MX2017013855A - Metodo para la separacion de proteina y otras impurezas de polisacaridos capsulares microbianos. - Google Patents

Metodo para la separacion de proteina y otras impurezas de polisacaridos capsulares microbianos.

Info

Publication number
MX2017013855A
MX2017013855A MX2017013855A MX2017013855A MX2017013855A MX 2017013855 A MX2017013855 A MX 2017013855A MX 2017013855 A MX2017013855 A MX 2017013855A MX 2017013855 A MX2017013855 A MX 2017013855A MX 2017013855 A MX2017013855 A MX 2017013855A
Authority
MX
Mexico
Prior art keywords
impurities
protein
capsular polysaccharides
separation
microbial capsular
Prior art date
Application number
MX2017013855A
Other languages
English (en)
Other versions
MX394142B (es
Inventor
Datla Mahima
Venkat Matur Ramesh
Venkateswara Reddy Muthyala
Charan Kantam
Dev Mantena Narender
Babu Kandimalla Vivek
Original Assignee
Biological E Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biological E Ltd filed Critical Biological E Ltd
Publication of MX2017013855A publication Critical patent/MX2017013855A/es
Publication of MX394142B publication Critical patent/MX394142B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La invención se refiere a un método para la eliminación de proteínas y otras impurezas de polisacáridos capsulares microbianos. Más particularmente, la presente invención se refiere al aislamiento de polisacáridos capsulares microbianos en forma pura después de la eliminación de proteínas y otras impurezas.
MX2017013855A 2015-04-28 2016-04-25 Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos. MX394142B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2161CH2015 2015-04-28
PCT/IN2016/000107 WO2016174683A1 (en) 2015-04-28 2016-04-25 Method for separation of protein and other impurities from microbial capsular polysaccharides

Publications (2)

Publication Number Publication Date
MX2017013855A true MX2017013855A (es) 2018-03-15
MX394142B MX394142B (es) 2025-03-24

Family

ID=56137482

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017013855A MX394142B (es) 2015-04-28 2016-04-25 Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos.

Country Status (12)

Country Link
US (2) US10836839B2 (es)
EP (1) EP3288983B1 (es)
JP (1) JP6882193B2 (es)
CN (1) CN107835821B (es)
AU (1) AU2016254693B2 (es)
BR (1) BR112017023437B1 (es)
CA (1) CA2983708C (es)
EA (1) EA201792366A1 (es)
MX (1) MX394142B (es)
SA (1) SA517390202B1 (es)
WO (1) WO2016174683A1 (es)
ZA (1) ZA201707454B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102906912B1 (ko) 2016-09-02 2026-01-05 사노피 파스퇴르 인크 네이세리아 메닌기티디스 백신
BR112019006278A2 (pt) 2016-09-30 2019-07-02 Biological E Limited composições de vacina pneumocócica multivalente que compreendem conjugados de polissacarídeo-proteína
EP3551668A1 (en) * 2016-12-06 2019-10-16 GlaxoSmithKline Biologicals S.A. Purification process for capsular polysaccharide
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
AU2019358622A1 (en) 2018-10-12 2021-06-17 Biological E Limited Multivalent pneumococcal polysaccharide-protein conjugate vaccine
WO2021064748A1 (en) 2019-10-01 2021-04-08 Biological E Limited Methods for quantification of carbohydrates
CA3159535A1 (en) * 2019-11-29 2021-06-03 Andreas Zurbriggen Method of purifying polysaccharides
CN116693706B (zh) * 2022-02-24 2024-10-11 成都生物制品研究所有限责任公司 一种肺炎链球菌荚膜多糖的纯化方法
CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
CA2059693C (en) 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5714354A (en) 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
WO1999039739A1 (en) * 1998-02-05 1999-08-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine Simplified method for removing free protein during preparation of protein-polysaccharide conjugates and vaccines using restricted-access media
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
ES2396955T3 (es) * 2006-07-06 2013-03-01 Reliance Life Sciences Pvt., Ltd. Procedimiento para la purificación de ácido hialurónico de elevado peso molecular
PT2074221E (pt) 2006-10-10 2010-09-06 Wyeth Llc Métodos melhorados para a separação de polissacáridos tipo 3 de streptococcus pneumoniae
PT2575870T (pt) * 2010-06-04 2017-02-10 Wyeth Llc Formulações de vacinas
BR112013024322B1 (pt) 2011-03-22 2020-04-22 Serum Inst India Ltd processo para preparação de polissacarídeos
CN103623401A (zh) 2012-08-23 2014-03-12 北京科兴中维生物技术有限公司 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法
IL312327B2 (en) * 2014-01-21 2026-02-01 Pfizer Immunogenic preparations comprising conjugated capsular saccharide antigens and their uses

Also Published As

Publication number Publication date
CN107835821B (zh) 2022-01-28
EA201792366A1 (ru) 2018-03-30
ZA201707454B (en) 2019-11-27
US10836839B2 (en) 2020-11-17
EP3288983A1 (en) 2018-03-07
MX394142B (es) 2025-03-24
BR112017023437B1 (pt) 2022-03-22
SA517390202B1 (ar) 2021-04-19
US20180155453A1 (en) 2018-06-07
CA2983708A1 (en) 2016-11-03
US20210017300A1 (en) 2021-01-21
EP3288983C0 (en) 2025-10-29
EP3288983B1 (en) 2025-10-29
WO2016174683A1 (en) 2016-11-03
JP2018514624A (ja) 2018-06-07
US11680111B2 (en) 2023-06-20
JP6882193B2 (ja) 2021-06-02
CA2983708C (en) 2023-09-19
BR112017023437A2 (pt) 2018-07-31
CN107835821A (zh) 2018-03-23
AU2016254693A1 (en) 2017-11-09
AU2016254693B2 (en) 2020-07-09

Similar Documents

Publication Publication Date Title
MX2017013855A (es) Metodo para la separacion de proteina y otras impurezas de polisacaridos capsulares microbianos.
PH12016502586A1 (en) Lipid comprising docosapentaenoic acid
ZA201908038B (en) Method for removal of impurities from bacterial capsular polysaccharide based preparations
MY178852A (en) Process for separating a synthetic turf product
WO2015112015A8 (en) Downstream processing of an alkaline phosphatase
GEP20196974B (en) A novel crystalline form of a benzimidazole derivative and a preparation method thereof
PH12016501515B1 (en) Method for producing vitamine e-enriched, especially tocotrienol-enriched, compositions from natural oils
MX2021006732A (es) Nanoemulsiones para bebidas producidas mediante un proceso de alto cizallamiento.
MY180732A (en) Protein manufacture
MX2017003301A (es) Producto refractario, relleno para fabricar el producto, procedimiento para fabricar el producto y uso del producto refractario.
MX2018014764A (es) Metodo para producir acido 3-hidroxiadipico.
IN2014MU00455A (es)
MY190747A (en) Method for producing silazane-siloxane copolymers and the use of such copolymers
MX359029B (es) Procedimiento para el tratamiento de enfermedades relacionadas con el factor inducible por hipoxia (hif) -.
IN2014CH00840A (es)
MX2018014769A (es) Metodo para producir acido a-hidromuconico.
MX2017008510A (es) Emulsion y proceso para elaborarla.
MX2023009431A (es) Metodo para crear un compuesto a base de mercurio, compuesto a base de mercurio, metodos de uso del compuesto a base de mercurio y usos del compuesto a base de mercurio.
PH12018502207A1 (en) Methods of manufacturing nutritional formulations
MD901Y (ro) Procedeu de tratare a seminţelor de castraveţi înainte de semănat
EP3109241A4 (en) Method of refining valsartan comprising more than 10% d-isomers
IN2013CH02496A (es)
MY188557A (en) Lipid comprising docosapentaenoic acid
MX2019006956A (es) Proceso para la fabricacion de derivados de diazepina.
MY194906A (en) Method for obtaining crystalline l-alanine