MX2017011981A - Terapias novedosas para cancer. - Google Patents

Terapias novedosas para cancer.

Info

Publication number
MX2017011981A
MX2017011981A MX2017011981A MX2017011981A MX2017011981A MX 2017011981 A MX2017011981 A MX 2017011981A MX 2017011981 A MX2017011981 A MX 2017011981A MX 2017011981 A MX2017011981 A MX 2017011981A MX 2017011981 A MX2017011981 A MX 2017011981A
Authority
MX
Mexico
Prior art keywords
cancer
novel therapies
treatment
relates
diazepan
Prior art date
Application number
MX2017011981A
Other languages
English (en)
Other versions
MX377817B (es
Inventor
Richardson Peter
Festuccia Claudio
Mary Walling Jacqueline
Original Assignee
Proximagen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proximagen Ltd filed Critical Proximagen Ltd
Publication of MX2017011981A publication Critical patent/MX2017011981A/es
Publication of MX377817B publication Critical patent/MX377817B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se relaciona a 6-{4-[1-(propan-2-il)-piperidin-4-il]- 1,4-diazepan-1-il}-N-(piridin-4-il)piridin-2-carboxamida, o una sal farmacéuticamente aceptable de la misma, para el uso en el tratamiento de cánceres del CNS. La invención también se relaciona a tratamientos de combinación con irradiación y/o un agente quimioterapéutico para el uso en el tratamiento de cáncer.
MX2017011981A 2015-04-02 2016-04-01 Terapias novedosas para cancer. MX377817B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562141980P 2015-04-02 2015-04-02
PCT/IB2016/051880 WO2016157149A1 (en) 2015-04-02 2016-04-01 Novel therapies for cancer

Publications (2)

Publication Number Publication Date
MX2017011981A true MX2017011981A (es) 2018-01-10
MX377817B MX377817B (es) 2025-03-11

Family

ID=55702039

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011981A MX377817B (es) 2015-04-02 2016-04-01 Terapias novedosas para cancer.

Country Status (18)

Country Link
US (1) US11311552B2 (es)
EP (1) EP3277284B1 (es)
JP (1) JP6927882B2 (es)
KR (1) KR20170132314A (es)
CN (2) CN112569242A (es)
AU (1) AU2016242118B2 (es)
BR (1) BR112017019437A2 (es)
CA (1) CA2979167A1 (es)
DK (1) DK3277284T3 (es)
EA (1) EA037555B1 (es)
ES (1) ES2826558T3 (es)
HU (1) HUE051341T2 (es)
IL (1) IL254149A0 (es)
MX (1) MX377817B (es)
PL (1) PL3277284T3 (es)
PT (1) PT3277284T (es)
SG (2) SG10201909188XA (es)
WO (1) WO2016157149A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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GB201017345D0 (en) 2010-10-14 2010-11-24 Proximagen Ltd Receptor antagonists
JP6927882B2 (ja) 2015-04-02 2021-09-01 プロキシマジェン，リミティド ライアビリティ カンパニー 癌の新治療法
GB201604213D0 (en) * 2016-03-11 2016-04-27 Proximagen Ltd Drug combination and its use in therapy
GB201703907D0 (en) * 2017-03-10 2017-04-26 Proximagen Ltd Novel therapies for cancer
WO2020222189A1 (en) 2019-05-02 2020-11-05 Proximagen, Llc Crystalline form of 6-[4-[1-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl]-n-(pyrdin-4-yl)pyridine-2-carboxamide
WO2020222190A1 (en) 2019-05-02 2020-11-05 Proximagen, Llc Crystalline form of 6-[4-[1 -(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1 -yl]-n-(pyrdin-4-yl)pyridine-2-carboxamide
JP7327855B2 (ja) 2020-06-26 2023-08-16 ラクオリア創薬株式会社 レチノイドとがん治療薬との併用療法が有効ながん患者の選択方法およびレチノイドとがん治療薬との併用医薬

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Also Published As

Publication number Publication date
CN107438437B (zh) 2021-01-01
SG10201909188XA (en) 2019-11-28
US11311552B2 (en) 2022-04-26
EA201791953A1 (ru) 2018-01-31
EP3277284A1 (en) 2018-02-07
JP2018510154A (ja) 2018-04-12
AU2016242118A1 (en) 2017-10-05
EA037555B1 (ru) 2021-04-13
CN112569242A (zh) 2021-03-30
US20180078563A1 (en) 2018-03-22
WO2016157149A9 (en) 2016-12-08
PT3277284T (pt) 2020-11-11
SG11201707429VA (en) 2017-10-30
ES2826558T3 (es) 2021-05-18
AU2016242118B2 (en) 2021-07-08
HK1245120A1 (en) 2018-08-24
CN107438437A (zh) 2017-12-05
BR112017019437A2 (pt) 2018-05-02
CA2979167A1 (en) 2016-10-06
DK3277284T3 (da) 2020-10-26
KR20170132314A (ko) 2017-12-01
HUE051341T2 (hu) 2021-03-01
MX377817B (es) 2025-03-11
WO2016157149A1 (en) 2016-10-06
IL254149A0 (en) 2017-10-31
EP3277284B1 (en) 2020-08-05
PL3277284T3 (pl) 2021-03-08
JP6927882B2 (ja) 2021-09-01

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