947A (en) 2022-01-01
MA54716A (fr) 2021-11-17
AU2015335743B2 (en) 2020-12-24
US20250345421A1 (en) 2025-11-13
JP2020037559A (ja) 2020-03-12
JP2017531682A (ja) 2017-10-26
EA201790787A1 (ru) 2017-08-31
BR112017008125A2 (pt) 2018-06-19
CN114569716A (zh) 2022-06-03
CN107206070B (zh) 2022-01-18
SG11201703152RA (en) 2017-05-30
AU2015335743A1 (en) 2017-05-04
JP6965321B2 (ja) 2021-11-10
EP3209332B1 (en) 2021-05-26
CL2019002190A1 (es) 2019-11-22
IL251726A0 (en) 2017-06-29
MX388858B (es) 2025-03-20
IL287947B2 (en) 2024-08-01
KR20170071518A (ko) 2017-06-23
US20240066124A1 (en) 2024-02-29
CA2964786C (en) 2023-10-17
EP3909611A1 (en) 2021-11-17
CL2017000984A1 (es) 2018-01-05
KR102534017B1 (ko) 2023-05-19
AU2021200990A1 (en) 2021-03-11
JP2022009223A (ja) 2022-01-14
IL287947B1 (en) 2024-04-01
WO2016065181A1 (en) 2016-04-28
AU2021200990B2 (en) 2023-02-16
EA201991447A1 (ru) 2019-11-29
CN107206070A (zh) 2017-09-26
ES2964713T3 (es) 2024-04-09
MX2021015789A (es) 2022-01-27
IL251726B (en) 2021-12-01
EA202191513A1 (ru) 2021-11-30
EA033444B1 (ru) 2019-10-31

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