MX2017007747A - Anticuerpos para il-17c. - Google Patents

Anticuerpos para il-17c.

Info

Publication number
MX2017007747A
MX2017007747A MX2017007747A MX2017007747A MX2017007747A MX 2017007747 A MX2017007747 A MX 2017007747A MX 2017007747 A MX2017007747 A MX 2017007747A MX 2017007747 A MX2017007747 A MX 2017007747A MX 2017007747 A MX2017007747 A MX 2017007747A
Authority
MX
Mexico
Prior art keywords
antibodies
antibody fragments
homodimeric
human
relates
Prior art date
Application number
MX2017007747A
Other languages
English (en)
Inventor
Garcia Teresa
Klattig Jürgen
Ernest René Vandeghinste Nick
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of MX2017007747A publication Critical patent/MX2017007747A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/35—Valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención proporciona anticuerpos o fragmentos de anticuerpos que se unen a IL-17C humana. En particular, se refiere a anticuerpos o fragmentos de anticuerpos que se unen bivalentemente a IL-17C homodimérica.
MX2017007747A 2014-12-15 2015-12-15 Anticuerpos para il-17c. MX2017007747A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14197883 2014-12-15
PCT/EP2015/079856 WO2016096896A1 (en) 2014-12-15 2015-12-15 Antibodies for il-17c

Publications (1)

Publication Number Publication Date
MX2017007747A true MX2017007747A (es) 2018-02-13

Family

ID=52101155

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017007747A MX2017007747A (es) 2014-12-15 2015-12-15 Anticuerpos para il-17c.

Country Status (14)

Country Link
US (2) US20170342147A1 (es)
EP (1) EP3233915B1 (es)
JP (1) JP6944747B2 (es)
KR (1) KR20170089013A (es)
CN (1) CN107108728A (es)
AU (1) AU2015367684A1 (es)
CA (1) CA2970759A1 (es)
DK (1) DK3233915T3 (es)
IL (1) IL252875B (es)
MX (1) MX2017007747A (es)
RU (1) RU2017122172A (es)
SG (1) SG11201704861WA (es)
WO (1) WO2016096896A1 (es)
ZA (1) ZA201704704B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201806161TA (en) * 2016-02-19 2018-08-30 Morphosys Ag Antibodies for il-17c
IL270244B2 (en) * 2017-05-05 2025-01-01 Vaccinex Inc Antibody against human semaphorin 4D
EP3688031A1 (en) * 2017-09-25 2020-08-05 MorphoSys AG Treatment of atopic dermatitis
GB201803563D0 (en) * 2018-03-06 2018-04-18 Galapagos Nv Antibodies and pharmaceutical compositions thereof for the treatment of autoimmune skin diseases
IL292940A (en) * 2019-11-22 2022-07-01 Morphosys Ag Collection of extractant during antibody chromatography

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU740405B2 (en) * 1998-05-15 2001-11-01 Genentech Inc. IL-17 homologous polypeptides and therapeutic uses thereof
CA2624763A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
CA2721713C (en) * 2008-05-05 2019-07-09 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
JP5922025B2 (ja) * 2009-10-30 2016-05-25 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ−１７ａ拮抗物質
CN102711829B (zh) * 2009-11-30 2016-03-16 生物测试股份公司 治疗系统性红斑狼疮(sle)的人源化抗il-10抗体
US20120201821A1 (en) * 2010-10-25 2012-08-09 Gonzalez Jr Lino Treatment of Gastrointestinal Inflammation and Psoriasis and Asthma
EP2659275B1 (en) * 2010-12-23 2017-11-22 Roche Diagnostics GmbH Detection of a polypeptide dimer by a bivalent binding agent
SG11201401202YA (en) * 2011-10-19 2014-06-27 Morphosys Ag Antagonists of il17c for the treatment of inflammatory disorders

Also Published As

Publication number Publication date
SG11201704861WA (en) 2017-07-28
JP6944747B2 (ja) 2021-10-06
US20170342147A1 (en) 2017-11-30
KR20170089013A (ko) 2017-08-02
WO2016096896A1 (en) 2016-06-23
EP3233915B1 (en) 2024-08-28
CA2970759A1 (en) 2016-06-23
RU2017122172A (ru) 2019-01-17
RU2017122172A3 (es) 2019-07-17
CN107108728A (zh) 2017-08-29
DK3233915T3 (da) 2024-09-30
IL252875A0 (en) 2017-08-31
IL252875B (en) 2021-04-29
JP2018506296A (ja) 2018-03-08
AU2015367684A1 (en) 2017-07-06
ZA201704704B (en) 2019-10-30
US20200010542A1 (en) 2020-01-09
EP3233915A1 (en) 2017-10-25

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